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Ameliorating Effect of Water Extract from Dendropanax morbifera Lev. on Memory Dysfunction in Streptozotocin-induced Diabetic Rats (스트렙토조토신(Streptozotocin) 유발 당뇨 동물모델에서 황칠나무 잎 추출물의 학습 및 기억력 개선 효과)

  • Kim, Ji Hye;Bae, Dong hyuck;Lee, Uk;Heo, Ho Jin
    • Korean Journal of Food Science and Technology
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    • v.48 no.3
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    • pp.275-283
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    • 2016
  • An anti-amnesic effect of water extract from Dendropanax morbifera Lev. leaves (DMW) on memory dysfunction in streptozotocin-induced diabetic rats was investigated to assess its potential industrial value. Daily administration of DMW (11 weeks) significantly reduced serum glucose, insulin, and blood urea nitrogen (BUN) levels increased by an intraperitoneal injection of streptozotocin (STZ, 55 mg/kg). In addition, the administration of DMW decreased escape latency and increased the time spent in the platform quadrant in the Morris water maze test. Step-through latency in a passive avoidance test was also improved. Finally, DMW produced ameliorating effects on STZ-induced cholinergic deficit through an inhibitory effect on acetylcholinesterase and the increment of acetylcholine level in the hippocampus. These results suggest that DMW might be used as a natural substance for improving diabetic induced cognitive impairment.

A Study on Epidemiology of Drowning Accidents associated with Recreational Aquatic Activity (여가 수중활동과 관련된 익사사고의 역학 분석 연구)

  • Son, Jae-Young;Ko, Wi-Sug;Cho, Byung-Jun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.11
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    • pp.5060-5065
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    • 2012
  • The purpose of this study was to report the incidence of drowning accident in order to prevent and decrease the accidents of drowning. Data were obtained on all accidents of drowning accidents occurred from January to December 2007 were identified by using the Emergency Activity Daily Report Data from the National Emergency Management Agency (NEMA). The age, weather, date, location, time and case of the drowning accident were examined. The Chi-square test was used to compare each group. All comparisons were made at the p<0.05 level of significance. The result show that the age of drowning accidents for victims aged 20-29 was 27.9%, and for victims aged 30-39 years, 18.7%. In reguard to the age group, drowning accidents during recreational aquatic activity was age 20-39; 51(44.8%). In reguard to the locations, the number of drowning accidents in a lake or reservoir during recreational aquatic activity was 62(53.4%). The number of drowning accidents in a lake or reservoir during etc was 51(58%). In reguard to the days, the number of drowning accidents on Saturday during recreational aquatic activity was 30(25.8%), on Sunday 32(27.6%). The weather of drowning accidents during recreational aquatic activity was sunny 60(51.8%), rainy 40(34.4%), cloudy 16(13.8%). The season of drowning accidents during recreational aquatic activity was summer 53(45.7%). In reguard to season, two groups are significantly different. Drowning is a leading cause of injury related accidents. Understanding the characteristics of drowning is the first step to developing prevention strategies that may be beneficial for people of all ages and under nearly all circumstances are increased swimming ability, lifeguard staffing, providing life jackets, and public education activities.

The effect of protease on growth performance, nutrient digestibility, and expression of growth-related genes and amino acid transporters in broilers

  • Park, Jae Hong;Lee, Sang In;Kim, In Ho
    • Journal of Animal Science and Technology
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    • v.62 no.5
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    • pp.614-627
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    • 2020
  • During the course of this trial, our team assessed the influence of protease upon the growth performance, the nutrient digestibility, and the expression of growth-related genes and amino acid transporters within the liver, muscle, and small intestines of broilers. During the first step, our team allocated 600 broilers into four dietary treatments for a period of 35 days in order to measure the growth performance and nutrient digestibility of the broilers selected. The separate treatments contained 10 replicates (15 birds per replicate). The treatments were composed of: 1) CON, basal diet; 2) T1, basal diet + 0.03% protease; 3) T2, basal diet + 0.06% protease; and 4) T3, basal diet + 0.09% protease. Next, the broiler chick sample tissue was harvested from the CON and T3 groups in order to conduct gene expression analysis following the feeding trials the broilers underwent. Our team discovered that the broilers fed protease diets possessed increased body weight and an average daily gain, but conversely, had lower feed conversion ratios when their dietary protease levels increased from 0% to 0.09% (p < 0.05). Additionally, significant linear improvements were identified among the nutrient digestibility of dry matter, crude protein, energy, and amino acids within broilers supplied with protease diets when contrasted and compared with broilers supplied with the basal diet (p < 0.05). In addition, the gene expression of the genes IGF1, IGF2, GH, and LEP in the liver, and the genes MYOD1 and MYOG in the breast muscles, was significantly increased after broilers were fed with a protease diet as compared to broilers that subsisted on a basal diet (p < 0.05). Protease supplementation also raised the expression levels within these amino acid transporters: SCL6A19, SLC7A1, SLC7A7, SLC7A2, SLC7A6, SLC7A9, and SLC15A1, located in the small intestine, when compared to the basal diet (p < 0.05). Our results suggest that protease supplementation in their diet improved the growth performance of broilers via an increase in the expression growth-related genes within broiler liver and muscle tissue. In addition, protease supplementation enhanced broiler digestibility via the upregulation of amino acid transporter expression within the small intestine.

Development of a Meso-Scale Distributed Continuous Hydrologic Model and Application for Climate Change Impact Assessment to Han River Basin (분포형 광역 수문모델 개발 및 한강유역 미래 기후변화 수문영향평가)

  • Kim, Seong-Joon;Park, Geun-Ae;Lee, Yong-Gwan;Ahn, So-Ra
    • Journal of the Korean Association of Geographic Information Studies
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    • v.17 no.3
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    • pp.160-174
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    • 2014
  • The purpose of this paper is to develop a meso-scale grid-based continuous hydrological model and apply to assess the future watershed hydrology by climate change. The model divides the watershed into rectangular cells, and the cell profile is divided into three layered flow components: a surface layer, a subsurface unsaturated layer, and a saturated layer. Soil water balance is calculated for each grid cell of the watershed, and updated daily time step. Evapotranspiration(ET) is calculated by Penman-Monteith method and the surface and subsurface flow adopts lag coefficients for multiple days contribution and recession curve slope for stream discharge. The model was calibrated and verified using 9 years(2001-2009) dam inflow data of two watersheds(Chungju Dam and Soyanggang Dam) with 1km spatial resolution. The average Nash-Sutcliffe model efficiency was 0.57 and 0.71, and the average determination coefficient was 0.65 and 0.72 respectively. For the whole Han river basin, the model was applied to assess the future climate change impact on the river bsain. Five IPCC SRES A1B scenarios of CSIRO MK3, GFDL CM2_1, CONS ECHO-G, MRI CGCM2_3_2, UKMO HADGEMI) showed the results of 7.0%~27.1 increase of runoff and the increase of evapotranspiration with both integrated and distributed model outputs.

An Exploratory Investigation of the Imaginative Writing Processes of Middle School Students (중학생의 상상하는 글쓰기 과정에 대한 탐색적 연구)

  • Yang, Chanho;Lee, Jaewon;Noh, Taehee
    • Journal of The Korean Association For Science Education
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    • v.34 no.5
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    • pp.511-521
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    • 2014
  • In this study, we conducted an exploratory investigation of the imaginative writing processes of middle school students. Twelve 8th graders were asked to imagine and write about the daily life of atoms, assuming that they became specific atoms for themselves. The think-aloud method was used to investigate students' writing processes. We recorded students' writing processes, and also collected the data through interviews to clarify ambiguities in their writing processes. The analyses of the results revealed that their imaginative writing processes could be classified into the three types by the two aspects of writing process components (retrieving information and generating ideas). That is, the integration of retrieving information and generating ideas, the predominant retrieving information, and the predominant generating ideas. The students who were classified into the type of the integration of retrieving information and generating ideas came up with a story and properly introduced science concepts into it. These suggested that this type of students expressed their own understanding more effectively, and that this type was most appropriate for imaginative writing in learning science. The results also showed that the imaginative writing processes were greatly influenced by whether the planning step was adequately considered or not. On the bases of the results, we suggest the teaching strategies for effective imaginative writing in learning science.

Methodology to Apply Low Spatial Resolution Optical Satellite Images for Large-scale Flood Mapping (대규모 홍수 매핑을 위한 저해상도 광학위성영상의 활용 방법)

  • Piao, Yanyan;Lee, Hwa-Seon;Kim, Kyung-Tak;Lee, Kyu-Sung
    • Korean Journal of Remote Sensing
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    • v.34 no.5
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    • pp.787-799
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    • 2018
  • Accurate and effective mapping is critical step to monitor the spatial distribution and change of flood inundated area in large scale flood event. In this study, we try to suggest methods to use low spatial resolution satellite optical imagery for flood mapping, which has high temporal resolution to cover wide geographical area several times per a day. We selected the Sebou watershed flood in Morocco that was occurred in early 2010, in which several hundred $km^2$ area of the Gharb lowland plain was inundated. MODIS daily surface reflectance product was used to detect the flooded area. The study area showed several distinct spectral patterns within the flooded area, which included pure turbid water and turbid water with vegetation. The flooded area was extracted by thresholding on selected band reflectance and water-related spectral indices. Accuracy of these flooding detection methods were assessed by the reference map obtained from Landsat-5 TM image and qualitative interpretation of the flood map derived. Over 90% of accuracies were obtained for three methods except for the NDWI threshold. Two spectral bands of SWIR and red were essential to detect the flooded area and the simple thresholding on these bands was effective to detect the flooded area. NIR band did not play important role to detect the flooded area while it was useful to separate the water-vegetation mixed flooded classes from the purely water surface.

Greedy Heuristic Algorithm for the Optimal Location Allocation of Pickup Points: Application to the Metropolitan Seoul Subway System (Pickup Point 최적입지선정을 위한 Greedy Heuristic Algorithm 개발 및 적용: 서울 대도시권 지하철 시스템을 대상으로)

  • Park, Jong-Soo;Lee, Keum-Sook
    • Journal of the Economic Geographical Society of Korea
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    • v.14 no.2
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    • pp.116-128
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    • 2011
  • Some subway passengers may want to have their fresh vegetables purchased through internet at a service facility within the subway station of the Metropolitan Seoul subway system on the way to home, which raises further questions about which stations are chosen to locate service facilities and how many passengers can use the facilities. This problem is well known as the pickup problem, and it can be solved on a traffic network with traffic flows which should be identified from origin stations to destination stations. Since flows of the subway passengers can be found from the smart card transaction database of the Metropolitan Seoul smart card system, the pickup problem in the Metropolitan Seoul subway system is to select subway stations for the service facilities such that captured passenger flows are maximized. In this paper, we have formulated a model of the pickup problem on the Metropolitan Seoul subway system with subway passenger flows, and have proposed a fast heuristic algorithm to select pickup stations which can capture the most passenger flows in each step from an origin-destination matrix which represents the passenger flows. We have applied the heuristic algorithm to select the pickup stations from a large volume of traffic network, the Metropolitan Seoul subway system, with about 400 subway stations and five millions passenger transactions daily. We have obtained not only the experimental results in fast response time, but also displayed the top 10 pickup stations in a subway guide map. In addition, we have shown that the resulting solution is nearly optimal by a few more supplementary experiments.

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Ontology Modeling and Its Application for Managing Control Points (기준점 관리를 위한 온톨로지 모델링과 적용 방안)

  • Cui, Yulan;Hwang, Hyun-Suk;Shin, Seong-Hyun;Suh, Yong-Cheol;Kim, Chang-Soo
    • Journal of the Korean Association of Geographic Information Studies
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    • v.11 no.3
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    • pp.34-42
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    • 2008
  • The control points are important assets of countries which express the most accurate location information that is used in surveying land and other measurements. The location information has played an important role in our daily lives with the development of ubiquitous technology. While many researchers have recently applied new technology like RFID(Radio-Frequency Identification) to the effective management of control points, the research into data retrieval and the interoperability of control point data is still primitive step. Therefore, we construct a data modeling to effectively manage control points using ontology data structure and focus on semantic retrieval method. Our retrieval system can provide the inferred and associated information among data using Prot$\acute{e}$g$\acute{e}$-OWL tool. Our system has advantages in reducing the number of repeated queries by hierarchy searching and improving the searching time by association searching. Also, we propose an effective method to construct retrieval systems being able to edit items of categories and properties without editing the related codes.

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An Estimation of Mean Background Concentrations of Greenhouse Gases Observed on Ulleungdo (울릉도 온실기체 관측자료를 이용한 배경대기 평균농도 산정)

  • Lim, Yun-Kyu;Moon, Yun-Seob;Kim, Jin-Seog;Song, Sang-Keun;Hong, Ji-Hyung
    • Journal of the Korean earth science society
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    • v.33 no.1
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    • pp.32-38
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    • 2012
  • Mean background concentrations of greenhouse gases such as $CO_2$ and $CH_4$ were estimated on Ulleungdo using PICARRO Cavity Ring-Down Spectroscopy (CRDS) analyzer. To improve the accuracy of $CO_2$ and $CH_4$ concentrations, a standardized QA${\cdot}$QC (Quality Assurance Quality Control) procedure was employed with three steps: 1) the inspection procedure of physical limitation (e.g. the exclusion of data corresponding to the number of data of ${\leq}$50%) for hourly mean values, 2) a stage inspection (e.g. the use of data corresponding to ${\geq}15$ observations per day) for daily mean values, and 3) a fast fourier transform (FFT) analysis using curve-fitting methods for the investigation of climatic characteristics. The monthly mean concentrations of $CO_2$ and $CH_4$ derived from three-step QA${\cdot}$QC procedure were then compared with those observed at Anmyundo (Korea) and Ryori (Japan). Overall, the error of mean $CO_2$ and $CH_4$ concentrations estimated in this study distinctly decreased. However, in comparison with their concentrations monitored at Ryori, the $CO_2$ concentration at estimated at Ulleungdo is soemwhat lower than that of Anmyundo due to the missing data, which is statistically significant. On the other hand, the former has a statistically significant higher value of $CH_4$ that of the latter.

The Next Wave in Display Innovation

  • Webster, Steven C.
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.4-4
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    • 2008
  • The progress in flat panel displays over the last two decades has been astonishing. In just 20 years, the LCD-TV grew up from a 2-inch curiosity, to an industry that will sell about 120 million flat panel TV's this year, with viewing area up to 4000 times larger. That success is based on continuous innovation, especially in manufacturing processes. For the next decade to bring another doubling of the business, progress will need to continue in four major areas: Human factors, ecological impact, visual quality, and of course continued drive towards affordability. This talk will detail the technology advances that can allow this industry to meet those challenges. Human factors. Today, we adapt our lifestyle to our technology. People organize their offices, and their homes, around displays. We pass around mobile phones to share images, rather than experiencing them as a group. Billions of newspapers continue to be sold daily. Advances in flexible displays can lead to large portable displays. "New era projection" includes the handheld Pico Projectors that are already on the market, and will ultimately appear integrated in mobile phones the same way cameras do today. "Eco" impact. Today TV's are one of the top energy consumers in a U.S. home, and the fastest growing. Watching a large flat panel TV can cost twice as much as running a large refrigerator. With today's concern about energy consumption, regulations are starting to emerge worldwide to limit TV electrical use. Fortunately, good solutions exist in using light management films to eliminate bulbs, saving power without increasing cost. Going forward, LED backlights will drive another step downward. OLED displays might be the ultimate solution. Visual quality. The color of an LCD-TV is still often considered inferior to a far less expensive CRT. And almost all displays suffer from representing a three-dimensional world on a two dimensional surface. The technology to improve color is available today, and will likely move from premium sets into the mainstream as costs come down. 3D is now arriving in movie theaters worldwide, and that will drive up the demand for similar realistic images in home theaters. And the technology is emerging today for 3D representation to move beyond specialized applications into everyday use, on screens large and small. Affordability. The world takes cost-down miracles for granted in consumer electronics. Each of these other advances will be balanced with a drive for affordability, especially as the market grows in emerging countries. The other three challenges must be met without increasing cost. Putting this all together, the next few years will emphasize "eco friendly" designs, and enhanced images such as 3D. By 2013 we will start to see serious penetration by emissive technologies (OLED, high efficiency plasma, or other), with the "ultimate display" likely not in the market for a decade. Lots of opportunities for innovation remain ahead of us.

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