• Interaction and multiscale mechanics
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• v.4 no.3
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• pp.207-217
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• 2011

International efforts have focused recently on the development of tungsten surfaces that can intercept energetic ionized and neutral atoms, and heat fluxes in the divertor region of magnetic fusion confinement devices. The combination of transient heating and local swelling due to implanted helium and hydrogen atoms has been experimentally shown to lead to severe surface and sub-surface damage. We present here a computational model to determine the relationship between the thermo-mechanical loading conditions, and the onset of damage and failure of tungsten surfaces. The model is based on thermo-elasticity, coupled with a grain boundary damage mode that includes contact cohesive elements for grain boundary sliding and fracture. This mechanics model is also coupled with a transient heat conduction model for temperature distributions following rapid thermal pulses. Results of the computational model are compared to experiments on tungsten bombarded with energetic helium and deuterium particle fluxes.

• Earthquakes and Structures
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• v.3 no.2
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• pp.117-140
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• 2012

The proposed research includes a comprehensive study on the seismic vulnerability assessment of typical building types, representative of the structural materials, the seismic codes and the construction techniques of Southern Europe. A damage database is created after the elaboration of the results of the observational data obtained from post-earthquake surveys carried out in the area struck by the September 7, 1999 Athens earthquake, a near field seismic event in an extended urban region. The observational database comprises 180.945 buildings which developed damage of varying degree, type and extent. The dataset is elaborated in order to gather useful information about the structural parameters influence on the seismic vulnerability and their correlation to the type and degree of building damages in near field earthquakes. The damage calibration of the observational data was based on label - damage provided by Earthquake Planning and Protection Organization (EPPO) in Greece and referred to the qualitative characterization for the recording of damage in post-earthquake surveys. Important conclusions are drawn on the parameters that influence the seismic response based on the wide homogeneous database which adds to the reliability of the collected information and reduces the scatter on the produced results.

• Structural Engineering and Mechanics
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• v.30 no.2
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• pp.135-146
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• 2008

This study utilizes the fine-tuning and small-digit characteristics of the successive zooming genetic algorithm (SZGA) to propose a method of structural damage detection in a continuum structure, where the differences in the natural frequencies of a structure obtained by experiment and FEM are compared and minimized using an assumed location and extent of structural damage. The final methodology applied to the structural damage detection is a kind of pseudo-discrete-variable-algorithm that counts the soundness variables as one (perfectly sound) if they are above a certain standard, such as 0.99. This methodology is based on the fact that most well-designed structures exhibit failures at some critical point due to manufacturing error, while the remaining region is free of damage. Thus, damage of 1% (depending on the given standard) or less can be neglected, and the search concentrated on finding more serious failures. It is shown that the proposed method can find out the exact structural damage of the monitored structure and reduce the time and amount of computation.

• Journal of Korean Society of Forest Science
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• v.40 no.1
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• pp.25-34
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• 1978

Trial and demonslative reforestations were planted by Korea German Management Project at Ulju district in 1976. The follow results that were investigated at spring time in 1977 showed the different situation of winter damage according to site condition and species. 1. Picea abies was completely dried out in this district and its reason was to be thought as a winter damage by cold-dry wind. 2. Cryptomeria japonica was seriously damaged in comparing with Chamaecyparis obtusa and very seriously damaged on the wind-exposured site. So these species are also unsuitable species like Picea abies in this district. 3. The resistance ranking to winter dry wind damage were Picea, Cryptomeria, Chamaecyparis, ${\times}$ Pinus rigitaeda. Pinus rigida, Larix leptolepis and Alnus hirsuta. The falling leave species like larch in this district during winter were thought in necessary to select as the planting species for almost very little winter damage. 4. ${\times}$ Pinus rigitaeda to be showed as a suitable species in this district were also seriously damaged on exposured site and, Pinus rigida and Larix were also attacked with small damage. The potassium-phosphorus fertilizer dressing plots had a trend to reduce this winter damage until some level. 5. The winter climate can be devided into 10 zone in order to evaluate the right or wrong of suitable on the exotic species. The Yongnam region in eastern side of Sobaik mountain are far drier than the Honam region in western side of Sobaik mountain during winter time. Picea abies, Cryptomeria and Chamaecyparis originated in the high humidity winter climate are to be thought to be more suitable in the Honam region than the Yongnam region. Specially the suitable site of Picea abies should be only found in the region with high humidity and much precipitation except the Yongnam region.

• Journal of the Korea Institute of Military Science and Technology
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• v.12 no.4
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• pp.483-490
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• 2009

In this paper, a novel low-damage silicon nitride passivation for 100nm InAlAs/InGaAs MHEMTs has been developed using remote ICPCVD. The silicon nitride deposited by ICPCVD showed higher quality, higher density, and lower hydrogen concentration than those of silicon nitride deposited by PECVD. In particular, we successfully minimized the plasma damage by separating the silicon nitride deposition region remotely from ICP generation region, typically with distance of 34cm. The silicon nitride passivation with remote ICPCVD has been successfully demonstrated on GaAs MHEMTs with minimized damage. The passivated devices showed considerable improvement in DC characteristics and also exhibited excellent RF characteristics($f_T$of 200GHz).The devices with remote ICPCVD passivation of 50nm silicon nitride exhibited 22% improvement(535mS/mm to 654mS/mm) of a maximum extrinsic transconductance($g_{m.max}$) and 20% improvement(551mA/mm to 662mA/mm) of a maximum saturation drain current ($I_{DS.max}$) compared to those of unpassivated ones, respectively. The results achieved in this work demonstrate that remote ICPCVD is a suitable candidate for the next-generation MHEMT passivation technique.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.07a
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• pp.346-349
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• 2002

High Power and high dose ion implantation is essentially needed to make power MOSFET devices based on SiC wafers, because the diffusivities of the impurities such as Al, N, p, B in SiC crystal are very low. In addition, it is needed high temperature annealing for electrical activation of the implanted species. Due to the very high annealing temperature, the surface morphology after electrical activation annealing becomes very rough. We have found the different surface morphologies between implanted and unimplanted region. The unimplanted region showed smoother surface morphology It implies that the damage induced by high energy ion implantation affects the roughening mechanism. Some parts of Si-C bonding are broken in the damaged layer, s\ulcorner the surface migration and sublimation become easy. Therefore the macrostep formation will be promoted. N-type 4H-SiC wafers, which were Al ion implanted at acceleration energy ranged from 30kev to 360kev, were activated at 1600$^{\circ}C$ for 30min. The pre-activation annealing for damage relaxation was performed at 1100-1500$^{\circ}C$ for 30min. The surface morphologies of pre-activation annealed and activation annealed were characterized by atomic force microscopy(AFM).

• Biomedical Science Letters
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• v.19 no.4
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• pp.310-314
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• 2013

CYP2E1 in the liver has been studied intensively because it is involved in the metabolic activation of xenobiotics. It is inducible by alcohol, so it has been suspected as the cause of cancer in the stomach and lung. The possible role of CYP2E1 has been suggested strongly as causing tissue damage in mice with renal failure. It was also suspected that 5'-flanking region of CYP2E1 gene might be involved with renal failure. So, we investigated polymorphism of restriction enzyme sites within CYP2E1 gene using the PCR-RFLP analysis. PstI and RsaI sites were located at 5'-flanking region and DraI site was located at intron 6. All three types (W/W, W/S, S/S) were observed for these enzymes although each incidence was somewhat different depending the enzyme sites. W/W was prominent for PstI whereas W/S was markedly high for RsaI. Overall, polymorphic incidence in patients was somewhat higher than normal population. This research should facilitate further investigation of CYP2E1 at genetic level as the direct cause of tissue damage in various organs.

• Structural Engineering and Mechanics
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• v.42 no.6
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• pp.799-813
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• 2012

Five two-span reinforced concrete (RC) slabs and seven two-span RC beams were tested under the ISO 834 standard fire with different durations. CFRP strengthening was then applied to some of the specimens after the damaged concrete was removed from the specimens and replaced with polymer mortar. All the specimens were loaded to failure to investigate the influence of fire-damage and the effectiveness of strengthening methods. Test results indicated that the flexural capacities of specimens decrease with the fire duration increases. Moreover, fire exposure had more significant effect on the flexural rigidity than on the bearing capacity of the specimens. After rehabilitation, the bearing capacities of specimens reached or even exceeded that of the reference RC specimen, and the strengthening methods seemed to have limited effect on flexural rigidity recovery. From the analysis of moment redistribution of tested beams, elevated temperature is found having different impacts on sagging moment region and hogging moment region. The damage of RC continuous member is definitely a comprehensive response of different regions.

• Earthquakes and Structures
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• v.25 no.6
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• pp.469-479
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• 2023

A probabilistic seismic damage analysis is an essential procedure to identify seismically vulnerable structures, prioritize the seismic retrofit, and ultimately minimize the overall seismic risk. To assess the seismic risk of multiple structures within a region, a large number of nonlinear time-history structural analyses must be conducted and studied. As a result, each assessment requires high computing resources. To overcome this limitation, we explore a deep learning-based metamodel to enable the prediction of the mean and the standard deviation of the seismic damage distribution of track-on steel-plate girder railway bridges in Korea considering the geometric variation. For machine learning training, nonlinear dynamic time-history analyses are performed to generate 800 high-fidelity datasets on the seismic response. Through intensive trial and error, the study is concentrated on developing an optimal machine learning architecture with the pre-identified variables of the physical configuration of the bridge. Additionally, the prediction performance of the proposed method is compared with a previous, well-defined, response surface model. Finally, the statistical testing results indicate that the overall performance of the deep-learning model is improved compared to the response surface model, as its errors are reduced by as much as 61%. In conclusion, the model proposed in this study can be effectively deployed for the seismic fragility and risk assessment of a region with a large number of structures.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.1
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• pp.47-57
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• 2022

Stiripentol is an anti-epileptic drug for the treating of refractory status epilepticus. It has been reported that stiripentol can attenuate seizure severity and reduce seizure-induced neuronal damage in animal models of epilepsy. The objective of the present study was to investigate effects of post-treatment with stiripentol on cognitive deficit and neuronal damage in the cornu ammonis 1 (CA1) region of the hippocampus proper following transient ischemia in the forebrain of gerbils. To evaluate ischemia-induced cognitive impairments, passive avoidance test and 8-arm radial maze test were performed. It was found that post-treatment with stiripentol at 20 mg/kg, but not 10 or 15 mg/kg, reduced ischemia-induced memory impairment. Transient ischemia-induced neuronal death in the CA1 region was also significantly attenuated only by 20 mg/kg stiripentol treatment after transient ischemia. In addition, 20 mg/kg stiripentol treatment significantly decreased ischemia-induced astrocyte damage and immunoglobulin G leakage. In brief, stiripentol treatment after transient ischemia ameliorated transient ischemia-induced cognitive impairment in gerbils, showing that pyramidal neurons were protected and astrocyte damage and blood brain barrier leakage were significantly attenuated in the hippocampus. Results of this study suggest stiripentol can be developed as a candidate of therapeutic drug for ischemic stroke.