• Journal of the korean academy of Pediatric Dentistry
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• v.26 no.1
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• pp.146-150
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• 1999

With the improved cure rates for childhood malignant conditions in the past decade, late effects of cancer therapy must be recognized to minimize their impact on the quality of life in long-term survivors. Chemoradiation therapy is a major part of pediatric oncology treatment and is implicated in causing tooth agenesis, microdontia, root shortening, early apical closure, and coronal hypocalcification. Dental development may be affected by illness, trauma, chemotherapy, or radiation therapy at any point prior to complete maturation. Treatment given during the first 3.5 years of life was more likely to affect the dental lamina and crown formation and result in a small tooth. Dental treatment affected by chemoradiation damage to developing teeth includes orthodontic tooth movement, prosthetic abutment consideration, periodontal health, space maintenance, requirement for home fluoride regimens to protect hypomineralized teeth, and enodontic procedures. Dental abnormalities are common in patients treated for cancer, and these children require aggressive dental follow-up. Meticulous surveillance may facilitate detection of abnormalities, enabling the dental practitioner to intervene earlier in promoting a more aggressive regimen of oral care, thus reducing the morbidity associated with dental sequelae of oncotherapy, specifically periodontal disease and malocclusion. In this case, we report microdontia of all permanent second premolar and second molar in an 8 year old boy treated with chemotherapeutic agents during period of active dental development(14 months to 38 months of age).

• Tuberculosis and Respiratory Diseases
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• v.80 no.1
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• pp.69-76
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• 2017

Background: Much of the attention of tuberculosis (TB) programs is focused on outcomes of microbiological cure and mortality, and health related quality of life (HRQL) is undervalued. Also, TB patients have a significantly higher risk of developing depression and anxiety compared with those in the general population. We intend to evaluate the HRQL and the prevalence of symptoms of depression and anxiety in hospitalized patients with TB. Methods: Cross-sectional study in a tertiary care hospital in Brazil. Adult patients with pulmonary TB that were hospitalized during the study period were identified and invited to participate. HRQL was measured using the Medical Outcomes Study Short Form-36 (SF-36) version 2. Hospital Anxiety and Depression Scale (HADS) was used to record symptoms of anxiety and depression. Results: Eighty-six patients were included in the analysis. The mean age of all patients was $44.6{\pm}15.4$ years, 69.8% were male, and 53.5% were white. Thirty-two patients (37.2%) were human immunodeficiency virus positive. Twenty-seven patients (31.4%) met study criteria for depression (HADS depression score ${\geq}11$) and 33 (38.4%) had anxiety (HADS anxiety score ${\geq}11$). Scores on all domains of SF-36 were significantly lower than the Brazilian norm scores (p<0.001). Conclusion: The present study shows that TB patients may have a poor HRQL. Additionally, we found a possible high prevalence of depression and anxiety in this population. Health care workers should be aware of these psychological disorders to enable a better management of these patients. The treatment of these comorbidities may be associated with better TB outcomes.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.18 no.2
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• pp.122-132
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• 2008

The purpose of this study is to present the basic materials of a developmental counterplan by assessing prevalence of musculoskeletal symptoms and characteristics of work-related ergonomic risk factors. The prevalence of musculoskeletal symptoms of 64 vineyard workers was investigated by using a self-reported questionnaire. And the vineyard workers' tasks were also collected and analyzed during 9-month period by observing and videotaping methods to identify the ergonomic risk factors. The prevalence rate of musculoskeletal symptoms of female(84.4%) was much higher than that of male(62.5%) and a total prevalence rate was 73.4%. There was no different prevalence of musculoskeletal symptoms between age over 60 years and under 60 years. The prevalence rates of musculoskeletal complaints for each body part were 48.4%, 42.2%, and 35.9% for the wrist, legs/knee, and shoulder, respectively. In postural risk analysis, 7 works(REBA score) represented the high risk tasks such as delivering harvest boxed(12), picking cluster(11) and so on. The main works(exposure score) were orderly ranked as picking cluster(1590), pruning branch(388), and cluster thinning(327). The risk factors of vineyard work were identified as follows: shoulder flexion(${\geq}45^{\circ}$), wrist Flex./Ext.(${\geq}15^{\circ}$), hand force(power/pinch-grip), and prolonged standing(${\geq}4hr$). The engineering solutions including an improvement of hand tools, working process, and working environment should be applied to the high risky tasks in order to resolve the ergonomic problems. The administrative solutions such as improving a distribution of resting time, an exercise cure, an early recognition of symptoms and rehabilitation might be another solution for reducing musculoskeletal symptoms in vineyard workers.

• Journal of Oriental Neuropsychiatry
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• v.19 no.3
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• pp.195-203
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• 2008

Objective: 'GyoGam-Dan' is known as a medicine to cure depression in Donguibogam (traditional Korean oriental medicine book). GyoGam-dan which is composed of Cyperi Rhizoma L. and Poria cum Radix pini has been used by basic prescription of asymptom related to all kinds of Qi(氣) disease. Although it has been clinically used for a long time, its safety have never been proved till now. Methods: We had collected data of 610 cases of patients taking 'GyoGam-Dan' at Wonkwang univ. oriental medical center for a period of three years (2005.3.09-2008.04.30). On the patients' blood, the levels of LFT and RFT were examined and the residual levels of heavy metals and pesticides were measured. Results: There were 610 patients who had taken GyoGam-Dan for about three years. In the patients, the most common diseases is depression, followed by palpitation, and then insomnia. Among the patients' estimations on its effectiveness, there were many of positive ones. The blood analyses of patients who had taken GyoGam-Dan did not show any problems and moreover there was not any problems in the levels of residual heavy metals and agricultural pesticides. Taken together, GyoGam-Dan was proved to be a safe medicine for health. Conclusions: Our clinical and chemical studies show that GyoGam-dan has the anti-stress effect and is a safe medicine of which side effect does not exist. Hereafter, Nigorous clinical trial on GyoGam-dan is required.

• Journal of Chest Surgery
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• v.9 no.1
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• pp.98-101
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• 1976

Clinical observations were made on a total 104 cases of spontaneous pneumothorax during the period of 5 years from MAR. 1971 to MAR. 1976 at the Dept. of Chest Surgery, Korea University Medical College. The ratio of male to female cases was 7.4 : 1 in male predominance, and age distribution was 73% of the total cases within the 15-40 age range. There were 56 patients (53.8%) of right sided pneumothorax and 44 patients (42.3%) of left sided pneumothorax, 8 patients presented bilateral spontaneous pneumothorax. The etiologic factors were tuberculous origin in 42.3%, rupture of bullae or blebs in 15.4%, acute pulmonary infection in 3.8%, pulmonary paragonimiasis in 2.9%, cysticercosis 1%, Marfan's syndrome in 1.9%, unknown causes in 32.7%. In all 104 cases, closed chest tube thoracostomy were performed for reexpansion of collapsed lung. In 50 cases of 104 cases, intrapleural instillation of Quinacrine HCl (Atabrine, Winthrop Laboratories, New York, N.Y.) thru the chest tube was used to control of recurrent pneumothorax, and compared observation with 54 cases control group of closed chest tube thoracostomy only. In both groups, 1) cure rates were 63% in control group and 88% in Atabrine group. 2) average duration of inserted chest tube were 5.6 days in control group and 5.7 days in Atabrine group.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.16 no.2
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• pp.28-33
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• 2010

Purpose : The purpose of this study is to find out the effects of Joint and Muscle Mobilization applied to the patients with Degenerative Disc Disease by measuring, assessing and analyzing the changes on pain and in flexibility before and after Joint and Muscle Mobilization. Method: Surveyed from June. 2008 to July. 2009 were 10 patients suffering from DDD. Joint and muscle Mobilization were applied for 15 minutes in total. After Joint Mobilization, the Oswestry Disability Index(ODI), Visual Analogue Scale (VAS) were used to measure the degree of the pain on the patients. After Joint and Muscle Mobilization, Spinal-$Mouse^{(R)}$ were used to measure the degree of the flexibility on the patients. Result: 1. There was significant decrease in the numerical values of the VAS & ODI after Joint and Muscle Mobilization (p<0.01). 2. There was significant decrease in the degree of the pain on the patients after Joint and Muscle Mobilization (p<0.01). 3. From the analysis into DDD in the degree the pain before and after Joint and Muscle Mobilization with Paired Sample T-test, It became evident that the longer the period of treatment was, the higher the pains decreases drastically, while significant difference was shown in the flexibility and the degree of the pain (p<0.01). Conclusion: Summed up, it can be generally concluded that Joint and Muscle Mobilization is an effective treatment to rid the patients with DDD of pains safely and promptly. It is, therefore, suggested to continue and expand the study on the cure of DDD and to motivate patients. Joint and Muscle Mobilization is considered as safest and most efficient pain remedy.

• Journal of Korean Medical classics
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• v.25 no.2
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• pp.25-41
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• 2012

Objective : Neijingshiyifanglun with additions and emendations was written by Liu Yude, a doctor who lived during Ming period. I researched the origin of the book, and analyzed the features of it as well. I also approximated his birth date and death date. In doing this, I gained a better understanding the practice of medicine in ancient China. Method : I researched the book by comparing its contents, including the causes of diseases, the descriptions of symptoms, the transmissions of diseases, and treatments, with other sources that he had referenced. Result : In understanding Hwangdineijing, Liu Yude was influenced by many medical scholars such as, Wang Bing, Ma Shi, and Wu Kun, but his opinion is most similar to that of Zhang Jiebin. In the field of the Chinese Medical Theory, he was deeply influenced by 'JinYuan-Sidaijia's theories, particularly Li Gao and Zhu Zhenheng. In fanglun, he was greatly influenced by Yifangkao. He concluded that 'aggregationaccumulation' was a disease of stuffiness, and suggested its cure in through 'yangjingzezichu' and 'treatment of blood aspect'. He recognized the disease of 'reversal of qi' as the disease of 'jiaoqi'. He also indicated that the word of 'qi' is not 'rough' but 'tears' or 'yingfengliulei'. Conclusion : 1. He was an excellent medical practitioner and scholar in the history of oriental medicine. 2. He found and corrected errors in the opinions of Wang Bing, Ma Shi, and Wu Kun. 3. He frequently practiced Taipinghuiminhejijufang, and considered Spleen-Stomach, yin-blood, and fire-heat important. 4. He captured the spirit of Huangdisuwenxuanminglunfang, Neijingshiyifanglun, Yifangkao in views of remedy and theory. 5. Neijingshiyifanglun with additions and emendations is the most comprehensive book about fanglun because of its thorough analysis of the Hwangdineijing and its connection to the treatment of ancient diseases in Oriental Medical History.

• Journal of Korean Physical Therapy Science
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• v.8 no.2
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• pp.989-995
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• 2001

The purpose of this paper was to enable patients, who suffer from muscle damage. to return to their normal activities as soon as possible. With this in mind. this experiment was carried out to make an analysis of a variety of ingredients subjected to changes when muscle damage or muscle soreness was treated with aceclofenac, NSAID, and to find out what effect the anti-inflammation produced in relation to such symptoms. It made use of male rats (Sprague-Dawely) as subjects. It carried out two kinds of experiments: one was a preliminary experiment from March 15, 2001 to March 20, 2001 and the other was a main experiment from March 30, 2001 to April 15, 2001. Each group was composed of five rats. In case of DOMS. it worked with eight male adults from April 20. 2001 to April 30, 2001. It have come up with the following conclusions: 1. The leucocytes and erythrocytes of the experiment group were decreasing with the lapse of time in comparison with those of the contrast group. And a decrease in the number of hemoglobin had remarkably statistic significance (P<0.05). 2. Neutrophil, Lymphocyte and Monocyte decreased in 36, 24, 12 and 24 hours, respectively, which means that they had a significant difference(P<0.05). 3. CPK and LDH were reduced remarkably through the whole time slot in comparison with the contrast group, and had statistic significance(P<0.05). The findings above show that anti-inflammations cure bruises or damage or myalgia in a shorter period of time than the normal recovery of other treatment.

• Journal of Acupuncture Research
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• v.21 no.5
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• pp.249-256
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• 2004

Objectives : Wilson's disease is an autosomal recessive abnormality in the hepatic excretion of copper that results in toxic accumulation of the metal in liver, brain, and other organs. The purpose of this case study is to show a case with Wilson's disease treated with acupuncture therapy. Methods : We experienced a 17 year old male patient with a Wilson's disease whose main symptoms are neurological symptoms, such as spasticity, quadripleia and dysphagia. The patient was treated with acupuncture therapy for 3 weeks. Results : Spasticity was assessed by the modified Ashworth scale in an every week. 1. Lt. elbow, wrist and ankle joint improved Gr.III to Gr.II. 2. Rt. each joints and Lt. knee joint seemed to improve a little but no grade changed. Conclusions : This study is just one case and the period of acupuncture therapy is short, which make this case study less sufficient to decide the effect of acupuncture therapy. However, in this case study, acupuncture therapy seems somewhat effective to neurological symptoms of Wilson's disease, such as spasticity and quadriplegia. We suggest that oriental medicine should be studied to cure Wilson's disease from now on.

• The Journal of Korean Medical History
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• v.29 no.2
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• pp.49-59
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• 2016

Ginseng, a Korean native herb, has been a symbol of mystic cure-all which provides longevity benefits throughout Korean history. According to Chinese historical records, a major source of wild ginseng has been described as Korean peninsula, which is the most suitable ginseng production area, and the Manchu region near Mt. Baekdu and the Maritime Province. Since Tang dynasty period (618-917 CE), Chinese has also called ginseng as "Goryeo Ginseng", which is named after "Goguryeo" (37 BCE-668 CE), an ancient kingdom of Korea, from which they mainly imported the herb as the region was famous for its high quality of ginseng. To date, it refers to Korean ginseng. This study compares the medicinal properties of ginseng as stated in the ancient Korean medical books with the major Korean historical records regarding the usage of ginseng and its symbolism of longevity in everyday life. By contrasting these findings, we tried to figure out how the actual medicinal properties of ginseng and the anticipation of longevity are related. It was confirmed that the expectations about longevity were widely applied to everyday life. In addition, the study investigates the various usage of ginseng as a motive for decorative patterns and as an ingredient for daily products including snacks, health drinks, various types of food, clothing patterns, and so on. Finally, the usage of ginseng ingredients in the cosmetic products fulfilled the desire of Korean people to purchase, showing the aesthetic recognition and medicinal understandings about the herb. These findings suggest that ginseng is an important medicinal agent that not only symbolizes longevity and good health but also has a great influence on the lives of Koreans.