• Title/Summary/Keyword: d-ROM

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Improving International Access to the IARC Monographs Database with Linkage to other Sources of Information

  • Rice, Jerry M.;Waters, Michael D.;Wright, R.Glenn
    • Toxicological Research
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    • v.17
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    • pp.227-236
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    • 2001
  • The IARC Monographs Programme on the Evaluation of Carcinogenic Risks to Humans has reviewed, summarized and evaluated 869 environmental agents and exposures as oj June 2000. This large collection includes all relevant published epidemiological data on cancer in exposed humans and results of bioassays for carcinogenicity in experimental animals. Since 1986. cancer data have been systematically supplemented by summaries of other toxicological data that are relevant to assessments of carcinogenic hazard. These include summaries qf genetic and related effects of chemicals. which have been prepared as Genetic Activity Profiles (GAP) by the U.S. EPA in collaboration with IARC. As the Mono-graphs have proved increasingly valuable and influential worldwide. they have evolved into an encyclopedia on environmental carcinogenic risks to humans. However. the Monographs have historically been prepared only as printed books with limited distribution. and the Monographs Programme has needed to adjust to expectations oj wider availability. Since 1998 the evaluations and summaries have been globally accessible by Internet from IARC (http://www.iarc.fr) and the GAP profiles by Internet from EPA (http://www.epa.gov/gapdb/). with the two web sites linked. Improved EPN/ARC GAP database and software. GAP2000. now link GAP profiles directly to the appropriate IARC web pages for summaries of evaluations of a given compound and its overall IARC classification. During the year 2000. by means of optical character recognition (OCR) technology the entire series of IARC Monographs is being converted to an electronic version. The first edition is now available commercially in CD-ROM format and will soon become available on-line at .

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Kinematic Analysis of Dynamic Stability Toward the Pelvis-spine Distortion during Running (달리기 시 체간의 골반-척추구조변형이 동적안정성에 미치는 연구)

  • Park, Gu-Tae;Yoo, Kyoung-Seok
    • Korean Journal of Applied Biomechanics
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    • v.23 no.4
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    • pp.369-376
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    • 2013
  • The purposes of this study were to assess dynamic stability toward pelvis-spine column distortion during running and to compare the typical three-dimensional angular kinematics of the trunk motion; cervical, thoracic, lumbar segment spine and the pelvis from the multi-segmental spine model between exercise group and non-exercise group. Subjects were recruited as exercise healthy women on regular basis (group A, n=10) and non-exercise idiopathic scoliosis women (group B, n=10). Data was collected by using a vicon motion capture system (MX-T40, UK). The pelvis, spine segments column and lower limbs analysiaed through the 3D kinematic angular ROM pattern. There were significant differences in the time-space variables, the rotation motion of knee joint in lower limbs and the pelvis variables; obliquity in side bending, inter/outer rotation in twisting during running leg movement. There were significant differences in the spinal column that is lower-lumbar, upper-lumbar, upper-thoracic, mid-upper thoracic, mid-lower thoracic, lower thoracic and cervical spine at inclination, lateral bending and twist rotation between group A and group B (<.05, <.01 and <.001). As a results, group B had more restrictive motion than group A in the spinal column and leg movement behaved like a 'shock absorber". And the number of asymmetry index (AI) showed that group B was much lager unbalance than group A. In conclusion, non-exercise group was known to much more influence the dynamic stability of equilibrium for bilateral balance. These finding suggested that dynamic stability aimed at increasing balance of the trunk ROM must involve methods and strategies intended to reduce left/right asymmetry and the exercise injury.

Characteristics of the Compensation for Gait of the Induced Knee Stiffness in Normal Subjects (정상인 보행에서 무릎관절의 유도된 강직에 따른 신체 보상 특성)

  • Woo, Byung-Hoon
    • Korean Journal of Applied Biomechanics
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    • v.23 no.4
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    • pp.357-367
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    • 2013
  • The purposes of this study were investigated physical compensation for gait on induced knee stiffness in normal subjects. Ten subjects were participated in the experiment(age: $26.0{\pm}6.3$ yrs, height: $175.5{\pm}5.3$ cm, weight: $69.1{\pm}6.1$ kg). The study method adopted 3D analysis with five cameras and ground reaction force with two force-plate. Induced knee stiffness level were classified as gait pattern on ROM of knee(free level, $30^{\circ}$ restriction level, fix level). The results were as follows; In angular displacement of hip joint, left hip joint was the more extended in mid-stance on induced right knee stiffness. In angular displacement of knee joint, there was no physical compensation on induced right knee stiffness, but free knee level gait was more flexed in swing phase of right knee joint. In angular displacement of ankle joint, right ankle joint was the more dorsiflexed on induced right knee stiffness, and $30^{\circ}$ restriction level and fix level gait were less plantarflexed in TO2. In trunk tilt, free and $30^{\circ}$ restriction level gait was more backward tilt on induced right knee stiffness. In ROM of each joint, right knee joint was more larger and trunk tilt was more lower on induced right knee stiffness. In GRF, Fx was more bigger lateral force in free and $30^{\circ}$ restriction level gait, and was more bigger medial force in fix level gait. Fy was more bigger propulsion force in free level gait, and was was more bigger braking force in $30^{\circ}$ restriction level gait. Left braking force in $30^{\circ}$ restriction level gait was more bigger. Fz was no significant.

사용자 인터페이스 디자인과 개발 User Interface Design and development

  • 천진향
    • Archives of design research
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    • v.13 no.1
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    • pp.29-38
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    • 2000
  • Many computer system; (or program;) have been desigoc>d without taking their users needs into accOlmt To provide a practical and comprehensive introduction to the design and development of user interfaces, desigrer (or developer) is suggested to analyze and evaluate requirements from the view point of users and to design more effective program;. The su~ect of this thesis is to analyze and criticize tre details of Wonder-land, that is a demo multimedia ill-ROM title, in respect to User Interface Design and Development. By applying the coocepts, teclmiques and ideas to a real life study and analyzing and criticizing it from the view point of users, desigrer lets the program revised and developed by users. For User Interface Design and Development purposes this tresis analyzes and criticize the characteristics of the program already made, the current user interface design, mental models and users learning about the program. As a result it is founded that the program requires to be analyzing and criticizing continuously from a cognitive point of view to design and develop it successfully.

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Comparative Study on Biomechanical Behavior of Various Cervical Stand-Alone Cage Designs (경추용 일체형 추간체 유합 보형재의 디자인 변화에 따른 생체역학적 효과 비교 연구)

  • Park, Kwang Min;Jung, Tae Gon;Jeong, Seung Jo;Lee, Sung Jae
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.11
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    • pp.943-950
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    • 2016
  • The purpose of this study was to evaluate and compare by finite element analysis the biomechanical performance, in terms of cervical stand-alone cage screw insert angle (Type 3 - 5: 2 Screws) and screw arrangement (Type 6 and 7: 3 Screws / Type 8 and 9: 4 Screws), and the range of motion (ROM) of traditional anterior cervical discectomy of a fusion device (Type 1: Cage / Type 2: Cage + ACP). Our study suggests that the biomechanical behavior of a postoperative cervical spine could indeed be influenced by design features, such as screw angle and number of screws. In particular, ROM and the risk of subsidence were more sensitive during extension about type 5 (Insert Angle $20^{\circ}$). Our study also suggested that the number of screw asymmetries between up and down for type 6 and 7 could result in differences in the risk of screw fracture manifesting in different clinical aspects.

Intractable Pain Management by Combined Korean Medicine Treatment Including Acupotomy in Lumbar Disc Herniation: A Case Report (한방복합치료로 난치성 통증을 동반한 요추 추간판탈출증이 호전된 증례보고)

  • Choi, Hyeon Kyu;Lee, Young Rok;Cha, Hyun Ji;Sung, Ki Jung;Kim, Beom Seok;Kim, Min Ju;Lee, Ye Ji;Jeon, Ju Hyun;Kim, Young Il
    • Korean Journal of Acupuncture
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    • v.38 no.3
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    • pp.175-181
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    • 2021
  • A 57-year-old female diagnosed with L5-S1 lumbar intervertebral disc herniation, suffering from severe pain despite taking tapentadol received combined Korean medicine treatment, including acupotomy, acupuncture, pharmacopuncture, and herbal therapies for 53 days. To assess pain, Numeric Rating Scale (NRS) and lumbar range of motion (ROM) were checked daily from the day of admission. Moreover, the Oswestry Disability Index (ODI) and European Quality of Life-5 Dimensions (EQ-5D) were used to evaluate function and quality of life. After combined Korean medicine treatment, reabsorptioin of intervertebral disc was confirmed by radiological examination; pain reduced from NRS 5~7 to NRS 1~2; lumbar ROM in extention increased from 20° to 30°; and function and quality of life improved. The results suggest the possibility that a combined Korean medical treatment, including acupotomy, can be used as an alternative to opioids for pain management of lumbar vertebral disc herniation.

The Influence of Augmented Reality based Knee Exercise in Short Period on Range of Motion and Balance - Pilot study (증강현실 기반의 단기간 무릎운동이 관절가동범위와 균형에 미치는 영향 - 예비연구)

  • Im, JongHun;Yu, JaeHo
    • Archives of Orthopedic and Sports Physical Therapy
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    • v.14 no.2
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    • pp.1-8
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    • 2018
  • Purpose: This study investigated the effect of the augmented reality (AR)-based knee joint short period exercise program and used a motion analyzer with a 3D camera to determine the range of motion and dynamic balance and further investigate the effects of therapeutic exercise on patients. Methods: This study used AR-based motion analysis and a Y-balance test to measure the range of motion (ROM) of each joint: the hip joint and the knee joint. After the measurements, an exercise program was applied to the subjects, using the knee motion program function, and the muscles of the quadriceps femoris and the hamstring were stretched or strengthened. Results: Our results showed knee joint extension at the dominant hip joint flexion position. While there was no significant difference (p>.05) at this position, there were significant differences in the non-dominant hips, unbalanced knee joint flexion, and superior knee joint flexion (p<.05). The Y-balance test using the non-dominant leg supported by the dominant legs showed that the absolute reach was $69.70{\pm}7.06cm$ before the exercise, and the absolute reach after the exercise was $77.56{\pm}6.09cm$ (p<.05). Conclusions: There was a significant difference when the movement of the lower limbs supported the superior limbs, and a significant difference was found in the ROM when the non-dominant side supported the dominant side. Therefore, the AR-based exercise program improves the balance of the human body and the range of motion of the joints, and research that aims to improve patients abilities should continue.

Risk Factors of Musculoskeletal System in Automobile Manufacturing Workers with Mlid Intellectual Disabilities: Focus on Neck and Lower Back Regions (경도 지적장애 자동차제조업 근로자의 근골격계 위험 요인 조사 -목과 허리 부위 중점으로-)

  • Young-In Hwang;Du-Jin Park
    • PNF and Movement
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    • v.22 no.1
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    • pp.129-137
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    • 2024
  • Purpose: The aim of this study was to investigate and compare the risk factors focusing on the neck and lower back between general workers (GW) and mild intellectual disability workers (MIDW) in the automobile manufacturing industry. Methods: A total of 32 participants were required for this study design to achieve 80% power, 0.9 effect size, and an alpha level of 0.05. Each group consisted of 16 subjects, including GW and MIDW. Pain levels in the neck and lower back were measured for all participants using the visual analog scale (VAS). A dual digital inclinometer was used to measure the range of motion (ROM) in the neck and lower back three times, and the average was used for analysis. The independent t-test was used to compare between the wo groups. Cohen's d effect analysis was employed to determine the effect size. The significant level was set at 0.05. Results: In the MIDW, neck pain was significantly higher, and left cervical flexion was significantly decreased compared with the GW. There was no significant difference in lower back pain between the MIDW and GW. However, both lumbar flexion and extension, as well as lateral flexion, were significantly reduced in the MIDW compared with the GW. Conclusion: This study reveals that MIDW working in the automobile manufacturing industry have a greater risk of neck pain, limitation in left cervical flexion, and overall restriction in the ROM of the lower back compared with GW.

Adult Proximal Humeral Locking Plate Is a Good Alternative Option in the Treatment of Adolescent Subtrochanteric Femur Fractures: A Case Series and Literature Review

  • Ceyhun Caglar;Serhat Akcaalan;Merve Bozer;Mustafa Akkaya
    • Hip & pelvis
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    • v.34 no.4
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    • pp.245-254
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    • 2022
  • Purpose: Management of pediatric subtrochanteric femur fractures (SFFs) is difficult. The aim of this study was to evaluate the outcomes of adolescent SFFs treated with adult proximal humeral locking plates (PHLPs). Materials and Methods: A retrospective analysis of 18 adolescents (11 male, 7 female) with a diagnosis of SFF who underwent internal fixation with a PHLP was conducted. Data regarding injury mechanism, fracture pattern, and time to union were recorded for all patients. In addition, a clinical and functional evaluation of patients was performed using the Harris hip score (HHS), Iowa hip score (IHS), modified Merle d'Aubigne-Postel score (MMAPS), Flynn criteria, and hip range of motion (ROM). Results: The mean age of the patients was 12.72±2.05 years (range, 10-16 years). Radiological observation was performed for evaluation of five different injury mechanisms and different fracture patterns in patients. The mean postoperative HHS was 92.27±5.61, the mean IHS was 90.88±6.46, and the mean MMAPS was 17.22±0.94. According to the Flynn criteria, excellent results were achieved in 14 cases and satisfactory results were obtained in four cases. Measurements of the patients' mean hip ROM values were as follows: 17.77±3.52° in extension, 115.27±6.74° in flexion, 43.05±3.48° in abduction, 27.50±4.28° in adduction, 42.22±4.60° in internal rotation, and 42.22±3.91° in external rotation. Conclusion: Surgery performed on adolescent patients using an adult PHLP showed good, safe results. Therefore, it should be considered as an alternative option.

Effect of The Daoyin Exercise Therapy Combined with Complex Korean Medicine Treatment on Pain and Function Improvement of Low Back Pain Patients : A Retrospective Observational Study (한방복합치료를 병행한 도인운동요법이 요통환자의 통증 및 기능 개선에 미치는 영향 : 후향적 관찰 연구)

  • Choi, Bong Seok;Lee, Eun Jung;Li, Yu Chen;Lee, Jung Min;Kim, Eun Seok;Song, Gwang Chan;Jung, In Chul;Oh, Min Seok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.32 no.1
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    • pp.88-97
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    • 2018
  • This study was designed to prove the effect of the Daoyin exercise therapy combined with complex korean medicine treatment on pain and function improvement of low back pain patients. A retrospective observational study. 30 low back pain patients, checked numeric rating scale(NRS) over 5, were treated with the Daoyin exercise therapy combined with complex korean medicine treatment. NRS, roland & morris disability questionnaire(RMDQ), range of motion(ROM), isokinetic muscle strength, and euroqol five demension questionnaire(EQ-5D) were checked to evaluate patients. The Daoyin exercise therapy combined with complex korean medicine treatment reduced NRS $5.67{\pm}1.40$ to $3.73{\pm}1.72$, improved RMDQ $10.33{\pm}4.91$ to $8.17{\pm}5.40$, strengthened lumbar muscle's peak torque and improved EQ-5D $0.56{\pm}0.20$ to $0.63{\pm}0.15$ and euroqol visual analogue scale(EQVAS) $46.80{\pm}19.95$ to $57.50{\pm}19.93$ but had no effect on ROM. NRS decreased significantly as the number of trials increased. No one had serious adverse reactions. As described above, the Daoyin exercise therapy combined with complex korean medicine treatment can help reducing low back pain, improving lumbar function, strengthening lumbar muscle power and stamina and improving quality of life of low back pain patients.