• Journal of Haehwa Medicine
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• v.18 no.1
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• pp.67-81
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• 2009

1. According to causes of attack and symptoms, tinnitus is divided into two categories; deficiency and excess. Causes of excess syndrome of tinnitus were wind fire in the liver and gallbladder, phlegm fire, blood stagnation, and heat in meridian system and the causes of deficiency syndrome of tinnitus were qi deficiency or blood deficiency after an illness or delivery, yin deficiency of liver and kidney, and deficiency of sea of the marrow. 2. Tinnitus was related to the vicera and bowels, especially to liver, gallbladder and urinary bladder. 3. In regard of method of treatment, tonify kidney, nourish heart, clear the liver and discharge heat are used according to visera and bowel theory. Clear phlegm and downbear fire are used for phlegm fire. Tonify spleen and kidney is used for ancestral vessel deficiency. Dispel wind and dissipate fire can be used according to theory of five elements' motion and six kinds of natural factors. 4. The basal meridian of acupuncture and moxibustion treatment were the channels of Shaoyang.. 5. Regarding neuropsychiatric aspect of tinnitus, sudden anger and depression of mind were the main mechanism of disease and liver fire was the main cause. The prescriptions for neuropsychiatric tinnitus were Dangguiyonghuehwan, and Yongdamsagantang.

• Asian Spine Journal
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• v.12 no.6
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• pp.1127-1145
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• 2018

Several theories have been proposed to explain the etiology of adolescent idiopathic scoliosis (AIS) until present. However, limited data are available regarding the impact of vitamin D insufficiency or deficiency on scoliosis. Previous studies have shown that vitamin D deficiency and insufficiency are prevalent in adolescents, including AIS patients. A series of studies conducted in Hong Kong have shown that as many as 30% of these patients have osteopenia. The 25-hydroxyvitamin D3 level has been found to positively correlate with bone mineral density (BMD) in healthy adolescents and negatively with Cobb angle in AIS patients; therefore, vitamin D deficiency is believed to play a role in AIS pathogenesis. This study attempts to review the relevant literature on AIS etiology to examine the association of vitamin D and various current theories. Our review suggested that vitamin D deficiency is associated with several current etiological theories of AIS. We postulate that vitamin D deficiency and/or insufficiency affects AIS development by its effect on the regulation of fibrosis, postural control, and BMD. Subclinical deficiency of vitamin K2, a fat-soluble vitamin, is also prevalent in adolescents; therefore, it is possible that the high prevalence of vitamin D deficiency is related to decreased fat intake. Further studies are required to elucidate the possible role of vitamin D in the pathogenesis and clinical management of AIS.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.22 no.1
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• pp.15-20
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• 2022

The most common urea cycle disorder is ornithine transcarbamylase deficiency. More than 80 percent of patients with symptomatic ornithine transcarbamylase deficiency are late-onset, which can present various phenotypes from infancy to adulthood. With no regards to the severity of the disease, characteristic fluctuating courses due to hyperammonemia may develop unexpectedly, and can be precipitated by various metabolic stressors. Late-onset ornithine transcarbamylase deficiency is not merely related to a type of genetic variation, but also to the complex relationship between genetic and environmental factors that result in hyperammonemia; therefore, it is difficult to predict the prevalence of neurological symptoms in late-onset ornithine transcarbamylase deficiency. Most common acute neurological manifestations include psychological changes, seizures, cerebral edema, and death; subacute neurological manifestations include developmental delays, learning disabilities, intellectual disabilities, attention-deficit/hyperactivity disorder, executive function deficits, and emotional and behavioral problems. This review aims to increase awareness of late-onset ornithine transcarbamylase deficiency, allowing for an efficient use of biochemical and genetic tests available for diagnosis, ultimately leading to earlier treatment of patients.

• The Journal of Korean Medicine
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• v.34 no.3
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• pp.13-24
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• 2013

Objectives: The aims of this study were to investigate the availability of diagnosis of Yin-deficiency in the elderly with xerostomia and factors influencing subjective oral dryness. Methods: We surveyed 50 patients recruited by the clinical trial, 'Efficacy of Yukmijihwang-tang on Xerostomia in the Elderly: A Randomized, Double-blind, Placebo-controlled, Two-center Trial'. The subjects were assessed on their subjective oral dryness using the Dry Mouth Symptom Questionnaire (DMSQ). Their salivary functions were measured by Unstimulated Salivary Flow Rate (USFR) measurements. In addition, the subjects were evaluated on their Qi-stagnation and Yin-deficiency conditions using the Qi-stagnation questionnaire and Yin-deficiency questionnaire. Results: There were statistically significant correlations between three variables (USFR, DMSQ score and Qi-stagnation score) and Yin-deficiency score. In the multiple regression analysis, the regression model was statistically significant (F = 10.273, p < .001). The factor most strongly influencing the subjective oral dryness was USFR (${\beta}$ = -0.386). Yin-deficiency had the next strongest impact on the subjective oral dryness (${\beta}$ = 0.371). Qi-stagnation affected the subjective oral dryness weakly (${\beta}$ = 0.075). In the simple regression analysis, Yin-deficiency had a statistically significant effect on each of six subscales of DMSQ (p < .01). Among the six subscales, DMSQ-1 ('Oral dryness at night or on awakening') was the most strongly influenced by Yin-deficiency. Conclusions: The results of this study show that the diagnosis of Yin-deficiency in the elderly with xerostomia was available and Yin-deficiency was an important factor influencing the subjective oral dryness. Therefore, the consideration of Yin-deficiency is significant for diagnosis and treatment in the elderly with xerostomia.

• Journal of Korean Medicine Rehabilitation
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• v.24 no.2
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• pp.95-106
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• 2014

Objectives The purpose of this study is to analyse research trends about obesity pattern identification in traditional chinese medicine. Methods Electronic searches were performed with China National Knowledge Infrastructure (CNKI). The first key words were "肥畔", "肥滿" and second key words were "病因", "分型", "病機", "辨證", "分流". We classified the papers by year and content. We investigated frequency of chinese obesity pattern identification. Results 48 studies were finally included. Papers were published between 1987 and 2013. More than half of the total were published since 2009. 36 studies were literature and Paper review studies. 16 studies were clinical research. There were 'qi deficiency', 'spleen deficiency', 'yang deficiency', 'yin deficiency', 'stomach heat ', 'qi stagnation', 'liver qi depression', 'phlegm-dampness', 'phlegm-heat', 'blood stasis' in chinese obesity pattern identification studies. 'Phlegm-dampness' was used most frequently, followed by 'spleen deficiency', 'yang deficiency', 'blood stasis', 'qi stagnation', 'liver qi depression', 'stomach heat ', 'qi deficiency', 'yin deficiency ' and 'phlegm-heat' in literature and paper review studies. 'Phlegm-dampness' was used most frequently, followed by 'yang deficiency', 'spleen deficiency', 'liver qi depression', 'stomach heat ', 'blood stasis ', 'yin deficiency', 'qi deficiency', 'phlegm-heat ' and 'qi stagnation' in clinical research. Conclusions Based on studies of chinese obesity pattern identification, More clinical trials and obesity pattern identification studies are needed.

• Journal of Nutrition and Health
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• v.52 no.6
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• pp.552-558
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• 2019

Purpose: Although vitamin D deficiency is common among Korean adolescent girls and young women, few studies have explored the potential health effects of vitamin D deficiency in this vulnerable population. This study examined the association between vitamin D deficiency and anemia in Korean adolescent girls and young women. Methods: The data from the Korea National Health and Nutrition Examination Survey 2008 ~ 2014 were used. A total of 3,643 girls and adult women aged 12 to 29 who provided all the information (including serum 25-hydroxy vitamin D, hemoglobin, and/or serum ferritin) needed for the analysis were included in the analysis. Demographic, lifestyle, and health data were obtained through survey questionnaires. Anemia and iron deficiency anemia were defined according to the World Health Organization cut-offs. Multivariable logistic regression, and restricted cubic spline regression were used in the analysis. Results: In fully adjusted logistic regression models, the vitamin D deficiency was significantly associated with higher prevalences of anemia (odds ratio (OR): 1.61, 95% confidence interval (CI): 1.04 ~ 2.49) and iron deficiency anemia (OR: 1.43, 95% CI: 1.01 ~ 2.03). In a cubic spline regression model, we observed a dose-response relationship between serum 25(OH)D concentration and anemia, and this linear relationship was also clearly observed between serum 25(OH)D concentration and iron deficiency anemia. Conclusion: Vitamin D deficiency may be associated with a higher prevalence of iron deficiency anemia and anemia in adolescent girls and young women. Alternatively, vitamin D deficiency may be a concurrent event for patients with anemia, which we cannot distinguish in this cross-sectional study. Further studies are needed to verify the causality in this population of low vitamin D levels.

• Proceedings of the KSR Conference
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• 2001.10a
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• pp.481-487
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• 2001

In this study, the relation between cant deficiency(C＇) and rail wear in Seoul Metro Line 5 with STEDEF track structure(concrete bed) is studied. As a result, it is found that cant deficiency have a direct influence on rail wear, and under the condition that other negative effects are neglected, the cant deficiency in Metro Lines is demanded to set as little as possible.

• Journal of applied mathematics & informatics
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• v.29 no.3_4
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• pp.949-953
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• 2011

It is interesting to know the behavior of a network from its structure. One interesting topic is to find a relation between the existence of a positive equilibrium of the reaction network and its structure. One approach to study this topic is using the concept of deficiency. Another is using some conditions on nodes, which can apply to large-size networks compared to deficiency. In this work, we show the relation between deficiency and the conditions.

• Journal of Korean Institute of Industrial Engineers
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• v.24 no.3
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• pp.407-416
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• 1998

For fast Cholesky factorization, it is most important to reduce the number of nonzero elements by ordering methods. Generally, the minimum deficiency ordering produces less nonzero elements, but it is very slow. We propose an efficient implementation method. The minimum deficiency ordering requires much computations related to adjacent nodes. But, we reduce those computations by using indistinguishable nodes, the clique storage structures, and the explicit storage structures to compute deficiencies.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.214.4-215
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• 2003

In galactose metabolic pathway : there are three inborn metabolic disorders galactokinase deficiency (galactosemia type II), galactose-1-phosphate uridyl transferase(GALT) daficiency (galactosemia type I ), uridine diphosphate galactose-4-epimerase deficiency (galactosemia typeIII). Among these disorders GALT deficiency is the most severe and common. Infants with GALT deficiency fail to metabolize galactose-1-phosphate. As a consequence, galactose-1-phosphate and galactose are accumulated in blood in which GALS enzyme plays the role of a pathognomonic marker. (omitted)