• Korean Journal of Acupuncture
• /
• v.24 no.4
• /
• pp.111-129
• /
• 2007

Objectives & Methods : The purpose of this study is to observe the effects of Coicis Semen Herbal-acupuncture solution (CS-HAS) at the Joksamni (ST36) on the collagen-induced arthritis in the DBA/1J mouse. The author performed several experiments to analyze the effects of CS-HAS on arthritis; change of the weight; the spleen size and adhesion rate; serum cytokine levels; serum antibody levels; changes of immunocyte counts; the histological changes of joint. Results : In the Coicis Semen Herbal-acupuncture (CS-HA), arthritis index, the incidence of arthritis, and the degree of joint edema were decreased. In CS-HA, there was no weight loss. The size of the spleen, adhesion rate, and the edema and transformation of joint were lowered. In CS-HA, the levels of IL-1${\beta}$, IL-6, TNF-${\alpha}$, IFN-${\gamma}$, IgG, IgM, and anti-collagen II in serum and the levels of IFN-${\gamma}$, IL-4, IL-10 in spleen were significantly decreased. In CS-HA, the expression ratios of $CD45^+$ to $CD3e^+$ and $CD8^+$ to $CD4^+$ were decreased. Also, the overall $CD4^+/CD8^+$ cell ratio was lowered in spleen. Ratios of the $CD4^+/CD25^+$, $CD45^+/CD69^+$ cells were decreased in lymph nodes. In addition, ratios of the $CD3^+/CD69^+$, $CD11b^+/Gr-1^+$ cells were also decreased in synovium. In the histological study, the cartilage destruction and synovial cell proliferation, and collagen fiber destruction were decreased with CS-HA treated group. Conclusions : From the results mentioned above, it is suggested that CS-HA at the ST36 has several significant effects on the collagen-induced arthritis.

• Restorative Dentistry and Endodontics
• /
• v.22 no.1
• /
• pp.93-109
• /
• 1997

Finding a right repair material for furcation perforation is one of the major issues in clinical endodontics. In this experiment, three materials, calcium sulfate, amalgam, and calcium hydroxide were tested for perforated furcation repair. Sixty premolars and molars of five dogs were used. A #4 round bur was used to create the perforation. All experimental teeth were divided into two repair-time groups. One was immediate-repair group, where the perforation was repaired immediately, the other was delayed-repair group, where the perforation was left open for four weeks and then repaired with the same manner as in the immediate-repiar group. All chamber openings were sealed with amalgam and then radiographed. The animals were sacrificed at eighth week following the repair procedure. Radiographic evaluation for furcal bone destruction was done. Histologic evaluation was ranked as 0,1,2,3 according to the inflammation degrees. New bone formation was also recorded. The following conclusions were drawn within the limits of the experimental results: 1. In immediate-repair group, no significant differences existed between the materials. 2. In delayed-repair group, calcium sulfate showed significantly less furcal bone destruction and lower inflammation degree than amalgam.(p<0.05) 3. Overextruded specimens showed more severe inflammation than unextruded specimens. 4. Most of the specimens showed certain degrees of inflammatory reaction and incomplete hard tissue healing. 5. In delayed-repair group, treated group showed less inflammation than untreated control group.

• Korean Journal of Agricultural Science
• /
• v.16 no.1
• /
• pp.102-110
• /
• 1989

Surface structure and X-ray diffractogram of gelatinized potato starch on heating temperature, time and additives were investigated by Scanning Electron Microscopy (SEM) and X-ray diffractometry. The results obtained are as follows; Potato starch had an amylose content of 23.5%, and blue value of 0.41. Raw potato starch granuls showed egg form. Destruction of starch granuls increased as gelatinizing time and temperature increased. The degree of gelatinization of potato starch showed to be 90% by X-ray diffractomertry at $70^{\circ}C$. There were no significant differences in degree of gelatinization of potato starch on gelatinizing time and phosphate concentration at $70^{\circ}C$. The degree of gelatinization of sample prepared was higher in presence of phosphate than in absence of phosphate.

• Journal of Fisheries and Marine Sciences Education
• /
• v.17 no.1
• /
• pp.1-17
• /
• 2005

The purpose of this study is to prepare the way for the prevention and improvement of the ocean environment pollution and destruction by researching and analyzing the degree of interests in the ocean environment which the students of seaside vocational high schools have. The concerns of this study are as follows: 1. The vocational high school students in the seaside cities of Busan and Pohang have recognized that the ocean is the object of the highest potential of development and that through the degree of their recognition that they should better preserve the ocean environment prior to a high degree of local seaside development. 2. Although they have recognized that the ocean environment has a great influence on the life of people, their interests in the environment is low. Also, it is shown that they get their knowledge and information through TV. 3. They've understood that the main factor of ocean contamination concerns the home and the causes of ocean contamination are sewage and waste material from daily life. Moreover, their answers reveal that they believe that they should participate in a sanitization activity for the ocean environment voluntarily and put trash into nearby trash cans as opposed to inconsiderately throwing away trash on the beach. 4. Their answers also show that they recognize the elements that can best preserve the ocean environment start at home and with government, and school services through experience activities are the most effective for the education of the ocean environment.

• The Journal of Internal Korean Medicine
• /
• v.26 no.2
• /
• pp.320-332
• /
• 2005

Objectives: The aim of the experiment is to identify any anti-tumor effects of Duchesnea indica(Andr.) Focke on stomach, liver, urinary bladder, prostate and kidney cancer cells. Materials & Methods: For cancer cells, AGS stomach, Hep3B and Hep3G2 liver, HT-1197, HT-1376 urinary bladder, PC3 prostate, and A-704 kidney cancer cells, all obtained from Korean Ce 11 Line Bank, were used. The boiled extract of Duchesnea indica(Andr.) Focke (10 and 20 microliters) was injected into cultures, and the cultures were observed at 0, 6 and 12 hours, and from then on at 12 hours intervals up to 72 hours. The destruction of stomach, liver, urinary bladder, prostate and kidney cancer cells were measured through Trypan blue exclusion testing. The suppresion on viability of stomach, liver, urinary bladder, prostate and kidney cancer cells was measured via MTT assay. Anti-cancer mechanisms were assessed by analyzing the cell cycle. Results: In morphologic change, AGS, Hep3B, HepG2 showed the withdrawn and floating appearance that is typical in cellular impairment. The destruction of AGS, HT-1197, HT-1376, A-704, PC-3, Hep3B and HepG2 cancer cells in each test group was greater than that in the control group to a statistically significant degree. The suppression on viability of AGS, HT-1197 and Hep3G in each test group was greater than that in the control group to a statistically significant degree. Analysis of the cell cycle after injection of D... Focke showed inhibition of cell division in all test groups(AGS, Hep3B, HepG2, HT-1197, HT-1376, PC3, A-704). Conclusions: The results of this experiment suggest that Duchesnea indica(Andr.) Focke has statistically significant anti-tumor effects on stomach, urinary bladder, kidney, prostate and liver cancer, of which stomach and liver cancer are prominently significant. This in vitro experiment supports a role for Duchesnea indica(Andr.) Focke as a potential cancer treatment, but progressive research on Duchesnea indica(Andr.) Focke and its anti-tumor effects is needed to develop a practical application for it in cancer treatment.

• Korean Journal of Environment and Ecology
• /
• v.7 no.1
• /
• pp.22-28
• /
• 1993

Recently, by fast industralization and development without environmental concern, our environment deterioration have being continued rapidly. Therefore, many species is placed on crisis of extinction or was already extincted by habitat destruction. In Minjujisan area, there is a plan to construct the Sport and Leisure Complex by which convert the forest conservancy district to the district of development promotion and district of sighseeing and leisure by Yongdong District. To investigate the avifauna impacts by habitat destruction, bird censuses was carried out before the Sport and Leisure Complex be construct in Minjujisan and Sokgisan area during 4-5 May, 1992 and 16-21 June, 1992. Total 229 birds of 41 species in 23 family of 9 orders were recorded during censuses. Sitta europaea amurensis was the most abundant species and Parus ater amurensis, Phylloscopus borealis xanthodryas, Parus major wladiwostokensis, Parus palustris hellmayri, and Turdus pallidus were dominant species. Accipiter nisus nisosimilis, Accipiter soloenis, and Otus scops stictonotus were found out to the natural monuments in this suvey. Halcyon pileate was observed to a rare bird in this surveyed area. Species diversity of this census was 3.381 which showed slightly higher degree than other surveyed area. The area of Minjujisan, Sokgipong, and Samdopong which have little pollution agent around there and kept away from mankind were approved the heavy avifauna area which have so many bird species. Biogeographically, the Taebaek Mountains was connected with the Sobaek Mountains through this area, therefore it was significant that many animal species could be move to each mountains ranges. The construction plan of the Sport and Leisure Complex in Minjujisan area should be restrain with concern about environmentally destruction by the Muju Resort in Dokyusan National Park which connected to that area have master plan to development the ski slopes for the 1997 Universiad with permission by the Ministry of Environment.

• Korean Security Journal
• /
• no.37
• /
• pp.325-354
• /
• 2013

The concept of national security and the fundamental system for crisis management have departed from traditional methods and the importance of a national critical infrastructure crisis management has been emphasized. A national critical infrastructure crisis means a situation where human resource, material and functional system that may have a material effect on the critical functions of the government, the vitality and integrity of society, national economy and the safety of the public becomes disabled due to causes such as terrorism or major disasters. Although North Korea had been subject to numerous rounds of negotiations and sanctions as it continually developed nuclear weapons since the 1960s, it has also showed off its nuclear armaments through successful nuclear testings and missile launches. As the development and threat of North Korea's weapons of mass destruction becomes more noticeable and the range of its risk expands, this study focuses on the potential for an absence of leadership for national crisis management where the country's leadership, which should serve the critical role and function of handling national crises, becomes completely destroyed by the unexpected initial attacks by North Korea. As a result, the purpose of this study is to propose safety measures for the country's leadership in preparation for North Korea's threat of nuclear weapons by examining the concept and degree of risk of weapons of mass destruction with a focus on nuclear weapons, analyzing the substance of the threat of North Korean nuclear weapons and evaluating such threat. In conclusion, first, to ensure the normal functioning of a national crisis management system in the event of a national crisis, we must seek safety measures that conform to the scope and succession order of the leadership of the national crisis management for an Enduring Constitutional Government (ECG) and the Continuity Of Operations (COOP). Second, in the event of a national ceremony, the gathering of the country's leadership all together in an open place should be avoided. In unavoidable circumstances, the next in rank that will act on behalf of the current leader should be designated and relevant safety measures should be taken. Third, during time of peace, in preparation for national crises, the scope of protection for the country's leadership should be prescribed and specific security and safety measures should be implemented. Fourth, the succession order for acting president in the case of the death of the president pursuant to Articles 71 and 26(1) of the National Government Organization Act should reconsidered to see whether it is a reasonable provision that takes into consideration a national crisis management that corresponds to the threat of North Korean nuclear weapons and weapons of mass destruction. Pursuant to the Basic Guidelines for National Crisis Management set out under Presidential Directive No. 229, the Korean government is currently operating a case-by-case "crisis management standard manual" and its sub-manuals and has also prepared the Presidential Security Service's security and safety measure regulations regarding the acting president. Therefore, the Korean government should actualize the above points in the case-by-case crisis management standard manual and security and safety measure regulations regarding the acting president to implement and legislate them.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1979.05a
• /
• pp.4.4-5
• /
• 1979

The degree of hearing impairment of chronic otitis media will indicate the nature and severity of middle ear pathology especially condition of ossicular chain, size of ear drum perforation and location of granulation tissue in the middle ear cavity. The subjects were 189 ears of tympanoplasty for chronic otitis media and divided into four groups as follows: Normal ossicular chain with only ear drum perforation (group I), normal ossicular chain with granulation tissue only around the ossicles regardless of any other region (group II), ossicular ankylosis or fixation of handle of malleus to promontory with or without granulation tissue around the ossicle (group III) and ossicular interruption by partial or complete destruction(groupf IV). The results were concluded as follows: 1) The average hearing threshold of chronic otitis media was 44.6 dB and hearing threshold was closely related to the condition of ossicular chain. Hearing threshold became greater in order of normal ossicular chain, ankylosis and interruption. 2) The average hearing threshold of ossicular interrupted group was 49.1 dB and it was greater in the cases of total destruction than that of partial destruction. 3) The hearing loss in the cases of normal ossicular chain with only tympanic membrane perforation was within 45 dB and this level was presumed to represent normal ossicular function. The degree of hearing loss was in proportion to the size of ear drum perforation and when over 45 dB, other middle ear pathology was suggested. 4) In the cases of small ear drum perforation with normal ossicular function, the hearing threshold was within 30 dB. 5) In the type of audiogram, flat type was 30.2% and ascending type 35.4%. Descending type was more frequent in the cases of normal ossicular mobility with granulation tissue around the ossicle and flat type was observed frequently in the cases of ossicular ankylosis. 6) Carhart's notch was seen in 14 cases (7.4%) and observed mainly in ossicular ankylosis. 7) There was no relation between hearing threshold and histopathological type of granulation tissue in chronic otitis media. However the degree of hearing impairment was related to the location of granulation tissue in the middle ear cavity. 8) Authors recognized the granulation tissue compensated the function of interrupted ossicular chain.

• Korean Journal of Fisheries and Aquatic Sciences
• /
• v.44 no.4
• /
• pp.383-389
• /
• 2011

The negative fishery factors from an environmental perspective are greenhouse gas emissions due to high fossil fuel use, destruction of underwater ecosystems by bottom trawls, a reduction in resources by fishing, and damage to ecosystem diversity. In particular, the greenhouse gas emissions from fisheries is an important issue based on the Cancun meeting in Mexico in 1992 and the Kyoto protocol in 2005. However, no investigations on the GHG emissions from Korean fisheries have been conducted. Therefore, a quantitative analysis of GHG emissions from the Korean fishery industry is needed as a first step to identify a method to reduce GHG emissions from fisheries. The purpose of this study was to investigate the degree of GHG emitted from fisheries. Here, we calculated the GHG emissions from four main Korean fisheries(i.e., large trawls, large purse seines, Danish seines, and bottom pair trawls) using the life cycle assessment(LCA) method. The system boundary and input parameters for each process level were defined for LCA analysis. The fuel use coefficient of each fishery was also calculated. The GHG emissions from edible seafood were calculated considering different consuming areas. The results will be helpful to understand GHG emissions from Korean fisheries.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.29 no.2
• /
• pp.180-186
• /
• 2016

Anal and perianal condyloma acuminatum(CA), which is a large cauliflower-like tumor, is a manifestation of human papillomavirus (HPV) infection. HPV may be acquired via sexual transmission, vertical transmission or nonsexual contact. It is an uncommon condition in children but the incidence in children has been increasing recently. There are many therapies for CA including chemical or physical destruction, immunological therapy, or a surgical excision. All these procedures have some degree of limitations such as limited clearance rate, high recurrence rate, pain, bleeding, release of potentially infectious aerosols and scar. It may be traumatic mentally to the children as well as physically. Korean Medicine included herbal treatment and herbal ointment for CA is no pain, and it doesn't need an anesthesia. We present a case of anal and perianal CA in a 2 years old boy that was treated successfully with Korean Medicine, with no recurrence during the follow up 3 months.