• Title/Summary/Keyword: cure conditions

Search Result 158, Processing Time 0.029 seconds

Effect of Chamomile German Oil Application of IgG1 and IgE 1 to Atopic Dermatitis in NC/Nga Mice Model (Chamomile German 오일도포가 아토피성 피부염을 가진 NC/Nga 생쥐모델의 혈청 IgE와 IgG1양 변동에 미치는 영향)

  • Shin, Gil-Ran;Kim, Yang-Weon
    • Korean Journal of Human Ecology
    • /
    • v.18 no.2
    • /
    • pp.501-507
    • /
    • 2009
  • Atopic dermatitis is one of the most common skin disease in children and a characteristic chronically recurrent form of dermatitis with a hereditary tendency, affecting infants and may extend to the childhood or th the adult age. Environmental factors, stress, and foodstuffs such as milk, egg may cause atopic dermatitis. Nc/Nga mice were used as an animal model for human atopic dermatitis. The divided by 4group such as normal group, BMAC group, FK506 group, MR group for this study raised in conventional conditions. To investigate effect of Chamomile German on atopic dermatitis in NC/Nga mice, the serum IgE and IgG1 level were measured while the severity degree of the skin lesion was examined by the naked eyes of two volunteers who were unaware of the treatment status. The results were the followings. 1. The score on the severity degree of skin dermatitis in FK 506 and MR group was lower than that in control group. 2. The serum IgE level in control group was higher 25% than that in normal group. 3. The serum level of IgE in FK506 and MR group compares to control group was decreased. 4. The serum IgG1 level was decreased more than 3.5 times in FK506 compared to control group while MR group had significantly less the serum IgG1 than control group. From the above results, treatment of Chamomile German oil had the effect on atopic dermatitis in NC/Nga mice. If scientific researches on aroma oil are performed in various way, aroma oil will be used to cure skin dermatitis as a alternative therapy in the future.

A Clinical Report of Insomnia due to deficiency of Yang (양허(陽虛) 불면증(不眠症)환자 치험 1례)

  • Kim, Su-Youn;Kim, Eun-Jung;Lee, Dong-Won;Kim, Kyung-Hwa
    • Journal of Oriental Neuropsychiatry
    • /
    • v.15 no.1
    • /
    • pp.121-126
    • /
    • 2004
  • The Common Symptoms of insomnia are to be hard to sleep, often wake up at night, be easy not to fall asleep again after waking up. In serious conditions, an insomniac can never get to sleep overnight. This is the case that we diagnosed a 49-year-old patient who demonstrates insomnia, palpitation, anxiety, dizziness, distress in the stormach as Deficiency of Yang(陽虛) and treated her. At 1st stage we diagnosed the patient as Insufficiency of both the heart and the spleen(心脾兩虛) and prescribed Gwibi-tang(歸脾湯), and next stage we dispensed bogol-dan(補骨丹) to cure Deficiency of Kidney Yang. As the result of treatment, the patient made a good improvement. We considered that this case report to be a good prcedent of Insomia due to deficiency of Yang.

  • PDF

Design Analysis/Manufacturing /Performance Evaluation of Curved Unsymmetrical Piezoelectric Composite Actuator LIPCA (곡면형 비대칭 압전복합재료 작동기 LIPCA의 설계해석/제작/성능평가)

  • Gu, Nam-Seo;Sin, Seok-Jun;Park, Hun-Cheol;Yun, Gwang-Jun
    • Transactions of the Korean Society of Mechanical Engineers A
    • /
    • v.25 no.10
    • /
    • pp.1514-1519
    • /
    • 2001
  • This paper is concerned with design, manufacturing and performance test of LIPCA ( Lightweight Piezo- composite Curved Actuator) using a top carbon fiber composite layer with near -zero CTE(coefficient of thermal expansion), a middle PZT ceramic wafer and a bottom glass/epoxy layer with high CTE. The main point of this design is to replace the heavy metal layers of THUNDER by thigh tweight fiber reinforced plastic layers without losing capabilities to generate high force and large displacement. It is possible to save weight up to about 30% if we replace the metallic backing material by the light fiber composite layer. We can also have design flexibility by selecting the fiber direction and the size of prepreg layers. In addition to the lightweight advantage and design flexibility, the proposed device can be manufactured without adhesive layers when we use epoxy resin prepreg system. Glass/epoxy prepregs, a ceramic wafer with electrode surfaces, and a graphite/epoxy prepreg were simply stacked and cured at an elevated temperature (177 $^{circ}C$ after following an autoclave bagging process. It was found that the manufactured composite laminate device had a sufficient curvature after detached from a flat mold. The analysis method of the cure curvature of LIPCA using the classical lamination theory is presented. The predicted curvatures are fairly in agreement with the experimental ones. In order to investigate the merits of LIPCA, a performance test of both LIPCA and THUNDE$^{TM}$ were conducted under the same boundary conditions. From the experimental actuation tests, it was observed that the developed actuator could generate larger actuation displacement than THUNDERT$^{TM}$.

Soap-Free Emulsion Polymerization of Styrene/Butadiene/Acrylonitrile System (Styrene/Butadiene/Acrylonitrile계 무유화제 유화중합)

  • Chung, Huey-Sil;Shin, Young-Jo
    • Applied Chemistry for Engineering
    • /
    • v.4 no.2
    • /
    • pp.284-290
    • /
    • 1993
  • The soap-free emulsion polymerization was carried out for Styrene/Butadiene system with Acrylonitrile as hydrophilic comonomer and KPS as initiator. Under the condition of below 50% conversion, the dependence of Rp on $[AN]^n$ and $[KPS]^n$ was found to be n=1.617-1.050 and n=0.83-0.96 for [AN] and [KPS], respectively. The effect of $[AN]^n$ and $[KPS]^n$ on particle number density (Np) was determined to be n=1.533 and n=0.733, respectively. The highest conversion was obtained under the conditions of pH=5 and ratio of total monomer (g) to water (g)=0.5. The mechanical properties of SBR obtained in this experiment were shown to be inferior to commercial SBR in terms of tensile strength, 300% modulus and elongation. It was found that cure rate of SBR prepared in this experiment was faster than that of commercial SBR.

  • PDF

Chronic Wound Treatment Using rh PDGF (재조합 인체 혈소판 성장인자(rh PDGF)를 이용한 만성 창상의 치료)

  • Jeong, Wong-Ki;Lew, Dae-Hyun;Park, Beyoung-Yun
    • Archives of Reconstructive Microsurgery
    • /
    • v.11 no.2
    • /
    • pp.173-178
    • /
    • 2002
  • Wound healing is the result of interaction of normal cellular and biochemical responses that restore the interrupted anatomical structure in limited period. When any response of them is impaired, it results in chronic wound. The factors that influence the wound healing process is not only limited to the fundamental disease of the individual but also the local factors, especially various growth factors secreted from the various cells involved in tissue regeneration have important role. Recent reports that the chronic wounds are depleted of these growth factors have led active studies on the alteration of local wound environment with manipulation of the growth factors and the its application in management of chronic wounds. We investigated the effect on the chronic wounds in 10 patients with various pathologic conditions to suggest the appropriate application and guideline of the indication. The chronic wounds resulting from various causes in 10 patients were treated with rhPDGF gel and good wound care. All the chronic wounds were located on the lower extremity and the average diameter was 2.5 cm. 7 patients were completely cured within 8 weeks, however the patient who received previous radiation therapy the healing was delayed to 14 weeks. Two patients with vascular ulcer were not cured with rhPDGF alone. Local application of rhPDGF has yielded complete cure of the chronic wound in 70% of the patients within 2 months. The author suggests that it would be an effective alternative treatment modality of chronic wound when it is applied with good wound care and appropriate indication.

  • PDF

C-arm Guided Surgical Excision of Heterotopic Calcification (방사선 영상장치 모니터링하 이소성 석회화 절제술)

  • Choi, Hwan-Jun;Choi, Yim-Don;Park, Nae-Kyeong;Kim, Yong-Bae
    • Archives of Plastic Surgery
    • /
    • v.38 no.2
    • /
    • pp.194-198
    • /
    • 2011
  • Purpose: Heterotopic calcification is the abnormal deposition of calcium salts in tissues other than bone and enamel, and it occurs in the form of dystrophic calcification or metastatic calcification. This deposition can occur under many conditions, but in some rare cases, it may develop in burns and nonhealed scars. It is difficult to treat the combination of heterotopic calcification and ulceration in scar tissues by using conservative therapy and to determine the margin of excision in such cases. Our study proposes the use of intraoperative C-arm-guided mapping of lesions with heterotopic calcification, and adequate excision of ulcers in chronic scars where heterotopic calcification is also observed. Methods: This study included 2 patients and was conducted from January 2010 to July 2010. The first patient was a 63-year-old woman who presented with atypical calcium deposits and chronic ulceration in the lower one-third region of the right leg. The second patient was a 38-year-old man who presented with a nonhealing ulcer that had developed on the right leg 3 months earlier he had a history of 40% scalding burns on the entire body. Surgery is the most reliable method for treating heterotopic calcification therefore, both patients were treated using intraoperative C-arm-guided marginal mapping of heterotopic calcification, followed by release of contracture, and eventually split-thickness skin grafting. Results: Plain radiographs of the leg showed spotty radiopaque areas in the hard part of the scar well superficial to the underlying bones. Histopathological analysis revealed multiple foci of calcified deposits, increased fibrosis, and inflammation in the scar tissue. Surgery-related complications were not observed. Conclusion: C-arm guided excision of calcified scars and the release of contracture can cure nonhealing ulcers and may therefore prevent recalcification.

A Study on the Preventive Measures against Local Vibrations of Ships' Deck Panels (선체갑판(船體甲板)의 국부진동(局部振動)에 대한 방진설계(防振設計)에 관한 연구(硏究))

  • K.C.,Kim;H.M.,Kim
    • Bulletin of the Society of Naval Architects of Korea
    • /
    • v.18 no.1
    • /
    • pp.1-8
    • /
    • 1981
  • To contribute to the preventive measures against local vibrations of ship's deck panels, some investigations into the prediction method of the natural frequency of the vibration of stiffened plates were done. Firstly, an analytical method based on the orthotropic plate analogy and the Rayleigh method using eigenfunctions of the Euler beam was shown, and numerical results of a regularly stiffened plate were compared with experimental results. And then, the method was extended to stiffened plates having one or two irregular stiffeners to obtain an approximate formula showing the relation between the change of the natural frequency and the size of the irregular stiffeners. The latter case was investigated for the purpose of providing a convenient design manual applicable to cure of local resonant vibrations of ships' deck panels by additional reinforcement of one or two stiffeners. In the analytical development the boundary was assumed to be rigidly supported and elastically restrained against rotation. In the experiment, however, only an extreme case i.e. simply supported boundary was investigated. The results of the investigation show that there is a fairly good conformity between the analytical results and the experimental ones in the first case, and that the approximate formula for the second case is confirmed also to be reliable for the design purpose. Considering that actual boundary conditions of deck panels in ship structures lie mostly somewhere between the simple support and the fixed, the authors discussed problems of the joint efficiency at the boundary of deck panels from the viewpoint of the practical application of the formulae.

  • PDF

Presumption of low hack pain and symptoms for surgical treatment (요통의 예후와 수술적응증 판단)

  • Lee, Geon-mok
    • Journal of Acupuncture Research
    • /
    • v.18 no.2
    • /
    • pp.237-244
    • /
    • 2001
  • Back pain has plagued humans for many thousands of years. The treatment of back pain is divided into operative treatment and conservative treatment. It is reported that cure rate of conservative treatment is 80~90 percent. Generally, the treatment of oriental medicine is mostly conservative treatment. But, surgery should not be used as a last resort in treatment; it is just one of many treatment options for various spinal conditions. In some instance, it can be to preferred choice; in other situations, alternative therapies may be superior. Selections of the operation in HIVD 1. Acute disc herniations with a protracted significant component af back pain. 2. Chronic disc degeneration with significant back pain and degeneration limited to one or two disc levels. 3. Sugical instability created during decompression. 4. The presence of neural arch defects coincident with disc disease. 5. Symptamatic and radiographically demonstrable segmental instability. Selections of the operation in stenosis 1. If it does not slowly progress in physical therapy and other nonoperative measures, many of these patients may ultimately need surgical decompression. 2. Absolute stenosis in an impression of CT, MRI.(under 10mm) 3. In patients with established symptoms of .neurogenic claudication. 4. In patients with bad influence of neurogenic derangement.(strength, sensory) Selections of the operation in spondylolisthesis 1. Persistence or recurrence of major symptoms for at least one year despite activity modification and physical therapy. 2. Tight hamstrings, persistently abnormal gait, or postural deformities unrelieved by physical therapy. 3. Sciatic scoliosis. 4. Progressive neurologic deficit. 5. Progressive slipping beyond 25 or 50 percent, even when asymptomatic. 6. A high slip angle (40 to 50 degrees) in a growing child, since it is likely to be associated with further progression and deformity. 7. Psychologic problems attributed to shortness of trunk, abnormal gait, and postural deformities characteristic of more severe slips.

  • PDF

Bonding of the silane containing multi-mode universal adhesive for lithium disilicate ceramics

  • Lee, Hyun-Young;Han, Geum-Jun;Chang, Juhea;Son, Ho-Hyun
    • Restorative Dentistry and Endodontics
    • /
    • v.42 no.2
    • /
    • pp.95-104
    • /
    • 2017
  • Objectives: This study evaluated the influence of a multi-mode universal adhesive (MUA) containing silane (Single Bond Universal, 3M EPSE) on the bonding of resin cement to lithium disilicate. Materials and Methods: Thirty IPS e.max CAD specimens (Ivoclar Vivadent) were fabricated. The surfaces were treated as follows: Group A, adhesive that did not contain silane (ANS, Porcelain Bonding Resin, Bisco); Group B, silane (S) and ANS; Group C, hydrofluoric acid (HF), S, and ANS; Group D, MUA; Group E, HF and MUA. Dual-cure resin cement (NX3, Kerr) was applied and composite resin cylinders of 0.8 mm in diameter were placed on it before light polymerization. Bonded specimens were stored in water for 24 hours or underwent a 10,000 thermocycling process prior to microshear bond strength testing. The data were analyzed using multivariate analysis of variance (p < 0.05). Results: Bond strength varied significantly among the groups (p < 0.05), except for Groups A and D. Group C showed the highest initial bond strength ($27.1{\pm}6.9MPa$), followed by Group E, Group B, Group D, and Group A. Thermocycling significantly reduced bond strength in Groups B, C, and E (p < 0.05). Bond strength in Group C was the highest regardless of the storage conditions (p < 0.05). Conclusions: Surface treatment of lithium disilicate using HF and silane increased the bond strength of resin cement. However, after thermocycling, the silane in MUA did not help achieve durable bond strength between lithium disilicate and resin cement, even when HF was applied.

Effect of Different Types of Bonding Agent and Application Methods on Shear Bond Strength of Orthodontic Bracket (Bonding agent의 종류 및 적용 방법에 따른 교정용 브라켓의 전단결합강도에 관한 연구)

  • Lee, Jaehee;Kim, Jongsoo
    • Journal of the korean academy of Pediatric Dentistry
    • /
    • v.44 no.4
    • /
    • pp.419-426
    • /
    • 2017
  • Attachment of the orthodontic bracket conducted during the window opening procedure can result in failure due to various adverse conditions such as blood or saliva contamination, or other wet conditions. For the success of the bracket attachment, reduction of total operation time is crucial. The purpose of this literature is to evaluate the differences between the final resultant shear bond strength of the conventional method of using phosphoric acid and self-etching primer, and that of the operation time-reduced method in which the curing step is omitted subsequent to the primer application. A total of 40 human maxillary incisors were prepared. Group I(control group) and II were etched with 37% phosphoric acid and Group III and IV were conditioned with self-etching primer. Attachment of the group I and III was conducted by manufacturer's instructions. The operation time of Group II and IV was reduced by eliminating the curing step after the primer application. The resultant shear bond strength of each group was measured and an adhesive remnant index (ARI) was recorded. The mean shear bond strength of group I, II, III, and IV were 14.16 MPa, 8.33 MPa, 8.29 MPa, and 6.48 MPa respectively. Significant differences could only be found between the control group and the experimental groups (p < 0.05). The ARI indicated no significant difference among all groups.