• Animal cells and systems
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• v.16 no.4
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• pp.295-301
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• 2012

Interdigital tissue regression is one of the most well-known examples of embryonic programmed cell death, providing the mechanism behind separation of developing digits. Caspases have been shown to play a key part in this process, with activated caspase-3 localized between the developing digits. In caspase-3 knock-out adult mice, however, the digits are completely separated with no webbing. In other mutants with defects in the apoptotic machinery, such as Apaf1 deficient mice, interdigital tissue regression is initially inhibited but the webbing eventually disappears as alternative/additional cell death mechanisms step in. In order to investigate whether a similar temporal effect occurs after loss of caspase-3, we have used an in vitro approach to inhibit caspase-3 at specific times during digit separation. Previous limb explant culture approaches have encountered problems with proper limb development in culture, and thus a modified technique was used. The new approach enables detailed observation of the effects of caspase-3 inhibition on interdigital regression. Using these methods, we show that caspase-3 inhibition caused a delay in the loss of interdigital tissue compared with control explants, similar to that observed in Apaf1 mutant mice. Along with immunohistochemistry, active caspase-3 positive cells of the interdigital vs. digital regions were measured by flow cytometry. Notably, activated caspase-3 in vivo was found not only in the interdigital mesenchyme but also in the TUNEL negative digit region, supporting a role for caspase-3 in nonapoptotic events.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.27 no.2
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• pp.261-271
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• 2009

Due to the recent rise of a need for 3 dimensional geospatial information on urban areas, general interest in aerial multi-view cameras has been on an increase. The conventional geospatial information system depends solely upon vertical images, while the multi-view camera is capable of taking both vertical and oblique images taken from multiple directions, thus making it easier for the user to interpret the object. Through our research we developed a prototype of a multi-view camera system that includes a camera system, GPS/INS, a flight management system, and a control system. We also studied and experimented with the camera viewing angles, the synchronization of image capture, the exposure delay, the data storage that must be considered for the development of the multi-view camera system.

• The Journal of the Korean bone and joint tumor society
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• v.4 no.1
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• pp.30-36
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• 1998

Squamous cell carcinoma is a neglected disease entity in orthopedic oncology. The purpose of this study was to analyze overall survival and the role of surgery on survival and to evaluate the significance of possible prognostic factors. From Oct, 1986 to Aug, 1996, 57 patients were enlisted and 42 patients ere eligible. Inclusion criteria included more than one year follow-up and no distant metastasis at the first visit. Staging and survival followed AJC classification and Kaplan-Meier plot. Stage II included 17 cases and stage III, 25 cases. Thirty-eight patients underwent operations, chemotherapy, and/or radiotherapy, and the remaining four had operations only. The chemotherapeutic regimen was adriamycin-cisplatin. The average follow-up period was 45 months. The ten-year actuarial survival rate of whole patients was 65.4%. Location of primary lesion, stage, pathologic grading, and intensity of chemotherapy in the same stage showed a significant difference in survival. Nine out of 42 patients had local recurrence. Seven patients had inadequate wide margins and two had intralesional margins. Average period of recurrence from operation was 13(4-35)months. The operation itself had no impact on survival but a surgical margin of no less than 3cm from the lesion was important for local control. Pathological grade and staging were significant variables for long term survival. Acral lesion had a significantly higher chance of regional and distant metastasis but actual survival showed no difference. In stage II, aggressive chemotherapy could delay or reduce the chance of regional or distant metastasis.

• Korean Journal of Construction Engineering and Management
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• v.14 no.3
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• pp.12-21
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• 2013

Total Project Cost Management System(TPCMS) was introduced with the purpose of increasing the efficiency of cost control for public construction project in 1994. In this paper, general perception of participants of the public construction project on the TPCMS was examined, and the problems in implementing the TPCMS was figured out through expert interviews and survey. Then better ways to implement the system were drawn based on the problems. To effectively manage the cost of public construction project, basically project cost should be estimated accurately in planning stage and managed based on it to have a project complete within the budget. In addition, the cost need to be managed in more systematic ways in terms of data collection and analysis, and the autonomy in managing the project cost given to the project owner needs to be expanded. Most of all, proper budget should be provided to prevent a project from delay through setting the priority of projects and proper budget allocation based on the priority.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.11A
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• pp.1059-1067
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• 2006

AODV(Ad-hoc On-demand Distance Vector) routing protocol was devised for use of mobile nodes in Ad-hoc network. When we use the AODV routing protocol in Ad-hoc networks with high mobility, disturbance of optimized route path and link break occur. In order to solve the shortcomings, this paper proposes a new routing protocol in which new routing control messages are added to the existing AODV. The proposed protocol minimizes link break and transmission delay while is able to secure the optimized route path constantly in changes of network topology The performance of the proposed routing protocol was evaluated by using us2 network simulator. The actual Ad-hoc network test bed provides us the most reliable experimental data for Ad-hoc networks. In order to support this experimental environment, the dissertation also developed an efficient embedded system on which AODV routing protocol, NAT, Netfilter can run and other event message can be verified without declining efficiency. The correct operation of AODV routing protocol has been verified in both the Ad-hoc network test bed in which the embedded system was used, and Ad-hoc networks linked with Ethernet backbone network.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.33 no.12B
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• pp.1058-1065
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• 2008

In the Internet, as computer resource is developed, multimedia data request being increase more and more. It is effective way that process both high capacity-data and real-time data. Overlay Multicast is an effective method for efficient utilization of system resources and network bandwidth without using hardware customization. Overlay Multicast is an effective method for multimedia data service to multi-users. Multicast tree reconstruction is required when a non-leaf host leaves or fails. In this paper, relay-frame interval is selected as revealed network-state with jitter. In our proposal, multi-user service control algorithm gives a delay effect in multimedia request time. The simulation results show that our proposal takes shorter period of time than the other algorithms to reconstruct a similar tree and that it is a more effective way to deal with a lot of nodes that have lost their multi-user nodes.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.971-974
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• 2005

Science and technology-related societies in the interior of a country sum up to approximately 660, and are increasing yearly, due to the development of new research fields and segmentation of past studies. Such societies are contributed with latest academic research information, and the submitted studies go through an review process before publication. A majority of the societies employ the traditional off-line review method; various problems and issues occur in delay of submission, review, revision, and management of the numerous paper submitted and published. Therefore, this study suggests the design of, and implemented an on-line paper review system which processes on-line submission and review of paper, facilitates swift and review progress, and enables efficient control and management on general tasks and academic information through integrated administration of members and published works.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.2 no.1
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• pp.45-51
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• 1998

In the realization of a high speed digital transmission over several tens kbps in mobile communications, it follow delay distortion on a count of transmission path variation by multipath interference waves. Therefore it is inevitably necessary to establish the techniques overcoming the frequency selective fading. In this paper, a feedback running RLS algorithm which is improved the RLS algorithm using exponential weighting factor, is proposed for the control algorithm of DFE and by the computer simulation method, and the performance characteristics of DFE is analyzed for the one-ray and two-ray waves model under the random Gaussian noise. The computer simulation results of proposed RLS algorithm for the $\pi$/4QPSK signal with one symbol time delayed interference signal of S/I = 20［dB］, under the S/N = 10［dB］ with $\lambda$= 0.9 showed excellent following characteristics and equalization characteristics.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.8 no.6
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• pp.1458-1464
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• 2007

Today, domestic and foreign manufacturing industries have to cope with obsolescence of manufacturing equipment because the shifting market trends drive the rapid changes in the production process resulting in stressful operation. Quality control process for manufacturing and production involves a familiar step - when the production process is completed, every item is subjected to various routine tests to determine that it meets the minimum quality standards. Typically, when a faulty product is found, the production line has to be stopped and the current batch is marked for further inspected and exhaustive testing. In this research, we propose a quality monitoring system for productivity enhancement. Our approach aims to reduces the operational down time in the production line of a car-component factory. The proposed monitoring system for productivity enhancement is designed to collect the data through testing at each phase of the assembly line and uses predictive methods on the collected data to achieve early detection of faults in the production process and minimize the number of products in a faulty batch thus minimizing the losses incurred from defective products. More importantly, this system aims to forecast and proactively detect faults and activate warnings when they are detected thus minimizing items in the defective batch, reducing the damage to manufacturing equipment and ultimately reducing the operational downtime or the delay in the resumption of normal factory operation.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.41 no.10
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• pp.1210-1220
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• 2016

As modern warfare has changed into network centered, the ability to share situational awareness among allies become a core competency for performing operational missions. In an airborne environment, it uses a tactical data link such as Link-16 for shared situational awareness. There exist problems when it shares situational awareness over the existing data link that can not allocate slots dynamically or that can not change the number of a slot to be allocated. In addition, there was a problem that can not share this failure so that failed to improves situation awareness because of finite time slot resources. In this paper, we accommodate dynamic slot allocation and changes of slot allocation with mixed structure of TDMA (time division multiple access) and random access. We propose a technique that can be used when available slots are exhausted, and a load balancing method to prevent slot allocation delay when slot requesting or message sending is concentrated on a single subframe.