• KIPS Transactions on Software and Data Engineering
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• v.3 no.1
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• pp.19-30
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• 2014

For the expansion of the Semantic Web, studies in converting the data stored in the relational database into the ontology are actively in process. Such studies mainly use an RDB to RDF mapping model, the model to map relational database components to RDF components. However, pre-proposed mapping models have got different expression modes and these damage the accessibility and reusability of the users. As a consequence, the necessity of the standardized mapping language was raised and the W3C suggested the R2RML as the standard mapping language for the RDB to RDF model. The R2RML has a characteristic that converts only the relational database schema data to RDF. For the same reasons above, the ontology about the relation data between table name and column name of the relational database cannot be added. In this paper, we propose an RDB to RDF mapping system considering semantic relations of RDB components in order to solve the above issue. The proposed system generates the mapping data by adding the RDFS attribute data into the schema data defined by the R2RML in the relational database. This mapping data converts the data stored in the relational database into RDF which includes the RDFS attribute data. In this paper, we implement the proposed system as a Java-based prototype, perform the experiment which converts the data stored in the relational database into RDF for the comparison evaluation purpose and compare the results against D2RQ, RDBToOnto and Morph. The proposed system expresses semantic relations which has richer converted ontology than any other studies and shows the best performance in data conversion time.

• Journal of the Earthquake Engineering Society of Korea
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• v.14 no.5
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• pp.13-22
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• 2010

Masonry infill walls are frequently used as interior partitions and exterior walls in low- or middle- rise RC buildings. In the design and assessment of buildings, the infill walls are usually treated as non-structural elements and they are ignored in analytical models because they are assumed to be beneficial to the structural responses. Therefore, their influences on the structural response are ignored. In the case of buildings constructed in the USA in highly seismic regions, infill walls have a lower strength and stiffness than the boundary frames or they are separated from the boundary frames. Thus, the previously mentioned assumptions may be reasonable. However, these systems are not usually employed in most other countries. Therefore, the differences in the seismic behaviors of RC buildings with/without masonry infill walls, which are ignored in structural design, need to be investigated. In this study, structural analyses were performed for a masonry infilled low-rise RC moment-resisting frame. The infill walls were modeled as equivalent diagonal struts. The seismic behaviors of the RC moment-resisting frame with/without masonry infill walls were evaluated. From the analytical results, masonry infill walls can increase the global strength and stiffness of a structure. Consequently, the interstory drift ratio will decrease but seismic forces applied to the structure will increase more than the design seismic load because the natural period of the structure decreases. Partial damage of the infill walls by the floor causes vertical irregularity of the strength and stiffness.

• The Korea Journal of Herbology
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• v.30 no.6
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• pp.63-68
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• 2015

Objectives : Gastric lesions affect many people around the world and their development are results of the imbalance between destructive and protective factors in the gastric mucosa. Lycium chinense has been widely used as a traditional Korean medicine, it was recently reported that they have potent anti-inflammatory effects in chronic hepatitis models. Therefore, this study aimed to investigate the anti-inflammatory activity of Lycium chinense extract (LCE) on HCl-Ethanol induced gastric lesion mice.Methods : The ICR mice were divided randomly into five groups of six animals each. Group A was normal mice, and group B was treated orally with 0.5 ml 150 mM HCl-60% Ethanol. Mice in group C and D were pre-treatment of LCE (100 mg/kg and 200 mg/kg bodyweight, p.o before HCl/ethanol treatment) and group E was orally administered sucralfate (10 mg/kg).Results : 150mM HCl/60% ethanol-induced gastric mucosal injury mice were ameliorated mucosal damage upon histological evaluation by treatment of LCE. Pre-treatment of LCE attenuated reactive oxidative species (ROS) and produces peroxynitrite (ONOO^-) in stomach tissues. As results of stomach protein analyses, LCE effectively reduce inflammatory-related factors such as cyclooxygenase-2 (COX-2), tumor necrosis factor alpha (TNF-α), inducible nitric oxide synthase (iNOS) and interleukin-6 (IL-6) in gastric lesion mice. In addition, nuclear factor kappa B (NF-κB) and inhibitor of phosphorylation of nuclear factor kappa B (p-IκB) were down-regulated in LCE-administrated gastric lesion mice.Conclusions : Our discovery supports that the therapeutic activity of LCE ameliorate the development of gastric lesion via suppressing the oxidative stress and gastric partial inflammation induced by 150 mM HCl/60% ethanol.

• Korean Journal of Agricultural Science
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• v.32 no.1
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• pp.29-42
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• 2005

During a long journey of agricultural products from the production area to markets, the quality of agricultural products was always affected by some degree of vibration. The vibration input during the transportation may cause serious agricultural product injury, and this damage is particularly severe whenever the vegetable inside package is free to bounce, and is vibrated at its resonant frequency. The objectives of this study were to determine the resonant frequency of the oriental melon and to investigate the relationships between resonant frequency and physical properties of the oriental melon such as mass, volume and major and minor axes. In this study vibration testing device was constructed to determine the vibration response of the oriental melon in frequency ranges of 5 to 150 Hz. The computer program for controlling the vibration shaker and the function generator and measuring the vibration characteristics of the oriental melon was developed. The ranges of resonant frequency and peak acceleration at resonance of the oriental melon were 51 to 73 Hz and 1.24 to 1.92 G-rms, respectively. The resonant frequency and the peak acceleration decreased with the increase of the sample mass, volume, major and minor axes of the oriental melon. Multiple regression models for resonant frequency and peak acceleration of the oriental melon as a function of mass, major axis and minor axis of the sample were developed and analyzed.

• Journal of Korea Water Resources Association
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• v.41 no.3
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• pp.341-351
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• 2008

Since the damage from the torrential rain increases recently due to climate change and global warming, the significance of flood forecasting and warning becomes important in medium and small streams as well as large river. Through the preprocess and main processes for estimating runoff, diverse errors occur and are accumulated, so that the outcome contains the errors in the existing flood forecasting and warning method. And estimating the parameters needed for runoff models requires a lot of data and the processes contain various uncertainty. In order to overcome the difficulties of the existing flood forecasting and warning system and the uncertainty problem, ANFIS(Adaptive Neuro-Fuzzy Inference System) technique has been presented in this study. ANFIS, a data driven model using the fuzzy inference theory with neural network, can forecast stream level only by using the precipitation and stream level data in catchment without using a lot of physical data that are necessary in existing physical model. Time series data for precipitation and stream level are used as input, and stream levels for t+1, t+2, and t+3 are forecasted with this model. The applicability and the appropriateness of the model is examined by actual rainfall and stream level data from 2003 to 2005 in the Tancheon catchment area. The results of applying ANFIS to the Tancheon catchment area for the actual data show that the stream level can be simulated without large error.

• Journal of Biomedical Engineering Research
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• v.20 no.1
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• pp.37-44
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• 1999

Because of bone resorption, wear of ultra-high molecular weight polyethylene(UHMWPE) in total knee arthroplasty has been recognized as a major factor in long-term failure of knee implant. The surface damage and the following harmful wear debris of UHMWPE is largely related to contact stress. Most of the previous studies focused on the contact condition only at the articulating surface of UHMWPE. Recently, contact stress at the metal-backing interface has been implicated as one of major factors in UHMWPE wear. Therefore, the purpose of the is study is to investigate the effect of the contact stress for different thickness, conformity friction coefficient, and flexion degree of the UHMWPE component in total knee system, considering the contact conditions at both interfaces. In this study, a two-dimensional non-linear plane strain finite element model was developed. The results showed that the maximum value of von-Mises stress occurred below the articulating surface and the contact stress was lower for the more conforming models. All-polyethylene component showed lower stress distribution than the metal-backed component. With increased friction coefficient on the tibiofemoral contact surface, the maximum shear stress increased about twofold.

• Journal of Periodontal and Implant Science
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• v.31 no.2
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• pp.277-285
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• 2001

Periodontal disease is characterized by inflammation and subsequent loss and/or damage to tooth-supporting tissues such as bone, cementum,and periodontal ligament. Periodontal ligament and cementum are the key tissues in the initial process of regeneration following periodontal disease. Therefore, studies on cementoblasts, which form cementum are emphasized. It is still unclear which cells cementoblast differentiate from. This study was conducted under the hypothesis that PDL fibroblast can differentiate into either cementoblast or osteoblast depending on the conditions of surrounding tissue. Clinically, with excessive traction force of orthodontic appliances or excessive occlusion hypercementosis is observed, and this has been confirmed histologically. Consequently, activation of cementoblast can be expected in rats when mechanical stimuli are given to PDL fibroblast. Therefore, the purpose of this article is to prove that PDL fibroblast differentiates into cementoblast in rats under mechanical stimuli using histologic and molecular methods. In this study, twenty rats were given hard diet. Ten of them were sacrificed after 1 week, and the others were sacrificed after two weeks. Slides were made from tooth specimen, and they were studied under the microscope. In addition, PDL fibroblast and cementum from the extracted teeth were analyzed with Northern blotting. In histologic examination, as time passed, PDL fibroblast migrated to the dentin side, differentiated into cementoblast, and formed new cementum. In Northern blotting, it was found that mRNA expression of cementoblast-specific proteins such as BSP, OC, OPN, and type I collagen were more prominent in rats sacrificed after 2 weeks of hard-diet than rats sacrificed after 1 week. From these findings we can conclude that PDL fibroblast can differentiate into cementoblast under mechanical stimuli. We think that 'Rat Models' used in this study will be beneficial to future studies regarding cementoblast.

• Journal of the Korea institute for structural maintenance and inspection
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• v.22 no.6
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• pp.37-44
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• 2018

This study proposed the modified weighting values for jointed rock slopes. The studies on deduction of evaluation index and calculation of weighting, development of criteria for evaluation and evaluation models have been conducted through decision making techniques such as the Delphi method and the AHP method by many researchers. Because these decisions making techniques may be less objective, it is necessary to calculate reasonable weighting considering both an objective weighting and a subjective weighting simultaneously. In this study, utilizing the inspection data of jointed rock slopes, an objective weighting that the concept of entropy is applied was calculated. And the subjective weighting values by AHP technique was calculated based on the opinion of experts. And a modified weighting was suggested by combining the two. As a result, it was found that jointed rock slopes have higher weighting in artificial factors and the damage status items. In addition based on the finally suggested weighting (mixed weighting), the revised evaluation criteria could be presented by converting it into the evaluation score (76 points). And it is expected that it could be usefully utilized upon inspections on cutting slopes and safety diagnosis since objective and highly reliable criteria compared to the condition evaluation criteria that are currently used could be presented through the results of the study.

• Journal of Veterinary Clinics
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• v.24 no.3
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• pp.325-330
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• 2007

This study was to determine whether canine model which produce acute permanent joint instability in short period without postoperative exercise have a degenerative changes and also evaluated its suitability as an appropriate animal OA models. Ten skeletally mature beagle dogs underwent a unilateral surgical transection of the cranial cruciate ligament and, the medial collateral ligament as well as a medial meniscectomy. The contra-lateral joint was used as control. After 12 weeks, After 12 weeks, the amount of joint damage, inflammation and biochemical change of synovial fluid was evaluated. Histological analysis showed chondrocyte clone formation, hypertrophy of the cartilage and moderate loss of proteoglycans in the experimental joints compared to control joints. In addition, the synovial inflammation in the experimental joints was observed. Biochemical analysis of SF showed significantly increased MMP (matrix metalloproteinase) -2 and -9 in experimental joints compared to control joints. This canine OA model shows the characteristics of degenerative joint disease, and may have a advantages of reducing the time and cost because postoperative exercise is not needed in this OA model.

• Korean Journal of Medicinal Crop Science
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• v.25 no.4
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• pp.231-237
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• 2017

Background: Cisplatin is one of the most extensively used chemotherapeutic agents for the treatment of cancer, including bladder, and ovarian cancers. However, it has been shown to induce nephrotoxicity, despite being an outstanding anti-cancer drug. In this study, we investigated the protective effect of dopaol ${\beta}$-D-glucoside (dopaol) on cisplatin-induced nephrotoxicity. Methods and Results: To confirm the protective effect of dopaol on cisplatin-induced nephrotoxicity, HK-2 cells were treated with $20{\mu}M$ cisplatin and $80{\mu}M$ dopaol. Cisplatin increased apoptosis, caspase-3 activity and mitochondrial dysfunction; however pretreatment with $80{\mu}M$ dopaol successfully attenuated apoptosis, caspase-3 activity and mitochondrial dysfunction. To evaluate the protective effect dopaol on cisplatin-induced nephrotoxicity in vivo, we used an animal model (balb/c mice, 20 mg/kg, i.p. once/day for 3 day). The results were similar to those obtained using HK-2 cells; renal tubular damage and neutrophilia induced by cisplatin reduced following dopaol injection (10 mg/kg, i.p. once/day for 3 day). Conclusions: These results indicate that dopaol treatment reduced cisplatin-induced nephrotoxicity in vitro and in vivo, and can be used to treat cisplatin-induced nephrotoxicity. However, further studies are required to determine the toxicity high dose dopaol and the signal pathways involved in its mechanism of action in animal models.