• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.227-241
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• 2004

Objective : This study was performed to investigate neuroprotective effects of Bupleuri Radix against oxidative and ischemic damages. Method : To observe the neuroprotective effects against ischemic damage, ischemic insult was induced by oxygen/glucose deprivation (OGD) on organotypic hippocampal slice cultures (OHSC) from 1 week-old Sprague-Dawley rats. Propidium iodide (PI) fluorescence-stained neuronal dead-cell areas, area percentages and TUNEL-positive apoptotic cells in CA1 and dentate gyrus, and LDH levels in culture media of the OHSC were measured following Bupleuri Radix extract treatment. Result : The following results were obtained: (1) The $5\;{\mu}g/ml$ of Bupleuri Radix treatment demonstrated a significant decrease in PI fluorescence-stained neuronal dead-cell areas and area percentage in CA1 region of the OHSC from 18 hrs to 48 hrs following the OGD. The $50\;{\mu}g/ml$ of Bupleuri Radix treatment was also significant from 6 hrs to 48 hrs following the OGD and was more effective. (2) The 5 and $50\;{\mu}g/ml$ of Bupleuri Radix treatment demonstrated a significant decrease in PI fluorescence-stained neuronal dead-cell areas and area percentage in DG region of the OHSC from 6 hrs to 48 hrs following the OGD. The $50\;{\mu}g/ml$ treatment was more effective than the $5\;{\mu}g/ml$ treatment. (3) Bupleuri Radix treatment demonstrated a significant decrease in TUNEL-positive apoptotic cells in CA1 region (with 5 and $50\;{\mu}g/ml$) and in DG region (with $50\;{\mu}g/ml$) of the OHSC damaged by the OGD. (4) Bupleuri Radix treatment demonstrated a significant decrease in LDH concentrations in culture media of the OHSC damaged by the OGD. Conclusion : These results suggest that Bupleuri Radix has neuroprotective and control effects on inflammatory and immune responses where there has been ischemic damage to the central nervous system.

• Smart Structures and Systems
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• v.15 no.4
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• pp.1121-1137
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• 2015

This study presents probabilistic-based damage identification technique for highlighting damage in metallic structures. This technique utilizes distributed piezoelectric transducers to generate and monitor the ultrasonic Lamb wave with narrowband frequency. Diagnostic signals were used to define the scatter signals of different paths. The energy of scatter signals till different times were calculated by taking root mean square of the scatter signals. For each pair of parallel paths an error function based on the energy of scatter signals is introduced. The resultant error function then is used to estimate the probability of the presence of damage in the monitoring area. The presented method with an autofocusing feature is applied to aluminum plates for method verification. The results identified using both simulation and experimental Lamb wave signals at different central frequencies agreed well with the actual situations, demonstrating the potential of the presented algorithm for identification of damage in metallic structures. An obvious merit of the presented technique is that in addition to damages located inside the region between transducers; those who are outside this region can also be monitored without any interpretation of signals. This novelty qualifies this method for online structural health monitoring.

• Journal of Information Processing Systems
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• v.15 no.6
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• pp.1350-1364
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• 2019

The ice damage occurs frequently in cold and dry region of western China in winter ice period and spring thaw period. In the drift ice condition, it is easy to form different extrusion force or impact force to damage tunnel lining, causing project failure. The failure project could not arrive the original planning and construction goal, giving rise to the water allocation pressure which influences diversion irrigation and farming production in spring. This study conducts the theoretical study on contact-impact algorithm of drift ices crashing diversion tunnel based on the symmetric penalty function in finite element theory. ANSYS/LS-DYNA is adopted as the platform to establish tunnel model and drift ice model. LS-DYNA SOLVER is used as the solver and LS-PREPOST is used to do post-processing, analyzing the damage degrees of drift ices on tunnel. Constructing physical model in the experiment to verify and reveal the impact damage mechanism of drift ices on diversion tunnel. The software simulation results and the experiment results show that tunnel lining surface will form varying degree deformation and failure when drift ices crash tunnel lining on different velocity, different plan size and different thickness of drift ice. The researches also show that there are damages of drift ice impact force on tunnel lining in the thawing period in cold and dry region. By long time water scouring, the tunnel lining surfaces are broken and falling off which breaks the strength and stability of the structure.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.33 no.3
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• pp.231-238
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• 2020

This paper investigates the soundness of porcelain insulators associated with the acoustic emission (AE) technique. The AE technique is a popular non-destructive method that measures and analyzes the burst energy that occurs mainly when a crack occurs in a high-frequency region. Typical AE methods require continuous monitoring with frequent sensor calibration. However, in this study, the AE technique excites a porcelain insulator using only an impact hammer, and it applies a high-pass filter to the signal frequency range measured only in the AE sensor by comparing the AE and the acceleration sensors. Next, the extracted time-domain signal is analyzed for the damage assessment. In normal signals, the duration is about 2ms, the area of the envelope is about 1,000, and the number of counts is about 20. In the damage signal, the duration exceeds 5ms, the area of the envelope is about 2,000, and the number of counts exceeds 40. In addition, various characteristics in the time and frequency domain for normal and damage cases are analyzed using the short-time Fourier transform (STFT). Based on the results of the STFT analysis, the maximum energy of a normal specimen is less than 0.02, while in the case of the damage specimen, it exceeds 0.02. The extracted high-frequency components can present dynamic behavior of crack regions and eigenmodes of the isolated insulator parts, but the presence, size, and distribution of cracks can be predicted indirectly. In this regard, the characteristics of the surface crack region were derived in this study.

• Earthquakes and Structures
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• v.24 no.1
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• pp.37-51
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• 2023

Türkiye has made significant changes and updates in both seismic risk maps and design codes over time, as have other countries with high seismic risk. In this study, the last two seismic design codes and risk maps were compared for the Aegean Region (Western Türkiye) where the earthquake risk has once again emerged with the 2020 Izmir Earthquake (Mw=6.9). In this study, information about the seismicity of the Aegean Region was given. The seismic parameters for all provinces in the region were compared with the last two earthquake risk maps. The spectral acceleration coefficients of all provinces have increased and differentiated with the current seismic hazard map as a result of the design spectra used on a regional basis have been replaced by the geographical location-specific design spectra. In addition, section damage limits were obtained for all provinces within the scope of the last two seismic design codes. Structural analyses for a sample reinforced-concrete building were made separately for each province using pushover analysis. The deformations in the cross-sections were compared with the limit states corresponding to the damage levels specified in the last two seismic design codes for the region. Target displacement requests for all provinces have decreased with the current code. The differentiation of geographical location-specific design spectra both in the last two seismic design code and between provinces has caused changes in section damages and building performance levels. The main aim of this study is to obtain and compare both seismic and structural analysis results for all provinces in the Aegean Region (Western Türkiye).

• Structural Engineering and Mechanics
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• v.48 no.3
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• pp.291-308
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• 2013

Structural health monitoring is crucial to maintain the structural performance safely. Moreover, the Kullback-Leibler divergence (KLD) is applied usually to asset the similarity between different probability density functions in the pattern recognition. In this study, the KLD is employed to detect the damage. However the asymmetry of the KLD is a shortcoming for the damage detection, to overcoming this shortcoming, two other divergences and one statistic distribution are proposed. Then the damage identification by the KLD and its three descriptions from the symmetric point of view is investigated. In order to improve the reliability and accuracy of the four divergences, the gapped smoothing method (GSM) is adopted. On the basis of the damage index approach, the new damage index (DI) for detect damage more accurately based on the four divergences is developed. In the last, the grey relational coefficient and hypothesis test (GRCHT) is utilized to obtain the more precise damage identification results. Finally, a clear remarkable improvement can be observed. To demonstrate the feasibility and accuracy of the proposed method, examples of an isotropic beam with different damage scenarios are employed so as to check the present approaches numerically. The final results show that the developed approach successfully located the damaged region in all cases effect and accurately.

• Structural Engineering and Mechanics
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• v.29 no.3
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• pp.311-325
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• 2008

Noting that damage occurrence of offshore jacket platforms is concentrated in two structural regions that are in the vicinity of still water surface and close to the seabed, a damage detection method by using only partial measurement of vibration in a suspect region was presented in this paper, which can not only locate damaged members but also evaluate damage severities. Then employing an experiment platform model under white-noise ground excitation by shaking table and using modal parameters of the first three modes identified by a scalar-type ARMA method on undamaged and damaged structures, the feasibility of the damage detection method was discussed. Modal parameters from eigenvalue analysis on the structural FEM model were also used to help the discussions. It is demonstrated that the damage detection algorithm is feasible on damage location and severity evaluation for broken slanted braces and it is robust against the errors of baseline FEM model to real structure when the principal errors is formed by difference of modal frequencies. It is also found that Z-value changes of modal shapes also play a role in the precise detection of damage.

• Structural Engineering and Mechanics
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• v.30 no.6
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• pp.699-712
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• 2008

The effectiveness of wavelet transform in detecting delamination damages in multilayered composite beams and plates is studied here. The damaged composite beams and plates are modeled in finite element software ABAQUS and the first few mode shapes are obtained. The mode shapes of the damaged structures are then wavelet transformed. It is observed that the distribution of wavelet coefficients can identify the damage location of beams and plates by showing higher values of wavelet coefficients at the position of damage. The effectiveness of the method is studied for different boundary conditions, damage location and size for single as well as multiple delaminations in composite beams and plates. It is observed that both discrete wavelet transform (DWT) and continuous wavelet transform (CWT) can detect the presence and location of the damaged region from the mode shapes of the structures. DWT may be used to approximately evaluate the size of the delamination area, whereas, CWT is efficient to detect smaller delamination areas in composites.

• Earthquakes and Structures
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• v.3 no.1
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• pp.83-95
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• 2012

Seismic damage and vulnerability of five historical masonry structures surveyed after the 1999 Kocaeli and Duzce, Turkey earthquakes are discussed in this paper. The structures are located in two neighboring cities that have been struck by five very large ($M_s{\geq}7.0$) earthquakes during the $20^{th}$ century alone. Older masonry mosques with arches and domes and their masonry minarets (slender towers) were among the most affected structures in this highly seismic region. While some of the religious and historical structures had virtually no damage, most structures suffered significant damage or collapsed. In the city of Bolu, for example, approximately 600-year-old Imaret, 500-year-old Kadi, 250-year-old Sarachane, and 100-year-old Yildirim Bayezid mosques suffered substantial structural damage after the 1999 earthquakes. Another historical mosque surveyed in Duzce partially collapsed. Most common factors contributing to deterioration of historical structures are also presented. Furthermore, a brief overview of issues associated with analysis and modeling of historical masonry structures is provided.

• Interaction and multiscale mechanics
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• v.4 no.3
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• pp.207-217
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• 2011

International efforts have focused recently on the development of tungsten surfaces that can intercept energetic ionized and neutral atoms, and heat fluxes in the divertor region of magnetic fusion confinement devices. The combination of transient heating and local swelling due to implanted helium and hydrogen atoms has been experimentally shown to lead to severe surface and sub-surface damage. We present here a computational model to determine the relationship between the thermo-mechanical loading conditions, and the onset of damage and failure of tungsten surfaces. The model is based on thermo-elasticity, coupled with a grain boundary damage mode that includes contact cohesive elements for grain boundary sliding and fracture. This mechanics model is also coupled with a transient heat conduction model for temperature distributions following rapid thermal pulses. Results of the computational model are compared to experiments on tungsten bombarded with energetic helium and deuterium particle fluxes.