• 수산해양교육연구
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• 제26권3호
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• pp.525-534
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• 2014

This study has examined the effect of after-school physical activity on body composition and health related fitness of middle school students. The duration of after-school physical activity training program of this study is 12 weeks, the training time in 1 hours warming-up 10 minutes, the skill training 45 minutes and cool down did in 5 minutes. Exercise frequency is 5 time per week. Height basketball class, soccer class, subject class showed statistically meaningful increase between group variance showed statistically meaningful. Weight basketball class, soccer class, showed statistically meaningful decrease. Muscle mass basketball class showed statistically meaningful increase, soccer class showed statistically meaningful decrease. Cardiopulmonary basketball class, soccer class, showed statistically meaningful decrease. Explosive muscular strength basketball class, soccer class, showed statistically meaningful decrease. subject class showed statistically meaningful increase, between group variance showed statistically meaningful. Flexibility basketball class showed statistically meaningful increase, soccer class. Muscular strength basketball class, soccer class, subject class showed not statistically meaningful different.

• Archives of Pharmacal Research
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• 제27권2호
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• pp.232-238
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• 2004

Trolox is a hydrophilic analogue of vitamin E. The aim of this study was to investigate its effects on hepatic injury, especially alteration in cytochrome P450 (CYP)-dependent drug metabolism during polymicrobial sepsis. Rats were subjected to polymicrobial sepsis by cecal ligation and puncture (CLP). The rats were treated intravenously with Trolox (2.5 mg/kg) or vehicle, immediately after CLP. Serum aminotransferases and lipid peroxidation levels were markedly increased 24 h after CLP. This increase was attenuated by Trolox. Total CYP content and NADPH-P450 reductase activity decreased significantly 24 h after CLP. This decrease in CYP content was attenuated by Trolox. At 24 h after CLP, there was a significant decrease in the activity of these CYP isozymes: CYP1A1, 1A2, 2B1, and 2E1. However, Trolox differentially inhibited the decrease in CYP isozyme activity. Trolox had little effect on the decrease in CYP1A1 activity but Trolox significantly attenuated decreases in CYP1A2 and 2E1 activities. In fact, Trolox restored CYP2B1 activity to the level of activity found in control rats. Our findings suggest that Trolox reduces hepatocellular damage as indicated by abnormalities in hepatic drug-metabolizing function during sepsis. Our data also indicates that this protection is, in part, caused by decreased lipid peroxidation.

• 한국지반공학회논문집
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• 제28권9호
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• pp.69-83
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• 2012

국내에서 출토빈도가 높은 9개 암종을 대상으로 침투에 의한 함수시 강도저감에 대한 연구를 시행하였다. 함수에 의한 강도저감은 암종에 관계없이 암석강도에 지배된다는 사실을 확인하였다. 강도가 약한 암일수록 강도저감 민감도가 예민함을 알 수 있다. 강도에 따라 0.5%의 함수비에 50% 내외의 강도 저감현상이 발생하는 일은 매우 흔하게 관찰된다. 대부분의 암석은 포화함수비의 1/4~1/2의 포화에서 파괴가 일어난다는 사실도 확인할 수 있었다. 함수시 암석강도의 약화는 교질물질의 접착강도 약화와 용탈에 의한 것으로 사료된다.

• Journal of Korean Neurosurgical Society
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• 제56권3호
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• pp.200-205
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• 2014

Objective : To prove the extents and details of cervical degeneration after anterior microforaminotomy (AMF) with 6-years follow-up. Methods : A retrospective study of 24 patients, underwent single-level AMF, was performed. Clinical and radiologic data were analyzed with office charts, questionaires, and picture achieving and communication system images. Results : According to Odom's criteria, 91.6% achieved favorable outcome. The mean visual analog scale score was improved from 8.6 to 3, and the mean neck disability index was improved from 27.9 to 7.3 (p<0.01). Eighteen cases (75%) showed disc height (DH) decrease. The disc invasion was correlated with DH decrease (p<0.05). The disc height decrease correlated with static, dynamic changes of shell angle and spur formation (p<0.05). Any radiological parameters did not affect the clinical outcome. Conclusion : AMF is an effective technique for treating unilateral cervical radiculopathy. It showed excellent surgical outcomes even in long-term follow-ups. However, a decrease in DH occurred in a considerable number of patients. Disc invasion during surgery may be the trigger of sequential degeneration.

• Bulletin of the Korean Chemical Society
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• 제17권11호
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• pp.1045-1052
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• 1996

The effects of G-T mismatches on thermal stability, the base-pair lifetime and the global structure of a d(GCGTGCGC)2 duplex were studied by using 1H NMR, UV and CD spectroscopy. The existence of G-T mismatches was found to cause a noticeable change in the chemical environment of imino protons associated with significant decrease in the base-pair lifetime at the mismatched site as well as in thermal stability of the duplex itself. The melting transition of d(GCGTGCGC)2 was not cooperative at all at 100 mM or lower concentration of NaCl, but became cooperative at 500 mM or higher NaCl concentration. The melting temperature (Tm) of this duplex was 32℃ at 500 mM concentration of NaCl, which is much lower than that of d(GCGCGCGC)2 at the same NaCl concentration. This suggests that the decrease in stability may be ascribed to the decrease in the base-pair lifetime and the deviation from the normal structure due to the G-T mismatches. Adding berenil to d(GCGTGCGC)2 caused no observable change in the global structure but the large decrease in the base-pair lifetime and the stability of the duplex.

• 한국농림기상학회:학술대회논문집
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• 한국농림기상학회 2011년도 학술발표회
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• pp.7-10
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• 2011

The semi-arid and arid regions comprise almost 40 percent of the world's land surface. The low and erratic precipitation pattern is the single most significant contributor for limiting crop production in such regions where rainfall is the source for surface, soil and ground water. In a changing climate, the semi-arid and arid regions would increasingly face the challenge of water scarcity. According to the relevant literature; under the assumption of a doubling of the current atmospheric CO2 concentration, irrigation demand was estimated to increase for wheat and to decrease for second crop maize in a Mediterranean environment of Turkey in the 2070s. Crop evapotranspiration would decrease due to stomata closure. Reference evapotranspiration and potential soil evaporation were projected to increase by 8.0 and 7.3%, respectively, whereas actual soil evaporation was predicted to decrease by 16.5%. Drainage losses below 90 cm soil depth were found to decrease mainly due to lesser rainfall amount in the future.

• 한방안이비인후피부과학회지
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• 제15권2호
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• pp.200-209
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• 2002

Visual acuity Decrease is one of the most common symptoms of adolescents. Acupuncture method has been used for improvement of visual acuity from ancient period. But it is not sufficent to recognize underlying causes and predisposing factors of visual acuity decrease. So we investigate the common causes and factors on myopia outpatients group. We researched 992 outpatients who were treated at Department of Acupuncture & Moxibustion, National Medical Center from June 2001 to May 2002. The outpatients were classified into several groups according to visual acuity and age. Common predisposing factors of visual acuity decrease were assessed through questionnaires based on the Classics of the traditional oriental medical bibliography. The results are as follows; age distribution is 52.9$\%$ for female, 47.1$\%$ for male. The predisposing factors were ranked as poor posture(66.9$\%$), unbalanced diet(57.2$\%$), heredity(53.8$\%$), irregular diet habit(51.3$\%$) and so on. These results playa role as preliminary data in recongnition of myopia in the view of oriental medicine.

• 한방안이비인후피부과학회지
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• 제16권1호
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• pp.112-129
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• 2003

Introduction and Objectives : Applying the saingheylyunbooemgami(SY) extract on to the atopic dermatitis(AD) is to study change of external dermal formation, change of leukocytes in vasculature, change of lipid formation in stratum corneum and distribution of ceramide and this study is done through forcing injury to rat's back skin which are lipid protect formation in stratum corneum. Materials and Methods : The AD which caused intentionally using the external application on the rat's back skin was used the SY. The change of leukocytes in vasculature has been identified through optima 5.2 and student t-test and the results were made into dermal foramtion graph. Results : After dispensing SY extract into the AD, the dermal injury was decreased, Especially, recover of lipid protection formation which include lipid and ceramide in stratum corneum is suppressing acute inflammation that some factors are PKC, TNF-${\alpha}$, lL-12B which controled the secretion of relating inflammatory cytokine, also went onto decrease of angiogenesis, and the decrese of degranulated mast cell. In addition, the decrease of epithelial injury also caused the growth of cell to decrease in stratum basale and cytoclasis. In the vasculature. the leukocytes were also decreased and it could relate to decrease AD. Conclusions : Thus. SY has effect on AD suppressing the dermal injury through recovering of lipid protection formation in stratum corneum.

• Archives of Pharmacal Research
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• 제13권3호
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• pp.233-239
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• 1990

The efect of acute renal failure (ARF) on the pharmacokinetics o sulfobromophthalein (BSP) was investigated in order to elucidate if renal failure modifies the hepatic metabolism of drugs. ARF was induced by intravenous (iv) injection of uranyl nitrate (UN) to rats (5 mg/kg) five days before the experiment. Area under the plasma concentration-time curve (AUC)of BSP after portal vein (pv) injection increased by 2-fold and total body clearance ($CL_1$) decreased one half (p <0.01) in UN-induced ARF (UN-ARF) rate compared to the control rats. But the plasma disappearance of BSP after iv injection did not differ significantly between control and UN-ARF rats. Since BSP is excreted via the liver, $CL_1$ represented the approximate hepatic clearance of BSP. Therefore, the decrease in $CL_1$ represented the approximate hepatic clearance of BSP. Therefore, the decrease in $CL_1$ represents a decrease in hepatic intrinsic clearance ($CL_{int}$) for BSP since plasma free fraction ($f_p$) of BSP was not affected by UN-ARF. The content of hepatic cytoplasmic Y-protein, which catalyzes BSP-glutathione conjugation and limits the trasfer of BSP from blood to bile, increased significantly (p < 0.01), however its binding activity (BA) for BSP was decreased significantly (p <0.01) by UN-ARF. The decrease in $CL_{int}$might have some correlation with the changed characteristics of hepatic Y-protein, specifically its decreased BA for BSP.

• Asian Pacific Journal of Cancer Prevention
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• 제14권4호
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• pp.2477-2481
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• 2013

Aims and Background: The purpose of the research was to study the prognostic value of tumor 18F-FDG PET-based parameters in neoadjuvant chemoradiation for patients with squamous esophageal carcinoma. Methods: Sixty patients received chemoradiation therapy followed by esophagectomy and two 18FDG-PET examinations at pre- and post-radiation therapy. PET-based metabolic-response parameters were calculated based on histopathologic response. Linear regression correlation and Cox proportional hazards models were used to determine prognostic value of all PET-based parameters with reference to overall survival. Results: Sensitivity (88.2%) and specificity (86.5%) of a percentage decrease of SUVmax were better than other PET-based parameters for prediction of histopathologic response. Only percentage decrease of SUVmax and tumor length correlated with overall survival time (linear regression coefficient ${\beta}$: 0.704 and 0.684, P<0.05). The Cox proportional hazards model indicated higher hazard ratio (HR=0.897, P=0.002) with decrease of SUVmax compared with decrease of tumor size (HR=0.813, P=0.009). Conclusion: Decrease of SUVmax and tumor size are significant prognostic factors in chemoradiation of esophageal carcinoma.