• 한방재활의학과학회지
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• 제21권3호
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• pp.33-43
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• 2011

Objectives : The purpose of this study was to investigate the influence of modified fasting therapy using fermented herbal medicine on the changes of body compositions. Methods : This study was carried out on 11 patients who carried out modified fasting therapy using fermented herbal medicine. They went through reducing food intakes period(7 days), fasting period(10~14 days) and refeeding period(10~14 days). Body compositions(weight, BMI(body mass index), skeletal muscle mass, body fat mass, percent body fat, basal metabolic rate, waist-hip ratio, visceral fat area) were measured at each state. And then the data was analyzed. Results : 1. The weight and BMI decreased during the reducing food intakes period and the fasting period, and increased during the refeeding period. But the weight and BMI decreased during the fasting therapy period, as a whole. 2. The skeletal muscle mass decreased during the fasting period and increased during the refeeding period. As the final outcome, for the whole fasting therapy period, decrease of skeletal muscle mass didn't show significance. The body fat mass and percent body fat decreased during the reducing food intakes period, the fasting period and the refeeding period. 3. The basal metabolic rate decreased during the fasting period and increased during the refeeding period. As the final outcome, for the whole fasting therapy period, decrease of basal metabolic rate didn't show significance. 4. The waist-hip ratio decreased during the fasting period and the refeeding period. The visceral fat area decreased during the fasting period and refeeding period. Conclusions : Results from this investigation showed that modified fasting therapy using fermented herbal medicine have positive effects on changes of body compositions. This results are expected to compensate the defects of existing fasting therapy.

• Gut and Liver
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• 제12권6호
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• pp.633-640
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• 2018

Background/Aims: Obesity is a risk factor for gastroesophageal reflux disease (GERD), with several studies demonstrating positive associations between body mass index (BMI) and GERD symptoms. However, little is known about the effect of BMI changes on erosive esophagitis (EE). In this study, we investigated whether BMI reduction could resolve EE. Methods: A retrospective cohort study was performed to assess the natural course of EE according to changes in BMI. Participants undergoing health check-ups from 2006 to 2012 were enrolled, and 1,126 subjects with EE were included. The degree of esophagitis was measured by upper endoscopy and serially checked over a 5-year follow-up. Logistic regression and Cox proportional hazards models were used to investigate the association between BMI reduction and EE resolution. Results: Substantial weight loss is associated with EE resolution. The adjusted odds ratio for EE resolution was 1.44 (95% confidence interval [CI], 1.09 to 1.92) among participants with a decrease in BMI compared to those with no decrease in BMI. The EE resolution rate was related to the degree of BMI reduction. The effect of weight loss on EE resolution was higher among subjects who lost more weight. Compared with subjects with no decrease in BMI, the hazard ratios for EE resolution were 1.09 (95% CI, 0.89 to 1.35), 1.31 (95% CI, 1.01 to 1.72) and 2.12 (95% CI, 1.44 to 3.12) in subjects with BMI reductions of ${\leq}1$, 1-2, and >$2kg/m^2$, respectively. Conclusions: EE resolution is associated with a decrease in BMI, and weight loss is potentially an effective GERD treatment.

• 대한한방소아과학회지
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• 제19권2호
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• pp.1-11
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• 2005

Objectives : The purpose of this study is to investigate the effect of fasting therapy on the changes of body composition in obese adolescents. Methods : We examined the body composition of obese adolescents three times; before fasting, on the second refeeding day, two or four weeks later. Results : Body weight, body mass index(BMI), basal metabolic rate(BMR) and lean body mass (LBM) were decreased during the fasting, whereas percent-fat was increased. After fasting, patients have the dietary period. During this period BMR and LBM were increased and the decrease of percent-fat was continued. Conclusions : It seems that fasting therapy with keeping up well-controlled dietary period and receiving oriental medical management can be useful to decrease percent-fat in obese patients.

• Advances in Traditional Medicine
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• 제10권2호
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• pp.66-78
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• 2010

Acute (24 h) and chronic (90 days) oral toxicity studies on the ethanol extract of Trigonella foenumgraecum Leguminosae (L.) seeds were carried out. Acute dosages were 0.5, 1.0 and 3 g/kg while chronic dosage was 100 mg/kg per day of the extract. All morphological, biochemical, haematological and spermatogenic changes, in addition to mortality, body weight changes and any change in vital organs were recorded. Histopathological investigations were done on vital organs. Growth arrest in the treated animals was observed. The treated mice gained no significant weight during chronic treatment while there was a significant gain in body weight of the control group mice. Biochemical studies revealed a significant decrease in blood sugar levels of fenugreek treatment groups while haematological parameters remained comparable to the control. In the treatment, male group there was a significant decrease in weight of testes as compared to the control. There was a marginal weight gain in kidney weight of mice after chronic treatment as compared to the control. Fenugreek chronic treatment caused a highly significant spermatotoxic effects in male mice.

• 대한한방부인과학회지
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• 제34권3호
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• pp.65-78
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• 2021

Objectives: This study was aimed to investigate the weight change of the high-risk group and the general maternal group and weight-relating factors in the early postpartum period. Methods: We retrospectively reviewed the medical records of those who received postpartum care from January 1, 2020, to December 31, 2020, in the postpartum care center affiliated with one Korean Medicine hospital. A total of 257 postpartum women's medical charts were included and divided into the high-risk group and the general maternal group. We investigated the weight changes and Body mass index (BMI) of the postpartum women and compared the difference between the two groups after taking the postpartum care. Finally, we used a Pearson correlation analysis to identify the weight-relating factors in the early postpartum period. Results: All the postpartum women showed the following results; 33.81±4.03 years old as the mean age; 22.23±3.28 as pre-pregnancy BMI; 58.21±9.18 kg of pre-pregnancy weight increased into 70.75±9.70 kg in the last month of pregnancy. Of the total 257 patients, 149 (58.0%) of high-risk pregnancy experience and 108 (42.0%) of general pregnancy were included. The edema index right after childbirth was significantly higher in the high-risk group than in the general maternal group (p<0.001), but there was no significant difference in BMI. After treatment with Korean medicine treatments, body weight, BMI, and edema index decreased significantly in both groups (p<0.01). As a result of correlation analysis, weight gain during pregnancy had a significant negative correlation with pre-pregnancy weight and pre-pregnancy BMI and a significant positive correlation with weight and BMI of the last month of pregnancy. In particular, pre-pregnancy BMI and body weight showed a significant negative correlation only in the high-risk group. Postpartum weight loss was significantly positively correlated with pre-pregnancy weight, pre-pregnancy BMI, weight & BMI of the pregnancy last month, weight gain during pregnancy, and decrease in edema (p<0.01) Conclusions: The weight during pregnancy of the high-risk group increased in inverse proportion to the pre-pregnancy BMI. The level of edema right after childbirth was significantly higher than that of the general maternal group, but showed a significant decrease after 2 weeks of Korean medicine treatments. Although it implicates the need for active Korean medicine treatments in the early postpartum period, further studies with controlled groups are needed.

• Journal of Nutrition and Health
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• 제36권6호
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• pp.589-602
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• 2003

This study was designed to investigate the effects of weight reduction and changes in serum lipid composition using a commercial uncooked powdered food (UPF) diet on 27 obese hyperlipidemic women over a period of 12 weeks. We replaced the standard breakfast and dinner of each of the subjects with UPF. Their dietary intake status was evaluated by 24-hour recall method. Their body compositions were measured using a body fat analyzer. Also, we conducted hematological, clinical and lipid profile analyses of their blood. Their intake of energy, lipid and protein significantly decreased as the subjects started to take UPF, but their intake of vitamins and minerals, other than iron, increased. Due to the energy intake decrease, the subjects' weight, body fat and waist circumference significantly decreased. Among the lost weight the percentage of the body fat was high. We judged that this process of losing weight was successful in obese hyperlipidemic women. Serum HDL-cholesterol gradually increased and serum total-cholesterol, LDL-cholesterol, triglyceride levels showed gradual decreases. When obese hyperlipidemic women replaced two of three meals with UPF for 3 months, we were able to see useful changes like decreased body fat and serum lipid. Complete judgment on the usefulness of UPF may be difficult but if people take a standard meal once a day and replenish their iron by taking UPF twice a day, we assume that replacing UPF with balanced regular meal not be a problem in nutritional status. Our results show that UPF is effective in the diet therapy of obese hyperlipidemic women.

• 동아시아식생활학회지
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• 제13권1호
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• pp.39-55
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• 2003

This study was conducted to investigate the effect of an uncooked powdered food(UPF) on the weight loss and changes of the biochemical nutritional status for 20 overweight and 26 obese women in Iksan area. We just replaced common breakfast and dinner of the subjects with UPF. Their dietary intake status was evaluated by 24-hour recall method. Also anthropometric and biochemical measurements before and after the UPF program were estimated. The intake of energy, lipid and protein decreased and the quality of meals improved as people started to take UPF. Due to the energy loss by taking UPF, weight and body fat decreased significantly. The percentage of the body fat was high among the weight lost, from which we judged that the process of losing weight was successful. It is hard to predict whether weight loss will occur to people who are already in shape or not, but if overweight and obesity people regularly take UPF instead of other food products, we assume that UPF will help lessening the body fat. The most positive change among biochemical changes by taking UPF was the decrease of serum lipid contents. When overweight and obesity women replaced two out of three meals with UPF for 3 month period, no significant nutritional problems occurred. It seems that the 12weeks of UPF program used in this study was effective in improving anthropometric indices without producing the deficiency of iron or other susceptible nutrients.

• International Journal of Industrial Entomology and Biomaterials
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• 제14권2호
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• pp.121-126
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• 2007

Obesity is a major risk factor for cardiovascular disease. In our case study using animal models for disease states such as obesity or hypertension, we found that, Isaria sinclairii remarkably reduced body weight and ameliorated metabolic abnormalities in Zucker and SHR rats. Genetically obese (fa/fa) Zucker rats were one animal model chosen for this study. Four groups of rats received a standard diet and were treated orally with the following test samples daily for 8 weeks: saline (negative control), ethanol extracts of I. sinclairii, hot water extract of I. sinclairii, or $Xenical^{(R)}$ (30 mg/kg, positive control). Mild reductions (6.3%) in body weight gain were observed in the groups treated with the hot water extract of I. sinclairii compared to the control after 8 weeks. Interestingly, organ weight was greatly reduced by this Dongchunghacho (I. sinclairii), in parallel with the mild reductions in body weight gain and reductions in abdominal fat (adipose tissue). Also observed was a 4.1 % decrease in the ratio of heart weight/body weight compared to the control group. As a hypertensive animal model, SHR (spontaneously hypertensive rat) and WKY (Wistar Kyoto) rats were also administered these extracts for one month. Treatment with the hot water extract of I. sinclairii caused greater reductions in body weight gain for the SHR group (10.9%) compared to the WKY group's (5.2%). Based on these results, I. sinclairii extracts contain selective action for anti-obesity activity, naturally occurring candidate for regulation of body weight increase, as demonstrated in the present study.

• 한국보건간호학회지
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• 제15권2호
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• pp.363-375
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• 2001

The purpose of this study is to analyse the effects of obesity management program in food attitude and food habit, body composition(body fat ratio, body fat weight, lean body mass, total body water), abdominal girth(waist, hip, thigh), and serum lipid level(cholesterol, low density lipoprotein, triglyceride, phospholipid, NE fatty acid, high density lipoprotein) of middle aged women. Data for the study were collected from July 4 to August 25, 2000. The study objects were 20 middle aged women(10 controls and 10 experimental objects) from 40 to 50 years old who had body fat ratio more than $30\%$ and waist girth more than 80cm. The results were as follows: 1. Similarity test between experimental group and control group processed by serum HDL level showed the significant difference(t=3.25, p=0.004), but that processed by age, body weight, body fat ratio, body fat weight, lean body mass, total body water, waist girth, hip girth, thigh girth, cholesterol level, LDL level, triglyceride level, NE fatty acid level, food attitude and food habit score showed no significant difference(p>0.05). These findings imply that the two groups are similar in the sample distribution. 2. The effects of the abdominal obesity management program The obtained results indicate that the abdominal obesity management program in middle aged women changes the food attitude & the food habit. decreases the body fat ratio & the body fat weight and increases the lean body mass, and decreases the girth of waist & hip and the serum level of cholesterol & LDL. Therefore, it is concluded that the abdominal obesity management program can be applied for nursing intervention to decrease the body fat weight and abdominal obesity.

• Journal of Nutrition and Health
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• 제45권4호
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• pp.315-323
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• 2012

Korean undergraduate students attempt to lose weight but often fail due to utilizing ineffective weight loss strategies. Some diet programs have succeeded, yet, they have not provided adequate skills for long-term weight maintenance. The aim of the study was to determine the effect of a low calorie diet and exercise with nutritional education on weight loss, serum lipid profiles, nutrient intakes, and dietary behavior modification in overweight and obese undergraduate students. The subjects in the low calorie diet group (LCD; n = 12) and the low calorie diet plus exercise group (LCDE; n = 13) had the same goal of losing 4 kg during a 12 week program. Nutrient intakes were assessed by the 24 hour recall method. Also, food habits and dietary behaviors were investigated by self-administered questionnaires before and after the weight control program and one month after completing the program. LCD and LCDE groups lowered body weight by 2 kg and 1 kg, respectively, although they decreased calorie intake by 355 and 287 kcal per day compared to intakes prior to the study. Body fat mass decreased in both the LCD and LCDE groups; however, the decrease was greater in the LCDE group. In addition, only the LCDE group increased muscle mass. The LCD group had a slightly better effect in reducing body weight, body fat, and waist circumference than the LCDE group. However, their decrease was reversed after the mid-study check in the LCD group; the reduction was better maintained and decreased more in the LCDE group. However, serum lipid profiles were already in borderline prior to the study; moreover, they were not modified after losing weight. The dietary behavior program helped students to develop better dietary habits. In conclusion, the combination of a low calorie diet and exercise is necessary in order to maintain longer weight loss by increasing muscle mass and decreasing body fat.