• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.2
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• pp.1-18
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• 2017

Objectives : This review aims to evaluate a risk of bias by risk of bias tool and RoBANS(Risk of Bias Assessment tool for Non-randomized Study) tool for clinical trial papers proving treatment effect of Korean medicines to alopecia and provides the newest reason of effectiveness of herbs to alopecia. Methods : Data were collected through electronic database including NDSL, KISS, KMBASE, Koreantk, OASIS, KoreaMed, KISTI, Pubmed, Cochrane CENTRAL and CINAHL. Two experts in Oriental Medicine assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool and non-randomized controlled trials by RoBANS tool after searching, reviewing and selecting papers. Results : Total number of selected trials is 20 including 4 randomized controlled trial, 13 non-randomized controlled trials and 3 case reports. This study evaluate the risk of bias of 17 papers including 4 randomized controlled trials and 13 non-randomized controlled trials except 3 case reports by risk of bias tool and RoBANS tool. All papers of randomized controlled trials are evaluated unclear for random sequence generation and allocation concealment as there are no word on them. And all papers of non-randomized controlled trials are evaluated unclear for blinding of outcome assessments and relatively low for others. Conclusions : Korean medicine intervention can be an effective for treatment in alopecia. It was evaluated by hair density, thickness and expert panel assessment of photographs and all results are statistically significant. But enhancing levels of evidence, we must try to reduce bias in researches and report a safety, protocol and IRB.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.3
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• pp.1-19
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• 2017

Objectives : This study aimed to validate the effect of herbal medicine intervention to relieve the symptoms of psoriasis using systematic review and meta-analysis and provide the newest reason of effectiveness of Korean medicine to psoriasis. Methods : Data were collected through electronic database including Pubmed, Cochrane CENTRAL, NDSL OASIS, Koreantk. Two experts assessed risk of bias of randomized controlled trials by Cochrane group's Risk of Bias tool after searching, reviewing and selecting papers. Data were analyzed using Review Manager(RevMan) 5.3 and Comprehensive Meta Analysis 2.0. Results : Total number of selected trials was 16 randomized controlled trials. This study evaluated the risk of bias and effectiveness of herbal medicine to psoriasis. There were high frequency uncertain in selection bias, performance bias and detection bias. In this meta-analysis, Korean medicine treatment was more effective than western medicine (ES:0.507, 95%CI:0.147-0.867) and placebo (ES:0.955, 95%CI:0.598-1.312). Conclusions : Herbal medicine intervention can be an effective for treatment in psoriasis. But enhancing levels of evidence, we must try to accumulate clinical researches of herbal medicine to psoriasis in Korea.

• The Journal of the Korea Contents Association
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• v.8 no.9
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• pp.42-54
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• 2008

In recent years, embedded systems have been expanding their application domains from traditional embedded systems such as military weapons, robots, satellites and digital convergence systems such as celluar phones, PMP(Portable Multimedia Player), PDAs(Personal Digital Assistants) to Next Generation Personal Computers(NGPCs) such as eating PCs, wearable computers. The NGPCs are network-based, human-centric digital information devices diverged from the traditional PCs used mainly for document writing, internet searching and database management. Wearable computers with battery capacity and memory size limitations have to use real-time operating systems with small footprints and low power management techniques to provide user's QoS in spite of hardware constraints. In this paper, we have designed and implemented a low-power RTOS (called eRTOS) for wearable computers. The implemented eRTOS has 18KB footprints and the dynamic power management and the device power management schemes are adapted in it. Experimental results with wearable computer applications show that the low power techniques could save energy up to 47 %.

• Journal of the East Asian Society of Dietary Life
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• v.24 no.3
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• pp.335-350
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• 2014

Compared to the large numbers of studies on the diabetes, hyperlipidemia and cancer therpeutic effects of ginseng, the anti-obese effect and mechanisms of ginsengs have not been studied as much. To determine the effects of ginseng on obesity, 14 keywords (ginseng, ginsenoside, obesity, weight, fat, diet, overeat, appetite, lipid, 3T3-L1, adipocyte, food intake, adipogenesis and lipolysis) were combined in searching a database. Fifty-six articles published from 1983 to 2012 as well as 656 patents registered until Aug $17^{th}$, 2012, were screened for anti-obese effects of ginseng. In the classification of experimental methods, 16 papers on 3T3-L1 cells, 38 papers on animals and three papers on human were reviewed. In terms of obese mechanisms of action, the most commonly used biomarkers were in order of lipid profiles > weight change > blood glucose > adipocytokine. Most ginseng studies on obesity focused on AMPK, $PPAR{\gamma}$, GLUT-4, PI3K and SREBP-1. Korean white ginseng extracts and Re repressed the lipogenesis genes such as PPARc2, SREBP-1c, LPL, FAS and DGAT1. However, ginseng or ginsenosides, PD (Rb1) and PT (Re), showed different or contradictory results. Water and ethanol extraction of ginseng showed contradictory effects on the secretion of inflammatory cytokines, wheras IL-6 was repressed by ethanol extracts and TNF-${\alpha}$ repressed by Re in vitro. Based on the literature, further studies on anti-obese mechanisms of ginseng, such as the inflammation-related obesity or cross signals between the adipocytes and the environments, are needed, instead of more studies on its hypolipidemic and hypoglycemic effects.

• The Transactions of the Korea Information Processing Society
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• v.4 no.2
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• pp.491-498
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• 1997

Geographic Infprmation System(GIS)is being apply to extended from specified ppkication to general purpose deu to the omprovement of computing power.As one part of postal Integarated Information Servies, Postalroute Optimication system(PROS) is comprsed of the composed of the shortest pathe genrator for providing fast and shortest route of postal delivery, the ischronal area generator, the boudary relacation generator, GIS engine, road map, and rdelational database , etc.This paper is related to creation algorithm of the shortest path generation (SPAWD;Shortest Path Algorithm With Direction)from PEOS model.To differ from the exsting shortest path generating methods, this paper suggests SPAWD alforithm for searching destinations of fast time between start and destination points with dirdstion.It comapares and analyzes the new algorithm with existion algorithms, and suggests directions of future studies.

• KIPS Transactions on Software and Data Engineering
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• v.3 no.5
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• pp.179-186
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• 2014

Current networks such as social network, web page link, traffic network are big data which have the large numbers of nodes and edges. Many applications such as social network services and navigation systems use these networks. Since big networks are not fit into the memory, existing in-memory based analysis techniques cannot provide high performance. Frontier-Expansion-Merge (FEM) framework for graph search operations using three corresponding operators in the relational database (RDB) context. FEM exploits an index table that stores pre-computed partial paths for efficient shortest path discovery. However, the index table of FEM has low hit ratio because the indices are determined by distances of indices rather than the possibility of containing a shortest path. In this paper, we propose an method that construct index table using high degree nodes having high hit ratio for efficient shortest path discovery. We experimentally verify that our index technique can support shortest path discovery efficiently in real-world datasets.

• Journal of the Ergonomics Society of Korea
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• v.29 no.6
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• pp.925-932
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• 2010

Most of the research on three-dimensional interaction field have showed different accuracy in terms of sensing, mode and method. Furthermore, implementation of interaction has been a lack of consistency in application field. Therefore, this study is to suggest research trends of three-dimensional interaction using meta-analysis. Searching relative keyword in database provided with 153 domestic papers and 188 international papers covering three-dimensional interaction. Analytical coding tables determined 18 domestic papers and 28 international papers for analysis. Frequency analysis was carried out on method of action, element, number, accuracy and then verified accuracy by effect size of the meta-analysis. As the results, the effect size of sensor-based was higher than vision-based, but the effect size was extracted to small as 0.02. The effect size of vision-based using hand motion was higher than sensor-based using hand motion. Therefore, implementation of three-dimensional sensor-based interaction and vision-based using hand motions more efficient. This study was significant to comprehensive analysis of three-dimensional motion recognition for interaction and suggest to application directions of three-dimensional interaction.

• Spatial Information Research
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• v.9 no.2
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• pp.277-290
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• 2001

In 21st century, tourism can's be formed without tourism information systems. Like other cities Kwangju Met. City has managed tourist information system though internet, but it provide tourist only with poor information as text datum and image datum. Therefore tourist can's get the effective and proper tourism information about Kwangju from that system. The purpose of this paper is to develop tourism information system on the basis of geographic information system for providing tourist with effective geographic tourism information. In the first place, spatial database on tourism information about Kwangju was built by 3 stage of areal scope: national scale, provincial scale and city scale. Next, by analyzing existing tourist information system, 4 major system function is developed: viewing tourism map, guiding tourism information, searching tourism information and printing tourism map. By complement of multimedia datum, this system shall be a major tourism resource of Kwangju.

• BMB Reports
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• v.40 no.1
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• pp.72-81
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• 2007

In order to screen the aging related proteins in human normal colon epithelia, the comparative proteomics analysis was applied to get the two-dimensional electrophoresis (2-DE) profiles with high resolution and reproducibility from normal colon epithelial tissues of young and aged people. Differential proteins between the colon epithelia of two age groups were found with PDQuest software. The thirty five differential protein-spots were identified by peptide mass fingerprint (PMF) based on matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS) and database searching. Among them there are sixteen proteins which are significantly up-regulated in the colonic mucosal epithelia of young people group, which include ATP synthase beta chain, electron transfer flavoprotein alpha-subunit, catalase, glutathione peroxidase 1, annexin A2 and heat shock cognate 71 kDa protein, etc.; There are nineteen proteins which are significantly up-regulated in the colonic mucosal epithelia of aged people group, which include far upstream element-binding protein 1, nucleoside diphosphate kinase B, protein disulfide-isomerase precursor and VDAC-2, etc.. The identified differential proteins appear to be involved in metabolism, energy generation, chaperone, antioxidation, signal transduction, protein folding and apoptosis. The data will help to understand the molecular mechanisms of human colon epithelial aging.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.20 no.2
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• pp.119-126
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• 2002

Recently, as advancing the technologies for Web 3D and Virtual Reality, the studies have been progressed actively to provide three dimensional information on the web. Especially, the various applications for providing urban information in 3D space have been developed using EAI(External Authoring Interface) that serves an interface between VRML(Virtual Reality Modeling Language), standard language for embodying virtual reality, and JAVA applet in HTML. In this study, as constructing 3D virtual city information using Digital Map, IKONOS satellite image, VRML and so on, we could provide users which need several information with building location and various urban living information. In addition, applying 3D skills such as texturing, panorama and navigation, users were enabled to perform various route searching and scenery analysis. Finally, to serve urban living information in real time, we designed to search information faster through interfacing database and to update data using ASP(Active Server Page) on web.