• 대한방사성의약품학회지
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• 제9권1호
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• pp.3-8
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• 2023

Parkinson's disease is a neurodegenerative disease caused by damage to brain neurons related to dopamine. Non-clinical animal models mainly used in Parkinson's disease research include drug-induced models of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 6-hydroxydopamine, and genetically modified transgenic animal models. Parkinson's diagnosis can be made using brain imaging of the substantia nigra-striatal dopamine system and using a radiotracer that specifically binds to the dopamine transporter. In this study, ¹⁸F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane was used to confirm the image evaluation cutoff between normal and parkinson's disease models, and to confirm model persistence over time. In addition, the efficacy of single or combined administration of clinically used therapeutic drugs in parkinson's animal models was evaluated. Image analysis was performed using the PMOD software. Converted to standardized uptake value, and analyzed by standardized uptake value ratio by dividing the average value of left striatum by the average value of right striatum obtained by applying positron emission tomography images to the atlas magnetic resonance template. The image cutoff of the normal and the parkinson's disease model was calculated as SUVR=0.829, and it was confirmed that it was maintained during the test period. In the three-drug combination administration group, the right and left striatum showed a high symmetry of more than 0.942 on average and recovered significantly. Images using ¹⁸F-N-(3-fluoropropyl)-2β-carboxymethoxy-3β-(4-iodophenyl) nortropane are thought to be able to diagnose and evaluate treatment efficacy of non-clinical Parkinson's disease.

• 대한기계학회논문집
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• 제18권4호
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• pp.920-932
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• 1994

The combustion phenomena of a reciprocating engine is one of the most important processes affecting performance and emissions. One effective way to improve the engine combustion is to control the motion of the charge inside a cylinder by means of optimum induction system design, because the flame speed is mainly determined by the turbulence at compression(TDC) process in S.I. engine. It is believed that the tumble and swirl motion generated during intake breaks down into small-scale turbulence in the compression stroke of the cycle. However, the exact nature of their relationship is not well known. This paper describes cycle resolved LDV measurement of turbulent flow inside the cylinder of a 4-valve engine under motoring(non-firing) conditions, and studies the effect of intake port configurations on the turbulence characteristics using following parameters ; Eulerian temporal autocorrelation coefficient, turbulence energy spectral density function, Taylor micro time scale, integral time scale, and integral length scale.

• 디지털산업정보학회논문지
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• 제17권3호
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• pp.121-132
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• 2021

The purpose of this study is to explore ways to improve the quality of real-time video lectures in a non-face-to-face environment using IPA (Importance-Performance Analysis). Recently, due to the impact of COVID-19 in universities, all remote classes are being implemented, so research is needed to raise learner awareness. Accordingly, factor analysis, mean analysis, correspondence analysis, and IPA analysis were performed based on the data of 632 students who responded from March 21 to June 30, 2021 for learners of K University in Chungbuk. First, overall satisfaction was low compared to importance, and the difference in system perception was the largest. Second, the difference in learner perception of real-time video lectures through the IPA matrix showed that the system error and screen cutoff were the largest. Third, the difficulty of lecture content, task and test feedback, etc. are classified. Accordingly, the satisfaction of real-time video lectures in non-face-to-face environments is low, suggesting that school-level support for quality improvement to improve learner satisfaction in non-face-to-face environments and the role of instructors are needed to improve learners' academic achievement.

• 대한공간정보학회지
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• 제9권1호
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• pp.59-66
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• 2001

GPS/GLONASS 결합을 통해 위성의 가시성, 정확성, 그리고 이용성 등이 증가하였다. 하지만 두 시스템 결합에서 시간계 차이, 좌표계 차이, 그리고 GLONASS의 상이한 주파수에 의해 결합 반송파 주파수에서 반송파 미지정수 결정에 관한 문제점을 가지고 있다. 따라서 본 연구에서는 단독위치결정에서 GPS/GLONASS 결합에 의한 위치결정 정확도를 평가하고, GPS/GLONASS 결합에 의한 위성의 가시성과와 위성신호 수신고도각에 따른 자료획득율을 검토함으로써 GPS/GLONASS 결합 특성을 알아보고자 한다.

• 전자공학회논문지D
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• 제35D권1호
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• pp.34-40
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• 1998

For applicating to 10-Gbit/s optical transimission systems, we have designed and fabricated a laser driver IC with extremely-high-operation-frequencies using AlGaAs/GaAs heterojunction bipolar transistors (HBTs), and have investigated its performances. Circuits design andsimulation were performed using SPICE and LIBRA. A discrete AlGaAs/GaAs HBT with the emitter area of 1.5*10 .mu.m$^{2}$, used for the circuit fabrication, exhibited cutoff frequency of 63 GHz andmaximum osciallation frquency of 50 GHZ. After fabrication of MMICs, we observed the very wide bandwidth of DC~18 GHz and the S$_{21}$ gain of 17 dB for a laser driver IC from the on-wafer measurement. Metal-packaged laser driver IC showed the excellent eye opening, the modulation currents of 32 mA, the rise/fall time of 40 ps, measured at the data rates of 10-Gbit/s.

• 한국안전학회지
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• 제6권2호
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• pp.21-30
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• 1991

In this paper, we study effect of waveness at the optical surface roughness measurement. In generally, waveness components cause errors in calculation of the roughness value of metal surface. We study about surface roughness signals In the frequency domain for separate two signal component of real roughness and waveness by digital signal processing methods. Thereafter, determine low and high Component of frequency spectrum. By this separating frequency value we design liner low and high pass filter which cutoff frequency is 1 Hz. After this process, converted each filtered spectrum by inverse discrete fourier transformation to time domain waveness and real roughness signals We calculate surface roughness value from filtered roughness signals. For evaluate this method, we use five specimens roughness signal which obtained from optical surface roughness measuring system in 3mm/s moving speed with 0.1 mm laser beam spot size As a result, we obtain more linerized roughness value than that of unfiltered roughness signals.

• 한국환경과학회지
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• 제13권11호
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• pp.993-1000
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• 2004

As an effort to clarify the ecosystem of Osaka Bay, a semi-enclosed coastal area under the influence of stratification, a three-dimensional water quality model with combination of the baroclinic flow model and primitive eco-system model was constructed. The proposed model succeeded in simulating the time-depending flow and density structure and the baroclinic residual currents in Osaka Bay. In present study, we tried to improve the model by taking account of the benthic-pelagic interaction and exchange of nutrients between sea bottom sediments and overlaying water. On vertical structure, the model consists of 13 layers of water and eight layers of sediments. Long-term prediction of water quality was conducted from 1964 to 1985. This period is characterized by rapid water pollution and its decrease by the cutoff reduction of COD and P flowed into Osaka Bay. By combining the sediment model into original model, the numerical model was confirmed to shows more reasonable results in simulating the water quality in Osaka Bay.

• 기술사
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• 제32권6호
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• pp.148-157
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• 1999

As cultural Heritages are source of the national history and a life transition, their extinction is a fatal shock as result of cutoff the genealogy of the creative national spirit. So, we have necessarily to protect them, and to get the duty and the responsibility which the cultural inheritance hands over tnem to descendants with preserving and meaning safely at present time. In these days, the risk of fire in the Cultural Heritages building is increased because of rash changing environments from the indiscreet development of them. Accordingly, in order to get the original transmission of the Cultural Heritages, this paper involves being intensive the fire safety information of the Cultural Heritage in kyonggi-do province, analyzing their diagnoses, and studying a Fire Safety Prevention Management model to protect and to maintain them continuously. Therefore, it is to contribute from this approach to collecting fire safety information, analyzing diagnostic problems in fire accidents, and to manage the prevention method for protecting and maintaining the Cultural Heritages.

• The Journal of the Acoustical Society of Korea
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• 제21권2E호
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• pp.91-97
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• 2002

One of the most important things in mobile phone service is Hand-Off (H/O). Meantime soft H/O and softer H/O have been used between the same generations (2G↔2G) and there is little problem. With user's needs and the development of communication technology, the system with different generation coexists and pilot beacon and time-periodic beacon are used for H/O between generations (2.5G↔2G) to start service, but it is not economic and efficient. To improve such problems, ENHHO developed in April 2001 has recently used. Unfortunately, this method also has the defect of momentary cutoff of communication information during the procedure of H/O in case of more than 5 pilot signals. Accordingly, we suggest algorithm to improve the problem of ENHHO and examines its propriety by analyzing the results of field survey using the algorithm.

• Journal of information and communication convergence engineering
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• 제10권1호
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• pp.5-10
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• 2012

The cyber class has many advantages because it removes the limitations of sharing the same time and space of a class in a classroom. However, most instructors still hesitate to use it because it is more vulnerable to academic misconduct than a faceto- face class. To overcome this problem, we identified suspected cheaters out of a group of test-takers through several objective data, and verified whether or not the suspects were actually cheaters. By investigating the status of academic cheating, we also implement our assessment system with Skinner’s reinforcement theory in order to eliminate or reduce cyber misconducts.