• Title/Summary/Keyword: depth effect

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Biophysical Evaluation of Radiosensitization by AuNPs Nanoparticles Irradiated Photon beam (photon빔 조사 후 AuNPs 입자의 방사선 감수성 향상에 관한 생물물리학적 평가)

  • Choi, Eunae;Son, Jaeman
    • Journal of the Korean Society of Radiology
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    • v.10 no.7
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    • pp.483-487
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    • 2016
  • The purpose of this study is to investigate whether gold nanoparticles had radiosensitization when combined with gamma and x ray beam. Cytotoxicity was mearsured with comparing survival fraction after incubated time 6,12,18 and 24 hours. Clonogenic assay was employed to assess survival fraction of cells with and without gold nanoparticles treatment following gamma ray irradiation. The most of gold nanoparticles were distributed in the cytoplasm. And the toxicity of gold nanoparticles used this study were found to be non-cytotoxic. And we also observed enhancement by about 40% in RBE value for gamma ray irradiation of cells treated with gold nanoparticles. Dose reduction of about half for gamma ray irradiation is demonstrated for gold nanoparticles treated cells as compared to untreated cells. In cells with exposed to gamma ray, DNA damage was increased when compared to only radiation exposed cells. The study revealed a significant reduction in radiation dose for killing the cells with internalized gold nanoparticles as compared to the cells without gold nanoparticles. The gold nanoparticles treatment resulted in enhancement of radiation effect as evident from increase in relative biological effectiveness values for photon irradiated cells.

General Pharmacology of G009, a Polysaccharide Isolated from Ganoderma lucidum IY 009

  • Kim, Su-Ung;Lee, Seung-Yong;Lee, Seung-Mok;Jeong, Hoon;Hyun, Ik-Sang;Lee, June-Woo;Han, Man-Deuk;Lee, Eun-Bang;Cheon, Seon-Ah;Kim, Sang-Mee;Kim, Kyung-Ran
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1995.04a
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    • pp.106-106
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    • 1995
  • A polysaccharide, G009, isolated from Ganoderma lucidum IY009 subjected to investigating on general pharmacology. This material at the large oral doses of 1000 and 2000mg/kg in mice did neither exhibit any abnormal behaviors nor effects on central nervous system. It also had no influences on hexobarbital-induced sleeping time, rotarod test and spontaneous activity test at each oral dose of 1000mg/kg in mice. No effects on the body temperature and on acetic acid induced writhing syndrome in mice were observed with its oral administration at 1000mg/kg, and the convulsions induced by strychnine and pentetrazole were not inhibited at its oral doses of 1000mg/kg in mice. The solution of G009 as given intravenously at the doses of 30 and 60mg/kg in rabbit had no influences on blood pressure and respiration rates and depth. In isolated organs of rat uterus and fundus muscles and guinea-pig ileum and trachea, it did not show any contraction or relaxation at the concentration of 2$\times$10$^{-3}$g/ml, and the contractive actions produced by oxytocin, acetylcholine, serotonin and histamine did not inhibited by the same doses. This material showed no effect on intestinal propulsion test in mice and gastric secretion in rats at the oral doses of 1000mg/kg. However, it is interesting that the material exhibited potent inhibition of acidified aspirin induced gastric damage at the doses of 500 and 1000mg/kg in rats.

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Studies on the Development of weed Control Method for Paddy Rice by Bensulfuron-methyl Combination Suspension Concentrate (Bensulfuron-methyl 혼합(混合) 액상수화제(液狀水和劑)의 사용법(使用法) 개발(開發) 연구(硏究))

  • Ryu, G.H.;Park, J.E.;Lee, I.Y.;Lee, H.G.;Lee, J.O.;Park, Y.S.;Shin, H.S.
    • Korean Journal of Weed Science
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    • v.14 no.1
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    • pp.28-33
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    • 1994
  • This study was conducted to investigate the efficacy of weed control by pyributicarb{O-[3-tert-butylphenyl] N-[6-methoxy-2-pyridyl]-N-methyl thiocarbamate}/bensulfuron-methyl{methyl 2-[[[[[[4, 6-dimethoxypyrimidin-2-yl] amino] carbonyl] amino] sulfonyl] methyl] benzoate} SC and oxadiazon{5-tert-butyl-3-[2,4-dichloro-5-isopropoxyphenyl]-1,3,4-oxadiazol-2(3)-one}/bensulfuron-methyl SC, and to develope weed control methods for paddy rice. There was little difference between suspension concentrate and granule of pyributicarb/bensulfuron-methyl and oxadiazon/bensulfuron-methyl combination in the effect of weed control. Pyributicarb/bensulfuron-methyl SC and oxadiazon/bensulfuron-methyl SC were diffused from the point of application to 6m. Pyributicarb/bensulfuron-methyl SC applied on water surface from irrigation inlet and in paddy water from dike controlled more than 90% of weeds. Pyributicarb/bensulfuron-methyl SC was precipitated about 1-2cm per 1 hour after dripping on water surface. The efficacy of weed control by pyributicarb/bensulfuron-methyl SC was higher in 0-1cm than in 6-7cm standing water depth.

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Analysis of Geochemical Characteristics in the Intertidal Zone of Hyung-Do, Shi-Hwa Lake (시화호 형도 갯벌의 지화학적 특성 분석)

  • Lee, Jun-Ho;Jeong, Kap-Sik;Woo, Han-Jun;Cho, Jin-Hyung;Lee, Seung-Yong;Jang, Seok
    • Journal of Wetlands Research
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    • v.13 no.2
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    • pp.243-263
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    • 2011
  • In order to understand the sedimentary environment of the southern intertidal zone of Shihwa Lake, west coast of Gyeonggi-do, 10 surface and 2 core sediment samples were analysed for grain size, water content, AVS (Acid Volatile Sulfide), TOC (Total Organic Carbon), concentrations of metals (Al, Fe, Mn, Cu, As, Pb, Zn, Ni, Cd, and Cr). The surface sediments are generally poorly sorted (0.60~2.31 ${\phi}$) sandy Silt, slightly gravelly muddy Sand, silty Sand, Sand with mean grain size of 2.95 to 6.00 ${\phi}$. The sediments contain Al (1.54%), Fe (1.75%), Cu (9.1ppm), As (1.1ppm), Pb (18.8 ppm), Ni (11.0 ppm), Cd (0.02 ppm), and Cr (30.1 ppm) on the average. Heavy metals are concentrated less than ERL (Effect Range-Low), verified by NOAA (National Oceanic and Atmospheric Administration). In the core sediments, they are also less than the ERL. Based on the uniform vertical distribution of excess radioactivity of $^{210}Pb$, the core sediments seen to have been actively mixed biologically or rapidly deposited after the construction of Shi-Hwa Seawall. The 'enrichment factor' of metals, normalized to Al, shows that the upper sediments of 35 cm in depth are more polluted. infect was significant in 2 core sediment samples in 35 cm below layer.

A Study on Painting Layer Fixative Processing of Mural Paintings of Buddhist Temples in Korea (한국 사찰벽화 채색층 고착처리제 적용 연구)

  • Lee, Haw-Soo;Han, Kyeong-Soon;Lee, Sang-Jin
    • Journal of Conservation Science
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    • v.29 no.1
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    • pp.81-92
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    • 2013
  • In the past, European material and method were applied to conservation of Buddhist mural paintings in Korea. At that time, there were inadequate to selection of materials in consideration of porosity and hydrophilicity, therefore insufficiency to assessing their suitability for materials. The treatment result of mural painting are dissatisfied with consolidation of painting layer using synthetic resin. Therefore, it has experimented on applying fixative for reinforcement of painting layer on Buddhist mural painting in order to establish the effects of conservation. In relationship of binder's viscosity, adhesion and penetrating depth, adhesion increased in high-viscosity specimen whereas it decreased in low-viscosity specimen. While the binder's penetrating depths show similar patterns, the surface's response and combination adjacent to painting layer have differences. Animal glue and methyl cellulose (MC) shows excellent performance in their reaction with soil and painting layer. It is estimated that the fixative penetrates deep into soil to produce a stable fixing effect. The viscosity of polyvinyl acetate resin (PVAc) and acrylic resins are low, and thus penetrates well into soil, but they adhere poorly to soil.

Fresh Water Injection Test in a Fractured Bedrock Aquifer for the Mitigation of Seawater Intrusion (해수침투 저감을 위한 균열암반 대수층 내 담수주입시험)

  • Shin, Je-Hyun;Byun, Joong-Moo
    • Economic and Environmental Geology
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    • v.43 no.4
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    • pp.371-379
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    • 2010
  • Fresh water injection test in a fractured bedrock aquifer was applied as an efficient approach to lower saline concentrations in the saltwater-freshwater transition zone formed by seawater intrusion in a coastal area. The methodology and effectiveness of fresh water injection for hydraulically controlling seawater intrusion is overwhelmingly site dependent, and there is an urgent need to characterize the permeable fractures or unconsolidated porous formations which can allow for seawater flow and transport. Considering aquifer characteristics, injection and monitoring boreholes were optimally designed and completed to inject fresh water through sand layer and fractured bedrock, respectively. We devised and used the injection system using double packer for easy field operation and maintenance. Overall fracture distribution was systematically identified from borehole image logs, and the section of fresh water injection was decided from injection test and monitoring. With fresh water injection, the fluid electrical conductivity of the monitoring well started to be lowered by the inflow of fresh water at the specific depth. And this inflow leaded to the replacement of the fluid in the upper parts of the borehole with fresh water. Furthermore, the injection effect lasted more than several months, which means that fresh water injection may contribute to the mitigation of seawater intrusion in a coastal area.

Studies on the Purification of Sewage Water by Water Hyacinth (Eichhornia crassipes) (1부레옥잠에 의한 생활오수(生活汚水)의 정화효과(淨化效果))

  • Kim, Bok-Young;Lee, Sang-Kyu;Kwean, Chang-Seag;So, Kyu-Ho;Yun, Eun-Ho
    • Korean Journal of Environmental Agriculture
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    • v.10 no.1
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    • pp.51-57
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    • 1991
  • Field experiments were carried out to evaluate the utility of water hyacinth(Eichhornia crassipes Solm-Laub) for purifyng sewage water in paddy fields of $247m^2$(75 Pyung). A field was lined with PVC film at a depth of 30cm and sewage water for 40 days. The results obtained with the use of water hyacinth in the sewage water are summarized as follows : 1. The Sodium linear dodecyl benzene sulfonate content of sewage water on the inlet was 6.33 ppm, themiddle point was 3.50 ppm and the outlet was 1.37 ppm. 2. With the use of water hyacinth in the sewage and the distilled water, the L.A.S. content were decreased from 7.3 and 4.0 to 0, respectively. 3. Sterillization with 70% ethyl alcohol at the roots of the water hyacinth was reduced the degradation effect of L.A.S. 4. The COD and $NH_4^+-N$ content of the sewage decreased from 107 and 32.7 ppm to 32.6 and 16.2 ppm, respectively and the P, Na and Cl content also were reduced.

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A Study on the Method for Ecological Restoration on Abandoned Concrete-paved Road - Focused on the Experimental Construction Site in Young Dong Province of GyungBu Express Highway(227.24~229.04km) - (콘크리트 폐도의 생태복원 방안 모색에 관한 연구 - 경부선 영동군 황간지역 시험시공지를 중심으로(경부고속도로 227.24~229.04km 지점) -)

  • Kim, Nam Choon;Ann, Phil Gun;No, Su Dae;Kim, Do Hee
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.15 no.4
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    • pp.119-132
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    • 2012
  • The unmanaged abandoned concrete roads are vulnerable toward the issues on soil and water pollution, which requires flexible managing method such as eco-corridor after the process of ecological restoration. Among various alternations of abandoned concrete-paved roads, ecological restoration technique may be the most suitable method in sites including high quality of natural environment. Therefore, as in Young dong province, GyungBu express highway (227.24~229.04km), which is near to Hwang-gan IC, the survey to measure its effect of soil under the paving and water pollution by abandoned concrete roads was discussed. Then, the restoration method of plantings of landscape trees and hydro-seeding methods of artificial soil media was appraised through consecutive monitoring. The soil adequacy analysis shows lower percentage of heavy metal substance in each depth level compared to standard limit stated by the Ministry of Environment, along with low concerns raised after the analysis on heavy metal content of the spilled water on the concrete roads. Meanwhile, Korean Weigela (Weigela subsessilis L.H. Baily) was found to be withered in small-scale landscape trees planting sites. Among the seeding plants. the family of leguminosae, Silene armeria, Dendranthema boreale, Caryopteris incana and Aster yomena show good establishment results. Overall studies on planting of small and large landscape trees, planting method of container plants, planting method of ground cover plants, and germination and development trend of seeding plants of the experimental restoration site on abandoned concrete roads are revealing specific trends in the way landscape woody plants establishment and growth. Finally, this study suggests further studies and survey on varied plant restoration methods on abandoned concrete-roads for developed design guidelines of their methods.

Effect of Applications of Swine Waste and Chemical Fertilizer on Productivity of Silage Corn and Nitrogen and Phosphorus Leaching in Lysimeter (Lysimeter에서 돈분 및 화학비료의 시용수준이 옥수수의 생산성 및 N과 P의 용탈에 미치는 영향)

  • 육완방;김범준;최기춘;곽병관
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.22 no.2
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    • pp.85-92
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    • 2002
  • This study was conducted to investigate the effects of application levels of swine waste and chemical fertilizer on productivity of corn and nitrogen and phosphorus leaching in Lysimeter containing sandy loam soil. Main Plots were consisted of two types of swine waste, such as swine slurry(SS) and compost of swine manure fermented with sawdust(CSMFS), and chemical fertilizer(CF) and the subplots were consisted of application levels of N-fertilezer, such as 100kgN/ha, 200kgN/ha and 400kgN/ha. Lysimeters were constructed with 1m depth, 30cm diameter. The results obtained were summarized as follows ; 1. Dry matter(DM) yield of com enhanced as increased application levels of SS, CSMFS and CF. DM yield reveals that there is an increase in order CS > SS > CSMFS. 2. Nitrogen contents of the whole corn enhanced as increased application levels of SS, CSMFS and CF. Nitrogen content reveals that there is an increase in order CS > SS > CSMFS. 3. $NO_3^{-}$ and P contents in the leaching water increased as increased application levels of SS, CSMFS and CF. $NO_3^{-}$ content was highly elevated in the concentrated rainy season in the experimental early stage. However, P content was affected with the rainfall. The maximum $NO_3^{-}$ and P contents in the leaching water were 14.8ppm and 0.26ppm, respectively.ively.

Studies on the Grassland Management in Late-Autumn and Early-Spring V. Effect of fertilizer application time in early spring on growth, yield and nutritive value of grasses for hay (월동전후 초지관리에 관한 연구 VI. 봄철 건초이용초지에서 이른 봄 추비시용시기가 목초의 생육과 수량 및 사료가치에 미치는 영향)

  • Kim, Jae-Kyu;Seo, Sung
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.9 no.3
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    • pp.148-152
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    • 1989
  • This field experiment was carried out to determine the effects of fertilizer application time in early spring on growth, dry matter (DM) yield, crude protein (CP) content, crude protein yield (CPY), N recovery, acid detergent fibej (ADF) content and DM digestibility (DMD) of grasses for hay. Application times of fertilizer were March 10, 20, 30, April 9. 19, and control (non-fertilized) plot was involved. The fust harvesting data for hay was May 9 (early heading stage) and the regrowth yields were investigated for soiling, 1989. In all fertilized plots, the growth, DM yield, CP, CPY and N recovery of grasses were significantly increased compared with control, and the best grass growth, DM yield, CP, CPY, N recovery and DMD were observed on March 20 and 30 among all fertilized plots. On March 20 and 30 in this experiment, the accumulated temperature was 200 and 280^{\circ}C.$, and the subsoil temperature at 10 cm depth was 8 and 10^{\circ}C.$. Considering the average meteorological condition in Suwon area, the optimum application time of early spring for hay may be recommended from April 10 to 15. i\ulcornerfW3U% (L. westock Experiment Station, RDA. Suwon 440 - 350. Korea)

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