• 제목/요약/키워드: damage condition

검색결과 2,020건 처리시간 0.032초

성풍탕이 미세아교세포의 NO 생성에 미치는 영향 (Effects of Seongpung-tang on the NO Production of Primary Microglial Cell)

  • 성강경;임창용;이상관
    • 대한한의학회지
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    • 제21권1호
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    • pp.91-98
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    • 2000
  • The water extract of Seongpungtang(SPT) has commonly been used for treatment of ischemic brain damage in Oriental traditional medicine. However, little is known about the mechanism by which the water extract of SPT rescues brain cells from ischemic damage. To elucidate the protective mechanism of ischemic induced cytotoxicity, the regulation of Lipopolysaccharide (LPS) and PMA (phobol-12-myristate-13-acetate) induced iNOS expression in microglial cells was investigated. LPS and PMA treatment for 48 hr in microglial cells markedly induced nitric oxide (NO), but treatment of the cells with the water extract of SPT decreased nitrite formation. In addition, LPS and PMA treatment for 48 hr induced severe cell death in microglial cells. However treatment of the cells with the water extract of SPT did not induce significant changes compared to the control cells. Furthermore, NO production was markedly decreased by treatment of nuclear factor kappa B(NF-kB) inhibitor, pyrrolidine dithiocarbamate(PDTC). According to the above results, it is suggested that the protective effects of the water extract of SPT against ischemic brain damage may be mediated by regulation of iNOS during ischemic condition.

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Long-Term Performance of Geosynthetic Reinforcement Materials with Field Installation Condition

  • Jeon, Han-Yong;Mok, Mun-Sung;Cho, Seong-Ho;Byun, Sung-Weon;Lee, Joon-Seok
    • 한국섬유공학회:학술대회논문집
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    • 한국섬유공학회 2003년도 가을 학술발표회 논문집
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    • pp.305-306
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    • 2003
  • In the case of the geosynthetics usage to soil structure, there are some damages by compaction. And these damages by the installation compaction result in the unexpected changes of short and long term properties of the structure. So in the case of index test, there are some problems to the exact evaluation on the installation damage. Therefore, to the more definite evaluation on the installation damage of geosynthetics, the real site installation damage test is encouraged. (omitted)

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Numerical Ductile Tearing Simulation of Circumferential Cracked Pipe Tests under Dynamic Loading Conditions

  • Nam, Hyun-Suk;Kim, Ji-Soo;Ryu, Ho-Wan;Kim, Yun-Jae;Kim, Jin-Weon
    • Nuclear Engineering and Technology
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    • 제48권5호
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    • pp.1252-1263
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    • 2016
  • This paper presents a numerical method to simulate ductile tearing in cracked components under high strain rates using finite element damage analysis. The strain rate dependence on tensile properties and multiaxial fracture strain is characterized by the model developed by Johnson and Cook. The damage model is then defined based on the ductility exhaustion concept using the strain rate dependent multiaxial fracture strain concept. The proposed model is applied to simulate previously published three cracked pipe bending test results under two different test speed conditions. Simulated results show overall good agreement with experimental results.

명주달팽이의 생활사, 인삼의 피해 및 약제 방제 (Life History, Ginseng Damage and Chemical Control of the Snail Acusta despecta sieboldiana)

  • 김기황
    • Journal of Ginseng Research
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    • 제16권2호
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    • pp.146-150
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    • 1992
  • Life history, ginseng damage, and chemical control of the snail Acusta despecta sieboldiana Pfeiffer were investigated in the field and laboratory conditions from 1987 to 1990. Eggs of the snail were whitish globular and 1.,93${\pm}$ 0.09 mm in diameter which were deposited as egg mass composed of 28.4${\pm}$ 15.4 eggs. Egg period was 11.8${\pm}$ 1.6 days under the laboratory condition. Most eggs were laid during mid July in the field. The snail had a life cycle of a year and hibernated from November to April. Significant ginseng damages by the snail (over 10% to the total number of plants) were observed only in the three to five year old ginseng fields with rice straw mulching. Based on the dates that the first ginseng damages were observed and on the questionary examination, ginseng damages seemed to occur from May to July. Metaldehyde (6%) bait showed reliable control effects on the snail.

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Characterization of Surface Damage and Contamination of Si Using Cylindrial Magnetron Reactive Ion Etching

  • Young, Yeom-Geun
    • 한국재료학회지
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    • 제3권5호
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    • pp.482-496
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    • 1993
  • Radiation damage and contamination of silicons etched in the $CF_4+H_2$ and $CHF_3$ magnetron discharges have been characterized using Schottky diode characteristics, TEM, AES, and SIMS as a function of applied magnetic field strength. It turned out that, as the magnetic field strength increased, the radiation damage measured by cross sectional TEM and by leakage current of Schottky diodes decreased colse to that of wet dtched samples especially for $CF_4$ plasma etched samples, For $CF_4+H_2$and $CHF_3$ etched samples, hydrogen from the plasmas introduced extended defects to the silicon and this caused increased leakage current to the samples etched at low magnetic field strength conditions by hydrogen passivation. The thickness of polymer with the increasing magnetic field strength and showed the minimum polymer residue thickness near the 100Gauss where the silicon etch rate was maximum. Also, other contaminants such as target material were found to be minimum on the etched silicon surface near the highest etch rate condition.

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노인들의 건강식품 피해예방을 위한 사용실태 조사 (Investigation for health food intake to prevent damage of the elderly)

  • 김효정;김미라
    • 한국생활과학회지
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    • 제15권5호
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    • pp.849-858
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    • 2006
  • This research aimed to survey problems related to the elderly's purchasing trends and habitual use of health food; it was in order to effectively prevent the monetary and health damage to the elderly of health foods. In February 2006, the data were collected from 271 of the elderly people living in Goyang-si, Kyunggi-Do. The results of the study indicated: first, more than 50% of the respondents had much interest in health foods, and 42.8% of them answered they were taking health foods. Second, about 62% of 116 respondents who were taking health foods were taking one kind of them, for the purpose of maintaining and improving their health condition. Third, the major information regarding health foods was acquired from their family members, relatives and friends, or TV, radio and journals. Lastly, 75% of respondents even did not know whether there was a relief system for damage related to health foods.

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Hepatoprotective activity of Indigofera aspalathoides extract against CCl4-induced liver damage

  • Gupta, M.;Mazumder, U.K.;Haldar, P.K.;Manikandan, L.;Senthilkumar, G.P.;Kander, C.C.
    • Advances in Traditional Medicine
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    • 제4권2호
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    • pp.100-103
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    • 2004
  • The plant Indigofera aspalathoides are used by a large number of tribes in India for the treatment of various hepatic disorder. The methanol extract of Indigofera aspalathoides (MEIA) was evaluated for its effect on carbontetrachloride $(CCl_{4})$ induced liver damage. Biochemical parameters such as serum glutamine oxaloacetate trasaminase (SGOT), serum glutamine pyruvate transaminase (SGPT), serum alkaline phosphatase (ALP), total serum protein (TP), thiobarbituric acid reactive substances (TBRS) and glutathione content of the liver were estimated to assess liver function and metabolism. Biochemical observations suggest that methanol extract of Indigofera aspalathoides (MEIA) significantly restored the liver function and metabolism towards normal condition in $CCl_{4}$-induced hepatic damage.

Investigation of the Contributions of Creep and Thermal Fatigue to Failure of a High-Intermediate Pressure Steam Turbine Casing

  • Lee, Jaehong;Jung, Nam-gun
    • KEPCO Journal on Electric Power and Energy
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    • 제6권1호
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    • pp.41-47
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    • 2020
  • The contribution of damage mechanisms to failure of steam turbine casing made of Cr-Mo-V steel was investigated. Creep-fatigue interaction on the HP side corner of turbine casing was revealed as the root cause of the catastrophic failure performed by metallurgical analysis. The steady-state pressure and transient thermal stress were analyzed based on the actual operating condition of the thermal plant. Damage of creep-fatigue interaction to crack initiation was evaluated with multiaxial effects. The contribution ratio of creep and fatigue to the crack initiation was estimated to 3:1. Temporary geometrical correct action with repair weld was executed. For long-term operation, design improvement of casing equipment for creep resistance should be needed.

압전소자를 이용한 TRUSS 구조물의 볼트 결합 토크 추정에 관한 연구 (Study of Bolt Coupling Torque Conclusion of TRUSS Structure Using PZT Patches)

  • 한수현;김병진;홍동표
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2005년도 추계학술대회논문집
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    • pp.612-615
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    • 2005
  • This studies presented truss frame which use aluminum beam by damage model. Truss frame which each joint part is contracted by bolt contracted conclusion of each bolt by 3.0 N/m. And measured impedance change that appear making bolt 0.5 N/m on damage condition 8 times. Compares impedance change of 5 segments that was set by measurement area and displayed result. To measure torque change of bolt, other damage model did not apply.

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SiC/p-Aramid 복합방적사 제조기술 연구 (Research of the Composite Spun Yarn Manufacturing Process using Silicon Carbide and Para Aramid Fiber)

  • 김북성;유희준
    • 한국염색가공학회지
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    • 제33권4호
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    • pp.309-316
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    • 2021
  • Due to the rigid nature of the silicon carbide fiber(SiC), fiber damage occurs from the friction during the carding process. This damage not only lowers the spun yarn yield, but also lowers the heat resistance of the spun yarn, so that ultra-high heat resistant yarn cannot be manufactured. Therefore, in the carding process where the most friction between fiber and machine(wire, etc.) occurs, some factors were modified and tested, and as a result of measuring the change in physical properties, fiber damage decreased due to the wire angle or wire density, resulting in improved yield. The test method used to measure the yield of SiC fiber was the carbonization method, and the content of SiC fibers was calculated using the remaining amount after carbonization. Carbonization test was performed at air condition, 700℃, and for 2 hours. Analysis by SEM-EDX showed that the carbide was consistent with the composition of the SiC fiber.