• The Transactions of the Korean Institute of Electrical Engineers P
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• v.57 no.4
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• pp.356-361
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• 2008

The conventional drive system of SRM has a current sensor per each phase. The torque demand signal generated by the outer control loop is translated into individual current reference signal for each phase. The torque is controlled by regulating these currents. Using the SRM in a variable-speed control, the phase currents are generally regulated to achieve a square wave. The simplest form of current regulation uses fixed frequency delta modulation of the phase voltages. The aim of this paper is to regulate 3-phases current of SRM by only single current sensor using delta modulation with digital chip. In this paper, the asymmetric bridge converter which is able to control independently phases and be excited simultaneously is used as the driver system for 6/4 poles SRM. And the current sensor is replaced 3 sensors of each phase with only one on bus line of converter so as to detect current of every phase. The proposed delta modulation technique has been implemented in a simple digital logic circuit using EPLD(Electrically Programmable Logic Device). This method is verified through simulation and experiment results.

• The Transactions of the Korean Institute of Power Electronics
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• v.4 no.3
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• pp.231-239
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• 1999

An improved version of current-regulated delta modulator (CRDM) is investigated for the output cunent control of v voltage-source inverters that have transformer-coupled series resonant load and are operated at the resonant frequency. Conventional CRDM has not only CUlTent offset problem but also transformer flux saturation problem when i it is applied to induction heating systems that have transformel-coupled loads. To cope with these problems, the effect of flux saturation is analysed, and simple method to av이d the problem is proposed. And integral type of CRDM is a adopted to remove the cunent offset. The boundaries of integrator gain for stable operation is calculated using the c concept of sliding mode controL The validity of proposed strategy is vel퍼ed through simulations and prototype e experiments.

• The Transactions of the Korean Institute of Power Electronics
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• v.3 no.1
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• pp.36-45
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• 1998

A simple source voltage clamped resonant link (SVCRL) inverter is proposed to clamp the DC link voltage to the input source voltage and reduce the current rating of resonant inductor. The current control of a permanent magnet synchronous motor (PMSM) using a predictive current control technique (PCCT) employing the SVCRL inverter is also investigated to overcome the disadvantage of the current regulated delta modulation (CRDM) control technique. By using the PCCT based on the discrete model of a PMSM and estimation of back EMF, the minimized current ripple with small number of switchings can be obtained. Finally, the comparative computer simulation and experimental results are given to show the usefulness of the proposed technique.

• Proceedings of the KIEE Conference
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• 1996.07a
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• pp.567-570
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• 1996

A predictive current control technique for an induction motor employing a resonant DC link inverter is proposed to overcome the disadvantage of the current regulated delta modulation(CRDM) which was employed to control the resonant DC link inverter. The discrete model of an induction motor and estimation of back EMF are investigated and a novel predictive current control technique is newly developed based on this discrete model and estimated back EMF. Using the proposed control technique, the minimized current ripple with reduced offset can be obtained. The usefulness of the proposed technique is verified through the computer simulation.

• Proceedings of the Korean Biophysical Society Conference
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• 2003.06a
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• pp.47-47
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• 2003

The presenilin 1 (PS1) or PS2 is an essential component of the ${\gamma}$-secretase complex, which mediates the intramembrane proteolysis of selected type-I membrane, including the ${\beta}$-amyloid precursor protein (APP) to yield A${\beta}$. Familial Alzheimer's disease (FAD)-associated mutations in presenilins give rise to an increased production of a highly amyloidogenic A${\beta}$42. In addition to their well-documented proteolytic function, the presenilins play a role in calcium signaling. We have previously reported that presenilin FAD mutations cause highly consistent alterations in intracellular calcium signaling pathways, which include deficits in capacitative calcium entry (CCE), the refilling mechanism for depleted internal calcium stores. However, molecular basis for the presenilin-mediated modulation of CCE remains to be elucidated. In the present study, whole-cell patch clamp method was used to identify a specific calcium-permeable ion channel current(s) that is responsible for the CCE deficits associated with FAD-linked PS1 mutants. Unexpectedly, both voltage-activated and conventional store depletion-activated calcium currents I(CRAC), were absent in HEK293 cells, which were stably transfected either with wild-type or FAD mutant (L286V, M146L, and delta E9) forms of PS1. Recently, magnesium-nucleotide-regulated metal cation current, or I(MagNum), has been described and appears to share many common properties with I(CRAC) including calcium permeability and inhibitor sensitivity (e.g. 2-APB). We have detected I(MagNum) in all 293 cells tested. Interestingly, FAD mutant 293 cells developed only about half of currents compared to PS1 wild type cells.

• Biomedical Science Letters
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• v.14 no.2
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• pp.69-76
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• 2008

${\gamma}$-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system, and its actions are mediated by subtypes of GABA receptors named as $GABA_A$, $GABA_B,\;and\;GABA_C,\;GABA_A$, receptor consisting of ${\alpha},\;{\beta},\;{\gamma}\;and\;{\delta}$ subunits is a heterooligomeric ligand-gated chloride channel. This study was performed to investigate regulation of $GABA_A$ receptor by protein kinase C(PKC). Ion currents were recorded using gramicidine-perforated patch and whole cell patch clamp. mRNA encoding the subunits of PKC expressed in major pelvic ganglion (MPG) neurons was detected by using RT-PCR. The GABA-induced inward current was increased by PKC activators and decreased by PKC inhibitors, respectively. These effects were not associated with intracellular $Ca^{2+}$ and GAG (1-oleoyl-2-acetyl-sn-glycerol), a membrane permeable diacylglycerol (DAG) analogue. These results mean that the subfamily of PKC participating in activation of $GABA_A$ receptor would be an atypical PKC (aPKC). Among theses, ${\xi}$ isoform of aPKC was detected by RT-PCR. Taking together, we suggest that excitable $GABA_A$ receptor in sympathetic MPG neuron seemed to be regulated by aPKC, particular in ${\xi}$ isoform. The regulatory roles of PKC on excitatory $GABA_A$ receptors in sympathetic neurons of MPG may be an important factor to control the functional activity of various pelvic organs such as bowel movement, micturition and erection.