• Journal of the Korean Society for information Management
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• v.30 no.4
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• pp.111-131
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• 2013

This study describes the meaning of and the formula for Kor-$h_T$, which is a modified index built on the tapered h-index by applying 'the ranking according to the number of citations of journals'. This study evaluated the de-duplication rate of index values of Kor-$h_T$ and analyzed the change in the correlation between the index values and evaluation elements using the Korea Citation Index data from 2008 to 2010. Kor-$h_T$ is compared with h-index, tapered h-index, and IF. As a result, Kor-$h_T$ appeared to be superior to other indexes on de-duplication rate. It is also shown that there is a very strong positive correlation between the evaluation elements, the number of citations and the number of articles of journals, and the index values of Kor-$h_T$.

• Clinical and Experimental Pediatrics
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• v.52 no.5
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• pp.603-606
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• 2009

The Pierre Robin sequence (PRS) is the nonrandom association of micrognathia, cleft palate, and glossoptosis, leading to respiratory and feeding difficulties that appear neurogenic rather than mechanical in causation. Genetic determinants are thought to underlie this functional and morphological entity, based on the existence of Mendelian syndromes with PRS. Here, we demonstrate the association of PRS with trisomy 8p due to duplication of a segment as the karyotype 46,XX,dup(8)(p21.3p23.1) and confirm the additional materials as chromosome 8 via whole chromosome paint probes. Our observation supports the hypothesis regarding a genetic basis for nonsyndromic PRS, strengthens the possible genetic association with isolated cleft palate, and provides a candidate PRS locus in chromosomal region 8(p21.3p23.1).

• Bulletin of the Korean Mathematical Society
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• v.49 no.5
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• pp.989-996
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• 2012

Let R be a commutative Noetherian ring and let I be an ideal of R. In this paper we study the amalgamated duplication ring $R{\bowtie}I$ which is introduced by D'Anna and Fontana. It is shown that if R is generically Cohen-Macaulay (resp. generically Gorenstein) and I is generically maximal Cohen-Macaulay (resp. generically canonical module), then $R{\bowtie}I$ is generically Cohen-Macaulay (resp. generically Gorenstein). We also de ned generically quasi-Gorenstein ring and we investigate when $R{\bowtie}I$ is generically quasi-Gorenstein. In addition, it is shown that $R{\bowtie}I$ is approximately Cohen-Macaulay if and only if R is approximately Cohen-Macaulay, provided some special conditions. Finally it is shown that if R is approximately Gorenstein, then $R{\bowtie}I$ is approximately Gorenstein.

• Animal cells and systems
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• v.4 no.2
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• pp.145-150
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• 2000

Retinoic acid (RA) evokes pattern duplication in the regenerating salamander limb. Interestingly, it also enhances dedifferentiation in the regenerate by the morphological, histological and biochemical criteria. To examine whether there is any correlation between the RA-evoked pattern duplication and de novo protein synthetic profile in the regenerating salamander limb, especially during dedifferentiation, we analyzed stage-specific protein synthesis pattern in the normal and RA-treated regenerating limbs by metabolic labeling followed by two-dimensional gel electrophoresis. In the regenerating limbs without RA treatment, a few hundred kinds of proteins were found to be synthesized at the stage of wound healing and the total number of protein synthesized increased greatly as regeneration proceeded. The same trend was also observed in the RA-treated regenerating limbs. Interestingly, some protein spots were noted to be either newly synthesized or highly expressed by the RA treatment especially at the stage of dedifferentiation. The results shows that the enhancement of dedifferentiation state after the RA treatment correlates well with the protein synthesis profile, and suggest that those proteins are important for the RA-evoked pattern duplication in the regenerating limbs of salamander.

• Journal of Genetic Medicine
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• v.16 no.1
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• pp.15-18
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• 2019

SHORT syndrome is an extremely rare congenital condition due to a chromosomal mutation of the PIK3R1 gene found at 5q13.1. SHORT is a mnemonic representing six manifestations of the syndrome: (S) short stature, (H) hyperextensibility of joints and/or inguinal hernia, (O) ocular depression, (R) Rieger anomaly, and (T) teething delay. Other key aspects of this syndrome not found in the mnemonic include lipodystrophy, triangular face with dimpled chin (progeroid facies, commonly referred to as facial gestalt), hearing loss, vision loss, insulin resistance, and intrauterine growth restriction (IUGR). 3q duplication syndrome is rare syndrome that occurs due to a gain of function mutation found at 3q25.31-33 that presents with a wide array of manifestations including internal organ defects, genitourinary malformations, hand and foot deformities, and mental disability. We present a case of a 2 year and 3 month old male with SHORT syndrome and concurrent 3q duplication syndrome. The patient presented at birth with many of the common manifestations of SHORT syndrome such as bossing of frontal bone of skull, triangular shaped face, lipodystrophy, micrognathia, sunken eyes, and thin, wrinkled skin (progeroid appearance). Additionally, he presented with findings associated with 3q duplication syndrome such as cleft palate and cryptorchidism. Although there is no specific treatment for these conditions, pediatricians should focus on referring patients to various specialists in order to treat each individual manifestation.

• KIISE Transactions on Computing Practices
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• v.21 no.3
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• pp.183-191
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• 2015

Recent developments in IT have made real-time ECG monitoring possible, and this represents a promising application for the emerging HL7 standard for the exchange of clinical information. However, applying the HL7 standard directly to real-time ECG monitoring causes problems, because the partial duplication of data within an HL7 message increases the amount of data to be transmitted, and the time taken to process it. We reduce these overheads by Feature Scaling, by standardizing the range of independent variables or features of data, while nevertheless generating HL7-compliant messages. We also use a De-Duplication algorithm to eliminate the partial repetition of the OBX field in an HL7 ORU message. Our strategy shortens the time required to create messages by 51%, and reduces the size of messages by 1/8, compared to naive HL7 coding.

• Clinical and Experimental Pediatrics
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• v.48 no.12
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• pp.1389-1389
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• 2005

The long arm duplication of chromosome 3 was reported for the first time in 1966 by Falek et al., and Hirschhorn et al. came to identify the duplication of 3q21${\rightarrow}$qter region in 1973. In most cases of duplication 3q syndrome patients, pure duplication of 3qter is believed to be rare and is often reported accompanied with deletion of another segment of the chromosome. Approximately 75 percent of parents of the patient in the meantime have been demonstrated to have unbalanced translocations or inversions of the chromosome. Partial deletion of the distal part of the short arm of chromosome 3 was first reported by Verjaal and De Nef in 1978 and terminal deletion of chromosome 3 (3p25-qter) has been observed in most cases. In karyotyping of chromosomes of immature infants showing the manifestations of flat occiputs, low set ears, hypertelorism, broad nasal roots, thin lips, web necks, hypotonia, hypertrichosis skin, cryptorchidism etc, we experienced a case diagnosed as 46,XY, rec(3)dup(3)(q21)del(3)(p25)inv(3)(p25q21).

• Journal of the Institute of Electronics and Information Engineers
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• v.50 no.4
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• pp.117-123
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• 2013

In the recent cloud storage environment, the amount of SSD (Solid-State Drive) replacing with the traditional hard disk drive is increasing. Management of SSD for its space efficiency has become important since SSD provides fast IO performance due to no mechanical movement whereas it has wearable characteristics and does not provide in place update. In order to manage space efficiency of SSD, data de-duplication technique is frequently used. However, this technique occurs much overhead because it consists of data chunking, hasing and hash matching operations. In this paper, we propose new data de-duplication method using PRAM cache. The proposed method uses hierarchical hash tables and LRU(Least Recently Used) for data replacement in PRAM. First hash table in DRAM is used to store hash values of data cached in the PRAM and second hash table in PRAM is used to store hash values of data in SSD storage. The method also enhance data reliability against power failure by maintaining backup of first hash table into PRAM. Experimental results show that average writing frequency and operation time of the proposed method are 44.2% and 38.8% less than those of existing data de-depulication method, respectively, when three workloads are used.

• Clinical and Experimental Pediatrics
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• v.55 no.3
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• pp.107-110
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• 2012

Partial trisomy 3p results from either unbalanced translocation or $de$ $novo$ duplication. Common clinical features consist of dysmorphic facial features, congenital heart defects, psychomotor and mental retardation, abnormal muscle tone, and hypoplastic genitalia. In this paper, we report a case of partial trisomy 3p with rare clinical manifestations. A full-term, female newborn was transferred to our clinic. She had cleft lip-plate, dysgenesis of the corpus callosum, patent ductus arteriosus, pulmonary hypertension, and severe right-sided hydronephrosis, associated with ureteropelvic junction obstruction. Cytogenetic investigation revealed partial trisomy 3p; 46,XX,der(4)t(3;4)(p21.1;p16). The karyotype of her father showed a balanced translocation, t(3;4)(p21.1;p16). Therefore, the size of duplication can be an important factor.

• Journal of Genetic Medicine
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• v.12 no.1
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• pp.49-56
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• 2015

We herein report an analysis of a female baby with a de novo dup(10p)/del(10q) chromosomal aberration. A prenatal cytogenetic analysis was performed owing to abnormal ultrasound findings including a choroid plexus cyst, prominent cisterna magna, and a slightly medially displaced stomach. The fetal karyotype showed additional material attached to the terminal region of chromosome 10q. Parental karyotypes were both normal. At birth, the baby showed hypotonia, upslanting palpebral fissures, a nodular back mass, respiratory distress, neonatal jaundice and a suspicious polycystic kidney. We ascertained that the karyotype of the baby was 46,XX,der(10)($pter{\rightarrow}q26.3::p11.2{\rightarrow}pter$) by cytogenetic and molecular cytogenetic analyses including high resolution GTG-and RBG-banding, fluorescence in situ hybridization, comparative genomic hybridization, and short tandem repeat marker analyses. While almost all reported cases of 10p duplication originated from one of the parents with a pericentric inversion, our case is extraordinarily rare as the de novo dup(10p)/del(10q) presumably originated from a rearrangement at the premeiotic stage of the parental germ cell or from parental germline mosaicism.