• 제목/요약/키워드: design sample

검색결과 3,075건 처리시간 0.028초

유전체 연관 연구에서의 검정력 및 연구대상수 계산 고찰 (A Review of Power and Sample Size Estimation in Genomewide Association Studies)

  • 박애경;김호
    • Journal of Preventive Medicine and Public Health
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    • 제40권2호
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    • pp.114-121
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    • 2007
  • Power and sample size estimation is one of the crucially important steps in planning a genetic association study to achieve the ultimate goal, identifying candidate genes for disease susceptibility, by designing the study in such a way as to maximize the success possibility and minimize the cost. Here we review the optimal two-stage genotyping designs for genomewide association studies recently investigated by Wang et al(2006). We review two mathematical frameworks most commonly used to compute power in genetic association studies prior to the main study: Monte-Carlo and non-central chi-square estimates. Statistical powers are computed by these two approaches for case-control genotypic tests under one-stage direct association study design. Then we discuss how the linkage-disequilibrium strength affects power and sample size, and how to use empirically-derived distributions of important parameters for power calculations. We provide useful information on publicly available softwares developed to compute power and sample size for various study designs.

자동차용 에어컨 응축기의 설계기술 개발 (Development of design technique for automotive condenser)

  • 조영두;한창섭;유성연
    • 설비공학논문집
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    • 제11권1호
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    • pp.10-17
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    • 1999
  • The present work presents condensation heat transfer and pressure drop data for the flow of R-12 in flat extruded aluminum tubes with small hydraulic diameters. The tube outside dimensions are $18mm(width){\times}1.7mm(height)$. Three types of internal geometry with the same outside dimensions are tested : sample 1 (7 tube holes), sample 2 (13 tube holes) and sample 3 (7 tube holes, micro-fin). The overall heat transfer coefficient is obtained for air-to-refrigerant heat transfer, and the Wilson plot method is used to determine the heat transfer coefficient for refrigerant flow. The sample 2 and sample 3 show significantly higher performance than sample 1. The heat transfer rates for the sample 2 and sample 3 are 9% and 12% higher, respectively, than sample 1. The friction factors for the sample 2 and sample 3 are 11.9% and 2.4% higher, respectively, than sample 1.

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경북인의 생활과 의식조사 표본설계 (A sample design for life and attitude survey of Gyeongbuk people)

  • 김달호;조길호;황진섭;정경하
    • Journal of the Korean Data and Information Science Society
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    • 제20권6호
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    • pp.1155-1167
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    • 2009
  • 2007년 경북인의 생활과 의식조사를 위한 표본설계를 연구하였다. 기존 조사에 대한 분석을 바탕으로 새로운 표본설계를 위한 여러 가지 사항을 검토하였다. 최근 시행된 2005년 인구주택총조사의 10% 표본조사자료를 조사모집단으로 사용하였고, 2006년 조사결과를 바탕으로 3가지 주요 항목 (경제활동상태, 연간소득수준, 주택소유)을 이용하여 표본조사구수에 대한 추정의 정도를 제시하고, 여러가지 층별 표본 배분을 검토한 후 비례배분을 사용하여 층별로 표본을 배분하고 적절한 표본의 크기를 결정하였다. 새로운 표본설계에서는 가중치를 계산하였고 이를 이용한 추정량과 추정오차 공식을 유도하여 기존의 단순집계를 벗어나 시군별 그리고 특성별 추정과 추정의 정도에 대한 평가를 가능하게 하였다.

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적응집락추출에서 표본크기 결정과 추정량의 효율 비교 (Determination of Sample Size and Comparison of Efficiency in Adaptive Cluster Sampling)

  • 낭궁평;원혜경;최재혁
    • 응용통계연구
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    • 제20권3호
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    • pp.605-618
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    • 2007
  • 모집단 단위들이 희박하게 존재하고 접근하기 어려운 경우에 적용하는 적응추출설계에서의 추출과정은 관심변수의 관측값에 의존한다. 동일한 표본크기에서 적응집락추출의 추정량은 단순임의추출의 추정량에 비해 효율이 더 좋다 적응추출에서 Rao-blackwell의 정리를 적용하여 Murthy의 추정량의 형태로 수정한 한센-휴비_(HH) 추정량과 호르비_-톰슨 (HT) 추정량은 기존의 추정량에 비해 작은 분산을 가진다. 본 연구는 초기표본을 바꿔가면서 기대표본크기와 적응추출의 표본크기 하의 단순임의추출의 추정량과 적응추출의 추정량의 효율을 비교하였다.

Soil sampling plan design of key facilities for denuclearization based on data quality objective process

  • Jeon, Yeoryeong;Kim, Yongmin
    • Nuclear Engineering and Technology
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    • 제54권10호
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    • pp.3788-3794
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    • 2022
  • The possibility of denuclearization of the Korean Peninsula has been continuously debated, and the initiative participation of the Republic of Korea has necessitated preemptive measures against neighboring countries. In this study, we present a proposal for formulating a site survey plan when the amount of site information provided is insufficient and the accuracy of the information is not guaranteed. Considering a case wherein "a soil sample analysis is used to determine the presence or absence of nuclear activity" in a radiochemical laboratory, which is a typical key facility for denuclearization, the optimal soil sample collection plan is designed based on international guidelines and public information. In the event of denuclearization, a scenario that is not based on the expertise of the sample collector is set, and the data quality objective (DQO) process is applied to ensure reality. Consequently, the primary sample collection points can be derived in consideration of accessibility, and the sample collection scale can be adjusted according to the cost. By applying the DQO process to ensure sample representativeness and reality, reliable and resource-efficient soil sample collection can be achieved in radiochemical laboratories and other denuclearization facilities.

Unbiased Balanced Half-Sample Variance Estimation in Stratified Two-stage Sampling

  • Kim, Kyu-Seong
    • Journal of the Korean Statistical Society
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    • 제27권4호
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    • pp.459-469
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    • 1998
  • Balanced half sample method is a simple variance estimation method for complex sampling designs. Since it is simple and flexible, it has been widely used in large scale sample surveys. However, the usual BHS method overestimate the true variance in without replacement sampling and two-stage cluster sampling. Focusing on this point , we proposed an unbiased BHS variance estimator in a stratified two-stage cluster sampling and then described an implementation method of the proposed estimator. Finally, partially BHS design is explained as a tool of reducing the number of replications of the proposed estimator.

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변량표본추출간격을 이용한 (equation omitted)x-R 관리도의 연구 (A study on the (equation omitted)x-R control chart with variable sampling interval scheme)

  • 이희춘
    • 산업경영시스템학회지
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    • 제18권33호
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    • pp.143-151
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    • 1995
  • In this design the sampling interval that each sampling time changes according to the valuse of the previous to sample statistics, sample mean and ranges. The VSI scheme uses large sample if the sample statistics appear near in side the control limits and smaller sample otherwise. The efficiency of the VSI scheme is compare to the FSI. It is shown that VSI control chart improves the confidence of the procedure and performens better than FSI control chart.

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가구 패널조사에서의 가중치 조정에 관한 연구 (A Study on the Weight Adjustment Method for Household Panel Survey)

  • 남궁평;변종석;임찬수
    • 응용통계연구
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    • 제22권6호
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    • pp.1315-1329
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    • 2009
  • 미국 노동통계청에서 사용하고 있는 BLS 방법의 효율성과 민감성에 관한 연구 결과에 의하면 표본 틀(Sample frame) 자료와 조사된 자료의 상관관계가 높을수록 BLS 무응답 보정 효과는 커지는 것으로 알려져 있다 (이석진과 신기일, 2008). 그러나 표본 틀 자료와 조사된 자료의 상관계수가 층별로 크기가 다른 경우, BLS 보정 효과는 달라질 수 있다. 따라서 일반적으로 실시되는 표본 설계에서는 층화추출 방법이 사용되기 때문에 각 층의 표본 크기와 상관계수가 다른 경우의 BLS 보정 효과률 살펴보는 것은 매우 중요하다. 본 논문에서는 층의 표본 크기와 상관계수 그리고 무응답 비율에 따른 BLS 무응답 보정 효과를 살펴보았다. 이를 위해 사용된 자료는 노동부의 월별 자료인 2007년 매월노동통계 자료이다.

Cluster Sampling in Sampling Inspection: Bayes Estimation

  • Juyoung Lee
    • Communications for Statistical Applications and Methods
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    • 제6권1호
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    • pp.107-116
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    • 1999
  • We propose a sample design which minimize Bayes risk for cluster smpling in sampling inspection. We treat a pilot sample and an additional sample size as random variable. In addition we compute an appropriate cluster size for handling over-dispersion.

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최소평균자승에러 알고리듬을 이용한 non-parametric 검파기 설계 (Design of Non-Parametric Detectors with MMSE)

  • 공형윤
    • 대한전자공학회:학술대회논문집
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    • 대한전자공학회 1998년도 추계종합학술대회 논문집
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    • pp.171-174
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    • 1998
  • A class of non-parametric detectors based on quantized m-dimensional noise sample space is introduced. Due to assuming the nongaussian noise as a channel model, it is not easy to design the detector through estimating the unknown functional form of noise; instead equiprobably partitioning m-dimensional noise into a finite number of regions, using a VQ and quantiles obtained by RMSA algorithm is used in this paper to design detectors. To show the comparison of performance between single sample detector and system suggested here, Monte-Carlo simulations were used. The effect of signal pulse shape on the receiver performance is analyzed too.

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