• The Korean Journal of Nuclear Medicine
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• v.1 no.1
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• pp.1-19
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• 1967

The effects of X-ray irradiation and the thyroid gland on the erythropoietic system were studied in the white male rabbits. The total body irradiation was done in doses of 250 r and 500 r to each of 5 rabbits for 10days. The factors were 220KV, 10mA, FLI/4 Cu+1 mmAI(HVL:2.0 mm Cu) 50 cm F.S.D. The thyroid dysfunction was experimentally induced, by giving 2mg of thyroid tablets per kg body weight for 15 days in 5 rabbits for hyperthyroidism and by giving 1.5 mC of $^{131}I$ per kg body weight in another 5 rabbits for hypothyroidism. Fourteen healthy rabbits were used as control. The hematologic changes and ferrokinetic data obtained from $^{59}Fe$ and apparent half survival of the red blood cells obtained from $^{51}Cr$ were compared. Following were the results: A. X-ray irradiated group; 1. There were no significant changes in hematologic findings except for leucopenia. A slight decrease of red blood cells was observed in 500 r irradiated animals. 2. The decreases in the iron turnover rates of the plasma and red blood cells as well as in the red cell renewal rate were found in both groups. A :significant decrease of the red cell iron utilization rate was observed in the 500 r irradiated animals. 3. The apparent half survival times of the red blood cells were slightly, in the 250 r ($12.1{\pm}0.80$ days), and markedly shortened in the 500 r irradiated animals ($9.8{\pm}1.38$ days), the normal being $14.0{\pm}1.6$ days. 4. It appears, therefore, that the anemia caused by X-ray irradiation is due to the inhibition of hemopoietic function and the excess destruction of the red blood cells. B. Thyroid dysfunction group; 1. The slight increases of the red blood cell count and circulating blood volume with the normal serum iron level were observed in the hyperthyroid group, while the decreases of the red and white blood cell counts, hemoglobin and hematocrit values with a marked decrease of the serum iron level in the hypothyroid group. 2. A marked decrease of the plasma iron disappearance rate with increases of plasma iron turnover, red cell iron utilization and red cell iron turnover were observed in the hyperthyroid group, while the marked delay and decreases in the hypothyroid group. 3. The apparent half survival times of the red blood cells were almost the same with the control in the hyperthyroid group, ($14.0{\pm}1.58$ while a marked shortening in the hypothyroid group $10.6{\pm}0.30$. 4. It was reconfirmed that the thyroid hormones bear a close relationship with the erythropoietic system, namely, the latter is stimulated by the former. The lack of the thyroid hormones thus induces the bone marrow depression leading to anemia the major cause of which, therefore, is not hemolysis.

• Journal of Preventive Medicine and Public Health
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• v.43 no.2
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• pp.109-116
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• 2010

Objectives: The pandemic of novel influenza A (H1N1) virus has required decision-makers to act in the face of the substantial uncertainties. In this study, we evaluated the potential impact of the pandemic response strategies in the Republic of Korea using a mathematical model. Methods: We developed a deterministic model of a pandemic (H1N1) 2009 in a structured population using the demographic data from the Korean population and the epidemiological feature of the pandemic (H1N1) 2009. To estimate the parameter values for the deterministic model, we used the available data from the previous studies on pandemic influenza. The pandemic response strategies of the Republic of Korea for novel influenza A (H1N1) virus such as school closure, mass vaccination (70% of population in 30 days), and a policy for anti-viral drug (treatment or prophylaxis) were applied to the deterministic model. Results: The effect of two-week school closure on the attack rate was low regardless of the timing of the intervention. The earlier vaccination showed the effect of greater delays in reaching the peak of outbreaks. When it was no vaccination, vaccination at initiation of outbreak, vaccination 90 days after the initiation of outbreak and vaccination at the epidemic peak point, the total number of clinical cases for 400 days were 20.8 million, 4.4 million, 4.7 million and 12.6 million, respectively. The pandemic response strategies of the Republic of Korea delayed the peak of outbreaks (about 40 days) and decreased the number of cumulative clinical cases (8 million). Conclusions: Rapid vaccination was the most important factor to control the spread of pandemic influenza, and the response strategies of the Republic of Korea were shown to delay the spread of pandemic influenza in this deterministic model.

• The KIPS Transactions:PartC
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• v.8C no.1
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• pp.60-67
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• 2001

Multicast Protocol for multimedia service on the Internet can be classified into two types, e.g., source based tree and shared tree according to difference of tree construction method. Shared tree based multicast is known to show outstanding results in the aspect of scalability than source based tree. Generally, There have been lots of researches on the method to satisfy QoS constraints through proper Rendezvous Point (RP) in the shared tree. In addition, as the multicast group members join and leave dynamically in the service time, RP of the shared tree should b be reselected for guranteeing Qos to new member, But, RP reselection method has not been considered generally as the solution to satisfy QoS C constraints. In this paper, new initial RP selection and RP reselection method are proposed, which utilize RTCP (Real Time Control Protocol) report packet fields. Proposed initial RP selection and RP reselection method use RTCP protocol which underlying multimedia application service So, the proposed method does not need any special process for collecting network information to calculate RP. New initial RP selection method s shows better performance than random and topology based one by 40-50% in simulation. Also, RP reselection method improves delay p performance by 50% after initial RP selection according to the member’s dynamicity.

• Radiation Oncology Journal
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• v.29 no.2
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• pp.83-90
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• 2011

Purpose: Flavopiridol enhanced radiation-induced apoptosis of cancer cells in our previous in vitro study. The purpose of this study was to assess if flavopiridol could enhance the radioresponse of mouse mammary tumors in vivo. Materials and Methods: Balb/c mice bearing EMT-6 murine mammary carcinoma were treated with flavopiridol only, radiation only, or both for 7 days. Flavopiridol was administered 2.5 mg/kg twice a day intraperitoneally (IP). Radiation was delivered at a 4 Gy/fraction at 24-h intervals for a total dose of 28 Gy. Tumor volume was measured and compared among the different treatment groups to evaluate the in vivo radiosensitizing effect of flavopiridol. Tumors were removed from the mice 20 days after treatment, and TUNEL and Immunohistochemical stainings were performed. Results: Significant tumor growth delay was observed in the radiation only and combined treatment groups, when compared with the control group. However, there was no significant difference between the tumor growth curves of the control and flavopiridol only group or between the radiation only and combination treatment group. Apoptotic cells of different treatment groups were detected by terminal deoxynucleotidyl transferase-medicated nick end labeling (TUNEL) staining. The expressions of Ku70 in tumor tissues from the different groups were analyzed by immunohistochemistry. Similarly, no significant difference was found between the apoptotic rate or Ku70 expression among the different treatment groups. Conclusion: Flavopiridol did not show evidence of enhancing the radioresponse of mouse mammary tumors in this study.

• Korean Journal of Food Science and Technology
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• v.31 no.1
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• pp.91-98
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• 1999

Plums (Prunus salicina L.) were coated with calcium-treated methylcellulose (CaMC) and hydroxypropylmethylcellulose-15 (CaHPMC-15). Respiration rate, weight loss, pH and titratable acidity, texture, and sensory characteristics were compared during 8-day storage period at $30^{\circ}C$. Weight loss and respiration rate of plums coated with CaMC and CaHPMC-15 were lower than those of control plums during storage while pH increased and titratable acidity slowly deceased during storage. Mechanical firmness was significantly deceased during storage, in which CaMC and CaHPMC-15-coated plums were harder than the control. Amount of soluble pectin, and pectin esterase and polygalacturonase activities as the markers of softening commonly increased with storage, but both CaMC and CaHPMC-15-coated plums were not found those increases. Sensory evaluation showed that the flesh softening of plums decreased during storage, and that in the coated plums exhibited the harder flesh. In conclusion, introduction of CaMC and CaHPMC-15 coatings on plums decreased respiration rate and contributed to delay of flesh softening, and the significant difference in postharvest storage quality of the both plums were not found between CaMC and CaHPMC-15 coatings.

• Horticultural Science & Technology
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• v.30 no.6
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• pp.718-724
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• 2012

Sugars play important roles in petal senescence of cut flowers. In the Expt. 1 of this study, the effects of different concentrations of glucose (60, 90, and $120g{\cdot}L^{-1}$) and sucrose (30, 60, and $90g{\cdot}L^{-1}$) application on the vase life, rate of flower diameter increase, rate of flower weight increase and ethylene production of cut tree peony (Paeonia suffruticosa 'Luoyang Hong') were evaluated. At the earlier stage, treatments of different concentrations of glucose and sucrose all retarded the process of flower opening and inhibited the increase of flower diameter and weight, while senescence of flowers fed with different concentrations of glucose was delayed at later stage. Flowers treated with $90g{\cdot}L^{-1}$ glucose displayed the longest vase life, which showed significant difference (P < 0.05) from those of flowers with the control and sucrose treatments. All treatments with glucose or sucrose not only retarded the decrease of flower diameter and weight, but also suppressed the ethylene production at the earlier stage and delayed the peak of ethylene evolution. In order to study the effect of exogenous sugar on the postharvest response of cut tree peony to ethylene, Expt. 2 was conducted. Cut flowers were treated with $90g{\cdot}L^{-1}$ glucose for 4 hours before (GE) or after (EG) exposed to $10{\mu}L{\cdot}L^{-1}$ ethylene for 4 hours. Generally, the opening process of flowers with GE and EG treatments was similar to that of the control, however GE treatment delayed flower senescence. Both GE and EG treatments improved flower diameter and weight, and GE treatment delayed the time of flower weight decrease. Besides, GE delayed climacteric ethylene evolution for 8 hours. All above suggest that exogenous sugars delay tree peony 'Luoyang Hong' cut flower senescence and extend flower vase life through their roles in the decrease of water loss and the suppression of sensitivity to ethylene and ethylene production.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.5
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• pp.1154-1163
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• 2008

DAS and SCADA system are main systems, which operate and manage the power system by using computer and communication technology. But DAS and SCADA have been operated independently in Korea, so there was some time delay in the fault handling and live-line work. To improve that problems, studies on the interface between DAS and SCADA have been needed. From November 2005 to December 2007, the pilot project has been performed in KEPCO's branch offices, as a result, direct method will be applied widely all over the country until 2010 because the operation information of substation users want can be transmitted fast and it is possible to control 43RC directly although the expense for direct method is about 1.3 times larger than that for web method. To improve problems revealed during the pilot project, substation object to object communication method is proposed and interface database automatic generation and interface system diagnosis and logging functions are developed. Interface data point and communication data type are defined, substation single line diagram automatic generation or manual editing function, SCADA monitoring and controlling function, log data managing function are developed in SCADA HMI program. It is expecting to reduce the average time for each outage about 33% and to improve the reliability, efficiency of operation, execution of DAS from automatic load transfer under a fault, and to contribute to export project.

• Journal of KIISE:Computer Systems and Theory
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• v.26 no.8
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• pp.984-998
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• 1999

최근 개인 휴대 통신에 대한 관심도가 증가하면서 B-ISDN (Broadband Integrated Services Digital Network)과 같은 기존의 유선 망에서 제공하던 다양한 멀티미디어 응용 지원을 무선 망으로 확장시키기 위한 연구가 활발히 진행되고 있다. 그러나 기존의 유선 망에서는 멀티미디어 응용 지원을 위해 QoS (Quality of Service) Provisioning에 관한 많은 연구가 되어 있으나 무선 망에서는 이동성과 무선 전파의 열악한 전송으로 인해 새로운 QoS Provisioning 방법에 관한 연구가 필수적이다. 본 논문에서는 이러한 무선 망의 특수성으로 인해 발생할 수 있는 서비스의 질 저하와 강제 종료를 줄임으로써 지속적인 QoS를 보장해 주고 한정된 무선 자원을 효율적으로 사용하며 처리에 의한 오버헤드를 줄이기 위하여 다음과 같은 세 가지 방법을 제안하였다. 첫째, 핸드오프 강제 종료율을 줄이기 위하여 대역폭 예약 방법을 사용하되 특정 셀의 트래픽 특성에 맞게 또한 시간대에 따른 트래픽 특성에 따라 예약 대역폭의 양을 조절하는 적응적 대역폭 예약 방법이다. 둘째, 많은 경우 각 셀의 트랙픽 변화는 일정한 주기로 변화한다는 특성에 따라 과거의 트래픽 정보를 이용하는 예측 기반의 대역폭 예약 방법이다. 마지막으로 호의 종류, 트래픽 특성, 단말기의 이동 속도에 따라 다른 우선 순위에 의해 호 수락 제어를 수행하는 우선 순위 기반의 호 수락 제어를 제안하였다. 시뮬레이션을 통하여 기존에 제안된 방법과 성능 비교하여, 요구되는 수준의 QoS 보장과 효율적인 자원의 사용, 요구되는 처리비용의 최소화를 통해 전체 시스템의 성능 향상을 입증하였다.Abstract As interest in wireless hand-held terminals and in personal communications services increases recently, there have been broad studies on the ways to support multimedia applications provided in wired networks such as B-ISDN (Broadband Integrated Services Digital Network) in wireless networks. However, since many studies have focused on Quality of Service (QoS) Provisioning in wired networks to provide multimedia applications, new methods of QoS Provisioning are needed in wireless networks to resolve the problem of wireless channel fading and the difficulty of mobility occurred in wireless networks. This paper proposes three schemes of QoS Provisioning in wireless networks which will make continuous QoS guarantee and efficient use of limited wireless resources possible. The first scheme reserves bandwidth in proportion to the amount of real-time traffic in the neighbor cells to decrease the handoff dropping rate of delay sensitive real-time connections, adapting reserved bandwidth for efficient resource utilization. The second scheme is predictive bandwidth reservation scheme that utilizes the past handoff information. It can decrease overheads required to adapt bandwidth reservation. The last scheme is priority-based call admission control prioritizing traffic type (real-time traffic/ non-real-time traffic), connection type (new connection /handoff connection), and mobile terminal speed (fast mobile/slow mobile). Simulation results show that the proposed QoS Provisioning schemes improve the total system performance by achieving three goals - required QoS guarantee, higher bandwidth utilization and less overhead.

• Journal of the Institute of Electronics and Information Engineers
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• v.51 no.3
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• pp.89-101
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• 2014

Recently, as domestic air traffic dramatically increases, the need of ATC(air traffic control) systems has grown for safe and efficient ATM(air traffic management). Especially, for smooth ATC, it is far more important that performance of display system which should show all air traffic situation in FIR(Flight Information Region) without additional latency is guaranteed. In this paper, we design a ASTERIX(All purpose STructured Eurocontrol suRveillance Information eXchange) parsing module to promote stable ATC by minimizing system loads, which is connected with reducing overheads arisen when we parse ASTERIX message. Our ASTERIX parsing module based on pattern matching creates patterns by analyzing received ASTERIX data, and handles following received ASTERIX data using pre-defined procedure through patterns. This module minimizes display errors by rapidly extracting only necessary information for display different from existing parsing module containing unnecessary parsing procedure. Therefore, this designed module is to enable controllers to operate stable ATC. The comparison with existing general bit level ASTERIX parsing module shows that ASTERIX parsing module based on pattern matching has shorter processing delay, higher throughput, and lower CPU usage.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.43 no.3 s.345
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• pp.118-125
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• 2006

Mobile nodes in FHMIPv6 has both advantages of HMIPv6 protocol which reduces signaling delay time and resource consumption during a handover and fast handover algorithm which reduces packet loss. Fast handover algorithm can reduce packet loss by 'tunneling' method ; that transmits a packet from old access router to new access router in case of handover. However, the fast handover algorithm can cause a reordering problem in a receiver between packets tunneled from the previous access router and packets transmitted directly to the new access router, which could degrade the TCP performance due to congestion control. In this paper, we propose two algorithms to solve the reordering problem in fast handover. The first one uses a holding timer for tunneling, the other adds a new algorithm to routers that adopt snoop protocol. We compare the performance of the proposed reseuquencing algorithms with that of the existing FHMIPv6 protocol by simulation. The simulation results show that the proposed algorithms solve the reordering problems and enhance TCP performance by preventing TCP sender entering congestion control.