• Journal of Digital Convergence
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• 제15권7호
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• pp.91-96
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• 2017

The purpose of this study is to evaluate the program for enhancing the interaction capacity between the child care institutions and the original family (associate) and propose a program suitable for the child care institutions. The program was conducted at two institution located in Seoul and Cheongju, and the process evaluation and outcome evaluation were conducted. First, the problems that appeared in the process evaluation were recruiting and maintaining participants. As a result of the satisfaction of each program, it was found that the satisfaction of the program sharing the various experiences or sharing the small daily life was high, and it was positive for the improvement of the relationship. Parents showed improvement in the post -test rather than the pre-test. Through qualitative assessment, positive evaluations were made in programs where the family participated in activities that could not be done together in the camp or everyday life, rather than just one-time activity programs.

• The Journal of Korean Academic Society of Nursing Education
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• 제10권1호
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• pp.84-93
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• 2004

Purpose: This study was conducted to investigate the subjective degree of fatigue, the degree of fatigue depending on constitution, and the factors related to fatigue in middle-aged women. Method: Data were collected from 51 patients, registered at Oriental Medicine Hospital in J-city and K-city respectively. The instrument used in this study were the Multidimensional Assessment of Fatigue and the Questionnaire of Sasang Constitution Classification Ⅱ. Data analysis was done SPSS Result: The characteristics of constitution in middle-aged women could be divided into three: twenty six people of Soeumin, thirteen people of Taeumin, and twelve people of Soyangin. The degree of fatigue in middle-aged women: the average score 30.61 out of the total score 40. Subdivision of fatigue scores: common fatigue degree 7.71, distress due to fatigue 7.67, degree of daily activity fatigue 7.43, and fatigue frequency in the previous week 7.84. There were significant differences in the degree of fatigue depending on constitution in middle-aged women(p=.033). This study revealed weight, exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Conclusion: In conclusion, fatigue is one of the difficult problems with middle-aged women. And this study revealed that change in the weight(especially loss of weight), physical exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Therefore it is necessary to develop Korean nursing intervention to providing an appropriate environment where there is the harmony of the dual principles of the negative and positive, and patients can be taken care of properly.

• The Korean Journal of Rehabilitation Nursing
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• 제13권2호
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• pp.140-150
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• 2010

Purpose: This study aims to find the factors that affect the degree of self-care performance in Parkinson's disease (PD) patients. Method: This study used a descriptive correlational design. The data were collected using a sample of 80 PD patients, from the university affiliated Parkinson Center in Busan. Pearson's correlations and multiple regression analyses were conducted using the SPSS 18.0. Results: The mean score of the self-care performance was 3.61 (${\pm}0.40$). The highest score observed of self-care performance subscale was medication subscale ($4.55{\pm}0.50$) and the lowest score was observed in the exercise subscale ($3.03{\pm}0.64$). The self-care performance had significant correlations with depression (r=-.32, p<.01), self-care knowledge (r=.28, p<.05), function of motion (r=.25, p<.05), ability of daily activity (r=.22, p<.05), self-efficacy (r=.24, p<.05), and support from medical staff (r=.24, p<.05). The significant predictors of self-care performance included depression (${\beta}=-.28$), status of employment (${\beta}=-.27$), self-care knowledge (${\beta}=-.21$), support from medical staff (${\beta}=-.28$), and educational level (${\beta}=-.28$), accounting for 34% of the variance in the self-care performance. Conclusion: Depression, self-care knowledge, medical support are significant predictors which affect the self-care performance with PD patients.

• Korean Journal of Social Welfare
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• 제59권1호
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• pp.223-249
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• 2007

This study is intended to investigate if the standard of vocational rehabilitation service could be solely determined by medical standard for disability definement and to find out what alternatives are available to resolve practical problems for those who are not identified as the severely disabled by the disability definement but do experience severe handicaps at work. Through the literature review, the researcher argued that the concept of 'functional limitation' would be a criteria, and thereby applied Modified Barthel Index to measure the degree of functional limitation. In view of researching the relationship among physical impairment, functional limitation, and job status based on 381 cerebral palsied, variables such as the type of cerebral palsy and the part of paralysis, have neither direct nor indirect influence to the job status; however, the pain and the mobility have indirect effects, and the ability of self-management has direct effect on the job status. The researcher concluded that future research about disabilities needs to provide a serious thought on what it is to be defined as 'disabilities', as well as to focus on further research conceptualizing the degree of physical 'functional limitation'.

• Proceedings of the Korean Society for Environmental Edudation Conference
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• 한국환경교육학회 2003년도 전반기 정기 학술발표대회 발표논문집
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• pp.50-56
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• 2003

＃1 The Education from our Environment, The urgent subject for survival and prosperity in the future. - Around Yamaguchi in japan. - ＃2 Days of tour : January, 15, 2003 - January, 28, 2003 ＊ Comprehensive classes involved in ecosystems; Ryojo Elementary school, Guina Elementary school, Dabusei Junior High School, Ube Technical High School, Yashiro Elementary School, Toyota Nishi Junior High School, Seii Elementary School, Yamaguchi Prefectural School for the Mentally Impaired, Yamaguchi Institute for Educational Research and In-service Training, Kirara Beach Nature Watching Park ＃3 Characteristics of Yamaguchi Prefectural Environmental Education - Constant effort by concerned authorities and dedicated teachers - Cooperation of schools with community - Application of the comprehensive classes - Student-centered education through experiences - Acquirement of basic knowledge on environment in their daily lives - The harmony with the ability to survive' ＃4 Characteristics of the environmental education in each school $\square$ Ryojo Elementary School \longrightarrow Breeding the fireflies' larvae and releasing them into nature $\square$ Kuina Elementary School \longrightarrow Keeping the rivers clean $\square$ Yashiro Elementary School \longrightarrow Learning through exploring ‘Akiyoshido Cave’ $\square$ Seii Elementary School \longrightarrow Tree-planting campaign continued for 30 years $\square$ Tabuse Junior High School \longrightarrow Making their village good to live in $\square$ Toyota-Nishi Junior High School \longrightarrow Learning through working on the farm and in the forests $\square$ Ube Technical High School \longrightarrow Purifying the pond by the ‘biotope’ ＃5 Focus on Yashiro Elementary School \longrightarrow Children Guide Activity (25 hours annually) * To love their native place and tourists' attraction, Akiyoshidal * To introduce a variety of local events; - To make a fire in the mountains - To explore the cave - To hold a festival for tourists - To have a family-jointed bike riding ＃6 $\square$ conclusion - Gradual extension of environmental education * individuals \longrightarrow school \longrightarrow community - Finding the environmental problems around themselves and relating them with features of their community < Tips for the environmental education in the future > - Need for encouragement of more lively discussion in class - Expansive application of comprehensive classes to various areas

• Journal of Sasang Constitutional Medicine
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• 제14권3호
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• pp.114-131
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• 2002

1. PURPOSE : The purpose of this study is to investigate the effect of Chungpyesagantang on LPS induced Arthritis in Mice. 2. METHOD : All the BALB/C Mice used in this study were 4wks of age at the start of the experiment. The experimental model of Arthritis was induced by injectection of $300{\mu}g/kg$ LPS in mice knee joint. The experiment was compare daily CS treatment group after Arthritis elicitation with Arthritis elicitated group at day 4, 7, 14 after Arthritis elicitation. 3. RESULTS 1) The hyperplasia of synoviocytes of CS treatment group after Arthritis elicitation is soften than Arthritis elicitated group. 2) The aggregation of collagen fibers CS treatment group after Arthritis elicitation is decreased than Arthritis elicitated group. 3) The distribution of TUNEL positive cells(apoptotic cell) of CS treatment group was remarkably increased than Arthritis elicitated group. 4) The distribution of $TNF-{\alpha}$, $NF-{\kappa}B\;p50$, COX-2 positive cells of CS treatment group after Arthritis elicitation in synovial membrane was decreased than Arthritis elicitated group. 5) The distribution of $IL-2R-{\alpha}$, ICAM-1 positive cells of CS treatment group after Arthritis elicitation in apical surface of synovial membrane was decreased than Arthritis elicitated group. 6) The distribution of $NF-{\kappa}B\;p50$, $IL-2R-{\alpha}$ in common iliac lymph node of CS treatment group after Arthritis elicitation positive cells was decreased than Arthritis elicitated group. 4. CONCLUSION : As a result of these experimental results, it may be concluded that Chungpyesagantang used for treatment of LPS induced Arthritis in Mice. Inflamation activity in CS treatment group after Arthritis elicitation was decreased than Arthritis elicitated group.

• Animal cells and systems
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• 제16권4호
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• pp.302-312
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• 2012

The purpose of this study was to examine whether Phellodendri Cortex extract (PCE) could improve learning and memory impairments caused by lipopolysaccharide (LPS)-induced inflammation in the rat brain. The effect of PCE on modulating pro-inflammatory mediators in the hippocampus and its underlying mechanism were investigated. Injection of LPS into the lateral ventricle caused acute regional inflammation and subsequent deficits in spatial learning ability in the rats. Daily administration of PCE (50, 100, and 200 mg/kg, i.p.) for 21 days markedly improved the LPS-induced learning and memory disabilities in the Morris water maze and passive avoidance test. PCE administration significantly decreased the expression of pro-inflammatory mediators such as tumor necrosis factor-${\alpha}$, interleukin-$1{\beta}$, and cyclooxygenase-2 mRNA in the hippocampus, as assessed by RT-PCR analysis and immunohistochemistry. Together, these findings suggest that PCE significantly attenuated LPS-induced spatial cognitive impairment through inhibiting the expression of pro-inflammatory mediators in the rat brain. These results suggested that PCE may be effective in preventing or slowing the development of neurological disorders, including Alzheimer's disease, by improving cognitive and memory function because of its anti-inflammation activity in the brain.

• Archives of Pharmacal Research
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• 제16권4호
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• pp.336-338
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• 1993

The immunomodulating activity of Kp, an antitumor protein-polysacchanide preparation from the shake-cultured mycelia of Phellinus linteus, was investigated in ICR mice subcutaneously implanted wit $1\times10^6$ cells of sarcoma 180. The mice were intraperitoneally administered with Kp at a does of 100 mg/kg once daily for five consecutive days starting from 24 hrs after the tumor implantation. Ten days after the last injection, the mice were immunized with $1\times10^7$ or $4\times10^8$ sheep red blood cells (SRBC) and five days later, the antibody-forming immune response were assessed by direct hemolytic plaque assay. To an immunization does of $1\times10^7$ SRBC, the Kp-treated mice elicied a successful humoral immune response despite the turmor-burden and produced $259\times10^3$ plaque-forming cells (PFC)/spleen, while the corresponding tumor-bearing control mice showed virtually no reponse $(2.0\times10^3$ PFC/spleen) (the stimulation index=129.5). However, to an immunization dose of $4\times10^8$ SRBC, both of the control mice and Kp-treated mice showed almost the same level of strong humoral immune response. From these data it is clear that Kp effectively restores the humoral immune response of the turmor-bearing ICR mice.

• The Korean Journal of Mycology
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• 제12권4호
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• pp.129-132
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• 1984

To find antitumor constituents in Korean basidiomycetes, the mycelia of Lentinus edodes DMC7, which had shown a good mycelial growth in shakeflasks, were cultured at $27^{\circ}C$ on an orbital shaking incubator at 180 rev/min for 12 days. The medium was composed of glucose (50g/l), yeast extract (9g/l), peptone (9g/l), and seven inorganic salts. A water soluble macromolecular fraction, LF-3, was obtained from the culure filtrate by fractionation with ethanol and dialysis using a Visking tube. When LF-3 was administered i.p. at 50mg/kg/day once daily for 10 consecutive days to female ICR mice which were implanted s.c. with sarcoma 180 $(10^6\;cells/mouse)$, it exerted a highly significant antitumor activity, with the tumor inhibition ratio of 53. 1%.

• Journal of Animal Science and Technology
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• 제60권11호
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• pp.28.1-28.6
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• 2018

Background: Preventing oxidative stress in heat stressed animals may be possible by increasing antioxidant defence via exogenous administration of antioxidant substrate and/or its precursors. The study aimed to investigate the effect of Soursop juice in mitigating oxidative stress induced by heat stress in rabbit. Methods: Sixty mixed breed rabbit bucks aged 12-18 months old with the average weight of $1826{\pm}8.35$ g/rabbit, randomly allotted to experimental treatments of four replicates each, in a completely randomized design during high-temperature humidity index in Ado Ekiti, Southwest Nigeria. Soursop juice (SSJ) was administered via oral drenched daily per kg body weight (BW), to designated treatment 1 to 5; $0.55mlkg^{-1}BW$ distilled water (control), $0.55mlkg^{-1}BW$ SSJ, $1.11mlkg^{-1}BW$ SSJ, $1.67mlkg^{-1}BW$ SSJ and $2.22mlkg^{-1}BW$ SSJ, respectively. Fastened blood samples were collected at days 28 and 56, and assay for serum protein, cholesterol, triglycerides, superoxide dismutase, catalase, reduced glutathione and lipid peroxidation using standard procedures. Result: Result revealed that SSJ demonstrated hypocholesterolemic effect in a dose-dependent manner throughout the study. Effect of chronic administration of SSJ to heat stressed rabbits proved beneficial, as SSJ reduced serum lipid peroxidation and enhanced antioxidant activity over 8 weeks. Conclusion: Administration of soursop juice to heat-stressed bucks at $2.22mlkg^{-1}BW$ offered optimum antioxidant defense against oxidative stress.