• Journal of Science Education
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• v.37 no.1
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• pp.142-156
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• 2013

The purpose of this study was to analyze observation characteristics through eye movement according to cognitive style. For this, developed observation task that can be shown the difference between wholistic cognitive style group and analytic cognitive style group, measured eye movement of university students who has different cognitive style, as given observation task. It is confirmed the difference between two cognitive style groups by analysing gathered statistics and visualization data. The findings of this study were as follows; First, Compared observation sequence and pattern by cognitive style, analytic cognitive style group is concerned with spider first and moving on surrounding environment, whereas wholistic cognitive style group had not fixed pattern as observing spider itself and surrounding area of spider alternately or looking closely on particular part at first. When observing entire feature and partial feature, wholistic cognitive style group was moving on Fixation from outstanding factor without fixed pattern, analytic cognitive style had certain directivity and repetitive investigation. Second, compared the ratio of observation, analytic cognitive style group gave a large part to spider the very thing, wholistic cognitive style group gave weight to surrounding area of spider, and analytic group shown higher concentration on observing partial feature, wholistic cognitive style group shown higher concentration on observing wholistic feature. Wholistic cognitive style group gave importance to partial features in surrounding area, and wholistic feature of spider than analytic cognitive style group, analytic cognitive style group was focus on partial features of spider than wholistic cognitive style group. Through the result of this study, there are differences of observing time, frequency, object, area, sequence, pattern and ratio from cognitive styles. It is shown the reason why each student has varied outcome, from the difference of information following their cognitive style, and the result of this study help to figure out and give direction to what observation fulfillment is suitable for each student.

• The Korean Journal of Physiology
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• v.17 no.2
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• pp.93-101
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• 1983

A possibility whether the appearance of adaptation to cold climate during winter could occur or not in Taegu area was evaluated by comparing the data obtained in winter with that obtained by the same method in summer. Circulatory response was induced by the immersion of one hand in the cold water. The systemic and local responses in the blood circulation from the immersed hand and the unimmersed opposite hand were observed simultaneously. In addition Galvanic skin resistance(GSR) that is influenced by the activity of autonomic nervous system and the vascular tonicity was recorded. The experiment was performed by examining sixty healthy college students in winter and fifty in summer, whose mean age was 21.0, mean weight $60.6{\pm}0.90\;kg(male)$ and $48.3{\pm}0.98\;kg(female)$. The cold stimulus was applied by immersing the left hand into the cold water of $5^{\circ}C$ for 3 minutes, and the response was observed on immersed left hand and unimmersed right hand simultaneously. The observation was made through determining mean blood pressure, heart rate, amplitude of photoelectric capillary pulse (APCP) and GSR. The results obtained are as follows: The mean blood pressure was elevated during the cold stimulation. The increase of blood pressure in summer was more remarkable than in winter. At the recovery period the blood pressure was decreased to the control level in winter but the decrease below the control level was observed in summer. The increase of heart rate in summer was more remarkable than in winter during the cold stimulation. At the recovery period heart rate in both winter and summer was decreased below the control level. During the cold stimulation the APCP was decreased on both hands in winter. However it was more prominent on left hand indicating additional direct cold effect on immersed hand. In summer, the decrease of APCP during immersion was less remarkable than that in winter, but the regain of APCP was faster than that in winter at the recovery period. And the prompt increase of APCP over the control level has been obtained at the 3 minutes of the recovery period. The GSR was remarkably increased on immersed hand but slightly decreased on unimmersed opposite hand during the cold stimulation. Thus the finding on immersed hand indicates that the local direct effect of cold water is more prominent than the systemic effect, where as the finding on unimmersed hand indicates that the circulatory response to painful stress elicited by the cold stimulation is more prominent than cold temperature itself. In summary, it seems that the systemic circulatory response to the local cold stimulation of the one hand is arised more from the secondary elicited pain sensation and less from the low water temperature. On the contrary to the report of Kim et $al^{39)}$, the adaptation phenomena in blood pressure to the relatively mild cold climate in winter was not observed in this study. The difference of circulatory response observed in this study between winter and summer may be due to the difference of the magnitude of subjective sensation of the cold water stimulation by the seasonal changes in air temperature.

• Journal of Animal Science and Technology
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• v.48 no.6
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• pp.881-888
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• 2006

This study was conducted to investigate effects of maternal genetic potential and parity with pre- and postpartum periods on body weights, body condition score (BCS) and blood metabolites in relation to physiological stress and nutritional metabolism in Hanwoo cows. Also, this study was designed to develop effective husbandry technique for Hanwoo cows concerning of pre- and postpartum periods, and to get basic data for it. Forty five cows were allocated into two groups, 24 cows with high maternal genetic potentials and 21 cows with low maternal genetic potentials. The average parity of experimental cows with high and low maternal genetic potentials were 2.83±1.63 and 3.00±1.77, respectively. The growth performances such as body weights, average daily gain (ADG) and BCS were not different between two groups regardless of maternal genetic potential. However, pre- and postpartum periods had effects on the growth performances (p<0.05). Parity had no effects on ADG and BCS (p>0.05), but effect on body weight of cows (p<0.05). The metabolites of physiological stress such as neutrophil, hematocrit and cortisol, and nutritional metabolites such as albumin, blood urea nitrogen (BUN), triglyceride, and non-esterified fatty acid (NEFA) concentrations in blood of cows were affected by pre- and postpartum periods in a large scale, while those were partially affected by maternal genetic potential. However, among the metabolites in blood, only neutrophil and triglylceride concentrations were affected by different parity of cows. Therefore, the present study suggests that nutritional intake and digestion are affected by physiological stress due to the parturition, and it should need to consider different husbandry technique based on the maternal genetic potential, and pre- and postpartum periods of cows.

• Korean Journal of Environmental Agriculture
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• v.8 no.2
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• pp.128-135
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• 1989

To find the effects of solar energy into the rice canopy and its balance on the rice plant growth, a Tongil type rice, Raekyeong and a japonica rice, Koganebare were used with four levels of nitrogen fertilizer application, 6, 10, 14, and 18kg $l0a^{-1}$ in Chigugo, Japan. The micrometerosological data, the solar radiation and absorbed solar radiation by the rice plants, and leaf area index on cardinal growth stage of the rice community were measured. The results are as follows : Raekyeong showed increased LAI by increased nitrogen fertilizer application rates, and larger LAI than Koganebear. 1. There was no difference in total dry weight till 20 days after transplanting regardless of nitrogen levels in the same variety, after that, however, Raekyeong showed higher dry matter productions for the same durations than Koganebare. 2. In early growth stage of transplanting rice, reflection ratio of solar radiation above the crop canogy was about 6%, however, it was increased up to 20% by the increased LAI at heading date. 3. In high levels of nitrogen application plots, LAI were increased so that values were decreased. 4. Relationship between the amount of absorbed radiation by plants and its dry matter production was linearly significant. Higher levels of nitrogen application produced higher dry matter in Raekyeong, however, in lower level, the dry matter production pattern was almost similar between both rice cultivars.

• Journal of Food Hygiene and Safety
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• v.16 no.1
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• pp.21-26
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• 2001

Risk assessment traditionally are conducted on individual chemicals; however, humans are exposed to multiple chemicals in daily life. The organophosphorus (OP) pesticides are considered in a single risk assessment because they act by a common mechanism of toxicity, and there is likely to be expose to multiple OP pesticides simultaneously or sequentially. The OP pesticides act by inhibiting the enzyme acetylcholinesterasc (AChE) and have available extensive database. AChE is widely distributed throughout the body, most importantly in the nervous system. Inhibition of AChE results in accumulation of acetylcholine in the nervous system that results in clinical signs of cholinergic toxicity, including increased salivation and lacrimation, nausea and vomiting, muscle fasciculation, lethargy and fatigue, among others. To conduct an exposure assessment for pesticides in the diet, we need to know the food consumption patterns of the populations, and the pesticide residue levels in the foods that are consumed. This study was conducted to identify cumulative dietary risk due to multiple OP pesticides that can be exposed through various foods. Total 22 food samples including cereals, vegetables and fruits were collected randomly two times from food markets in several sites (4 cities). The subjected foods were selected by regarding of highly consumed foods to general Korean people. The 12 OP pesticides including Acephate, Azinphos-methyl, Chlorpyrifos, and Diazinon were monitored. For the exposure assessment, general adult group of 60 kg body weight was regarded as target population and food consumption data suggested by Lee et al. (2000) were used as consumed value of individual food. Analyses of samples for OP pesticides have been carried out according to the multiclass multiresidue analysis method and acephate and methamidophos analysis method of Korea Food Code. In general the levels of OP pesticides found in the food samples were very low or not detected.

• Journal of Food Hygiene and Safety
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• v.30 no.1
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• pp.120-125
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• 2015

The objective of this study is to investigate the effect of MSG on cognitive function and anxiety by the T-maze and elevated-plus-maze test and repeated oral dose toxicity in SD rat of MSG. The rats were treated with MSG of control group, low group (3 g/kg) and high group (5 g/kg) intragastrically for 4 weeks, respectively. We examined the body weight, the clinical signs, T-maze, Elevated-plus-maze, hematological analysis and serum biochemical analysis, we also observed the histopathological changes of liver, kidney in rats. No significant differences in body weights, biochemical analysis and histopathological observations between control and MSG treatment group were found. In the elevated plus maze (EPM), MSG-treatment group has more open arm visited than controls. MSG-treatment group has been more activated in T-maze test. These data indicate the continuous high MSG intake could be increased the anxiety and could be decreased cognitive ability. In conclusion, MSG is physiologically safety, but high MSG intake could be increased the anxiety and could be decreased cognitive ability in juvenile rat.

• Journal of Yeungnam Medical Science
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• v.9 no.2
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• pp.275-287
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• 1992

In order to survey the reality of anxiety and depression among the Koreans residing in China, a study was conducted between January and March of 1991, on the residents of Yun-Kil city, with subjects of 472 Koreans and 479 Chinese. The evaluation was based on the questionairs, named Combined self-rating anxiety depression scale(CADS), distributed among the subjects. ANOVA and t-test were applied for data processing. The results were as follows : There was not significant difference in the mean of total scores between the two groups. The scores of Koreans were $29.70{\pm}7.03$, while those of Chinese were $29.45{\pm}9.01$. The score of the CADS above 50(clinially significant level) was seen in 12(2.54%) Koreans and 21(4.38%) Chinese. The anxiety-depression scores relating to the items of indigestion and decreased appetite, sleep disturbance, apprehension, decreased libido were relatively high among the Koreans. The items appeared low in scores among the Koreans were faintness, fear, suicidal rumination, hopelessness, paresthesias. The highs among the Chinese were facial flushing, anxiousness, dissatisfaction, suicidal rumination. The items appeared low among the Chinese were fear, faintness, paresthesias, weight loss, suicidal rumination. In the comparison of evaluation by items between the two groups, the items placing the Koreans significantly higher over the Chinese are indigestion & decreased appetite, sleep disturbance, apprehension, decreased libido. The Chinese marked significantly higher in facial flushing, anxiousness, dissatisfaction, suicidal rumination. Those in the case of female (p<0.01 respectively), less than twenty years old (p<0.01 respectively), dissatisfied with family relationship(p<0.01 respectively), with past history of psychiatric hospitalization(Koreans p<0.01, Chinese p<0.05), pessimistic toward future, present, past self image(p<0.01 respectively) had significantly higher scores in both groups. In religion, neither group showed significant difference. In religion, neither group showed significant difference. In marital status, the Koreans showed a higher degree of divorce and separation and the Chinese in singleness(p<0.01 respectively). The Korean were higher in illiteracy and the Chinese had more college education(p<0.01 respectively). In place of growth, the Koreans showed not much difference in the areas while more Chinese grew up un large cities(p<0.01). More Koreans lived in the dormitory while the Chinese were engaged more in self-cooking(p<0.01 respectively). In pocket money per mouth, more Koreans were less than 1 dollar while the Chinese were between 7 and 10 dollars(p<0.01 respectively). There were no significant difference between two groups about religion.

• Journal of Pharmaceutical Investigation
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• v.35 no.3
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• pp.179-185
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• 2005

Acebrophylline is a compound produced by salifying ambroxol with theophylline-7 -acetic acid. After acebrophylline administration, the salt splits into these two components which feature a peculiar pharmacokinetic behavior, an adequate ambroxol and a low theophylline-7-acetic acid serum levels. The purpose of the present study was to evaluate the bioequivalence of two acebrophylline capsules, Surfolase (Hyundai Pharm. lnd. Co., Ltd.) and Burophil (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of ambroxol from the two acebrophylline formulations in vitro was tested using KP VIII Apparatus II method with various dissolution media (pH 1.2, 4.0, 6.8 buffer solution and water). Twenty eight healthy male subjects, $23.25{\pm}1.43$ years in age and $64.82{\pm}6.77$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After two capsules containing 100 mg as acebrophylline were orally administered, blood was taken at predetermined time intervals and the concentrations of ambroxol in serum were determined using HPLC with electrochemical detector (ECD). The dissolution profiles of two formulations were similar at all dissolution media. In addition, the pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug Surfolase, were -1.64, -3.33 and -0.92% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 $(e.g., \;log\;0.93{\sim}log\;1.05\;and\;log\;0.88{\sim}log\;1.05$ for $AUC_t$, and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Burophil capsule was bioequivalent to Surfolase capsule.

• Journal of Pharmaceutical Investigation
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• v.36 no.3
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• pp.209-215
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• 2006

Zaltoprofen, (2-(10,11-dihydro-10-oxodibenzo[b,f]thiepin-2-yl)propionic acid) is an NSAID with powerful anti-inflammatory effects as well as an analgesic action on inflammatory pain. The purpose of the present study was to evaluate the bioequivalence of two zaltoprofen tablets, $Soleton^{\circledR}$ (CJ Corp.) and SCD Zaltoprofen (Samchundang Pharmaceutical Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The release of zaltoprofen from the two zatoprofen formulations in vitro was tested using KP Vlll Apparatus ll method with various dissolution media. Twenty six healthy male subjects, $23.2{\pm}2.26$ years in age and$64.7{\pm}8.08$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After a single tablet containing 80 mg as zaltoprofen was orally administered, blood samples were taken at predetermined time intervals and the concentrations of zaltoprofen in serum were determined using HPLC with UV detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Soleton^{\circledR}$ were 6.33, 5.91 and 17.7% for $AUC_t$, $C_{max}$ and untransformed $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (e.g.,log $1.01{\sim}1og\;1.11$ and log $0.928{\sim}1og\;1.18$ for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating SCD Zaltoprofen tablet was bioequivalent to $Soleton^{\circledR}$ tablet.

• Magazine of the Korean Society of Agricultural Engineers
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• v.31 no.3
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• pp.41-56
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• 1989

The purpose of this study is to find out the basic data for irrigation plans of garlic and cucumber during the growing period, such as total amount of evapotranspiration, coefficients of evapotranspiration at each growth stage, the peak stage of evapotranspiration and the maximum evapotranspiraton, optimum irrigation point, total readily available moisture, and intervals of irrigation date. The plots of experiment were arranged with split plot design which were composed of two factors, irrigation point for main plot and soil texture for split plot, and three levels ; irrigation points with pP 1.7-2.1, pP 2.2-2.5, pP 2.6-2.8, for garlic and those with pP 1.9, pF 2.3, pP 2.7, for cucumber, soil textures of silty clay, sandy loam and sandy soil for both garlic and cucumber, with two replications. The results obtained are summarized as follows 1.There was the highest significant correlation between the avapotranspiration of garlic and cucumber and the pan evaporation, beyond all other meteorological factors considered, as mentioned in the previous paper. Therefore, the pan evaporation is enough to be used as a meteorological index measuring the quantity of evapotranspiration. 2.1/10 probability values of maximum total pan evaporation during growing period for garlic and cucumber were shown as 495.8mm and 406.8mm, respectively, and those of maximum ten day pan evaporation for garlic and cucumber, 63.8mm and 69.7mm, respectively. 3.The time that annual maximum of ten day pan evaporation can be occurred, exists at any stage between the middle of May and the late of June(harvest period) for garlic, and at any stage of growing period for cucumber. 4.The magnitude of evapotranspiration and of its coefficient for garlic and cucumber was occurred in the order of pF 1.7-2.1>pF 2.2-2.5>pF 2.6-2.8 and of pF 1.9>pF 2.3>pF2.7 respectively in aspect of irrigation point and of sandy loam>silty clay>sandy soil in aspect of soil texture for both garlic and cucumber. 5.The magnitude of leaf area index was shown in the order of pF 2.2-2.5>pF 1.7-2.1>pF 2.6-2.8 for garlic and of pF 1.9>pF 2.3>pF 2.7 for cucumber in aspect of irrigation point, and of sandy loam>sandy soil>silty clay in aspect of soil texture for both garlic and cucumber. 6.1/10 probability value of evapotranspiration and its coefficient during the growing period for garlic were shown as 391.7mm and 0.79 respectively, while those of cucumber, 423.lmm and 1.04 respectively. 7.The time the maximum evapotranspiration of garlic can be occurred is at the date of thirtieth before harvest period and the time for cucumber is presumed to be at the date of sixtieth to seventieth after transplanting, At that time, 1/10 probability value of ten day evapotranspiration and its coefficient for garlic is presumed to be 65.lmm and 1.02 respectively, while those of cucumber, 94.8mm and 1.36 respectively. 8.In aspect of irrigation point, the weight of raw garlic and cucumber were increased in the order of pF 2.2-2.5>pF 1.7-2.1>pF 2.6-2.8 and of pF 1.9>pF 2.3>pF 2.7 respectively. Therefore, optimum irrigation point for garlic and cucumber is presumed to be pF 2.2-2.5 and pF 1.9 respectively, when the significance of yield between the different irrigation treatments is considered. 9.Except the mulching period of garlic that soil moisture extraction patterns were about the same, those of garlic and cucumber have shown that maximum extraction rate exists at 7cm deep layer at the beginning stage after removing mulching for garlic and at the beginning stage of growth for cucumber and that extraction rates of 21cm to 35cm deep layer are increased as getting closer to the late stage of growth. 10.Total readily available moisture of garlic in silty clay, sandy loam, sandy soil become to be 18.71-24.96mm, 19.08-25.43mm, 10.35- 13.80mm respctively on the basis of the optimum irrigation point with pF 2.2-2.5, while that of cucumber, 11.8lmm, 12.03mm, 6.39mm respectively on the basis of the optimum irrigation point with pF 1.9. 11.The intervals of irrigation date of garlic and cucumber at the growth stage of maximum consumptive use become to be about three and a half days and one and a half days respectively, on the basis of each optimum irrgation point.