• Molecules and Cells
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• v.39 no.4
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• pp.322-329
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• 2016

Voltage-gated $Ca^{2+}$ ($Ca_V$) channels are dynamically modulated by Gprotein-coupled receptors (GPCR). The $M_1$ muscarinic receptor stimulation is known to enhance $Ca_V2.3$ channel gating through the activation of protein kinase C (PKC). Here, we found that $M_1$ receptors also inhibit $Ca_V2.3$ currents when the channels are fully activated by PKC. In whole-cell configuration, the application of phorbol 12-myristate 13-acetate (PMA), a PKC activator, potentiated $Ca_V2.3$ currents by ~two-fold. After the PMA-induced potentiation, stimulation of $M_1$ receptors decreased the $Ca_V2.3$ currents by $52{\pm}8%$. We examined whether the depletion of phosphatidylinositol 4,5-bisphosphate ($PI(4,5)P_2$) is responsible for the muscarinic suppression of $Ca_V2.3$ currents by using two methods: the Danio rerio voltage-sensing phosphatase (Dr-VSP) system and the rapamycin-induced translocatable pseudojanin (PJ) system. First, dephosphorylation of $PI(4,5)P_2$ to phosphatidylinositol 4-phosphate (PI(4)P) by Dr-VSP significantly suppressed $Ca_V2.3$ currents, by $53{\pm}3%$. Next, dephosphorylation of both PI(4)P and $PI(4,5)P_2$ to PI by PJ translocation further decreased the current by up to $66{\pm}3%$. The results suggest that $Ca_V2.3$ currents are modulated by the $M_1$ receptor in a dual mode-that is, potentiation through the activation of PKC and suppression by the depletion of membrane $PI(4,5)P_2$. Our results also suggest that there is rapid turnover between PI(4)P and $PI(4,5)P_2$ in the plasma membrane.

• Proceedings of the KSRS Conference
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• 2009.03a
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• pp.167-171
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• 2009

정지궤도에서는 세계 최초의 해양관측위성으로 개발된 정지궤도 해양위성(GOCI, Geostationary Ocean Color Imager)은 통신해양기상위성(COMS, Communication, Ocean and Meterological Satellite)의 탑재체로서 2009년말 발사 예정이다. 정지궤도 해양위성의 복사보정은 센서의 전기적 특성에 의한 잡음을 제거하기 위한 암흑전류 교정(Dark Current Correction)을 먼저 수행한 다음, 주운영지상국인 해양위성센터(KOSC, Korea Ocean Satellite Center)에서 수신된 위성의 원시자료의 Digital Number(DN)를 실제 해양원격탐사에서 이용하는 물리량인 복사휘도(Radiance, $W/m^2/{\mu}m/sr$)로 변환하는 복사보정을 수행한다. 정확도 높은 복사보정을 수행하기 위해서는 기준광원의 복사휘도와 센서의 물리적 특성을 정확하게 알아야 한다. 정지궤도 해양위성 궤도상 복사보정(on-orbit radiometric calibration)에서는 태양이 기준광원이기 때문에, 기준 태양복사모델(Thuillier 2004 Solar Irradiance Model)에서 지구-태양간 거리 변화(1년 주기)를 보정한 태양의 방사도 (Irradiance)를 이용하고, 태양입사각에 대한 태양광 확산기의 감쇄 특성 변화를 고려하여 센서에 입력되는 복사휘도를 계산한다. 센서의 물리적 특성으로 인한 복사보정의 오차를 줄이기 위해 우주방사선 및 우주먼지(space debris)로 인해 위성 운용기간 중 그 특성이 저하되는 태양광 확산기(solar Diffuser)의 특성변화를 모니터링하기 위한 DAMD(Diffuser Aging Monitoring Device)를 이용한다. 정지궤도 해양위성 주관운영기관인 한국해양연구원의 해양위성센터에서는 정지궤도 해양위성 복사보정을 수행하기 위한 S/W를 통신해양기상위성 자료처리시스템 개발사업의 일환으로 개발하였으며, 관련 성능 시험을 수행하고 있다.

• The Korean Journal of Air & Space Law and Policy
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• v.3
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• pp.233-258
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• 1991

This paper examines current developing status of space law as defined in terms of its unique principle that "the utilization of outer space for all mankind's interest". As commercialization of space activities has brought about heated debate on its legitimacy with respect to that principle, space law has come to witness a dual situation. One is the realization of that principle in establishing commercial space activities system where all mankind's interest is respected through the non-discriminatory distribution mode of space benefit. In satellite telecommunication system, the INTELSAT Organization assures its public service policy while protecting itself against a competition from separate systems. For remote sensing, commercialization of LANDSAT Systems promoted since 1984 seems not to affect present non-discriminatory distribution of data and information obtained. On the other hand, active participation of private entity aiming at commercial profit enables national government to manage more effective control and supervision of those activities with a view to promoting national interests. Also, newly developed private rules and regulations are emerging in business relations about commercial space activities. Extended capacity of national government assuring its national interest in production and distribution of international resources that is outer space, and regulation of space activities by newly developed rules and customs provoke a concern about a identity problem of space law. The best way to summarize this perspective might consist in saying that non space law regulations, which are not assumed as aiming at the promotion of all mankind's interest, are confirming their role about space related activities. For those reasous, we are now facing a developing status of space law as developments of commercial space activities continues.

• Journal of the Korean Institute of Gas
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• v.8 no.1 s.22
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• pp.30-36
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• 2004

Although the usage of gas as one of the most economical energy source is ever expanding, numerous gas accidents occur as a result of negligence in safety management. The main reason behind such accident is that the current safety control system relies heavily on the manual control mechanism. This paper designed and developed a prototype of a computerized gas safety control system that automates such critical functions as the alarm sensing and the valve control. Since the system is connected through a digital network, the control can be performed remotely. Most importantly, the accidental risk or damage can be greatly reduced since the system monitors and reacts actively to gas leakage in real time.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.29 no.6
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• pp.1403-1412
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• 2019

Effect of damage and loss cost for downtime is huge, if physical devices such as turbines, pipe, and storage tanks are in the abnormal state originated from not only aging, but also cyber attacks on the control and monitoring system like PLC (Programmable Logic Controller). To improve availability and dependability of the physical devices, we design and implement an indirect health monitoring system which sense temperature, acceleration, current, etc. indirectly, and put sensor data into Influx DB in real-time. Then, the actual performance of detecting abnormal state is shown using the indirect health monitoring system. Analyzing data are acquired using the real-time indirect health monitoring system, abnormal state and security threats can be double-monitored and lower maintenance cost utilizing prognostics and health management.

• The Transactions of the Korean Institute of Power Electronics
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• v.10 no.2
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• pp.138-147
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• 2005

This paper presents a SPMSM(Surface-mounted Permanent Magnet Synchronous Motor) servo drive system using high performance TMS320F2812 DSP for the industrial application. The DSP(Digital Signal Processor) Controller enables an enhanced real time algorithm and cost-effective design intelligent for only exclusively motor drives which can be yield enhanced operation, fewer system components, lower control system cost, increased efficiency and high performance. The suggested system contain speed and current sensing circuits, SVPWM(Space Vector Pulse Width Modulation) and I/O interface circuit. The developed servo drive control system showns a good response characteristics results and high performance features in general purposed 400[w] machine. This system can achieve cost reduction and size minimization of controllers.

• Proceedings of the KIEE Conference
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• 2006.07c
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• pp.1627-1628
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• 2006

In this paper, mesoporous only platinum electrode and micro pore platinum electrode with mesoporous Pt are fabricated and characterized on a silicon substrate to check their usability as enzymeless sensing electrodes for developing non-disposable glucose sensors integrated with silicon CMOS read out circuitry. Since most of electrochemical glucose sensors are disposable due to the use of the enzymes that are living creatures, these are limited to use in the in-vivo and continuous monitoring system applications. The proposed mesoporous Pt electrode with approximately 2.5nm in pore diameter and 150nm in height was fabricated by using a nonionic surfactant $C_{16}EO_8$ and an electroplating technique. The micro pore Pt electrode with mesoporous Pt means the mesoporous Pt electrode fabricated on top of micro pore arrayed Pt electrode with approximately $10{\mu}m$ in pore diameter and $80{\mu}m$ in height. The measured current responses at 10mM glucose solution of plane Pt, micro pore Pt, micro pore with mesoporus Pt, and mesoporous Pt electrodes are approximately $9.9nA/mm^2$, $92.4nA/mm^2$, $3320nA/mm^2$ and $44620nA/mm^2$, respectively. These data indicate that the mesoporous Pt electrode is much more sensitive than the other Pt electrodes. Thus, it is promising for non-disposable glucose sensor and electrochemical sensor applications.

• Journal of Sensor Science and Technology
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• v.5 no.5
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• pp.63-68
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• 1996

In order to implement the integrated capacitive pressure sensors, which contains integrated interface circuits to detect the electrical output signal, several main factors that have a bad effect on the characteristics of sensors must be improved, such as parasitic capacitance effects, temperature/thermal drift, and the leakage current of a readout circuitry. This paper describes the novel design of the dedicated CMOS readout circuitry that is consists of two capacitance to frequency converters and 4 bit digital logic compensating circuits. Dividing the oscillation frequency of a sensing sensor by that of reference sensor, this circuit is designed to eliminate the thermal/temperature drift and the effect of the leakage currents, and to access a digital signals to obtain a high signal-to-noise(S/N)ratio. Therefore, the resolution of this circuit can be increased by increasing the number of the digital bits. Digital compensated circuits of this circuits, except for the C-F converters, are fabricated on a FPGA chip, and fundamental performance of the circuits are evaluated.

• The KIPS Transactions:PartD
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• v.16D no.2
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• pp.177-184
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• 2009

Environmental monitoring systems are widely developed for analyzing environment and understanding an ecosystem according to the advance of wireless communication and various sensing techniques. To extract useful information, it requires high cost for processing a query, because these systems have to handle huge volume of raw sensor data which is transmitted from a wide area in environmental monitoring applications. Besides, it is also hard to answer an user defined query which requests to check current and near future condition. In this paper, we propose the monitoring system structure for processing a user defined query for environmental monitoring. It also describes the utilization of sensor data filtering and abstraction model. The designed abstraction model which is based on the slope grid in GIS supports fast data access and update. To analyze condition, the extracted data from abstraction model of each sensor type is combined in a query processor. It is useful to provide meaningful information to users.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.10a
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• pp.754-758
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• 2005

Optimization of process variables such as arc current, welding voltage and welding speed in terms of the weld characteristics desired is the key step in achieving high quality and improving performance characteristics without increasing the cost. Consequently, incorrect settings of those process variables give rise to deviations in the welding characteristics from the desired bead geometry. Therefore, trainee welders are referred to the tabulated information relating different metal types and thickness as to recommend the desired values of process variables. Basically, the bead geometry plays an important role in determining the mechanical properties of the weld. So that it is very important to select the process variables for obtaining optimal bead geometry. However, it is difficult for the traditional identification methods to provide an accurate model because the optimized welding process is non-linear and time-dependent. In this paper, the possibilities of the Infra-red sensor in sensing and control of the bead geometry in the automated welding process are presented. Infra-red sensor is a well-known method to deal with the problems with a high degree of fuzziness so that the sensor is employed to build the relationship between process variables and the quality characteristic the proposed above respectively. Based on several neural networks, the mathematical models are derived from extensive experiments with different welding parameters and complex geometrical features. The developed system enables to select the optimal welding parameters and control the desired weld dimensions during arc welding process.