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뇌 MR영상 수동분할을 위한 VTK기반의 3차원 가시화 소프트웨어 툴 설계 (Design of 3D Visualization Software Tool Based on VTK for Manual Brain Segmentation of MRI)

  • 윤호성;;문치웅;김영훈;최흥국
    • 한국멀티미디어학회논문지
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    • 제18권2호
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    • pp.120-127
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    • 2015
  • Mild Cognitive Impairment(MCI) is a prior step to Alzheimer's Disease(AD). It is different from AD which is seriously affecting daily life. Particularly, the hippocampus could be charged a crucial function for forming memory. MCI has a high risk about progress to AD. Our investigated research for a relationship between hippocampus and AD has been studied. The measurement of hippocampus volumetric is one of the most commonly used method. The three dimensional reconstructed medical images could be passible to interpret and its examination in various aspects but the cost of brain research with the medical equipment is very high. In this study, 3D visualization was performed from a series of brain Magnetic Resonance Images(MRI) and we have designed and implemented a competitive software tool based on the open libraries of Visualization ToolKit(VTK). Consequently, our visualization software tool could be useful to various medical fields and specially prognosis and diagnosis for MCI patients.

PNF 훈련 프로그램이 건강한 노인의 기능적 평가 측정과 보행에 미치는 효과 (Effect of a PNF Training Program on Functional Assessment Measures and Gait Parameters in Healthy Older Adults)

  • 마상렬;김형동
    • The Journal of Korean Physical Therapy
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    • 제22권1호
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    • pp.39-45
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    • 2010
  • Purpose: The purpose of this study was to examine changes in functional assessment measures (FAMs) and spatiotemporal gait parameters (STGPs) in healthy older adults before and after a 6-week intervention of a proprioceptive neuromuscular facilitation (PNF) training program. Methods: Thirty healthy older adults (mean age: $73.37{\pm}1.21$ age range: 65-79) were randomly assigned either to an experimental group (participating in a 6-week intervention of PNF training) or a control group (only performing daily activities). Participants in the control group did not receive any training program. Performance was assessed by recording changes in the FAMs and STGPs using functional assessment tools and GAITRite. Results: Participants in the PNF group showed significantly improved functional assessment measures and increased stride length, cadence, velocity, and step width (p<0.05). No significant differences in FAMs and STGPs were found in the control group (p>0.05). Conclusion: Participation in a PNF training program improves FAMs and STGPs, thereby increasing the ability of healthy older adults to maintain dynamic balance during functional performance and gait. These findings support the use of PNF training programs as effective fall-prevention programs for the elderly.

한국 아동학대의 현실 (The Reality of Child Abuse in Korea)

  • 정규환;한호성;박도중;은석찬
    • Journal of Trauma and Injury
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    • 제25권4호
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    • pp.283-286
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    • 2012
  • A trauma surgeon is always concerned about child abuse when he or she meets injured children. Abused children will be neglected if trauma surgeons only concentrate on the injured site or physical dynamics. Lately, violence on children has increased in Korea. Therefore, in this study, we considered child abuse through a review of the literatures. An eleven-year-old boy visited the emergency room vomiting with abdominal distension. He had been kicked in the abdomen by his step-mother 10 days earlier. The computed tomography revealed a transected pancreas tail and neck with a large pesudocyst (Fig. 1) and laboratory findings showed an elevated amylase level of more than 6,500 IU/L. Because he complained of severe pain with rebound tenderness on the whole abdomen, he underwent an emergent laparotomy, a distal pancreatectomy of the tail portion with an anti-leakage procedure on the cut surface of the pancreas. However, he underwent a distal pancreatectomy again on the neck portion of the pancreas because of a continuing pseudocyst with severe pain that could not be controlled with conservative managements. After that, his symptoms were improved and he returned to his daily life.

Ron Arad의 디자인에 관한 연구 (A Study on the Designs of Ron Arad)

  • 서병기
    • 디자인학연구
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    • 제16권1호
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    • pp.199-208
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    • 2003
  • The Israel-born Ron Arad is one of Britain's "superstar" designers, an it has been said that he is Britain's answer to Philippe Starck. Arad is a highly individualistic designer whose ideas stem from a mental process that has more in common with that of the fine artist than of the jobbing designer for industry. His imagination expresses itself in the form of things. By the early 1990s he had become internationally recognized for his "ready-made" work. His furniture and lighting designs required extremely costly labour-intensive techniques to produce. As his work was highly evocative, suggesting a post-industrial world in which the urban landscape was characterized by materials in a state of decay. More recently, through collaborations with Italian and German manufactures, his work has reached a new level of sophistication and finish, which differentiates it from the earlier designs. As Arad reputation as a designer of workshop-based furniture came to an end and the era of "democratic" Arad furniture came into being. By middle of the decade he had become one of the most-discussed designers of the day. The spirituality that emanates from all his work is a product of his particular vision of the creative process, far removed from the typical, stereotyped trends in the sphere of modern industrialization. He goes one step further in his work by attempting to restore aesthetic dignity to the objects of daily life, in a search for beauty within the immediate environment.hin the immediate environment.

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Expression of Bacillus licheniformis $\alpha$-amylase Gene in Lactobacillus casei Strains

  • Kim, Jeong Hwan;Sung Hee Woo
    • Journal of Microbiology and Biotechnology
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    • 제5권5호
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    • pp.257-263
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    • 1995
  • As a first step for developing Lactobacillus strains capable of fermenting starch directly, the $\alpha$-amylase gene (amyL) from Bacillus licheniformis (Kim et al., 1988. Kor. J. Appl. Microbiol. Bioeng. 16: 369-373) was introduced into Lactobacillus casei strains and the level of $\alpha$-amylase expression in transformants was examined. 3 kb EcoRI fragments encompassing amyL were subcloned into the suitable lactococcal cloning vectors (pSA3, pMG36e, and p1L2530) and then recombinant plasmids were introduced into E. coli and L. casei strains by electroporation. Only one recombinant plasmid, $pIL2530\alpha$ was able to transform few L. casei strains tested at low efficiencies. The transformation efficiencies with the plasmid into L. casei YIT 9018 and L. casei A Tee 4646 were less than $10^2/\mu$ g pIL2530\alpha$. The level of amylase activities in L. casei was five to ten-fold lower than that in E. coli cells. $p1L2530\alpha$ was stably maintained in Lactobacillus strains in the presence of Em (5 $\mu $g/ml) but without antibiotic selection, it was unstable so more than 95$%$ of cells lost plasmids after a week of daily subculturing.

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강직성 척추염 환자의 통증이 수면장애에 미치는 영향: 피로의 매개효과를 중심으로 (The Effect of Pain in Patients with Ankylosing Spondylitis on Sleep Disturbance: Focusing on the Mediating Effect of Fatigue)

  • 조옥희;임종미;황경혜
    • 근관절건강학회지
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    • 제25권2호
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    • pp.104-111
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    • 2018
  • Purpose: The purpose of this study was to investigate the mediating effect of fatigue on the relationship between pain and sleep disturbance in patients with ankylosing spondylitis. Methods: The subjects of this study were 109 patients with ankylosing spondylitis who visited the rheumatology department in a university hospital. Subjects completed structured questionnaires measuring pain, sleep disturbance, and fatigue. Data were analyzed using t-test, Pearson's correlation coefficients, and 3-step regression analysis. Results: Pain was positively correlated with fatigue (r=.60, p<.001) and sleep disturbance (r=.45, p<.001). Fatigue was positively correlated with sleep disturbance (r=.55, p<.001) and had a mediating effect on the relationship between pain and sleep disturbance. Conclusion: The findings confirm that pain in patients with ankylosing spondylitis affects fatigue and its accumulation has a mediating effect on increasing the level of sleep disturbance. In clinical practice, education on symptom management for patients with ankylosing spondylitis needs to be provided for encouraging proper exercise and rest. Patient education should also include strategies to reduce fatigue and promote sleep in daily lives in addition to pain management.

근거 중심 치의학 1. 기초개념, 질문하기, 그리고 근거검색 (Evidence-Based Dentistry - 1. Basic Concepts, Question, and Searching)

  • 홍순민
    • 대한치과의사협회지
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    • 제45권2호통권453호
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    • pp.89-102
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    • 2007
  • Evidence-based dentistry is a new, worldwide trend in the field of clinical dentistry. Despite this fact, it has been neglected in Korean dental community. Thus, its basic concepts and the 5-step procedures are introduced and described in this 2-part series report. Evidence-based dentistry is a method of clinical practice where the clinicians use the best available research evidence for their own clinical decision making. By using this method, the clinical outcomes can be improved and the clinicians themselves can have the ability to keep watch over their daily practices. To clinically apply the principles of evidence-based dentistry, dental practitioners have to formulate a clear question, find the best available research evidence efficiently, critically appraise the evidence systematically, apply the results of the evidence to their practice, and evaluate the clinical outcomes comprehensively. In building a clinical question, it is essential to categorize questions according to their types followed by their organization using the key elements. Then, literature search must be done. There are many web sites for searching evidence, but PubMed is considered to be the leading site. To efficiently search the literature, search term must be selected appropriately and the search results should be limited.

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GIS AND WEB-BASED DSS FOR PRELIMINARY TMDL DEVELOPMENT

  • Choi, Jin-Yong;Bernard A. Engel;Yoon, Kwang-Sik
    • Water Engineering Research
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    • 제4권1호
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    • pp.19-30
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    • 2003
  • TMDL development and implementation have great potential fur use in efforts to improve water quality management, but the TMDL approach still has several difficulties to overcome in terms of cost, time requirements, and suitable methodologies. A well-defined prioritization approach for identifying watersheds of concern among several tar-get locations that would benefit from TMDL development and implementation, based on a simple screening approach, could be a major step in solving some of these difficulties. Therefore, a web-based decision support system (DSS) was developed to help identify areas within watersheds that might be priority areas for TMDL development. The DSS includes a graphical user interface based on the HTML protocol, hydrological models, databases, and geographic information system (GIS) capabilities. The DSS has a hydrological model that can estimate non-point source pollution loading based on over 30 years of daily direct runoff using the curve number method and pollutant event mean concentration data. The DSS provides comprehensive output analysis tools using charts and tables, and also provides probability analysis and best management practice cost estimation. In conclusion, the DSS is a simple, affordable tool for the preliminary study of TMDL development via the Internet, and the DSS web site can also be used as an information web server for education related to TMDL.

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Implementation of Subsequence Mapping Method for Sequential Pattern Mining

  • Trang Nguyen Thu;Lee Bum-Ju;Lee Heon-Gyu;Park Jeong-Seok;Ryu Keun-Ho
    • 대한원격탐사학회지
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    • 제22권5호
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    • pp.457-462
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    • 2006
  • Sequential Pattern Mining is the mining approach which addresses the problem of discovering the existent maximal frequent sequences in a given databases. In the daily and scientific life, sequential data are available and used everywhere based on their representative forms as text, weather data, satellite data streams, business transactions, telecommunications records, experimental runs, DNA sequences, histories of medical records, etc. Discovering sequential patterns can assist user or scientist on predicting coming activities, interpreting recurring phenomena or extracting similarities. For the sake of that purpose, the core of sequential pattern mining is finding the frequent sequence which is contained frequently in all data sequences. Beside the discovery of frequent itemsets, sequential pattern mining requires the arrangement of those itemsets in sequences and the discovery of which of those are frequent. So before mining sequences, the main task is checking if one sequence is a subsequence of another sequence in the database. In this paper, we implement the subsequence matching method as the preprocessing step for sequential pattern mining. Matched sequences in our implementation are the normalized sequences as the form of number chain. The result which is given by this method is the review of matching information between input mapped sequences.

뇌졸중 환자의 건측억제유도와 자기효능에 대한 이해 (Understanding the constraint induced movement and Self-efficacy in Stroke Patients)

  • 신형수;김중선
    • PNF and Movement
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    • 제3권1호
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    • pp.35-45
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    • 2005
  • Objectives : The purpose of this study was to understanding the constraint induced movement and Self-efficacy with arm training on upper motor function in Stroke Patients. Methods : Stroke, the leading cause of functional disability, causes a variety of impairments that compromise quality of life. Upper limb hemiparesis, a commonly seen impairment, is particularly problematic given its impact on activities of daily living. Because stroke was a disease to correspond to the first during domestic cause of death, and was accompanied by a lot of side aftereffects after a survival, stroke rehabilitation bought a patient and a family and a physical therapist, and it was main concern of. Results : Looks into upper extremity excrise of a subacute stroke patient estranged a acute convalescence later by a rehabilitation treatment in this consideration, and evaluates an effect to wind up constraint induced movement for an early treatment of stroke and Self efficacy, and help is one to an early rehabilitation of an stroke patient. Conclusions : Overuse sound tends after the stroke occurrence in the early stage in order to recompense for stroke, and at the time of a new aspect called learned nonuse syndrome by a movement of a paralysis part dusting off wealth with this step thing later. Constraint induced movement using self efficacy could be an effective for improving function of stroke.

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