• Archives of Plastic Surgery
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• 제38권5호
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• pp.567-575
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• 2011

Purpose: Acellular human dermis is very useful implant for use in plastic and reconstructive surgery. However, the volume of acellular human dermis graft is known to decrease for a long time. Basic fibroblast growth factor (bFGF) is a polypeptide that enhances the collagen synthesis and angiogenesis. In the current study we examined whether bFGF could improve the survival of acellular human dermis ($SureDerm^{(R)}$) by increasing angiogenesis of the graft. Methods: Forty rats were divided into two groups (control and bFGF). A 2-mm thick piece of $SureDerm^{(R)}$ was cut into smaller pieces that were $15{\times}5$ mm in size. Two subcutaneous pockets were made on the back of each rat. Grafts sprayed with bFGF were implanted in the bFGF group and injected with bFGF after transplantation every 3 days for 2 weeks. In the control group, the grafts were treated with phosphate-buffered saline (PBS) instead of bFGF. Four days, and 1, 4, and 12 weeks after the implantation, the grafts were harvested and gross and histologic examinations were performed. Inflammation grade, graft thickness, neocollagen density, and neocapillary count were measured. Results: The bFGF group displayed more rapid accumulation of inflammatory cells with a higher density of neocapillaries, and increased active collagen synthesis. After 12 weeks, the thickness of the grafts in the control and bFGF groups was $75.15{\pm}4.80%$ and $81.79{\pm}5.72%$, respectively, in comparison to the thickness before transplantation. There was a statistically significant difference between both groups ($p$ <0.05). Conclusion: bFGF was effective in reducing the absorption of acellular human dermal grafts by increasing angiogenesis and accelerating engraftment. In conclusion, bFGF may be a good tool for use in acellular human dermal graft transplantation for reconstructive surgery involving soft-tissue defects.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.322-322
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• 2010

For boron doping on n-type silicon wafer, around $1,000^{\circ}C$ doping temperature is required, because of the relatively low solubility of boron in a crystalline silicon comparing to the phosphorus case. Boron doping by fiber laser annealing and lamp furnace heat treatment were carried out for the uniformly deposited p-a-Si:H layer. Since the uniformly deposited p-a-Si:H layer by cluster is highly needed to be doped with high temperature heat treatment. Amorphous silicon layer absorption range for fiber laser did not match well to be directly annealed. To improve the annealing effect, we introduce additional lamp furnace heat treatment. For p-a-Si:H layer with the ratio of $SiH_4:B_2H_6:H_2$=30:30:120, at $200^{\circ}C$, 50 W power, 0.2 Torr for 30 min. $20\;mm\;{\times}\;20\;mm$ size fiber laser cut wafers were activated by Q-switched fiber laser (1,064 nm) with different sets of power levels and periods, and for the lamp furnace annealing, $980^{\circ}C$ for 30 min heat treatment were implemented. To make the sheet resistance expectable and uniform as important processes for the $p^+$ layer on a polished n-type silicon wafer of (100) plane, the Q-switched fiber laser used. In consequence of comparing the results of lifetime measurement and sheet resistance relation, the fiber laser treatment showed the trade-offs between the lifetime and the sheet resistance as $100\;{\omega}/sq.$ and $11.8\;{\mu}s$ vs. $17\;{\omega}/sq.$ and $8.2\;{\mu}s$. Diode level device was made to confirm the electrical properties of these experimental results by measuring C-V(-F), I-V(-T) characteristics. Uniform and expectable boron heavy doped layers by fiber laser and lamp furnace are not only basic and essential conditions for the n-type crystalline silicon solar cell fabrication processes, but also the controllable doping concentration and depth can be established according to the deposition conditions of layers.

• Journal of Welding and Joining
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• 제30권4호
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• pp.44-48
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• 2012

H-beam used for stiffening the upper structure of ocean plant is cut in the various shapes. The cutting process of the H-beam is done manually and requires a long time and high cost. Therefore, automation of H-beam cutting is an important task. This research aims to develop a 3-D simulator to build the automatic H-beam cutting system and to determine the optimal cutting method. The automatic H-beam cutting system composes of 6 robots including 2 cutting robots hang to a crane and 1 conveyer. The appropriate system layout for covering the various sizes and types of H-beam was tested and determined using the simulator. The H-beam cutting system uses a hybrid type of plasma and gas cutting because of special cutting shapes of H-beam. The cutting area of each cutting method should be properly divided according to the size and shape of H-beam to shorten the total cutting time. Additionally the collision between a robot and a robot or a robot and H-beam should be avoided. The optimal cutting method for the shortest cutting time without the collision could be found for the various cutting conditions by use of the simulator. 2 simulation samples shows the availability of the simulator to find the optimal cutting method.

• 화훼연구
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• 제18권1호
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• pp.66-72
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• 2010

본 실험은 절화장미 중 만개시의 꽃의 크기, 밀집도, 개화 시 꽃의 모양, 꽃잎의 단아함, 염색 시 색발현 등이 양호한 'Akito' 품종을 대상으로 단색염색을 위한 최적조건을 규명하고자 실시하였다. 염료용액의 pH가 3.5, 염료의 온도가 $20-25^{\circ}C$일 때 염료의 착색과 흡수속도가 가장 빨랐으며 절화수명 또한 15일로 가장 길었다. 염색을 위한 꽃의 개화 정도는 꽃잎이 3장 이상 핀 상태인 2~3단계에서 Pantone color, 염색 후 꽃의 품질및 절화수명이 양호하였다. 염색액의 처리 시 실내온도는 $10^{\circ}C$의 비교적 저온에서 흡수가 양호하였다. 염색용액의 농도는 $10g{\cdot}L^{-1}$ 처리했을 때 가장 선명한 색상을 나타내었으며 염색액의 흡수를 촉진시키기 위한 전착제 처리는 $2mL{\cdot}L^{-1}$를 사용하는 것이 가장 적절한 것으로 판단된다.

• 한국광학회지
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• 제1권1호
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• pp.46-51
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• 1990

Soft X-ray는 자연상태의 생물체를 높은 대비(high contrast)의 영상으로 관찰할 수 있는 광원이다. 1GW급의 광분해 옥소레이저 ($\lambda$=1.315$\mu\textrm{m}$, E=12.7J)를 몰리브덴(Mo) 표적에 집속시켜 플라즈마를 발생시켰으며 플라즈마에서 방출되는 넓은 파장 영역의 연속스펙트럼을 0.1$\mu\textrm{m}$ 두께의 알루미늄 필터를 거치게 하여 soft X-ray 영역에 중심세기를 갖는 광원을 얻었다. X-ray용 resist로 감도가 좋은 PBS를 사용하여 그물망(mesh), 거미줄, 적혈구의 replica를 얻었다. 본해능에 미치는 두 가지의 주된 영향인 광원의 크기에 의한 영향과 Fresnel 회절효과를 고찰하고 실험결과를 비교하였다. 본 실험에서는 0.1$\mu\textrm{m}$이하의 분해능을 얻었다.

• Journal of the Korean Wood Science and Technology
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• 제47권5호
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• pp.547-556
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• 2019

Thinned, small larch logs have small diameters and no value-added final use, except as wood chips, pallets, or fuel wood, which are products with very low economic value; however, their mechanical strength is suitable for structural applications. In this study, small larch logs were sawed, dried, and cut into square timbers (with a $90mm{\times}90mm$ cross section) that were laterally glued to form core panels used to manufacture cross-laminated timber (CLT) wall panels. The surface and back of these core panels were covered with 12-mm-thick structural plywood panels, used as cross bands to obtain three-ply CLT wall panels. This attachment procedure was conducted in two different ways: gluing and pressing (CGCLT) or gluing and nailing (NGCLT). The size of the as-manufactured CLT panels was $1,220mm{\times}2,440mm$, the same as that of the plywood panels. The final wall panels were tested under lateral shear force in accordance with KS F 2154. As the lateral load resistance test required $2,440mm{\times}2,440mm$ specimens, two CLT wall panels had to be attached in parallel. In addition, the final CLT panels had tongued and grooved edges to allow parallel joints between adjacent pieces. For comparison, conventional light-frame timber shear walls and midply wall systems were also tested under the same conditions. Shear walls with edge nail spacing of 150 mm and 100 mm, the midply wall system, and the fabricated CGCLT and NGCLT wall panels exhibited maximum lateral resistances of 6.1 kN/m (100%), 9.7 kN/m (158%), 16.9 kN/m (274%), 29.6 kN/m (482%), and 35.8 kN/m (582%), respectively.

• Nutrition Research and Practice
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• 제13권3호
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• pp.205-213
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• 2019

BACKGROUND/OBJECTIVES: Myocardial infarction (MI) is caused by extensive myocardial damage attributed to the occlusion of coronary arteries. Our previous study in a rat model of ischemia/reperfusion (I/R) demonstrated that administration of arabinoxylan (AX), comprising arabinose and xylose, protects against myocardial injury. In this study, we undertook to investigate whether psyllium seed husk (PSH), a safe dietary fiber containing a high level of AX (> 50%), also imparts protection against myocardial injury in the same rat model. MATERIALS/METHODS: Rats were fed diets supplemented with PSH (1, 10, or 100 mg/kg/d) for 3 d. The rats were then subjected to 30 min ischemia through ligation of the left anterior descending coronary artery, followed by 3 h reperfusion through release of the ligation. The hearts were harvested and cut into four slices. To assess infarct size (IS), an index representing heart damage, the slices were stained with 2,3,5-triphenyltetrazolium chloride (TTC). To elucidate underlying mechanisms, Western blotting was performed for the slices. RESULTS: Supplementation with 10 or 100 mg/kg/d of PSH significantly reduces the IS. PSH supplementation (100 mg/kg/d) tends to reduce caspase-3 generation and increase BCL-2/BAX ratio. PSH supplementation also upregulates the expression of nuclear factor erythroid 2-related factor 2 (NRF2), and its target genes including antioxidant enzymes such as glutathione S-transferase mu 2 (GSTM2) and superoxide dismutase 2 (SOD2). PSH supplementation upregulates some sirtuins ($NAD^+$-dependent deacetylases) including SIRT5 (a mitochondrial sirtuin) and SIRT6 and SIRT7 (nuclear sirtuins). Finally, PSH supplementation upregulates the expression of protein kinase A (PKA), and increases phosphorylated cAMP response element-binding protein (CREB) (pCREB), a target protein of PKA. CONCLUSIONS: The results from this study indicate that PSH consumption reduces myocardial I/R injury in rats by inhibiting the apoptotic cascades through modulation of gene expression of several genes located upstream of apoptosis. Therefore, we believe that PSH can be developed as a functional food that would be beneficial in the prevention of MI.

• 천문학회보
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• 제44권1호
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• pp.54.2-54.2
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• 2019

Removing noise which occurs inevitably when taking image data has been a big concern. There is a way to raise signal-to-noise ratio and it is regarded as the only way, image stacking. Image stacking is averaging or just adding all pixel values of multiple pictures taken of a specific area. Its performance and reliability are unquestioned, but its weaknesses are also evident. Object with fast proper motion can be vanished, and most of all, it takes too long time. So if we can handle single shot image well and achieve similar performance, we can overcome those weaknesses. Recent developments in deep learning have enabled things that were not possible with former algorithm-based programming. One of the things is generating data with more information from data with less information. As a part of that, we reproduced stacked image from single shot image using a kind of deep learning, conditional generative adversarial network (cGAN). r-band camcol2 south data were used from SDSS Stripe 82 data. From all fields, image data which is stacked with only 22 individual images and, as a pair of stacked image, single pass data which were included in all stacked image were used. All used fields are cut in $128{\times}128$ pixel size, so total number of image is 17930. 14234 pairs of all images were used for training cGAN and 3696 pairs were used for verify the result. As a result, RMS error of pixel values between generated data from the best condition and target data were $7.67{\times}10^{-4}$ compared to original input data, $1.24{\times}10^{-3}$. We also applied to a few test galaxy images and generated images were similar to stacked images qualitatively compared to other de-noising methods. In addition, with photometry, The number count of stacked-cGAN matched sources is larger than that of single pass-stacked one, especially for fainter objects. Also, magnitude completeness became better in fainter objects. With this work, it is possible to observe reliably 1 magnitude fainter object.

• 방송공학회논문지
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• 제24권2호
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• pp.234-242
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• 2019

본 논문에서는 일정 크기로 자른 영상의 가운데 픽셀이 SIFT 특징점인지를 판별함으로써 SIFT 특징점을 추출하는 딥 뉴럴 네트워크(Deep Neural Network)를 제안한다. 이 네트워크의 데이터 세트는 DIV2K 데이터 세트를 $33{\times}33$ 크기로 잘라서 구성하고, 흑백 영상으로 판별하는 SIFT와는 달리 RGB 영상을 사용한다. 그라운드 트루스(ground truth)는 옥타브(scale, octave)를 0, 시그마(sigma)는 1.6, 간격(intervals)은 3으로 설정하여 추출한 RobHess SIFT 특징들로 구성한다. VGG-16을 기반으로 컨볼루션 층을 13개에서 23개와 33개로 점점 깊은 네트워크를 구성하고, 영상의 스케일을 증가시키는 방법을 바꿔가며 실험을 수행한다. 출력 층의 활성화 함수로 시그모이드(sigmoid) 함수를 사용한 결과와 소프트맥스(softmax) 함수를 사용한 결과를 비교하여 분석한다. 실험결과 제안한 네트워크가 99% 이상의 추출 정확도를 가질 뿐 아니라 왜곡된 영상에 대해서도 높은 추출 반복성을 가진다는 것을 보인다.

• Journal of Korean Neurosurgical Society
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• 제64권4호
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• pp.585-591
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• 2021

Objective : Filum transection is one of the most commonly performed operative procedure in pediatric neurosurgery. However, the clinical and pathological features as well as the surgical indication are not well-established. This study aimed to analyze the characteristics of patients who underwent transection of the filum during the last 10 years in a single institute. Methods : A total of 82 patients underwent transection of the filum during the period. As a general rule, we performed the transection in patients who are symptomatic or have abnormality in the urologic or neuromuscular evaluations. There were exceptions as asymptomatic patients who only fit the definition of thickened filum (width greater than 2.0 mm or conus level below L3 vertebral body) were operated by parent's wish or surgeon's preference according to radiological findings, etc. Results : Seventy-six out of 82 patients had fibrous tissue in the pathologic specimen of filum. Interestingly, patients who had glial cells were more correlated with no preoperative syrinx, and no progression of syrinx even for those who did have syrinx initially. Also, larger percentage of symptomatic patients had peripheral nerve twigs than asymptomatic patients. No difference in conus level or thickness of filum was found between patients with or without preoperative syrinx. Significantly more patients with syrinx (56%) were chosen to be operated without any symptom or abnormality in study i.e., solely based on radiological findings than those without syrinx (21%). The surgical outcome for syrinx was favorable, as all but one patient had either improved or static syrinx. The exceptional case had increase in size due to the upward displacement of the proximal end of the cut filum. Conclusion : This study evaluated the pathological, clinical, radiological features of patients who underwent transection of the filum. Interesting correlations between pathological findings and clinical features were found. Excellent outcome regarding preoperative syrinx was also shown.