• Korean Journal of Pharmacognosy
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• v.25 no.3
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• pp.221-225
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• 1994

Pharmacological activities of two sesquiterpenes, curzerenone(I), and curcumenol(II) isolated from the rhizomes of Curcuma zedoaria being used as an aromatic stomachic in Chinese medicines were evaluated in rats and mice. Curzerenone (I), at 100mg/kg, p.o. showed a potent protective effect against HCl-ethanol induced gastric lesion in rats, and curcumenol(II), at the same dose level showed a CNS depressant action characterized by a potentiation of hexobarbital(HB)-induced narcosis. Both compounds showed a moderate analgesic action but did not exhibit a hypothermic action even at 200mg/kg dose level.

• Natural Product Sciences
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• v.13 no.3
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• pp.175-179
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• 2007

Phytochemical study on the rhizomes of Curcuma aeruginosa has yielded three sesquiterpenes, which were identified as zedoarol (1), curcumenol (2) and isocurcumenol (3). The structures of the compounds were determined by Infrared Spectroscopy (IR), Nuclear Magnetic Resonance (1D and 2D NMR) and Mass Spectroscopy (MS). The crude extracts and pure compounds obtained were tested against pathogenic microbes and cancer cell lines