• Journal of Oral Medicine and Pain
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• 제43권1호
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• pp.16-20
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• 2018

Graft-versus-host disease (GVHD) is frequent complications of hematopoietic stem cell transplantation. In the chronic GVHD (cGVHD), the oral cavity is the most commonly affected region. The clinical manifestations include erythema, ulceration, lichenoid-hyperkeratotic change in oral mucosa, dry mouth, and limitation of mouth opening. The initial treatment strategy of oral cGVHD patients is topical corticosteroid therapy in various formulation. However, corticosteroid resistance appears in some patients. We report a case of a 25-year-old male patient with oral cGVHD, who has resistance to topical corticosteroid medication, treated with 0.03% tacrolimus ointment and low-dose doxycycline. The patient showed subjective and objective improvement without side effect.

• Restorative Dentistry and Endodontics
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• 제41권3호
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• pp.202-209
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• 2016

Objectives: The purpose of this study was to investigate the involvement of TRPA1 in the cinnamaldehyde-induced pulpal blood flow (PBF) change in the feline dental pulp. Materials and Methods: Mandibles of eight cats were immobilized and PBF was monitored with a laser Doppler flowmetry at the mandibular canine tooth. To evaluate the effect of cinnamaldehyde on PBF, cinnamaldehyde was injected into the pulp through the lingual artery at a constant rate for 60 seconds. As a control, a mixture of 70% ethanol and 30% dimethyl sulfoxide (DMSO, vehicle) was used. To evaluate the involvement of transient receptor potential ankyrin 1 (TRPA1) in PBF change, AP18, a specific TRPA1 antagonist, was applied into the pulp through the Class V dentinal cavity followed by cinnamaldehyde-administration 3 minutes later. The paired variables of experimental data were statistically analyzed using paired t-test. A p value of less than 0.05 was considered as statistically significant. Results: Administration of cinnamaldehyde (0.5 mg/kg, intra-arterial [i.a.]) induced significant increases in PBF (p < 0.05). While administration of a TRPA1 antagonist, AP18 (2.5 - 3.0 mM, into the dentinal cavity [i.c.]) caused insignificant change of PBF (p > 0.05), administration of cinnamaldehyde (0.5 mg/kg, i.a.) following the application of AP18 (2.5 - 3.0 mM, i.c.) resulted in an attenuation of PBF increase from the control level (p < 0.05). As a result, a TRPA1 antagonist, AP18 effectively inhibited the vasodilative effect of cinnamaldehyde (p < 0.05). Conclusions: The result of the present study provided a functional evidence that TRPA1 is involved in the mechanism of cinnamaldehyde-induced vasodilation in the feline dental pulp.

• 디지털융복합연구
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• 제14권11호
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• pp.449-457
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• 2016

본 연구에서는 과일즙이 복합레진의 표면부식과 착색에 미치는 영향을 알아보고자 일상적으로 많이 섭취하는 과일 중 산도가 높고 색깔이 있는 포도, 레몬, 오렌지, 자몽, 키위 5종을 선정하고 레진시편을 제작하여 과일즙에 침지하였다. 레진시편은 $37^{\circ}C$에서 과일즙에 3일, 7일 간격으로 침지하였다. 대조군은 과일즙에 침지하지 않은 레진으로 하였다. 시간에 따른 표면의 변화는 주사전자현미경을 이용하여 관찰하였으며 착색정도의 변화는 분광광도계를 이용하여 측정하였다. 주사전자현미경으로 레진의 표면변화를 관찰한 결과, 대조군에 비해 실험군은 표면 입자간의 홈의 크기가 증가하였고 직사각형모양의 막대상의 구조가 생겨났으며 작게 돌출된 돌기상의 입자가 사라지는 양상을 보였다. 분광광도계로 레진의 착색정도를 측정한 결과, 실험군 간의 차이는 포도즙에 침지한 경우 명도가 가장 어두운 것을 볼 수 있었다.

• International Journal of Oral Biology
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• 제31권1호
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• pp.15-20
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• 2006

Concerns remain regarding the biocompatibility and adverse effects of dental casting alloys. The aim of this study was to understand the cytopathogenic effect of metal ions, which might be released from dental alloys, on oral squamous carcinoma(OSC) cells. The cellular morphology, viability, the type of cell death and molecular change in response to metal ion salt solutions including aluminum(Al), cobalt(Co), copper(Cu) and nickel(Ni) were examined. The $TC_{50}$ values for the metal ions with the exception of AI were estimated to be between 400 and $600{\mu}M$. The cells treated with the metal ions showed apoptotic change with the exception of Al ions. Metal ion-induced apoptosis was further confirmed using flow cytometric analysis. This study showed that the cytotoxicity and the mode of cell death by metal ions clearly depend on the cell type, the type of metal ion and the duration of exposure. The protein level of Rb, a tumor suppressor that affects apoptosis para-doxically, was higher in the cells treated with Co, Cu and Ni. It is believed that apoptosis and cell damage in the OSC cells treated with Co, Cu or Ni can be evoked by the regulation of Rb.

• 한국치위생학회지
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• 제1권1호
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• pp.19-37
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• 2001

The purpose of this study was to develop effective oral health education programs for mentally retarded children and promote their oral health, by offering oral health education for 45 mentally retarded children between age 6 to 20, tracking the change of their knowledge depending on the frequency of education, and examining the educational effect before and after oral health education. The children with mental retardation attended a special school for idiots in Gweonseon-gu, Suwon, Kyonggi Province, being able to take training(IQ 25-49). The education program was designed to be suitable for their cognitive power after consultation with a special school teacher. A teacher provided the same education seven times, once a week, and an interview was held with each of them to assess their correct answer rate. The findings of this study were as below: 1. The repeated oral health education served to have the children with mental retardation acquire better knowledge about harmful food for the teeth, what had to be done after eating cookies or candies between meals, the right time for toothbrushing, the concept of dental caries, and how to cope with dental caries(p<0.01). But after that education was offered four times, the frequency of that education made no difference. 2. The repeated oral health education increased, their knowledge on the role of the teeth and the right choice of toothbrush(p<0.01), yet there was no significant difference in their knowledge about oral health behavior, because they had already been familiar with that. 3. As a result of investigating the change of their oral health know-ledge before and after oral health education according to the type of handicap, the type of handicap made no significant difference to the change of their oral health knowledge. 4. The oral health education for the children with menial retardation had a significantly different effect on their knowledge about harmful food for the teeth, what had to be done after eating between meals, the right time for toothbrushing, the role of the teeth. the right choice and use of toothbrush, how to do toothbrushing, and fluorine(p<0.01).

• 치위생과학회지
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• 제10권6호
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• pp.459-464
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• 2010

본 연구는 실리콘 고무인상재의 보관온도에 따른 작업 시간과 압축 시 변형율, 탄성회복율, 점조도에 관한 물리적 특성에 대해서 평가하였으며, 다음과 같은 결과를 얻었다. 1. 작업시간은 저온의 온도유지장치에서 보관한 인상재가 실온이나 고온에서 보관한 인 상재보다 유의하게 크게 나타났고(P<0.05), 실온과 고온에서 보관한 인상재는 유의차 가 없었다. 2. 압축변형율은 저온 온도유지장치에서 보관한 인상재가 실온이나 고온에서 보관한 인 상재보다 유의하게 컸으며(P<0.05), 실온과 고온에서 보관한 인상재는 유의차가 없 었다. 3. 탄성회복율은 인상재를 보관한 각 저장온도에 따라 유의한 차이가 있는 것으로 나타 났으며(P<0.05), 온도가 높아짐에 따라 증가하였다. 4. 점조도는 인상재를 보관한 각 저장온도에 따라 유의한 차이가 있는 것으로 나타났으 며(P<0.05), 온도가 높아짐에 따라 감소하였다.

• 한국치위생학회지
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• 제7권3호
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• pp.301-316
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• 2007

With these changes in the environment of dental service, dental hygienists are suggested to change their roles to cope with the changes. Hygienists are putting forth many efforts to promote smooth and efficient dental treatments, and as a practical measure. As a part to cope with such changes. Korea Dental Hygienists Association(KDHA) has prepared the system of Specialized Dental Hygienist and put the system into enforcement through an affiliated organization, Korean Academy of Dental Hygiene. The purpose of this study is to investigate the specialized nurse system in our country's medical environment and the specialized dental hygienist systems in other countries as similar cases comparable to the specialized dental hygienist system in our country and present basic data for the establishment of specialized dental hygienist system. For this study, a survey of dental specialists, such as dentists, dental hygienists and nurses, and patients, has been conducted qualitatively through person-to-person depth interview. The interview questions were related to the need for a specialized dental hygienist system, educational programs, functions and roles, and issues that must be solved for establishment of the system. Based on the interview results, the following conclusions were derived. The specialized dental hygienist system must encourage dental hygienists to possess advanced abilities in clinical practices, present systematic and developmental directions in educational programs, and stimulate specialized dental hygienists to actively work as manager and supervisor, medical health service providers, educators, and researchers. Lastly, for issues that must be solved for the establishment of the system, the duties and jobs of specialized dental hygienists must be defined more concretely, which must be acknowledged by people working in related occupations, citizens and the government. Furthermore, we need to examine the scope of duties of dental hygienists and enact laws and systems to protect the scope. These roles will lead dental hygienists to lay the foundation that allow them to make enthusiastic activities as an oral hygienist and clinician as well as show the way how to act as an educator, a researcher, a manager and an administrator.

• 치과방사선
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• 제22권1호
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• pp.128-136
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• 1992

This study was undertakened to investigate the change of image characteristics on dental films according to the process of using time of processing solution in automatic processor. Base + fog density, film density and subject contrast were measured with the digital densitometer, the pH of developing and fixing solution were measured with Digital pH / ION Meter. The following results were obtained: 1. Base + fog density was increased with the process of using time of the processing solution and was over the maximum permissible base + fog density 0.25 from the 3rd day. 2. Film density was increased with the process of using time of the processing solution. 3. Subject contrast was decreased with the process of using time of the processing solution. 4. The pH of the developing solution was decreased with the process of using time, the pH of the fixing solution was increased.

• 대한치과기공학회지
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• 제17권1호
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• pp.5-9
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• 1995

This study was carried out by obsorving to the conditions of an oxide on the surface of alloy according to the conditions of its heat treatment and analysing the change in composition on its surface. The result of this study is summarized as fellows. 1. It was shown that the higher the more the generated metal oxide while the higher the temperature of heat treatment. 2. The metal oxide was manily composed of Ni and Cr oxides. 3. The Ni composition indicated reduction while the higher the heat treatment in vaccum condition. 4. The Cr composition indicated increase while the higher the heat treatment in vaccum condition.

• Journal of Oral Medicine and Pain
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• 제43권4호
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• pp.142-146
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• 2018

Patients with temporomandibular disorder often present with acute occlusal change and properly managed with conservative treatment. If such change is caused by unusual etiology, differential diagnosis may be challenged. This article describes the diagnosis of a patient exhibiting pain and acute posterior open bite on the ipsilateral side after chewing hard food. After initial conservative treatment failed to resolve the complaint, magnetic resonance imaging was ordered and confirmed partial perforation of articular disc. Disc perforation itself is usually chronic in nature, but sudden macrotrauma may also cause the disorder. However, occlusal discrepancy caused by disc perforation is rare and seldom reported. We present a case of acute malocclusion caused by disc perforation with a review of related literature.