• Investigative Magnetic Resonance Imaging
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• v.16 no.1
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• pp.40-46
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• 2012

Purpose : To investigate the feasibility of in vivo proton magnetic resonance spectroscopy (MRS) for evaluation of lung cancer. Materials and Methods: This prospective study was approved by the institutional review board of our hospital and informed consent was obtained in all patients. Ten patients (7 men, 3 women; mean age, 64.4) with pathologicallyproven lung cancer (mean, 56.8 mm; range, 44-77 mm) were enrolled to 1.5 T MRS using a single-voxel respiration-triggered point-resolved spectroscopic sequence. Technical success rate and the reason of technical failure, if any, were investigated. Results: Out of 10 lung cancers, analyzable MRS spectra were obtained in 8 tumors (technical success rate, 80%). Two MRS datasets were not able to be analyzed due to serious baseline distortion. Choline and lipid signals were detected as major metabolites in analyzable MRS spectra. Conclusion: In vivo proton MRS method using a single-voxel respiration-triggered point-resolved spectroscopic sequence is feasible in obtaining the MR spectra of lung cancer because these spectra were analyzable and high success rate was shown in our study although there was the limitation of small patient group.

• Journal of the Institute of Electronics and Information Engineers
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• v.53 no.6
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• pp.110-121
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• 2016

The primary aim of the color constancy algorithm is to estimate illuminant chromaticity. There are various statistical-based, learning-based and combinational-based color constancy algorithms already exist. However, the statistical-based algorithms can only perform well on images that satisfy certain assumptions, learning-based methods are complex methods that require proper preprocessing and training data, and combinational-based methods depend on either pre-determined or dynamically varying weights, which are difficult to determine and prone to error. Therefore, this paper presents a new optimization based illuminant estimation method which is free from complex preprocessing and can estimate the illuminant under different environmental conditions. A strong color cast always has an odd standard deviation value in one of the RGB channels. Based on this observation, a cost function called the degree of illuminant tinge(DIT) is proposed to determine the quality of illuminant color-calibrated images. This DIT is formulated in such a way that the image scene under standard illuminant (d65) has lower DIT value compared to the same scene under different illuminant. Here, a swarm intelligence based particle swarm optimizer(PSO) is used to find the optimum illuminant of the given image that minimizes the degree of illuminant tinge. The proposed method is evaluated using real-world datasets and the experimental results validate the effectiveness of the proposed method.

• Korean Journal of Remote Sensing
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• v.28 no.4
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• pp.449-458
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• 2012

Using the MODerate resolution Imaging Spectro-radiometer (MODIS) retrieved aerosol optical thickness (AOT) along with ground measurements of PM2.5 mass concentration, we assessed local air quality over Dukjuk and Jeju island and estimated possibility of satellite derived PM2.5 during nine intensive observation periods in 15 October 2005 - 24 October 2007. Averaged PM2.5 mass concentrations showed relatively variable as $25.61{\pm}22.92{\mu}g/m^3$ at Dukjuk and $17.33{\pm}10.79{\mu}g/m^3$ at Jeju. The maximum values of $188.89{\mu}g/m^3$ (Dukjuk) and $50.46{\mu}g/m^3$ (Jeju) were recorded during Asian dust storm day. Similarly, the maximum values of MODIS AOT were found as 3.73 (Gosan) and 1.14 (Jeju). Averaged MODIS AOTs at Dukjuk ($0.79{\pm}0.81$) were larger than that at Jeju ($0.42{\pm}0.24$). An empirical relationship between MODIS AOT and PM2.5 mass was obtained and results show that there was a good correlation between satellite and ground based values with a linear correlation coefficient of 0.85 at Dukjuk. The result clearly demonstrates that satellite derived AOT is a good surrogate for monitoring PM air quality over study area. However, meteorological and other ancillary datasets are necessary to further apply satellite data for air quality research.

• Asian-Australasian Journal of Animal Sciences
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• v.31 no.6
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• pp.791-797
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• 2018

Objective: Trimethylation of histone 3 (H3) at 4th lysine N-termini (H3K4me3) in gene promoter region was the universal marker of active genes specific to cell lineage. On the contrary, coexistence of trimethylation at 27th lysine (H3K27me3) in the same loci-the bivalent H3K4m3/H3K27me3 was known to suspend the gene transcription in germ cells, and could also be inherited to the developed stem cell. In galline species, throughout example of H3K4m3 and H3K27me3 ChIP-seq analysis was still not provided. We therefore designed and demonstrated such procedures using ChIP-seq and mRNA-seq data of chicken follicular mesenchymal cells and male germ cells. Methods: Analytical workflow was designed and provided in this study. ChIP-seq and RNA-seq datasets of follicular mesenchymal cells and male germ cells were acquired and properly preprocessed. Peak calling by Model-based analysis of ChIP-seq 2 was performed to identify H3K4m3 or H3K27me3 enriched regions ($Fold-change{\geq}2$, $FDR{\leq}0.01$) in gene promoter regions. Integrative genomics viewer was utilized for cellular retinoic acid binding protein 1 (CRABP1), growth differentiation factor 10 (GDF10), and gremlin 1 (GREM1) gene explorations. Results: The acquired results indicated that follicular mesenchymal cells and germ cells shared several unique gene promoter regions enriched with H3K4me3 (5,704 peaks) and also unique regions of bivalent H3K4m3/H3K27me3 shared between all cell types and germ cells (1,909 peaks). Subsequent observation of follicular mesenchyme-specific genes-CRABP1, GDF10, and GREM1 correctly revealed vigorous transcriptions of these genes in follicular mesenchymal cells. As expected, bivalent H3K4m3/H3K27me3 pattern was manifested in gene promoter regions of germ cells, and thus suspended their transcriptions. Conclusion: According the results, an example of chicken H3K4m3/H3K27me3 ChIP-seq data analysis was successfully demonstrated in this study. Hopefully, the provided methodology should hereby be useful for galline ChIP-seq data analysis in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.325-331
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• 2020

Even though numerous studies on the relationship between high-performance work systems (HPWSs) and organizational performance have been conducted over the past three decades, empirical evidence is still lacking in the aspects of context and performance. Thus, this study aims to investigate how HPWSs influence organizational performance, especially innovation performance as a key factor to increase the organization's sustainability. In addition, this study examines how human competency and customer service competency as crucial conditions to facilitate organizational innovation moderate the relationship between HPWSs and organizational performance. To examine these hypotheses, this study used Human Corporate Capital Panel datasets. The results of longitudinal analyses show that HPWSs positively affected organizational performance, and the two competencies strengthened the positive main effect, as we expected. In the discussion parts, this study suggests implications and limitations.

• Geophysics and Geophysical Exploration
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• v.23 no.4
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• pp.230-242
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• 2020

We performed a magnetotelluric (MT) survey to delineate the geological structures below the depth of 20 km in the Gyeongju area where an earthquake with a magnitude of 5.8 occurred in September 2016. The measured MT data were severely distorted by electrical noise caused by subways, power lines, factories, houses, and farmlands, and by vehicle noise from passing trains and large trucks. Using machine-learning methods, we classified the MT time series data obtained near the railway and highway into two groups according to the inclusion of traffic noise. We applied three schemes, stochastic gradient descent, support vector machine, and random forest, to the time series data for the highspeed train noise. We formulated three datasets, Hx, Hy, and Hx & Hy, for the time series data of the large truck noise and applied the random forest method to each dataset. To evaluate the effect of removing the traffic noise, we compared the time series data, amplitude spectra, and apparent resistivity curves before and after removing the traffic noise from the time series data. We also examined the frequency range affected by traffic noise and whether artifact noise occurred during the traffic noise removal process as a result of the residual difference.

• KIPS Transactions on Computer and Communication Systems
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• v.9 no.10
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• pp.239-246
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• 2020

In the medical field where artificial intelligence technology is introduced, research related to clinical decision support system(CDSS) in relation to diagnosis and prediction is actively being conducted. In particular, medical imaging-based disease diagnosis area applied AI technologies at various products. However, medical imaging data consists of inconsistent data, and it is a reality that it takes considerable time to prepare and use it for research. This paper describes a one-stop AI learning platform for converting to medical image standard R_CDM(Radiology Common Data Model) and supporting AI algorithm development research based on the dataset. To this, the focus is on linking with the existing CDM(common data model) and model the system, including the schema of the medical imaging standard model and report information for multi-center research based on DICOM(Digital Imaging and Communications in Medicine) tag information. And also, we show the execution results based on generated datasets through the AI learning platform. As a proposed platform, it is expected to be used for various image-based artificial intelligence researches.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.41 no.2
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• pp.23-32
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• 2004

The query optimizer's important task while a query is invoked is to estimate the fraction of records in the databases that satisfy the given query condition. The query result size estimation in spatial databases, like relational databases, proceeds to partition the whole input into a small number of subsets called “buckets” and then estimate the fraction of the input in the buckets. The accuracy of estimation is determined by the difference between the real data counts and approximations in the buckets, and is dependent on how to partition the buckets. Existing techniques for spatial databases are equi-area and equi-count techniques, which are respectively analogous in relation databases to equi-height histogram that divides the input value range into buckets of equal size and equi-depth histogram that is equal to the number of records within each bucket. In this paper we propose a new partitioning technique that determines buckets according to the maximal difference of area which is defined as the product of data ranges End frequencies of input. In this new technique we consider both data values and frequencies of input data simultaneously, and thus achieve substantial improvements in accuracy over existing approaches. We present a detailed experimental study of the accuracy of query result size estimation comparing the proposed technique and the existing techniques using synthetic as well as real-life datasets. Experiments confirm that our proposed techniques offer better accuracy in query result size estimation than the existing techniques for space query size, bucket number, data number and data size.

• Korean Journal of Food Science and Technology
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• v.51 no.6
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• pp.543-550
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• 2019

In this study, volatile compounds in 13 aged and 3 commercial rice-distilled soju samples were isolated by headspace solid phase microextraction (HS-SPME) and analyzed by gas chromatography-mass spectrometry (GC-MS). A total of 85 volatile components including 35 esters, 15 alcohols, 5 ketones, 3 aldehydes, 15 miscellaneous, and 14 unknowns were identified. Esters and alcohols were the largest groups among the quantified volatiles. Differences in volatile compounds among the distilled soju samples and possible sample groupings were examined by principal component analysis of the GC-MS datasets. The first and second principal components (PC1 and PC2, respectively) explained 51.94% of the total variation across the 16 samples. The samples aged in oak containers had higher concentrations of ketones, aldehydes, and miscellaneous compounds. In the positive direction of PC1, oak-aged samples were observed, while, pot-aged samples were observed on the far negative side. Furthermore, samples aged for longer periods, such as 18 months, were observed in the positive direction of PC2.

• Journal of Internet Computing and Services
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• v.21 no.4
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• pp.9-16
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• 2020

In the Image processing and computer vision, the problem of reconstructing from one image to another or generating a new image has been steadily drawing attention as hardware advances. However, the problem of computer-generated images also continues to emerge when viewed with human eyes because it is not natural. Due to the recent active research in deep learning, image generating and improvement problem using it are also actively being studied, and among them, the network called Generative Adversarial Network(GAN) is doing well in the image generating. Various models of GAN have been presented since the proposed GAN, allowing for the generation of more natural images compared to the results of research in the image generating. Among them, pix2pix is a conditional GAN model, which is a general-purpose network that shows good performance in various datasets. pix2pix is based on U-Net, but there are many networks that show better performance among U-Net based networks. Therefore, in this study, images are generated by applying various networks to U-Net of pix2pix, and the results are compared and evaluated. The images generated through each network confirm that the pix2pix model with Attention, R2, and Attention-R2 networks shows better performance than the existing pix2pix model using U-Net, and check the limitations of the most powerful network. It is suggested as a future study.