• Title/Summary/Keyword: design density

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Substituent Effect on the Structure and Biological Property of 99mTc-Labeled Diphosphonates: Theoretical Studies

  • Qiu, Ling;Lin, Jian-Guo;Gong, Xue-Dong;Cheng, Wen;Luo, Shi-Neng
    • Bulletin of the Korean Chemical Society
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    • v.33 no.12
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    • pp.4084-4092
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    • 2012
  • Theoretical calculations based on density functional theory (DFT) were performed to study the substituent effect on the geometric and electronic structures as well as the biological behavior of technetium-99m-labeled diphosphonate complexes. Optimized structures of these complexes are surrounded by six ligands in an octahedral environment with three unpaired 4d electrons ($d^3$ state) and the optimized geometry of $^{99m}Tc$-MDP agrees with experimental data. With the increase of electron-donating substituent or tether between phosphate groups, the energy gap between frontier orbitals increases and the probability of non-radiative deactivation via d-d electron transfer decreases. The charge distribution reflects a significant ligand-to-metal electron donation. Based on the calculated geometric and electronic structures and biologic properties of $^{99m}Tc$-diphosphonate complexes, several structure-activity relationships (SARs) were established. These results may be instructive for the design and synthesis of novel $^{99m}Tc$-diphosphonate bone imaging agent and other $^{99m}Tc$-based radiopharmaceuticals.

On-line Generation of Three-Dimensional Core Power Distribution Using Incore Detector Signals to Monitor Safety Limits

  • Jang, Jin-Wook;Lee, Ki-Bog;Na, Man-Gyun;Lee, Yoon-Joon
    • Nuclear Engineering and Technology
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    • v.36 no.6
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    • pp.528-539
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    • 2004
  • It is essential in commercial reactors that the safety limits imposed on the fuel pellets and fuel clad barriers, such as the linear power density (LPD) and the departure from nucleate boiling ratio (DNBR), are not violated during reactor operations. In order to accurately monitor the safety limits of current reactor states, a detailed three-dimensional (3D) core power distribution should be estimated from the in-core detector signals. In this paper, we propose a calculation methodology for detailed 3D core power distribution, using in-core detector signals and core monitoring constants such as the 3D Coupling Coefficients (3DCC), node power fraction, and pin-to-node factors. Also, the calculation method for several core safety parameters is introduced. The core monitoring constants for the real core state are promptly provided by the core design code and on-line MASTER (Multi-purpose Analyzer for Static and Transient Effects of Reactors), coupled with the core monitoring program. through the plant computer, core state variables, which include reactor thermal power, control rod bank position, boron concentration, inlet moderator temperature, and flow rate, are supplied as input data for MASTER. MASTER performs the core calculation based on the neutron balance equation and generates several core monitoring constants corresponding to the real core state in addition to the expected core power distribution. The accuracy of the developed method is verified through a comparison with the current CECOR method. Because in all the verification calculation cases the proposed method shows a more conservative value than the best estimated value and a less conservative one than the current CECOR and COLSS methods, it is also confirmed that this method secures a greater operating margin through the simulation of the YGN-3 Cycle-1 core from the viewpoint of the power peaking factor for the LPD and the pseudo hot pin axial power distribution for the DNBR calculation.

Predicted Performance of the Integrated Artificial Lighting System in Relation to Daylight Levels (채광시스템과 인공조명설비의 통합기술 및 성능평가연구)

  • Kim, G.;Kim, J.T.
    • Journal of the Korean Solar Energy Society
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    • v.22 no.3
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    • pp.47-56
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    • 2002
  • The office is an excellent candidate for implementing daylighting techniques because of the relatively high electric lighting power densities and long daytime use pattern. The quantity of light available for a space can be translated in term of the amount of energy savings through a process of a building energy simulation. To get significant energy savings in general illumination, the electric lighting system must be incorporated with a daylight - activated dimmer control. A prototype configuration of an office interior has been established and the integration between the building envelope and lighting and HVAC systems is evaluated based on computer modeling of a lighting control facility. First of all, an energy-efficient luminaire system is designed for both a totally open-plan office interior and a partitioned office. A lighting design and analysis program, Lumen-Micro 2000 predicts the optimal layout of a conventional fluorescent lighting fixture to meet the designed lighting level and calculates unit power density, which translates the demanded amount of electric lighting energy. A dimming control system integrated with the contribution of daylighting has been applied to the operating of the artificial lighting. Annual cooling load due to lighting and the projecting saving amount of cooling load due to daylighting under overcast diffuse sky are evaluated by a computer software, ENER-Win. In brief, the results from building energy simulation with measured daylight illumination levels and the performance of lighting control system indicate that daylighting can save over 70 percent of the required energy for general illumination in the perimeter zones through the year. A 25 % of electric energy for cooling may be saved by dimming and turning off the luminaires in the perimeter zones.

Analysis of the Vulnerable Area about Inundation on the Upriver Basin of Dam by Flood Simulation Using GIS (GIS 홍수 시뮬레이션에 의한 댐 상류 유역의 침수 취약지역 분석)

  • Um, Dae-Yong;Kim, Ji-Hye
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.27 no.6
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    • pp.723-731
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    • 2009
  • Recently, it has been strangely increasing rainfall and rainfall meter by global warming. so flood damage is being increase. It has happened there are so many damaged by influence by backwater of dam. However, the alleviative solutions of flood damages are focused on the lower river basin where the density of population is higher than upper river basin. This research proceeds based on design and build 3D topography model and reflects the topographical factors of upper river basin. It also simulated the circumstances of flooding by investigation of factors of outflow, hence, as a result, we would find out the vulnerable area for flooding and scale of damages effectively. This research suggests the solution and method of flooding for vulnerable area of the flooding to reduce the damages by predicting flooding. Thus, the suggestion may support to make a decision efficiently to prevent the damage of flooding.

Effect of Mix Ingredients on Modulus of Elasticity of High-Strength Concrete (고강도 콘크리트의 탄성계수에 미치는 배합재료의 영향평가)

  • 장일영;박훈규;이승훈;김규동
    • Journal of the Korea Concrete Institute
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    • v.14 no.1
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    • pp.67-75
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    • 2002
  • For the design of concrete structures in the serviceability limit state, the uniaxial static modulus of elasticity may be a most important parameter. In particular, this may be so just for a deflection control of the structure. Even in new concrete codes, however, the elastic modulus is normally presented on the form of general empirical relationships with the compressive strength and density of concrete. Normally, there is a large uncertainty associated with the general equations obtained by regression. Thus, in a typical plot of static modulus of elasticity vs. compressive strength, a large scatter can be observed at same strength. The aim of this study is to present the method for obtain the maximum modulus of elasticity at same compressive strength. In the present paper report the effects of mix ingredients on the modulus of elasticity of high-strength concrete. The test of 284 cylinder specimens arc conducted for type I with 11 % replacement of fly-ash cement concretes. Different water-hinder ratio, amounts of water and coarse aggregate as variables were investigated. And also analyzed it statistically by using SAS.

A Study on the Air Flow Characteristics in an Apartment Complex and Ventilation Performance of an Individual Unit for Improving IAQ (주동형태 변화에 따른 아파트 단지내 기류분석 및 단위주호의 환기성능에 관한 연구)

  • Lee, Jung-Hyun;Lee, Seung-Hee;Kim, Taeyeon
    • KIEAE Journal
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    • v.5 no.3
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    • pp.11-16
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    • 2005
  • The recent trends of high-density and high-rise in apartment housing have caused the problems of decrease in ventilation rates and increase of indoor pollutant contaminants. SHS(Sick House Syndrome) has now become a major issue and threats the health of residents. To solve these indoor air problems, increase in ventilation rate is considered as one of the most efficient approach. Thus, the recent housing development is pursuing improvement in the site design and the layout of apartment building blocks to promote natural ventilation is now investigated as one of the fundamental solutions. This study was focused on the air flow characteristics of outdoor environment in an apartment complex to keep the pollutants out of the site. Age of air and pressure difference have been used as indices of the outdoor air quality. Four different types of apartment building layouts have been analyzed by CFD simulation. This study again selected a real apartment housing complex as a case study model. By analyzing the pressure differences between the front and rear of an apartment building block, the ventilation performance in each individual unit was evaluated, and its impact on ventilation performance is investigated by analyzing the stagnant air around the apartment building blocks. During this process, existing patterns of apartment housing layout have been evaluated, and the most appropriate site layout has been chosen to analyze the outdoor airflow patterns. Based on the analysis of airflow patterns of site layout, the possibilities of improving ventilation performance of an individual apartment housing is proposed.

Optimal sensor placement for cable force monitoring using spatial correlation analysis and bond energy algorithm

  • Li, Shunlong;Dong, Jialin;Lu, Wei;Li, Hui;Xu, Wencheng;Jin, Yao
    • Smart Structures and Systems
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    • v.20 no.6
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    • pp.769-780
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    • 2017
  • Cable force monitoring is an essential and critical part of the safety evaluation of cable-supported bridges. A reasonable cable force monitoring scheme, particularly, sensor placement related to accurate safety assessment and budget cost-saving becomes a major concern of bridge administrative authorities. This paper presents optimal sensor placement for cable force monitoring by selecting representative sensor positions, which consider the spatial correlativeness existing in the cable group. The limited sensors would be utilized for maximizing useful information from the monitored bridges. The maximum information coefficient (MIC), mutual information (MI) based kernel density estimation, as well as Pearson coefficients, were all employed to detect potential spatial correlation in the cable group. Compared with the Pearson coefficient and MIC, the mutual information is more suitable for identifying the association existing in cable group and thus, is selected to describe the spatial relevance in this study. Then, the bond energy algorithm, which collects clusters based on the relationship of surrounding elements, is used for the optimal placement of cable sensors. Several optimal placement strategies are discussed with different correlation thresholds for the cable group of Nanjing No.3 Yangtze River Bridge, verifying the effectiveness of the proposed method.

Design and development of the clustering algorithm considering weight in spatial data mining (공간 데이터 마이닝에서 가중치를 고려한 클러스터링 알고리즘의 설계와 구현)

  • 김호숙;임현숙;용환승
    • Journal of Intelligence and Information Systems
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    • v.8 no.2
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    • pp.177-187
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    • 2002
  • Spatial data mining is a process to discover interesting relationships and characteristics those exist implicitly in a spatial database. Many spatial clustering algorithms have been developed. But, there are few approaches that focus simultaneously on clustering spatial data and assigning weight to non-spatial attributes of objects. In this paper, we propose a new spatial clustering algorithm, called DBSCAN-W, which is an extension of the existing density-based clustering algorithm DBSCAN. DBSCAN algorithm considers only the location of objects for clustering objects, whereas DBSCAN-W considers not only the location of each object but also its non-spatial attributes relevant to a given application. In DBSCAN-W, each datum has a region represented as a circle of various radius, where the radius means the degree of the importance of the object in the application. We showed that DBSCAN-W is effective in generating clusters reflecting the users requirements through experiments.

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User's responses to the type of campus layouts -Based on perceived safety and landscape visual preferences- ([캠퍼스 공간설계 유형에 따른 이용자의 지각반응특성에 관한 연구-안전지각과 시각선호에 대한 비교 분석-)

  • 엄붕훈;한성미
    • Journal of the Korean Institute of Landscape Architecture
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    • v.25 no.2
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    • pp.104.1-104.1
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    • 1997
  • The purpose of this study is to grasp the characteristics of user''''s response to perceived safety and visual preferences for outdoor green spaces by the types of campus layouts. This research was investigated by color slide ratings and questionnaire survey to the students who are majoring in Landscape architecture in three universities locating at Taegu area. Two research sites have similarities in many ways but have differences in campus land form and design type such as ''''Closed'''' and ''''Open'''' types. Major results were summarised as follows ; 1. As a result of the slide test, the high degree of visual preference was shown in the campus that is ''''Closed'''' type. However the degree of perceived safety was lower than that of in Youngnam Univ. campus. 2. According to the result of the comparative analysis between user''''s perceived safety and visual preferences in each campus, the degree of perceived safety at ''''Closed'''' type was lower than that of ''''Open'''' type, but the degree of visual satisfactioni was higher at ''''Closed'''' type. 3. The factors affecting visual preference in campus were shown as density of wood, land form, and diverse type of the spaces. On the other hand, the factors affecting perceived safety were ''''enclosed space by wood'''' at the day time, and ''''the condition of lighting'''' at night. 4. Regarding gender differences in sensation of each space variables, female users showed higher satisfactio on the scenic beauty. 5. Regression analysis showed that general satisfation was determined by the variables such as ''''arrangement'''', familiarity'''', ''''cleanness'''', and ''''closed feeling'''', in Kyungbook Univ. And in Youngnam Univ. , the variables were ''''texture'''', ''''perceived beauty'''', ''''cleanness'''', and ''''complexity'''' respectively. 6. In conclusion, campus users wanted the outdoor spaces that have various land form and somewhat ''''open-closed'''' mixture type, which has a good ''''Edge Effect'''' to satisfy both aspects in safety and visual preferneces.

User's responses to the type of campus layouts -Based on perceived safety and landscape visual preferences- ("캠퍼스" 공간설계 유형에 따른 이용자의 지각반응특성에 관한 연구-안전지각과 시각선호에 대한 비교 분석-)

  • 엄붕훈;한성미
    • Journal of the Korean Institute of Landscape Architecture
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    • v.25 no.2
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    • pp.104-116
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    • 1997
  • The purpose of this study is to grasp the characteristics of user's response to perceived safety and visual preferences for outdoor green spaces by the types of campus layouts. This research was investigated by color slide ratings and questionnaire survey to the students who are majoring in Landscape architecture in three universities locating at Taegu area. Two research sites have similarities in many ways but have differences in campus land form and design type such as 'Closed' and 'Open' types. Major results were summarised as follows ; 1. As a result of the slide test, the high degree of visual preference was shown in the campus that is 'Closed' type. However the degree of perceived safety was lower than that of in Youngnam Univ. campus. 2. According to the result of the comparative analysis between user's perceived safety and visual preferences in each campus, the degree of perceived safety at 'Closed' type was lower than that of 'Open' type, but the degree of visual satisfactioni was higher at 'Closed' type. 3. The factors affecting visual preference in campus were shown as density of wood, land form, and diverse type of the spaces. On the other hand, the factors affecting perceived safety were 'enclosed space by wood' at the day time, and 'the condition of lighting' at night. 4. Regarding gender differences in sensation of each space variables, female users showed higher satisfactio on the scenic beauty. 5. Regression analysis showed that general satisfation was determined by the variables such as 'arrangement', familiarity', 'cleanness', and 'closed feeling', in Kyungbook Univ. And in Youngnam Univ. , the variables were 'texture', 'perceived beauty', 'cleanness', and 'complexity' respectively. 6. In conclusion, campus users wanted the outdoor spaces that have various land form and somewhat 'open-closed' mixture type, which has a good 'Edge Effect' to satisfy both aspects in safety and visual preferneces.

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