• Title/Summary/Keyword: damage/damage identification

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Effectiveness of Intraoperative Neuromonitoring According to the Mechanism of Recurrent Laryngeal Nerve Injury During Thyroid Surgery (갑상선 수술 중 반회후두신경의 손상 기전에 따른 신경 감시술의 효용성)

  • Shin, Sung-Chan;Lee, Byung-Joo
    • Korean Journal of Head & Neck Oncology
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    • v.36 no.1
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    • pp.9-14
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    • 2020
  • Visual identification of recurrent laryngeal nerve (RLN) is considered as a gold standard of RLN preservation during thyroid surgery. Intraoperative neuromonitoring (IONM) is classified into the intermittent type and continuous type and helps surgeons identify the functional integrity of RLN and predict the postoperative vocal cord function. RLN injury during thyroid surgery is associated with tumor factors and surgeon factors. Tumor factors mean such as direct tumor invasion, adhesion of RLN to the tumor, and compression by a large thyroid tumor. Surgeon factors include nerve transection, stretching, thermal injury, and ligation injury. A recent meta-analysis reported that the IONM could reduce the RLN injury. Considering various nerve injury mechanism, we suggest that using both I-ONM and C-IONM together is more effective method in preventing nerve damage than using I-IONM alone.

SURFACE DEFORMATION MONITORING USING TERRASAR-X INTERFEROMETRY

  • Kim, Sang-Wan;Wdowinski, Shimon;Dixon, Tim
    • Proceedings of the KSRS Conference
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    • 2008.10a
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    • pp.422-425
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    • 2008
  • TerraSAR-X is new radar satellite operated at X-band, multi polarization, and multi beam mode. Compared with C-band or L-band SAR, the X-band system inherently suffers from more temporal decorrelation, but is more sensitive to surface deformation monitoring due to short wavelength (3.1 cm) and high spatial resolution (1m-3m). It is generally expected that sensitivity to estimate surface movement using TerraSAR-X will be increased by the factor of 10, compared to current C-band system with low spatial resolution such as ERS-2, Envisat. Many urban areas are experiencing land subsidence due to water, oil and natural gas withdrawal, underground excavation, sediment compaction, and so on. Monitoring of surface deformation is valuable for effectively limiting damage areas. In addition high accuracy and spatially dense subsidence map can be achieved by X-band InSAR observation, promoting identification and separation of various subsidence processes and leading to enhanced understanding via mechanical modeling. In this study we will introduce some initial InSAR results using new TerraSAR-X SAR data for surface deformation monitoring.

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Application of Event Tree Technique for Quantification of Nuclear Power Plant Safety (원자력발전소의 정량적인 안전 해석을 위한 사건수목 기법의 응용)

  • Kim, See-Darl;Jin, Young-Ho;Kim, Dong-Ha;Park, Soo-Yong;Park, Jong-Hwa
    • Journal of the Korean Society of Safety
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    • v.15 no.2
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    • pp.126-135
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    • 2000
  • Probabilistic Safety Assessment (PSA) is an engineering analysis method to identify possible contributors to the risk from a nuclear power plant and now it has become a standard tool in safety evaluation of nuclear power plants. PSA consists of three phases named as Level 1, 2 and 3. Level 2 PSA, mainly focused in this paper, uses a step-wise approach. At first, plant damage states (PDSs) are defined from the Level 1 PSA results and they are quantified. Containment event tree (CET) is then constructed considering the physico-chemical phenomena in the containment. The quantification of CET can be assisted by a decomposition event tree (DET). Finally, source terms are quantitatively characterized by the containment failure mode. As the main benefit of PSA is to provide insights into plant design, performance and environmental impacts, including the identification of the dominant risk contributors and the comparison of options for reducing risk, this technique is expected to be applied to the industrial safety area.

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Ambient and forced vibration testing with numerical identification for RC buildings

  • Aras, Fuat
    • Earthquakes and Structures
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    • v.11 no.5
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    • pp.809-822
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    • 2016
  • Reinforced concrete buildings constitute the majority of the building stock of Turkey and much of them, do not comply the earthquake codes. Recently there is a great tendency for strengthening to heal their earthquake performance. The performance evaluations are usually executed by the numerical investigations performed in computer packages. However, the numerical models are often far from representing the real behaviour of the existing buildings. In this condition, experimental modal analysis fills a gap to correct the numerical models to be used in further analysis. On the other hand, there have been a few dynamic tests performed on the existing reinforced concrete buildings. Especially forced vibration survey is not preferred due to the inherent difficulties, high cost and probable risk of damage. This study applies both ambient and forced vibration surveys to investigate the dynamic properties of a six-story residential building in Istanbul. Mode shapes, modal frequencies and damping ration were determined. Later on numerical analysis with finite element method was performed. Based on the first three modes of the building, a model updating strategy was employed. The study enabled to compare the results of ambient and forced vibration surveys and check the accuracy of the numerical models used for the performance evaluation of the reinforced concrete buildings.

Determination of Degraded Properties of Vibrating Laminated Composite Plates for Different Layup Sequences (적층배열 변화에 따른 진동하는 복합재료 적층 구조의 미시역학적 물성변화 추정)

  • Kim, Gyu-Dong;Lee, Sang-Youl
    • Composites Research
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    • v.28 no.5
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    • pp.277-284
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    • 2015
  • This paper presents a method to detect the fiber property variation of laminated GFRP plates from natural frequency response data. The combined finite element analysis using ABAQUS and the inverse algorithm described in this paper may allow us not only to detect the deteriorated elements from the mirco-mechanical point of view but also to find their numbers, locations, and the extent of damage. To solve the inverse problem using the combined method, this study uses several natural frequencies instead of mode shapes in a structure as the measured data. Several numerical results show that the proposed system is computationally efficient in identifying fiber stiffness degradation for complex structures such as composites with various layup sequences.

Vibration analysis of mountain tunnel lining built with forepoling method

  • Gao, Yang;Jiang, Yujing;Du, Yanliang;Zhang, Qian;Xu, Fei
    • Smart Structures and Systems
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    • v.21 no.5
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    • pp.583-590
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    • 2018
  • Nowadays, many tunnels have been commissioned for several decades, which require effective inspection methods to assess their health conditions. The ambient vibration test has been widely adopted for the damage identification of concrete structures. In this study, the vibration characters of tunnel lining shells built with forepoling method was analyzed based on the analytical solutions of the Donnell-Mushtari shell theory. The broken rock, foreploing, rock-concrete contacts between rock mass and concrete lining, was represented by elastic boundaries with normal and shear stiffness. The stiffness of weak contacts has significant effects on the natural frequency of tunnel lining. Numerical simulations were also carried out to compare with the results of the analytical methods, showing that even though the low nature frequency is difficult to distinguish, the presented approach is convenient, effective and accurate to estimate the natural frequency of tunnel linings. Influences of the void, the lining thickness and the concrete type on natural frequencies were evaluated.

Identification of differentially expressed Genes by methyl mercury in neuroblastoma cell line using SSH

  • Kim, Youn-Jung;Chang, Suk-Tai;Ryu, Jae-Chun
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2002.10a
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    • pp.167-167
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    • 2002
  • Methylmercury (MeHg), one of the heavy metal compound, can cause severe damage to the central nervous system in humans. Many reports have contributed MeHg poisoning to contaminated foods and release into the environment. Despite many studies on the pathogenesis of MeHg-induced central neuropathy, no useful mechanism of toxicity has been established. To find genes differentially expressed by MeHg in neuronal cell, we peformed forward and reverse suppression subtractive hybridization (SSH) method on mRNA derived from neuroblastoma cell line, SH-SY5Y treated with solvent (DMSO) and 6.25 uM (IC$\sub$50/) MeHg. Differentially expressed CDNA clones were sequenced and the mRNAs were re-examined on Northern blots. These sequences were identified by BLAST homology search to known genes or expressed sequence tags (ESTs). Analysis of these sequences has provided an insight into the biological effects of MeHg in the pathogenesis of neurodegenerative disease and a possibility to develop more efficient and exact monitoring system of heavy metals as common environmental pollutants.

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Radiological Evaluation of CT Contrast Medium Extravasation (CT 조영제 혈관외유출의 방사선학적 고찰)

  • Kweon, Dae-Cheol;Park, Chang-Hee;Jeong, Jae-Ho;Kang, Hui-Doo;Song, Woon-Heung
    • Korean Journal of Digital Imaging in Medicine
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    • v.10 no.2
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    • pp.39-49
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    • 2008
  • Extravasation of contrast material is a not infrequent complication of enhanced imaging studies and large volume extravasation may result in severe damage. Subcutaneous extravasation of the radiographic contrast medium is one of the complications of the contrast medium-enhanced procedures. Automated power injectors enable the contrast material to be delivered at a uniform high-flow-rate and as a nonfragmented bolus, and this is essential for many contrast material enhanced CT(computed tomography) applications. The major risk associated with the use of automated power injectors is the well known complication of contrast material extravasation at the injection site. Automated injection of CT contrast material can produce the compartment syndrome. Selection of the nonionic contrast material after careful evaluation of the intravenous administration site and monitoring of the patient during the use of a mechanical power injector may help minimize or prevent extravasation injuries. Early identification is important and conservative management is effective in most cases. Prevention of these injuries with the education of radiological technologist remains the ultimate aim.

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Species-Specific Duplex PCR for Detecting the Important Fish Pathogens Vibrio anguillarum and Edwardsiella tarda

  • Jo, Geon-A;Kwon, Sae-Bom;Kim, Na-Kyeong;Hossain, Muhammad Tofazzal;Kim, Yu-Ri;Kim, Eun-Young;Kong, In-Soo
    • Fisheries and Aquatic Sciences
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    • v.16 no.4
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    • pp.273-277
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    • 2013
  • Vibriosis caused by Vibrio anguillarum and edwardsiellosis caused by Edwardsiella tarda are septicemic diseases of many commercially important freshwater and marine fishes, and threaten the aquaculture industry in Korea. Early diagnosis and accurate identification of these two bacterial species could help to prevent these diseases and minimize the damage to cultured marine species. This study designed a duplex polymerase chain reaction (PCR) method for the simultaneous detection of two major fish pathogens: V. anguillarum and E. tarda. Each pair of oligonucleotide primers exclusively amplified the target groEL gene of the specific microorganism. Twenty-two Vibrio and ten non-Vibrio enteric species were used to check the specificity of the primers, which were found to be highly specific for the target species, even among closely related species. The detection limit was 400 pg for V. anguillarum and 4 ng for E. tarda when mixed purified DNA was used as the template. This assay showed high specificity and sensitivity in the simultaneous detection of V. anguillarum and E. tarda from artificially inoculated seawater and fish.

The MAK16 Gene of Entamoeba histolytica and Its Identification in Isolates from Patients

  • Crisostomo-Vazquez, Maria del Pilar;Marevelez-Acosta, V?ctor Alberto;Flores-Luna, Andres;Jimenez-Cardoso, Enedina
    • Parasites, Hosts and Diseases
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    • v.52 no.4
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    • pp.429-433
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    • 2014
  • To identify sequences of Entamoeba histolytica associated with the development of amebic liver abscess (ALA) in hamsters, subtractive hybridization of cDNA from E. histolytica HM-1:IMSS under 2 growth conditions was performed: 1) cultured in axenic medium and 2) isolated from experimental ALA in hamsters. For this procedure, 6 sequences were obtained. Of these sequences, the mak16 gene was selected for amplification in 29 cultures of E. histolytica isolated from the feces of 10 patients with intestinal symptoms and 19 asymptomatic patients. Only 5 of the 10 isolates obtained from symptomatic patients developed ALA and amplified the mak16 gene, whereas the 19 isolates from asymptomatic patients did not amplify the mak16 gene nor did they develop ALA. Based on the results of Fisher's exact test (P<0.001), an association was inferred between the presence of the mak16 gene of E. histolytica and the ability to develop ALA in hamsters and with the patient's symptoms (P=0.02). The amplification of the mak16 gene suggests that it is an important gene in E. histolytica because it was present in the isolates from hamsters that developed liver damage.