• Korean Journal of Community Nutrition
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• v.11 no.4
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• pp.534-540
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• 2006

Recent studies have shown that environmental, biochemical, nutritional or genetic factors affect bone mineral density (BMD). The purpose of the present study was to investigate the effect of vitamin D receptor (VDR) gentotype and nutritional status on BMD of elderly women living in a rural area. Three hundred thirty five elderly women over 65 years in Asan participated the study. Data for demographic and nutrient intakes were obtained by survey with a two day 24 hr recall method. BMD was measured by broadband ultrasound attenuation (BUA) using quantitative ultrasound (QUS). VDR genotypes of the subjects analyzed with Bsm I restriction enzyme were bb (92%), Bb (7%) and BB (1%). No differences were found between genotypes bb and Bb/BB in age, menopausal age, body mass index and body fat. BUA of bb genotype was higher (62.5 $\pm$ 15.6 dB/MHz) than Bb/BB genotype (56.1 $\pm$ 17.6 dB/MHz) by Student's t-tests. Correlation analyses showed strong negative correlation of BMD and age, but positive correlation with BMI, energy and calcium intake. When subgroup analyses were conducted after stratification by the median calcium intake level (412.9 mg/d), the above median calcium intake group showed significant difference in BUA by VDR genotype while the lower median calcium intake group did not show significant difference. The current study confirmed interaction of calcium intake and VDR genotype in association with BMD. Further nutritional intervention will be needed to improve calcium status of the elderly women living in rural areas.

• ALGAE
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• v.18 no.4
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• pp.273-280
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• 2003

The physico-chemical characteristics and seasonal variations of phytoplankton community were investigated in the Paksil and Jungyang marshes. Water and phytoplankton samples for analyses were collected monthly from April 2002 to March 2003. A total of 421 taxa of phytoplankton belonging to eight classes identified. The number of taxa was highest in Bacillariophyceae, followed by Chlorophyceae, Euglenophyceae, Cyanophyceae, Chrysophyceae, Dinophyceae, Xanthophyceae and Cryptophyceae. The standing crops ranged from 1.25 ${\times}$ $10^6$ to 5.85 ${\times}$ $10^6$ cells ${\cdot}l^{-1}$ in Paksil marsh and 0.25 to 9.63 ${\times}$ $10^6$ cells ${\cdot}l^{-1}$ in Jungyang marsh. The highest algal density at Paksil marsh was recorded in October during the high development of Chlorococcales while the lowest value occured in July. In the Jungyang marsh, the maximum algal density was recorded in October when Cryptomonas sp. and Mallomonas sp. accounted for 64% to total cell numbers and the lowest cell density was observed in January due to the decrease of Chlorophyceae. The dominant species were represented by Euglena proxima, Trachelomonas oblonga, Trachelomonas volvocina of Euglenophyceae, Dictyosphaerium pulchellum, Monoraphidium griffithii, Oocystis parva of Chlorophyceae, Dinobryon sertularia, Kephyrion rubri-claustri of Chrysophyceae, Achnanthes minutissima of Bacillariophyceae and Cryptomonas sp. of Cryptophyceae in the Paksil and Jungyang marshes. Phytoplankton diversity(H’) and dominance index varied rather irregularly throughout the sampling period but they were significantly correlated. The highest diversity(H’Paksil = 3.68, H’Jungyang = 3.63) coincided with the lowest values of dominance(DPaksil = 0.05, DJungyang = 0.05)

• Korean Journal of Human Ecology
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• v.23 no.4
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• pp.743-757
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• 2014

The purpose of this study was to compare nutrient intakes, blood lipids and bone density of male(n=69) and female(n=71) according to the obesity index by %Fat. The average energy intakes of obesity group was higher than normal group in male & female(p<0.001). The protein and fat intakes among three energy nutrients for male were higher than normal group(p<0.05~0.01), and carbohydrate intake of obesity group in female was higher than the other groups. TG, TC/HDL, blood glucose, blood pressure in male were higher than female(p<0.01~0.001), but HDL in male was lower than female. TC/HDL and diastolic blood pressure of obesity group were higher than normal group in male(p<0.05), but had not significant in female. Blood glucose in male was higher than female(p<0.001). T-score of forearm(=-1.26) and calcaneus(=0.42) for female were lower than male(=-0.63, 0.83), and T-score of calcaneus for obesity group(=1.03) in female was higher than normal group(=0.10). The T-score of forearm for obesity group in female was higher than the other group, but was not significant. These results suggest that ratio among three energy nutrients was kept balance for obesity group, especially, fat must be reduced in male than female, carbohydrate will be reduced in female than male to prevent obesity. Nutritional education for treatment obesity to prevent hyperlipidemia and arteriosclerosis is important for male too. T-score of forearm was lower than calcaneus in female, so exercise with arm than leg would be required to accumulate calcium in bone and to increase muscle to prevent osteoporosis.

• Nutrition Research and Practice
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• v.6 no.3
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• pp.195-200
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• 2012

The purpose of this study was to investigate the effects of ${\alpha}$-lipoic acid on body weight and lipid profiles in Sprague-Dawley rats fed a high fat diet (HFD). After 4 weeks of feeding, rats on the HFD were divided into three groups by randomized block design; the first group received the high-fat-diet (n = 10), and the second group received the HFD administered with 0.25% ${\alpha}$-lipoic acid (0.25LA), and the third group received the high-fat diet with 0.5% ${\alpha}$-lipoic acid (0.5LA). The high fat diet with ${\alpha}$-lipoic acid supplemented groups had significantly inhibited body weight gain, compared to that in the HFD group (P < 0.05). Organ weights of rats were also significantly reduced in liver, kidney, spleen, and visible fat tissues in rats supplemented with ${\alpha}$-lipoic acid (P < 0.05). Significant differences in plasma lipid profiles, such as total lipids, total cholesterol, triglycerides, low-density lipoprotein, and high-density lipoprotein, were observed between the HFD and 0.5LA groups. The atherogenic index and the plasma high density lipoprotein-cholesterol/total cholesterol ratio improved significantly with ${\alpha}$-lipoic acid supplementation in a dose-dependent manner (P < 0.05). Total hepatic cholesterol and total lipid concentration decreased significantly in high fat fed rats supplemented with ${\alpha}$-lipoic acid in a dose-dependent manner (P < 0.05), whereas liver triglyceride content was not affected. In conclusion, ${\alpha}$-lipoic acid supplementation had a positive effect on weight gain and plasma and liver lipid profiles in rats.

• Journal of Preventive Medicine and Public Health
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• v.53 no.5
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• pp.342-352
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• 2020

Objectives: The aim of this retrospective cohort study was to investigate whether non-alcoholic fatty liver disease (NAFLD) was associated with incident bone mineral density (BMD) decrease. Methods: This study included 4536 subjects with normal BMD at baseline. NAFLD was defined as the presence of fatty liver on abdominal ultrasonography without significant alcohol consumption or other causes. Decreased BMD was defined as a diagnosis of osteopenia, osteoporosis, or BMD below the expected range for the patient's age based on dual-energy X-ray absorptiometry. Cox proportional hazards models were used to estimate the hazard ratio of incident BMD decrease in subjects with or without NAFLD. Subgroup analyses were conducted according to the relevant factors. Results: Across 13 354 person-years of total follow-up, decreased BMD was observed in 606 subjects, corresponding to an incidence of 45.4 cases per 1000 person-years (median follow-up duration, 2.1 years). In the model adjusted for age and sex, the hazard ratio was 0.65 (95% confidence interval, 0.51 to 0.82), and statistical significance disappeared after adjustment for body mass index (BMI) and cardiometabolic factors. In the subgroup analyses, NAFLD was associated with a lower risk of incident BMD decrease in females even after adjustment for confounders. The direction of the effect of NAFLD on the risk of BMD decrease changed depending on BMI category and body fat percentage, although the impact was statistically insignificant. Conclusions: NAFLD had a significant protective effect on BMD in females. However, the effects may vary depending on BMI category or body fat percentage.

• Proceedings of the Korean Geotechical Society Conference
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• 2002.10a
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• pp.303-310
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• 2002

Overbreak occurred inevitably in a tunnel excavation, Is the main factor for increasing cost and time in tunnel projects. Furthermore the damage to the remained rock mass related to the overbreak can give rise to a serious safety problem in tunnels. As a rule of thumb, causes for the overbreak are inaccuracy in drilling, the wrong design of blasting and selection of explosives, and heterogeneity in rock mass. Specially, the geological features of the rock mass around periphery of an excavation are very important factors, so a lot of researches have been conducted to describe these phenomena. But the quantitative geological classification of the rock mass for the overbreak and the method for decreasing the amount of the overbreak have not been established. Besides, the technical improvement of the charge method is requested as explosives for the smooth blasting have not functioned efficiently. In this study, the working face around periphery of an excavation has been continuously sectionalized to 5∼6 parts, and the new Blastability Index for the overbreak based on 6 factors of RMD(Rock Mass Description), UCS(Uniaxial Compressive Strength) JPS(Joint Plane Spacing), JPO(Joint Plane Orientation), JPA(Joint Plane Aperture) and FM(Filling Material) is proposed to classify sections of the working face. On the basis of this classification, the distance between contour holes and the charging density are determined to minimize the overbreak. For controlling the charging density and improving the function of explosives, the New Deck Charge(N.D.C) method utilizing the deck charge method and detonation transmission in hole has been developed.

• Journal of the East Asian Society of Dietary Life
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• v.17 no.1
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• pp.1-10
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• 2007

The effects of mulberry-leaf powder Tofu(MPT) on anthropometric measurements, including bone mineral density(BMD) in the right carpus, biochemical bone turnover markers, serum levels of lipids and macrominerals, were investigated in 30 smoking male adults who lived in Choongnam were given MPT(100 g/day) for 4 weeks. The average ages, number of smoked cigarettes and packyear were 22.38 years, 15.12/day and 3.54 years, respectively. The nutrient contents per 100 g MPT were 86.10 kcal energy, 8.98 g protein, 0.53 mg fiber, 211.33 mg Ca and 1.59 g fat. Anthropometric measurements, including dietary intake using the 24-hours recall method, carpal BMD using DEXA, serum levels of protein, albumin and glucose, lipid profiles (cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol) with Al(atherosclerosis index), HTR, CRF, LHBt, some biomarkers of BMD(serum alkaline phosphatase activity, osteocalcin, urinary DPD), and serum macrominerals(Ca, Ca/P ratio, Mg) and Pb were analyzed before and after consumption of MPT. After MPT consumption, dietary intakes of plant protein, total Ca and plant Ca increased significantly, but there were no significant differences in anthropometric measurements, BMD with bone metabolism markers, serum levels of protein, albumin or glucose, lipid profiles with AI, HTR, LHR and CRF.

• Journal of Community Nutrition
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• v.2 no.2
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• pp.119-128
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• 2000

Lifestyle and dietary behavior intervention as the primary prevention of lipid disorder seems safe and compatible with other treatments of cardiovascular diseases. Cross-sectional associations between lifestyle factors and dietary behavioral factors with plasma lipid and lipoprotein levels were analyzed in 189 middle-aged men in Suwon, Korea. Overnight fasting plasma levels of total cholesterol, high-density lipoprotein(HDL)-cholesterol, triacylglycerol and glucose were analyzed. Blood pressure and anthropometric data were also measured. Lifestyle factors such as smoking status, alcohol consumption and frequency of physical exercise were evaluated by a self-administered questionnaire. Questions regarding dietary behavior were also asked. The subjects were 43.8%${\pm}$7.9 years old, and 23.8%${\pm}$2.6kg/m$^2$. From stepwise regression analyses, significant correlates with total cholesterol level were body mass index(BMI), alcohol intake(negative), age and coffee drinking(model R$^2$=14.3%). BMI, breakfast-skipping, age, and sleeping hours were significant for triacylglycerol level(model R$^2$=15.8%). BMI, alcohol drinking(negative), age, and coffee drinking were significant for low-density lipoprotein(LDL)(model R$^2$=11.7%). Age(negative), BMI(negative), alcohol drinking, stress level(negative), physical exercise, and cigarette smoking(negative) were significant for high-density lipoprotein(HDL)(model R$^2$=12.1%). From stepwise regression analyses, excluding BMI and age as factors in the model, alcohol intake(negative) and coffee drinking were significantly correlated with total cholesterol level(model R$^2$=4.4%) : breakfast-skipping with triacylglycerol(model R$^2$=3.2%) : alcohol intake (negative) with LDL level(model R$^2$=3.4%) : alcohol intake, physical exercise and stress level(negative) with HDL level(model R$^2$=6.3%). The findings suggest that a healthy daily lifestyle and dietary behavior may have an anti-atherogenic effect by altering plasma lipid and lipoprotein levels in middle-aged Korean men. (J Community Nutrition 2(2) : 119∼128, 2000)

• Journal of Korean Biological Nursing Science
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• v.19 no.4
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• pp.241-251
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• 2017

Purpose: This study aimed to examine the factors related to the bone mineral density (BMD) in male and female adults aged 50 years or older. The factors included were socio-demographics, body mass index (BMI), blood pressure, blood lipids, and health habits. Methods: As a secondary data analysis, this study used raw data from the 5th Korean National Health and Nutrition Examination Survey, and selected 2,295 adults aged over 50 years who participated in the survey and had BMD values. The T-score of the femoral neck was evaluated for BMD. Data were analyzed using descriptive statistics, ANOVA and multiple regression. Results: The factors influencing the BMD in men were age (${\beta}=-.029$, p<.001), BMI (${\beta}=.100$, p<.001), triglyceride (${\beta}=-.001$, p=.001), and calcium (${\beta}=.001$, p=.003), and the suggested regression equation explained 25.6% of the variance in BMD (F=16.32, p<.001). The factors related to BMD in women were age (${\beta}=-.060$, p<.001), BMI (${\beta}=.091$, p<.001), total cholesterol (${\beta}=-.002$, p=.028), HDL cholesterol (${\beta}=.009$, p=.001), and calcium (${\beta}=.001$, p=.004), and the suggested regression equation explained 47.0% of the variance in BMD (F=61.72, p<.001). Conclusion: Based on the findings of this study, the modifiable factors, such as BMI, blood cholesterol, and calcium, should be targeted to improve the BMD in both men and women.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.11 no.2
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• pp.32-39
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• 2005

Objectives To observe relationship between BMD(BMD; bone mineral density) and lipid metabolic indicator which consists of cholesterol, HDL(HDL; high density lipoprotein), Trigliceride which influenced by BMI(BMI; body mass index), BFR(body fat rate) indirectly and directly in both ways. Methods Among 120 old patients aging above 65 who admitted to Dep. of Oriental Rehabilitation, Jeon-Ju Oriental Medical Hospital, Won Kwang University in order to prevent demetia and CVA from Mar. 2004 to May 2005 correlationship between BMI, BFR, BMD etc. and lipid metabolic indicator was statistically analysed. Results BMD of male patient was higher than that of female patients and body weight, height, BFR, BMI was significantly related to BMD as well. Relationship between Total Cholesterol, HDL, Triglyceride and BMD was not significant. Conclusions From the above results, Relationship between Total Cholesterol, HDL, Triglyceride and BMD was not significant.