• Title/Summary/Keyword: decuroside I

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Coumarins from the Roots of Angelica decursiva-albiflora (개바디 뿌리의 쿠마린성분)

  • Jung, Nam-Il;Yook, Chang-Soo;Lee, Hyeong-Kyu
    • Korean Journal of Pharmacognosy
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    • v.25 no.4 s.99
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    • pp.311-318
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    • 1994
  • From the root of Angelica decursiva-albiflora Yook, which has been used as a folk medicine for a sedative, analgesic and expectorant, four free coumarins, e.g., decursidin(I), decursin(II), umbelliferone(III) and nodakenetin(IV), and two coumarin glycosides, e.g., nodakenin(V) and decuroside I(VI) were isolate. The cytotoxicity of nodakenin(V) against L-1210 leukemia cells was less effective than cisplatin, but in the nephrotoxicity against rabbit kidney proximal tubular cell nodakenin(V) showed remarkably less nephrotoxicant than cisplatin.

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