• 한국군사과학기술학회지
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• 제3권1호
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• pp.191-197
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• 2000

This paper provides the test results of tracked vehicle at each driving condition and life cycle. Fatigue Damage Spectrum(FDS) has evaluated with the Power Spectrum Density(PSD) and the life time of equipment. Finally, provisional vibration qualification test level is evaluated.

• Molecular & Cellular Toxicology
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• 제1권2호
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• pp.111-115
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• 2005

Ultraviolet (UV) radiation to mammalian skin is known to alter cellular function via generation of Reactive Oxygen Species (ROS), DNA damage and DNA lesions, such as pyrimidine dimmers and photoproducts, which could lead to DNA mutation if they are not repaired. In this study, we have investigated the reduction of DNA damage and of apoptosis with a particular attention to genetic effect of paeoniflorin in Normal Human Epidermal Keratinocytes (NHEK). After UVB irradiation from $10\;to\;500mJ/cm^{2}$ to NHEK, Mean Tail Moments (MTM) were increased with UVB dose increase. The greatest amount of strand breaks was induced at $500mJ/cm^{2}$ of UVB. Even at the lowest dose of UVB ($10mJ/cm^{2}$), change in MTM was detected (P<0.0001). Pretreated cell with 0.1% paeoniflorin maximally reduced the level of DNA damage to about 21.3%, compared to untreated cell. In the lower concentrations less than 0.01% of paeoniflorin, MTM had a small increase but paeoniflorin still had reductive effects of DNA damage. We measured the apoptosis suppression of paeoniflorin with annexin V flous staining kit. As we observed under the fluorescence microscopy to detect apoptosis in the irradiated cell, the fluorescence intensity was clearly increased in the untreated cell, but decreased in treated cells with paeoniflorin. These results suggest that paeoniflorin reduces the alteration of cell membranes and prevents DNA damage. Therefore, the use of paeoniflorin as a free radical scavenger to reduce the harmful effects of UV lights such as chronic skin damage, wrinkling and skin cancer can be useful to prevent the formation of photooxidants that result in radical damage.

• Earthquakes and Structures
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• 제8권3호
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• pp.485-509
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• 2015

This paper presents the experimental results obtained by applying frequency-domain structural health monitoring techniques to assess the damage suffered on a special type of damper called Web Plastifying Damper (WPD). The WPD is a hysteretic type energy dissipator recently developed for the passive control of structures subjected to earthquakes. It consists of several I-section steel segments connected in parallel. The energy is dissipated through plastic deformations of the web of the I-sections, which constitute the dissipative parts of the damper. WPDs were subjected to successive histories of dynamically-imposed cyclic deformations of increasing magnitude with the shaking table of the University of Granada. To assess the damage to the web of the I-section steel segments after each history of loading, a new damage index called Area Index of Damage (AID) was obtained from simple vibration tests. The vibration signals were acquired by means of piezoelectric sensors attached on the I-sections, and non-parametric statistical methods were applied to calculate AID in terms of changes in frequency response functions. The damage index AID was correlated with another energy-based damage index -ID- which past research has proven to accurately characterize the level of mechanical damage. The ID is rooted in the decomposition of the load-displacement curve experienced by the damper into the so-called skeleton and Bauschinger parts. ID predicts the level of damage and the proximity to failure of the damper accurately, but it requires costly instrumentation. The experiments reported in this paper demonstrate a good correlation between AID and ID in a realistic seismic loading scenario consisting of dynamically applied arbitrary cyclic loads. Based on this correlation, it is possible to estimate ID indirectly from the AID, which calls for much simpler and less expensive instrumentation.

• 산업경영시스템학회지
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• 제24권68호
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• pp.51-65
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• 2001

This study is to make LCIA(Life Cycle Impact Assessment) easier as a methodology of environmental scores(called E-score) that integrated environmental load of each emission substance based on environmental damage such as in human health, ecosystem and resources category. The concept is to analyzes the LCI(Life Cycle Inventory) and defines the level of environment damages for human health, ecosystem and resources to objective impact assessment standard, and makes the base of marginal damage to calculate the damage factor, which can present the indication that can establish the standard value of environmental impact. First, damages to human health are calculated by fate analysis, effect analysis and damage analysis to get the damage factor of health effect as a DALY(Disability Adjusted Life Years) unit. Second, damages to ecosystem are calculated by fate analysis, effect analysis and damage analysis to get the damage factor of the effect as a PDF(Potentially Disappeared Fraction) unit through linking potentially increased disappeared fraction. Third, damages to resources are carried out by resource analysis and damage analysis for linking the lower fate to surplus energy conception to get damage factor as a MJ(Mega Joule) unit. For the ranking of relative environment load level each other, LCIA can be carried out effectively by applying this E-score methodology to the particular emission substances. A case study has been introduced for the emission substances coming out of a tire manufacturer in Korea. It is to show how to work the methodology. Based on such study result, product-designers or producers now can apply the E-scores presented in this study to the substances of emission list, and then calculate the environment load of the product or process in advance at any time and can see the environment performance comparatively and expected to contribute to the environmental improvement in view of environmental pollution prevention.

• Earthquakes and Structures
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• 제22권2호
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• pp.185-201
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• 2022

Structural Health Monitoring (SHM) is used to provide reliable information about the structure's integrity in near realtime following extreme incidents such as earthquakes, considering the inevitable aging and degradation that occurs in operating environments. This paper experimentally investigates an integrated wireless sensor network (Wi-SN) based monitoring technique for damage detection in concrete structures. An effective SHM technique can be used to detect potential structural damage based on post-earthquake data. Two novel methods are proposed for damage detection in reinforced concrete (RC) building structures including: (i) Jerk Energy Method (JEM), which is based on time-domain analysis, and (ii) Modal Contributing Parameter (MCP), which is based on frequency-domain analysis. Wireless accelerometer sensors are installed at each story level to monitor the dynamic responses from the building structure. Prior knowledge of the initial state (immediately after construction) of the structure is not required in these methods. Proposed methods only use responses recorded during ambient vibration state (i.e., operational state) to estimate the damage index. Herein, the experimental studies serve as an illustration of the procedures. In particular, (i) a 3-story shear-type steel frame model is analyzed for several damage scenarios and (ii) 2-story RC scaled down (at 1/6th) building models, simulated and verified under experimental tests on a shaking table. As a result, in addition to the usual benefits like system adaptability, and cost-effectiveness, the proposed sensing system does not require a cluster of sensors. The spatial information in the real-time recorded data is used in global damage identification stage of SHM. Whereas in next stage of SHM, the damage is detected at the story level. Experimental results also show the efficiency and superior performance of the proposed measuring techniques.

• Journal of Mechanical Science and Technology
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• 제19권10호
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• pp.1891-1901
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• 2005

Recently the authors tried to find damage position only using measured frequency response functions. According to their work, it seems that the algorithm is very practical since it needs only measured frequency responses while other methods require exact analytic model. But when applying the method to a real structure, it requires lots of experiment. The authors, in this time, propose a method to reduce its experimental load by detecting damage within a substructure. This method searches damages not within an entire structure but within substructures. In addition, damage severity was treated in this paper since it is worthy to know damage severity. Optimization technique is used to estimate damage level using measured responses and damage model. Two test examples, a plate and a jointed structure, are chosen to verify the suggesting method.

• 한국공간구조학회논문집
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• 제18권4호
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• pp.89-96
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• 2018

The paper presents the damage estimation of bridge structures in Daegu city based on the scenario-based earthquakes. Since the fragility curves for domestic bridge strucures are limited, the Hazus methodology is employed to derive the fragility curves and estimate the damage. A total of four earthuquake scenarios near Daegu city are assumed and structure damage is investigated for 81 bridge structures. The seismic fragility function and damage level of each bridge had adopted from the analytical method in HAZUS and then, the damage probability using seismic fragility function for each bridge was evaluated. It was concluded that the seismic damage to bridges was higher when the magnitude of the earthquake was large or nearer to the epicenter.

• 한국구조물진단유지관리공학회 논문집
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• 제22권1호
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• pp.137-146
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• 2018

2016년 경주지진 이후로 국내에서도 본격적으로 건축물의 지진대책 강구가 시급한 시점에서 국내에 널리 보급되어 있는 R/C 건축물의 효율적인 내진성능 평가 및 내진보강을 포함한 내진대책을 위한 기초적인 자료를 얻고자, 2016년 경주지진에서 지진피해를 받은 R/C 저층 학교건축물(M학교)을 대상으로 지진피해도구분판정법을 이용하여 잔존내진성능과 지진피해정도를 평가함과 동시에, 부재수준의 비선형동적해석을 수행하여 지진피해정도와의 상관관계를 검토하였다. 지진피해도구분판정에 의한 손상도-I로 분류된 기둥은 2개, 손상도-II가 1개, 손상도-III으로 분류된 기둥이 3개로 각각 평가되어, 최종적으로 평가한 내진성능잔존율(R)은 88.2%로 피해분류는 소규모 피해로 판정되었으며, 또한 비선형동적해석 결과 1층 X방향의 최대응답을 나타낸 기둥의 휨변위는 0.7 mm, 전단변위는 6 mm로 전단균열은 발생하였지만, 전단파괴는 발생하지 않았다. 경주지진에서 지진피해를 입은 M학교의 지진피해가 1층의 X방향에 집중되어 있다는 사실, 휨균열보다는 전단균열이 발생하였다는 사실을 고려한다면 본 연구에서 수행한 비선형동적해석 결과는 2016년 경주지진에서 지진피해를 받은 M학교의 지진피해상황을 잘 반영하고 있다고 사료되며, 국내 기존 저층 R/C 건축물의 효율적인 내진성능 평가 및 내진보강을 포함한 내진대책을 위한 기초적인 자료로서 활용가능하다고 사료된다.

• 대한핵의학회지
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• 제5권2호
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• pp.19-40
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• 1971

Since the iron balance is maintained by regulated intestinal absorption rather than regulated excretion, there have been many reports concerning the factors which may influence the intestinal iron absorption. As the liver is the largest iron storage organ of the body, any hepatocellular damage may result in disturbances in iron metabolism, e,g., frequent co-existence of hemochromatosis and liver cirrhosis, or elevated serum iron level and increased iron absorption rate in patients with infectious hepatitis or cirrhosis. In one effort to demonstrate the influence of hepatocellular damage on intestinal iron absortion, the iron absorption rate was measured in the rabbits whose livers were injured by a single subcutaneous injection of carbon tetrachloride (doses ranging from 0.15 to 0.5cc per kg of body weight) or by a single irradiation of 2,000 to 16,000 rads with $^{60}Co$ on the liver locally. A single oral dose of $1{\mu}Ci\;of\;^{59}Fe$-citrate with 0.5mg of ferrous citrate was fed in the fasting state, 24 hours after hepatic damage had been induced, without any reducing or chelating agents, and stool was collected for one week thereafter. Serum iron levels, together with conventional liver function tests, were measured at 24, 48, 72, 120 and 168 hours after liver damage had been induced. All animals were sacrificed upon the completing of the one week's test period and tissue specimens were prepared for H-E and Gomori's iron stain. Following are the results. 1. Normal iron absorption rate of the rabbit was $41.72{\pm}3.61%$ when 0.5mg of iron was given in the fasting state, as measured by subtracting the amount recovered in stool collected for 7 days from the amount given. The test period of 7 days is adequate, for only 1% of the iron given was excreted thereafter. 2. The intestinal iron absorption rate and serum iron level were significantly increased when the animal was poisoned by a single subcutaneous injection of 0.15cc. per kg. of body weight of carbon tetrachloride or more, or the liver was irradiated with a single dose of 12,000 rads or more. The results of liver function tests which were done simultaneously remained within normal limit except SGOT and SGPT which were somewhat increased. 3. In each case, there has been good correlation between the extent of liver cell damage and degree of increased iron absorption rate or serum iron level. 4. The method of liver damage appeared to make no obvious difference in the pattern of iron deposit in liver. This may be partly due to the fact that tissue specimens were obtained too late, for by this time the elevated serum iron level had returned within normal range and the pathological changes were almost healed. 5. The possible factors and relationship between intestinal iron absorption and hepatic parenchymal cell damage has been discussed.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2009년도 춘계학술대회 논문집
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• pp.15-19
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• 2009

Due to the Japan's Kobe earthquake in 1995, a cut-and-cover tunnel, which is one of subway facilities, collapsed unexpectedly. As a result, also in Korea, seismic performance needs to be secured for the cut-and-cover tunnel and currently, the subway seismic design standard is based on the seismic performance. However, there is no standard for the damage level or stability level of a member for securing the seismic performance, and the definition of multi-level seismic performance is not sufficient. By contrast to this situation, in the Japan's evaluation method of seismic performance, design earthquake ground motion having reflected there into the subway driving stability is clearly defined and the seismic performance required for structures is classified in detail. This study analyzes the Japan's systematic evaluation method of seismic performance for cut-and-cover tunnels of subway.