The objective of this study was to evaluate the effect of exogenous ghrelin on the behaviors, weight gain, and feed intakes of weanling piglets. A total of 25 pairs of Duroc$\times$Landrace$\times$Large White piglets weaned at 21 days of age were used in this experiment which finished on day 36. Each pair of healthy piglets from the same litter with similar body weight and of the same gender were selected and randomly arranged to ghrelin or control groups. Thus, there were 50 piglets (ghrelin 25; control 25) kept in 10 pens (ghrelin 5; control 5) and 5 piglets per pen. Initial body weight of the pigs did not differ between the control and ghrelin treatment ($7.43{\pm}0.17kg$; p = 0.81). Experimental pigs were infused with ghrelin ($1{\mu}g/d$ pig) via the marginal ear vein between 0750 and 0800 h at 22, 23, 24 days of age. Control pigs were infused with 0.9% saline. Feed consumption was measured on days 23, 24, 25, 29 and 36. Body weight was measured on days 22, 23, 24, 25, 29 and 36. Behavior data of individual piglets were collected by real-time observation from 0800-1500 h through remote supervisory equipment at 22, 23 and 24 days of age. The results indicated that ghrelin infusion could increase drinking (p<0.05) and lying behaviors (p<0.01) and decrease mounting behaviors (p<0.05). No significant influence of ghrelin was found on average daily weight gain (ADG) and average daily feed intake (ADFI) in this experiment (p>0.05). In conclusion, exogenous ghrelin by the method above and at the dosage of $1{\mu}g/d$ pig could cause a variety of behavioral effects, but not improve performance of weanling piglets.
Three hundred gram of Korean ginseng root was extracted with 95% ethanol on a boiling water bath for about 300 hr. Evaporation of alcohol yieled 50.2g of dark brown residue which was used by dissolving 4 mg of the residue in 1 ml of physiological saline. The ginseng group and the saline group received each day 0.5 ml per 100 g body weight of ginseng extract and physiological saline, respectively. Both the ginseng and saline group with stress were exposed to positive radial acceleration (1∼29g), cold (5$^{\circ}C$, 0$^{\circ}C$ &-10$^{\circ}C$) and heat (35$^{\circ}C$) environment, and surgical stress. After termination of the last stress, the tolerance, body weight, visceral organ weight, basal metabolism rate, rectal temperature, the number of erythrocyte and leucocyte, hemoglobin level, hematocrit ratio, total serum protein content and it's fraction and the content of adrenal ascorbic acid in the experimental animal exposed to stress were measured and at the corresponding periods, the same measurements were also carried out with the ginseng and the saline groups without stress exposure (serving as control). Results obtained were as follows. 1. Administration of ginseng does depressed the decrease of the tolerance, body weight, visceral organ weight, basal metabolism rate, the number of erythrocyte, hemoglobin value, hematocrit ratio and the A/G ratio in the mice and rats exposed to various stress. 2. The change of the rectal temperature, eosinophile counts, total serum protein content and the content of adrenal ascorbic acid of ginseng group that exposured to various stress facilitates the reaction to, and accelerates the recovery from the stress. 3. Even after hypophysectomy which served the link between the central and the peripheral portion of the stress mechanism, the adrenal ascorbic acid content of ginseng group decreased significantly more than that of the saline group 30 min. after administration of ACTH, while the value approached the normal level significantly closer in the ginseng group than in the saline group 1 and 2 hr after ACTH administration. Judging from the above results, it is concluded that administration of ginseng extract tolerated the experimental animals under the environment of stressfu1 stmuli, although the ginseng has no significant influence upon the stress mechanism in the absence of stressful stimuli. The site of action of the ginseng appears to be in the peripheral portion of the stress mechanism.
Kim, Yong-Soon;Song, Moon-Yong;Kim, Jin-Sik;Rha, Dae-Sik;Jeon, Yong-Joon;Kim, Ji-Eun;Ryu, Hyeon-Yeol;Yu, Il-Je;Song, Kyung-Seuk
Toxicological Research
/
v.25
no.3
/
pp.140-146
/
2009
This study was performed to evaluate the toxicity of cadmium selenide for a period of 28 days in Sprague-Dawley rats. Each of 10 healthy male and females rats per group received daily oral administration for 28-day period at dosage levels 30, 300 and 1,000 mg/kg of body weight. Mortality and clinical signs were checked, and body weight, water intake and food consumption were also recorded weekly. There were no dose-related changes in food consumption or urine volume. All animals survived to the end of study with no clinical signs or differences in body weight gain observed when compared with the control group. At the end of study, all animals including control group, were subjected to necropsy. Blood samples were collected for hematology tests including coagulation time and biochemistry analysis. Blood coagulation time and relative organ weight were unaffected by all received doses. White Blood Cell (WBC) counts significantly increased in the 300 mg/kg administered male animal group when compared to the control. Monocyte (MO) value were also increased significantly in both 300 and 1,000 mg/kg male animal group. However, Mean Corpuscular Volume (MCV) were significantly decreased compared with the control in the 1,000 mg/kg dose groups for male and female animals. Mean Corpuscular Hemoglobin (MCH) decreased significantly for female in the 300 and 1,000 mg/kg group compared to the control. Blood biochemical values of Inorganic phosphorus (IP) were significantly increased in both the 300 and 1,000 mg/kg dose groups in male animals when compared to the control. Creatinine (CRE) levels indicated significant increase in kidney function for the female, 30 mg/kg dose group when compared with control. There was a significant decrease in thymus absolute organ weight in the female, 1,000 mg/kg dose group when compared with control. Histopathological findings revealed no evidence of injury related to cadmium selenide except for one case of focal hepatic inflammation in the high dose (1,000 mg/kg) group. One case of lung inflammation was also seen in the control group. Basis on these result, the No Observable Adverse Effect Level (NOAEL) of cadmium selenide was determined to be more than 1,000 mg/kg/day for male and female rats under conditions in this study.
The purpose of this study was to investigate effects of changes in body composition due to combined exercise on balance of the 20' obese women. Based on voluntary participation, 21 obese women in twenties were randomly divided into : Control(no exercise, n=7), Group I (aerobic exercise 50 minutes, n=7), Group 2 (combined exercise 50 minutes, n=7). All groups conducted allocated program five times a week for six weeks. At post and pre-experiment and at the time of each measurement, changes of body composition and balance among the three groups were statistically analyed using SPSS 18.0 ver. Compared to pre-experiment, Group I, II showed decrease of weight and body fat rate, but Group II showed both increase of muscle mass and decrease of body mass index(p<0.05). In balance ability, Group II showed improvement of static and dynamic balance, meanwhile Group I showed only improvement of static balance. Therefore, this research showed that combined exercise had positive effects on balance by increasing muscle mass and changing body composition.
This study was conducted to evaluate the effects of duck-meat consumption on adult disease risk factors, including body compositions, hematological variables, and serum metabolic and lipid profiles in adult human males. To obtain results, 20 adult males aged 20 to 25 were subjected to a diet of 600 g/day of duck-meat for 4 wk, after which body composition, hematological variables, and serum metabolic and lipid profiles were investigated to determine if there was a relationship between duck-meat consumption and adult disease risk factors. The results revealed that high amounts of duck-meat intake did not negatively alter body indices such as body weight, fat mass, body mass index (BMI), % body fat or waste-to-hip ratio (WHR). Furthermore, there were statistically insignificant changes in the number of blood cells, although this number did increase significantly following intake of duck-meat. Moreover, general decreases in serum metabolic parameters were observed, but none of these changes were significant with the exception of the concentration of blood urea nitrogen (BUN). The serum concentrations of LDL-cholesterol also showed a statistically significant decrease by 5.86%. Therefore, this study suggests that the ingestion of duck-meat not only significantly increased the RBC count but also decreased BUN and LDL-cholesterol concentrations in adult males.
Attempts were made to investigate the conditions of mycelia of one low-temperature type strain and one high-temperature type strain of shiitake showing poor fruit-body formation in bed-log, and to survey harmful microorganisms formed on the log surface in Gapyung County, Korea. When tested the growing ability of mycelia, the low-temperature type strain showed ca. 1.1% decrease compared with preserved original strain. And, the high-temperature type one showed ca. 8.0% decrease. The growth of isolated mycelia was tested in sawdust medium. The high-temperature type strain showed ca. 10.8% decrease compared with original strain, and the low-temperature type one showed ca. 25.1% decrease. Weight reduction rate was investigated. The high-temperature strain showed ca. 20.1% decrease and the low-temperature one ca. 19.0%. When compared with non-treatment, original high-temperature type strain showed 107.0% decrease, the isolated high-temperature type strain 49.5%, original low-temperature type one 85.4%, isolated low-temperature type one 50.0%. As the results of confrontation culture, the high-temperature type strain and the low-temperature type one were same as the original ones, respectively. And, in the bed-logs, Hypoxylon truncatum, Coriolus versicolor, Inonotus xeranticus, Daedaleopsis tricolor, Graphostroma platystoma, two species of Myxomycetes, Trichoderma sp. Hypoxylon fragiforme, H. howeianum, and Nitschkia confertula were observed as harmful microorganisms, and the bed-logs were not in good condition.
This study was conducted to investigate the influence of dietary rapeseed meal (RSM) on growth performance, blood profiles, nutrient digestibility and economic benefit of growing-finishing pigs. A total of 120 growing pigs ($[Yorkshire{\times}Landrace]{\times}Duroc$) with an initial body weight (BW) $29.94{\pm}0.06kg$ were used in this experiment. Pigs were randomly allotted into 1 of 5 treatments in a randomized complete block design and 6 replicates with 4 pigs per pen. Treatments were divided by dietary RSM supplementation levels (0%, 3%, 6%, 9%, or 12%) in growing-finishing diets. A linear decrease (p<0.05) of BW and average daily gain (ADG) were observed at 13th wk of finishing and overall periods of pigs. Additionally, gain-to-feed ratio (G/F) tended to decrease by dietary RSM supplementation in growing-finishing diets (linear, p = 0.07 and quadratic, p = 0.08). Concentrations of serum triiodothyronine and thyroxine were not influenced by dietary RSM treatments whereas thyroid gland and liver weight were increased at 13th wk of finishing period (linear, p<0.05; p<0.01) by increasing dietary RSM supplementation level. In blood profiles, serum total cholesterol and low density lipoprotein cholesterol concentrations were not differed by dietary treatments at 13th wk of finishing period whereas concentration of serum high density lipoprotein cholesterol was affected by the supplementation level of RSM, resulting in a linear RSM level responses (p<0.05). Serum blood urea nitrogen concentration tended to decrease (linear, p = 0.07; p = 0.08) at 6th wk of growing and 13th wk of finishing periods and digestibility of dry matter tended to decrease by dietary RSM (linear, p = 0.09). Crude protein, crude fat and nitrogen retention, whereas, were not affected by dietary RSM supplementation level. In the economic analysis, feed cost per weight gain was numerically decreased when RSM was provided up to 9%. Consequently, RSM could be supplemented to growing-finishing diets up to 9% ($3.07{\mu}mol/g\;Gls$) without detrimental effects on growth performance of growing-finishing pigs.
Kyungun Bae;Sung Hyun You;Dabi Shin;Yuncheol Ha;Hongmin Kim;Byungchan Pak;Hyosang Kim;Shinae Park
Journal of Korean Society of Occupational and Environmental Hygiene
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v.34
no.1
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pp.77-84
/
2024
Objectives: Interventions promoting physical exercise and healthy habits in workplaces have been shown to be effective in reducing risk factors for metabolic syndrome. This study was conducted to examine the effects of an individualized conditioning exercise program of IT company office workers with or at higher risk of metabolic syndrome. Methods: A total of 444 IT company office workers with or at higher risk of metabolic syndrome participated in a 3-month conditioning exercise program. Body composition data using bioelectrical impedance analysis and cardiopulmonary data using cardiopulmonary exercise testing from 53 individuals (mean age: 34.8 ± 7.1 years, sex : 21% female, height : 170.4 ± 6.8 cm, weight : 75.2±12.2 kg, body mass index : 25.8±3.3 kg/m2) who have successfully completed pre-test, intervention, and post-test were analyzed. The 12 weeks intervention encompassed: (1) health counseling (2) supervised exercise(endurance-based, aerobic exercise, or circuit training once a week for 50 minutes at heart rate reserve(HRR) of 77-95%) (3) self-directed exercise and biweekly health screening checks. Results: The results indicated a significant decrease in body weight, body fat mass and body mass index, respectively. Moreover, VO2peak, AT VO2 and AT Time significantly improved, respectively. Resting blood pressure(SBP/DBP) showed positive changes but were not statistically significant. We observed the correlation between characteristics of participants and rate of changes in cardiopulmonary outcomes of participants, there are no significant correlation. These results indicate positive changes in body composition and cardiorespiratory fitness parameters following individualized conditioning exercise program. Conclusions: Individualized workplace exercise program for preventing metabolic syndrome can lead to improvements in body composition and cardiorespiratory fitness.
Journal of the Korea Society of Computer and Information
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v.29
no.3
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pp.137-146
/
2024
The purpose of this study was to determine the effects of 12 weeks of WB-EMS training on body composition and heart rate variability based on BMI Level in Women. The subjects of the study were premenopausal women, and they were classified into the BMI-N(n=15) group for BMI<25, the BMI-1(n=16) group for BMI=25~29.9, and the BMI-2(n=9) group for BMI>30. And then, WB-EMS training was performed of 3 times a week for 12 weeks. Body composition and HRV were measured before and after the participation in exercise, which were subjected to a repeated-measures two-way ANOVA. In the case of a significant interaction between time and group, paired sample t-tests were conducted for a post-hoc analysis within each subject group. Tukey's method was used for post-hoc testing of differences between groups, and the significance level was set at 0.5. The results were as follows; First, The effect of WB-EMS training was found in all variables of body composition. In particular, Weight, BMI, FFM, and FM decreased the most in the BMI-2 group, followed by the BMI-1 and BMI-N groups. %BF and VF decreased the most in the BMI-2 group. Second, There was a difference in BPM in all groups, and the BMI-2 group showed the greatest decrease. There were differences in SDNN and RMSSD for each group, and there was no difference according to obesity level. There was no difference in LF, HF, and LF/HF ratio. In conclusion, it was confirmed that WB-EMS training can be an exercise therapy that has a positive effect on the body composition change and cardiac circulatory system in women with a high level of obesity.
The aim of this study was to determine the effects of tote bag weight on muscle thickness of pectroalis minor and tone of upper trapezius in young adult women. 27 women habitual of carrying tote bags. The subjects were measured the tone of the upper trapezius muscle and the thickness of the pectoralis minor muscle while carrying tote bags with the weight of 0%, 5%, 7.5% and 10% of the subjects' body weight. As the weight load increased, the upper trapezius muscle demonstrated significantly increased muscle tone (p<.05). additionally, a significantly increased thickness in the pectoralis minor muscle was noted(p<.05). These findings suggest that the habit of carrying a tote bag on the wrist may be disadvantageous to improving the two muscles in young women. Therefore, this study recommend women who likely used tote bag decrease the weight of the bag.
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