• 혜화의학회지
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• 제19권2호
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• pp.187-193
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• 2011

Purpose : This paper is aim to report the effects of Gamisoyosan(加味逍遙散) on the UL-syndrome(鬱症) Methods : This is two cases report of female patient suffering from headache, chest discomfort, heart burning, insomnia, dyspepsia, anorexia, fatigue and other symptoms due to chronic stress. 52 years old woman who diagnosed UL-syndrome(鬱症) was enrolled in this study. We gave her Gamisoyosan(加味逍遙散) 2 times, each for 3 weeks. During the treatments, we check changes of symptoms and HRSD. Results : After the oriental medical treatments, symptoms of UL-syndrome(鬱症) were decreased or disappeared. Conclusion : This clinical case indicate that Gamisoyosan(加味逍遙散) is effective in treatment of the depression disorder and symptoms of UL-syndrome(鬱症). More clinical data and studies are requested for the treatment of UL-syndrome(鬱症).

• 생물정신의학
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• 제18권4호
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• pp.189-196
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• 2011

Major depressive disorder is characterized by cellular and molecular alterations resulting in the depressive behavioral phenotypes. Preclinical and clinical studies have demonstrated the deficits, including cell atrophy and loss, in limbic and cortical regions of patients with depression, which is restored with antidepressants by reestablishing proper molecular changes. These findings have implicated the involvement of relevant intracellular signaling pathways in the pathogenetic and therapeutic mechanisms of depressive disorders. This review summarizes the current knowledge of the signal transduction mechanisms related to depressive disorders, including cyclic-AMP, mitogen-activated protein kinase, Akt, and protein translation initiation signaling cascades. Understanding molecular components of signaling pathways regulating neurobiology of depressive disorders may provide the novel targets for the development of more efficacious treatment modalities.

• 생물정신의학
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• 제17권1호
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• pp.5-14
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• 2010

Depressive disorder is a chronic disabling condition with recurrent episodes. Medication noncompliance is a significant problem for effective management of depressive disorder. However, compliance with antidepressant medication is poor. There are difficulties in assessing compliance accurately. Various methods for assessing compliance are in use. A patient's compliance with antidepressant may be affected by many factors including the clinical characteristics of depression, pharmacologic properties of antidepressants, patients' characteristics, accessibility treatment, and doctor-patient relationships. For enhancing the treatment compliance, psychotherapeutic considerations in patient-therapist relationship are needed.

• Journal of Korean Medical Science
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• 제33권47호
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• pp.300.1-300.17
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• 2018

Parkinson's disease (PD) is the second most common neurodegenerative disorder. Although its major manifestation is motor symptoms, resulting from the loss of dopaminergic neurons in the substantia nigra, psychiatric symptoms, such as depression, anxiety, hallucination, delusion, apathy and anhedonia, impulsive and compulsive behaviors, and cognitive dysfunction, may also manifest in most patients with PD. Given that the quality of life - and the need for institutionalization - is so highly dependent on the psychiatric well-being of patients with PD, psychiatric symptoms are of high clinical significance. We reviewed the prevalence, risk factors, pathophysiology, and treatment of psychiatric symptoms to get a better understanding of PD for improved management.

• 동의신경정신과학회지
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• 제24권spc1호
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• pp.15-22
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• 2013

Objectives : The Hwabyung Research Center of The Korean Society Of Oriental Neuropsychiatry attempted to produce clinical guidelines for doctors of Korean medicine for the treatment of Hwabyung. Methods : A standard guideline development process was followed. Relevant literature was identified by a review of bibliographies. The operational criteria were used to rate the quality of scientific evidence, and the line of treatment recommendations included a consensus clinical opinion. This section of "the status of Hwabyung in Korea" is 2 out of 5 articles drafted and reviewed by clinicians. Results : Hwabyung is changed depending on the time and have a risk of relapse. Like the previous studies, Female and lower socio-economic and educational level people suffers Hwabyung frequently. But recently number of Male Hwabyung patients increases. Recovery of Hwabyung is involved in depression, anxiety, stress. Hwabyung is related to Major depressive disorder, generalized anxiety disorder, somatoform disorder and diseases of the digestive system. Conclusions : This study was observed for the progression of Hwabyung. Hwabyung is a long-term disease associated with depression, anxiety and stress. Hwabyung is accompanied by physical and psychological symptoms and degrades the quality of life.

• Child Health Nursing Research
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• 제24권3호
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• pp.337-344
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• 2018

Purpose: The purpose of this study is to examine the association between each phase of the Life Transition Process (LTP) and depressive symptoms among parents of children with Autism Spectrum Disorder (ASD). Methods: Using a cross-sectional study design, data pertaining to LTP and depressive symptoms were collected from 285 parents of children with ASD (101 fathers and 184 mothers). Participants were recruited through the Autism Society of Korea and a counseling center for families of children with ASD. Results: Using a cut-off point of 5 or higher on the Beck Depression Inventory-Short Form, more than half of the parents (53.4%) were deemed depressed; these parents experienced moderate (27.4%) to severe (11.6%) levels of depressive symptoms. A hierarchical multiple regression using the socio-demographic characteristics of children and parents and each phase of the LTP as predictors, found that lower income (${\beta}=-.14$, p=.007) and greater scores for the wandering phase (${\beta}=.59$, p<.001) were significant predictors of greater levels of depressive symptoms. Conclusion: These findings confirm the association between LTP and depressive symptoms for parents of children with ASD, who were found to have a greater risk of depressive symptoms during wandering phase.

• 혜화의학회지
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• 제18권1호
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• pp.49-66
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• 2009

1. Hiccup is usually named as Hae yek, Hyel yek, Yel yek. 2. The cause of hiccup are stomach cold, rising of stomach fire, stagnation of vital energy and stagnationof phlegm, yang deficiency of spleen and kideny, deficiency of stomach-yin, or mental disorder due to the stagnation of phlegm, dyspepsia, depressed vital energy. 3. Vicera and Bowels related with Hiccup are lung, spleen, stomach, and heart. 4. The treatment of hiccup are dispel cold by warming the middle warmer due to stomach cold, expel the heat-evil to loose hollow-organ due to rising up of stomach yin, regulate vital energy and dissipate phlegm due to stagnation of vital energy and stagnation of phlegm, warm and recuperate both of spleen and kidney due to spleen and kidney yang deficiency, nourish the stomach to promote the production of body fluid due to deficiency of stomach yin. 5. Regarding neuropsychiatric aspect of hiccup, qi movement disorder was the main mechanism of disease and qi depression was the main cause. The prescriptions for neuropsychiatric hiccup were Mokhwangjogisan Pyunjakjunghyangsan, Daegwakhyangsan, and Haeaedan.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제30권4호
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• pp.153-160
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• 2019

Objectives: This study aimed to evaluate the addiction to highly caffeinated drinks among university students, and we investigated the relationships between smartphone addiction, depression, anxiety, attention-deficit/hyperactivity disorder (ADHD), burnout, self-esteem, impulsiveness in high caffeine drink addiction risk group (high caffeine group). We also compared these mental health factors differences between the high caffeine group and the control group; and, investigated the relative risk between the independent variables of the high caffeine group. Methods: This study was conducted in Korea, from June 2015 to July 2016. A set of questionnaires was administered on 511 college students. Results: The participants who belonged to the high caffeine group were more likely to demonstrate the symptoms of ADHD and higher levels of burnout and impulsiveness. Further, the results of logistic regression analysis confirmed the association between the high caffeine group and burnout. Conclusion: These behaviors among university students addicted to highly caffeinated drinks suggests the need for timely and effective interventions for those at risk of addiction.

• 동의신경정신과학회지
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• 제27권2호
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• pp.103-117
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• 2016

Objectives The purpose of this study was to introduce Chinese Taoist Cognitive Psychotherapy (CTCP), a psychotherapy based on Oriental culture, and review related research to understand its efficacy.Methods Relevant articles were searched from CNKI, WANFANG, Pubmed, EMBASE, AMED and CENTRAL.Results Thirty-seven studies were selected based on our inclusion criteria, which included 31 RCTs. The overall risk of bias of the RCTs was unclear or high. In the total relevant studies, the target diseases were most commonly depression and anxiety disorder. Generally, CTCP combined with Western medicine was significantly more effective than prescribing medicine alone.Conclusions CTCP can be useful for several psychiatric disorders including depression and anxiety disorder; however, more high-quality clinical trials are needed to confirm its efficacy.

• 대한불안의학회지
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• 제9권1호
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• pp.68-73
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• 2013

Objective : The aim of this study is to identify the relationship between childhood abuse and affective symptom including resilience in patients with depression or anxiety. Methods : A total 256 outpatients diagnosed with depressive disorder or anxiety disorder according to DSM IV-TR, were evaluated with Beck Depression Inventory (BDI), State-Trait Anxiety Inventory (STAI), Parent-Child Conflict Tactics Scale (PCCTS), Connor-Davidson Resilience Scale (CD-RISC). Independent t-test, Chi-square analysis and analysis of covariance (ANCOVA) were performed to identify the demographics of patients and the relationship between affective symptoms including resilience and childhood abuse. Results : Among demographic and clinical variables, patients with childhood abuse history were significantly higher rate in patients who were living alone and unemployed. In affective symptoms, patients with childhood abuse history were significant more severe in depressive symptoms, and state anxiety score than patients without history of childhood abuse. Patients with childhood abuse history had higher score for trait anxiety and lower score for resilience than patients who had no history of childhood abuse. Conclusion : These finding suggest that history of childhood abuse might be risk factor on depressive and anxiety symptoms severity. And this might be a predictable factor of poor treatment outcome.