• Archives of Plastic Surgery
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• 제45권6호
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• pp.504-511
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• 2018

Background Acellular dermal matrix (ADM) helps wound healing by stimulating angiogenesis, acting as a chemoattractant for endothelial cells, providing growth factors, and permitting a substrate for fibroblasts to attach. The current standard for using paste-type ADM (CG Paste) in wound healing is direct application over the wounds. The major concerns regarding this method are unpredictable separation from the wounds and absorption into negative-pressure wound therapy devices. This study aimed to investigate the effects of subcutaneous injection of paste-type ADM on wound healing in rats. Methods Full-thickness skin defects were created on the dorsal skin of rats. Eighteen rats were randomly divided into three groups and treated using different wound coverage methods: group A, with a saline dressing; group B, standard application of CG Paste; and group C, injection of CG Paste. On postoperative days 3, 5, 7, 10, and 14, the wound areas were analyzed morphologically. Histological and immunohistochemical tissue analyses were performed on postoperative days 3 and 7. Results Groups B and C had significantly less raw surface than group A on postoperative days 10 and 14. Collagen fiber deposition and microvessel density were significantly higher in group C than in groups A and B on postoperative days 3 and 7. Conclusions This study showed comparable effectiveness between subcutaneous injection and the conventional dressing method of paste-type ADM. Moreover, the injection of CG Paste led to improved wound healing quality through the accumulation of collagen fibers and an increase in microvessel density.

• Journal of Microbiology and Biotechnology
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• 제11권6호
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• pp.979-985
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• 2001

A fluorometric detection technique for HDL (High Density Lipoprotein) and LDL (Low Density Lipoprotein) was developed for application in a fiber-optic immunosensor using a protein A Langmuir-Blodgget (LB) film. For the fluorescence immunoassay, antibodies specific to HDL or LDL were imobilied on the protein A LB film, and a fluorescence amplification method was developed to overcome their weak fluorescence. The deposition of protein A using the LB technique was monitored using a surface pressure-are $({\pi}-A)$ curve, and the antibody immobilization of the protein A LB film was experimentally verified. The immobilized antibody was used to separate only HDL and LDL from a sample, then the fluorescence of he separated HDL or LDL was amplified. The amount of LDL or HDL was measured using the developed fiber optic fluorescence detection system. The optical properties resulting from the reaction of HDL or LDL with o-phtaldialdehyde, detection range, response time, and stability of the immunoassay were all investigated. The respective detection ranges for HDL and LDL were sufficient to diagnose the risk of coronary heart disease. The amplification step increased the sensitivity, while selective separation using the immobilized antibody led to linearity in the sensor signal. The regeneration of the antibody-immobilized substrate could produce a stable and reproducible immunosensor.

• KSBB Journal
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• 제14권6호
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• pp.677-681
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• 1999

계란의 난황으로부터 유래한 IgY의 분리와 정제과정이 흐름을 정리한 결과, 난황에서의 수용성 단백질의 분리단계가 단백질의 수율을 증가시키는데 가장 큰 영향을 미치는 것으로 판단되었다. 본 연구에서는 자연 침전방법을 통하여 실험하였는데 수율의 증가를 위해서는 원심분리와 같이 수용성 단백질의 양을 많이 얻을 수 있는 방법이 필요하고, 인지질이나 lipoprotein등의 성분의 제거효율을 높이기 위해서는 x-carrageenan등과 같은 natural gum성분의 첨가와 같은 방법이 필요하다. 그러므로 자연침전을 이용하여 수율의 증가측면과 비용의 절감의 효과를 얻을 수 있었다. 보다 효율적인 IgY의 분리를 위해서는 초기 단계에서 수율의 극대화와 불순성분 제거의 최대화가 동시에 요구되고 있다. 전처리 후의 시료를 이용하여 이온교환 크로마토그래피와 gel filtration chromatography를 통해 순도 90% 이상의 IgY를 얻을 수 있었다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.422-424
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• 2002

The accuracy of DXA(Dual Energy X-ray Absorptiometry) highly depends on the detection and separation capability of dual energy X-ray X-ray photons. In addition both of scan time and patient exposure are affected by detection efficiency. A CZT detector with a good energy resolution and high detection efficiency was evaluated for the application of bone densitometry. Its performance was compared to a photomultiplier tube with a NaI(T1) scintillator in terms of energy resolution, detection efficiency and the accuracy of bone mineral density measurement. The comparison study was performed with CZT detector and PM tube using DXA equipments(OSTEO Plus, OSTEO Prima, ISOL Technology). The energy spectrum was acquired using MCA(Multi-Channel Analyzer). The used X-ray energy ranged from 20keV to 86keV. The MCA result of the CZT detector showed a slightly sharper energy spectrum than that of NaI(T1). Detection efficiency of the CZT detector at 59.5keV was 1.4 times better. Remarkably the final results of bone mineral density measurements demonstrate only less than 1% difference. The CZT detector appears to have many benefits for the application of bone densitometry. Its excellent energy resolution can enhance the counting accuracy of dual energy X-ray spectrum. Furthermore its compactness in physical dimension and no cooling requirement will be additional benefits for a more compact and accurate bone densitometer.

• 한국컴퓨터정보학회논문지
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• 제10권2호
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• pp.49-57
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• 2005

본 논문은 상관관계(trade-off)에 의한 CLB구조의 CPLD 저전력 기술 매핑 알고리즘을 제안하였다. 제안한 저전력 기술 매핑 알고리즘은 주어진 불린 네트워크를 DAG로 구성하여 소모전력 계산을 위한 TD(Transition Density) 계산 단계와 매핑 가능 클러스터 생성, CLB 패킹의 단계로 구성하였다. TD 계산 단계는 DAG를 구성하고 있는 각 노드들에 대한 스위칭 동작을 계산하여 전체 소모 전력을 계산하는 단계이다. 매핑 가능 클러스터 생성 단계는 주어진 CPLD의 CLB에 대한 입출력의 수와 OR 텀수를 고려하여 매핑 가능 클러스터를 생성하는 단계이다. 매핑 가능 클러스터를 생성하기 위하여 공통 노드 클러스터 병합과 노드 분할, 노드 복제의 방법을 이용한다. 제안된 알고리즘을 SIS에서 제공되는 벤치마크에 적용하여 실험한 결과 OR 텀수를 5로 했을 경우 기존의 CPLD 기술 매핑 알고리즘인 TEMPLA에 비해 30.73$\%$의 소모전력이 감소되었으며, PLAmap에 비해 17.11$\%$감소되었다.

• 천문학회보
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• 제35권1호
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• pp.75.2-75.2
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• 2010

We investigate the dependence of occurrence of bar in galaxies on galaxy properties and environment. The environmental conditions considered include the large-scale background density and distance to the nearest neighbor galaxy. We use a volume-limited sample of 33,296 galaxies brighter than $M_r$=-19.5+5logh at $0.02{\leqq}z{\leqq}0.05489$, drawn from the Sloan Digital Sky Survey Data Release 7. We classify the galaxies into early and late types, and identify bars by visual inspection. We find that the fraction of barred galaxies ($f_{bar}$) is 18.2% on average in the case of late-type galaxies, and depends on both u-r color and central velocity dispersion $(\sigma);f_{bar}$ is a monotonically increasing function of u-r color, and has a maximum value at intermediate velocity dispersion (${\sigma}{\simeq}170km\;s^{-1}$). This trend suggests that bars are dominantly hosted by systems having intermediate-mass with no recent interaction or merger history. We also find that $f_{bar}$ does not directly depend on the large-scale background density as its dependence disappears when other physical parameters are fixed. We discover the bar fraction decreases as the separation to the nearest neighbor galaxy becomes smaller than 0.1 times the virial radius of the neighbor regardless of neighbor's morphology. These results imply that it is difficult for bars to be maintained during strong tidal interactions, and that the source for this phenomenon is gravitational and not hydrodynamical.

• 지역연구
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• 제8권1호
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• pp.31-50
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• 1992

The aim of this paper is to define major factors influencing land development of each of major uses (residential, commercial, industrial) in the process of rapid urban expansion. The main hypothesis of this study is that land use changing patterns are directed by supply side of land managed to public policies rather than demand side. The graphic analysis is applied to relationships between urban growth and land development process of each use and between land development project managed to public policies and land development process. Public and land development projects and zonning protection seem to be major roles of land supply and main determinants of urban spatial structure. Location factors for land development of each uses are selected in 23 variables. Factor analysis is applied to test correlation between variables in 1971 and 1981. Factor structure between two years is similar, but progressive processing of functional separation is derived such as intensive land use is grouped, different location between residential and industrial use is deep. Dependent variables are standardized to logarithm of land development of each use per unit vacant land in two periods, between 1971 and 1980 year and between 1981 year. Correlation analysis between 6 dependent variables and 23 location factors in each years are applied. Major factors of each use are selected in criteria such as high correlation with dependent variables, low correlation between independent variables and common application in two periods. As the result, major factors for residential land development are Land Readjustment Project (LRP), percent of total zoned area in residential zone, residential floor space density per available area, percent of total area in industrial use; for commercial development is distance to CBD, percent of total area in commercial use, residential floor space density per available area in each year, and volumn rate of industrial use; for industrial use is percent of total area of industrial use is percent of total area of industrial use, Industrial Estate Project (IES), LRP, and distance from CBD. Land development pattern of each use between two periods are slightly different. So 6 equation is derived from appling backward method of regession. Adjusted multiple R squares of all is more than 0.5 and those equation is statistically significant and valuable to assist urban land use forecasting.

• 상하수도학회지
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• 제27권2호
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• pp.261-272
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• 2013

Algae boom (Red tide) in south coastal area of Korea has been appeared several times during a decade. If algae boom appears in the desalination plant, media filter and UF filter are clogged quickly, and the plant should be shutdown. In general, Algae can be removed from water by flotation better than by sedimentation, because of the low density of algal cell. The purpose of this study conducts the CFD simulation of DAF flotation basin to apply the design of the dissolved air flotation with ball filter in the Test Bed for SWRO desalination plant. In this study, Eulerian-Eulerian multiphase model was applied to simulate the behavior of air bubbles and seawater. Density difference model and gravity were used. But de-sludge process and mass transfer between air bubbles and seawater were ignored. Main parameter is hydraulic loading rate which is varied from 20 m/hr to 27.5 m/hr. Geometry of flotation basin were changed to improve the DAF performance. According to the result of this study, the increase of hydraulic loading rate causes that the flow in the separation basin is widely affected and the concentration of air is increased. The flow pattern in the contact zone of flotation basin is greatly affected by the location of nozzle header. When the nozzle header was installed not the bottom of the contact zone but the above, the opportunity of contact between influent and recycle flow was increased.

• 한국인터넷방송통신학회논문지
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• 제16권2호
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• pp.63-70
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• 2016

본 논문은 위성 방송 시스템 표준안인 DVB-S3(Digital Video Broadcasting - Satellite)에서 전송률을 높이기 위해 제안되는 Nyquist rate 보다 빠르게 전송하는 FTN(Faster Than Nyquist) 기법과 LDPC(Low Density Parity Code) 부호간의 연접 부호기 구성 시, 인접 심볼간 간섭을 최소화하면서 전송률을 높이기 위한 효율적인 터보 등화 복호 방법을 제안한다. 본 논문에서는 기존의 FTN 복호 방식인 SIC(Successive Interference Cancellation) 기법을 이용한 복호 기법과 BCJR 등화기법에 관하여 소개하고, 두 기존 방식의 문제점을 해결하기 위한 새로운 기법을 제안한다. 본 논문에서는 FTN 신호를 복호하기 위해 LDPC 복호 신호를 분리된 외부 입력값을 BCJR 등화기와 연접하여 계산하여 반복 복호한다. 기존의 두 방식과 본 논문에서 제안하는 방식을 AWGN(Additive White Gausiian Noise) 채널 환경에서 시뮬레이션하여 성능을 비교한 결과, 기존의 방식과 비교하면 성능이 향상됨을 알 수 있다.

• 한국재료학회지
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• 제5권6호
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• pp.732-742
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• 1995

다이아몬드 증착시 기판의 표면처리를 변화시켰을 때 다이아몬드의 핵생성 밀도에 미치는 영향에 대하여 연구하였다. 실험장치는 열 필라멘트 CVD 장치를 사용하였고, 반응가스로 메탄과 수소가스를 사용하였다. 기판의 표면 처리는 탄소 상을 기판에 증착시키는 방법, Soot에 의한 기판 표면처리, 혹연에 의한 기판 표면처리로 크게 3가지로 행하였다. 모든 경우에 핵생성 밀도가 증가하였으나 탄소 상을 증착시킨 경우와 soot에 의한 사전처리의 경우의 핵생성 밀도의 증가가 혹연에 의한 처리보다 더 현저하였다. 또한 탄소강의 증착의 경우 표면에 굴곡이 없는 매우 평탄하고 균일한 다이아몬드 막을 얻을 수 있었다. 사전증착처리 한 기판에 탄소 층을 형성시켰을 때 탄소 층과 기판과의 접착력이 약한 것을 이용하여 다이아몬드 막을 쉽게 분리시켜 free standing 다이아몬드 박막을 얻을 수 있음을 알았다.