• Journal of Nutrition and Health
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• 제28권9호
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• pp.846-854
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• 1995

Taurine concentrations in blood and various tissues were measured in cats fed normal trurine diet(0.15% taurine) and trurine-free diet(0% taurine) for 5 weeks and 12 weeks, respectively. Cumulative body weight gain in young cats fed normal taurine diet and taurine-free diet for the initial 5 weeks were 463$\pm$43g and 383$\pm$53g respectively. Taurine concentration was one to two orders magnitude higher in most tissues than in plasma, among which the liver taurine-free diet for 12 weeks resulted in 98% reduction in plasma taurine concentration, 93% reduction in whole blood tarurine concentration, and 40~90% reduction in tissue taurine concentrations compared to the values for normal taurine diet group. Among the tissues tested, taurine depletion was most profound in heart and kidney, while liver and intestine were relatively resistant to taurine depletion. Whole blood taruined concentration appeared to be a better index for the body taurine status of cats as in more closely reflects the rate of taurine depletion in tissues. Taurine depletion in cats significantly increased the concentrations of essential and non-essential free amino acids in liver, while free amino acid concentrations in other tissues were not affected by taurine depletion.

• Environmental Engineering Research
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• 제23권2호
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• pp.150-158
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• 2018

The deteriorating role of Nakdong River due to the Four Major Rivers Project has caused a series of problems, including water pollution, drying streams, aggravation of the hydroecology. Geumho River and Gyeongseong-cheon had a higher concentration index and is believed to impact the water quality of the main stream. The influence index of Geumho River and Nam River between 2015 and 2016, which have a large amount of discharge, was the highest among the tributaries in terms of the load material balance. Showing the highest average concentration and average load in the index assessment, Geumho River is believed to require an intensive management for improving the water quality of the main stream. Furthermore, when the cumulative percentage of the average concentration and average load was compared based on the water quality improvement of the tributaries mixed to Nakdong River, which was set to 60%, Geumho River, Nam River, Topyeong-cheon, and Cha-cheon, which showed the highest ratio in that order, were determined to require a water quality management program as a priority.

• Journal of Pharmaceutical Investigation
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• 제9권3호
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• pp.1-8
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• 1979

The main route of metabolism of isonicotinic acid hydrazid (INH) in man is its conjugation with acetyl coenzyme A to form acetyl-INH. The reaction is catalyzed by an N-acetyl transferase in the liver. The acetylated drug can be excreted by the kidney more efficiently than INH, and the biological half-life of the drug in the body depends upon how rapidly the drug can be acetylated. This report measured the concentration of INH in the blood of 147 individuals 6 hours after they received a standard dose (9.8mg/kg) and plotted the data as a frequeney distribution hiotogram. There was bimodality, with a mean for one subpopulation at approximately $0.6{\sim}0.8\;mcg/ml.$, and a mean for the other subpopulation between 2.8 and 4.0mcg/ml. As might be expected slow acetylators of INH are more likely to develop a cumulative toxicity to the drug. The principle ,toxicity to INH is a peripheral neuritis but this adverse effect can be prevented by given extra pyridoxin to the patients, and the vitamin does not alter the antitubercular activity of INH. This report carried out that pyridoxine does not alter the ratio of free INH to the total INH in blood.

• 한국식품과학회지
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• 제18권2호
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• pp.168-172
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• 1986

본 연구는 홍미삼으로부터 홍삼엑기스를 제조할 때 추출용매와 온도 그리고 추출시간의 변화가 추출과정중 원료삼의 팽윤성과 흡수성 그리고 홍삼엑기스의 고형분 수율의 차이를 비교한뒤 이들의 관계를 통계적으로 분석함으로서 추출조건에 따른 이들 성질을 예측코져 하였다. 홍미삼의 팽윤율과 흡수율은 에탄올의 농도가 높을수록 현저히 감소되었으며, 온도의 상승으로 흡수율은 증가되었으나 평형시의 팽윤율에는 영향을 주지않았다. 한편 가용성 물질이 용출율은 에탄올의 농도가 높을수록 감소되어었으며 온도상승에서는 반대로 증가되었다. 또한 각 추출조건에서 추출시간에 따른 팽윤율과 흡수율 그리고 용출율은 높은 상관관계를 갖는 대수함수적 관계를 가지고 있었다. 따라서 이들의 관계식으로부터 주어진 에탄올의 농도와 추출시간에서의 이들의 성질을 예측할 수 있었다.

• 한국초지조사료학회지
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• 제20권2호
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• pp.77-84
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• 2000

Eight-week old perennial ryegrass (Lolium perenne L. cv. Reveille) plants were exposed to different NO3-concentrations or osmotic stress with NaCI. Previously labeled "N was chased during 14 days of non-labeled'NO3 feeding in order to investigate NO3 metabolism in relation to osmoregulation. The short termmeasurement of osmotic potential showed that the extemal concentration of Nos- had not great effect on theosmotic potential, but that osmotic adjustment was observed in NaCl-treated plants. Total uptake of NO 3 - waslargely increased by increasing supply level of NO3 while it was depressed by exposing to osmotic stress.Nitrate reduction increased to more than 29% by increasing extemal NO,- concentration from 1 mM to 10mM. When osmotically stressed with NaCI, nitrate reduction was depressed to about 37% as compared to thecontrol. The decrease in translocation of reduced N into leaves was also observed in NaCl exposed plants. Inthe medium exposed to 10 mM NO,., osmotic contribution of nitrate to cumulative osmotic potential wasdecreased, and it was osmotically compensated with soluble carbohydrate. When osmotically stressed withNaC1, the contribution of chloride was much higher than that of nitrate. The present data indicate that N03-in plant tissues, factually affected by the assimilation of this ion, plays an active role in osmotic regulation incorrelation with other osmotica such carbohydrate and chloride.(Key words : Nitrate metabolism, Osmotic stress, Nitrate supply level, Osmoregulation)ate supply level, Osmoregulation)

• Earthquakes and Structures
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• 제11권4호
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• pp.649-664
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• 2016

A seismic damaged bridge may be hit again by a strong aftershock or another earthquake in a short interval before the repair work has been done. However, discussions about the impact of the unrepaired damages on the residual earthquake resistance of a steel bridge are very scarce at present. In this paper, nonlinear time-history analysis of a steel arch bridge was performed using multi-scale hybrid model. Two strong historical records of main shock-aftershock sequences were taken as the input ground motions during the dynamic analysis. The strain response, local deformation and the accumulation of plasticity of the bridge with and without unrepaired seismic damage were compared. Moreover, the effect of earthquake sequence on crack initiation caused by low-cycle fatigue of the steel bridge was investigated. The results show that seismic damage has little impact on the overall structural displacement response during the aftershock. The residual local deformation, strain response and the cumulative equivalent plastic strain are affected to some extent by the unrepaired damage. Low-cycle fatigue of the steel arch bridge is not induced by the earthquake sequences. Damage indexes of low-cycle fatigue predicted based on different theories are not exactly the same.

• Steel and Composite Structures
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• 제15권4호
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• pp.357-377
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• 2013

In order to study the degradation and damage behaviors of steel frame welded connections, two series of tests in references with different connection constructions were carried out subjected to various cyclic loading patterns. Hysteretic curves, degradation and damage behaviours and fatigue properties of specimens were firstly studied. Typical failure modes and probable damage reasons were discussed. Then, various damage index models with variables of dissipative energy, cumulative displacement and combined energy and displacement were summarized and applied for all experimental specimens. The damage developing curves of ten damage index models for each connection were obtained. Finally, the predicted and evaluated capacities of damage index models were compared in order to describe the degraded performance and failure modes. The characteristics of each damage index model were discussed in depth, and then their distributive laws were summarized. The tests and analysis results showed that the loading histories significantly affected the distributive shapes of damage index models. Different models had their own ranges of application. The selected parameters of damage index models had great effect on the developing trends of damage curves. The model with only displacement variable was recommended because of a more simple form and no integral calculation, which was easier to be formulated and embedded in application programs.

• Journal of Yeungnam Medical Science
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• 제3권1호
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• pp.49-51
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• 1986

제왕절개술 환자 10인에게 Succinylcholine Chloride 및 atracurium을 준 결과 다음과 같은 결론을 얻었다. 1. Succinyline chloride 1mg/kg와 atracurium 0.4mg/kg를 주어 충분한 근육이완을 유지하였다. 2. 혈압과 맥박은 atracurium주사 후 의의있는 변화는 없었다. 3. 태아의 Apgar score는 1분과 5부때 8~10점으로 모두 양호한 상태였다.

• The Korean Journal of Pain
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• 제25권4호
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• pp.267-271
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• 2012

The Nuss procedure for the correction of Pectus Excavatum (PE) is associated with intense postoperative pain. Our strategy to control early postoperative pain is to combine epidural with intravenous analgesia. Our aim was to analyse our pain control strategy by reviewing all the PE cases treated at our institution. Sixty consecutive patients, aged between 12 and 26 years old, received the PE operation at our institution from January, 2007 to September, 2010. The median age was 16 (12-27) with a male/female ratio of about 7/1. An epidural catheter was employed in all the cases, with 38 patients (63%) requiring additional drugs to control pain, which remained in place for 74 hours (72-96). The pain score was higher in male patients, but lower in those younger than 16 years old. Moreover, patients that consumed benzodiazepines had a significant decrease in cumulative opioid intake (P = 0.0408). Both gender and age had an impact on pain control, while we noticed a synergistic effect between opiates and tranquillizers.

• 한국응용과학기술학회지
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• 제21권2호
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• pp.132-139
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• 2004

Film forming behavior of monodispersed model composite latexes with particle size of 190 nm, which consist of n-butyl acrylate as a soft phase monomer and methyl methacrylate as a hard phase monomer with different morphology was examined. Five different types of model latexes were used in this study such as random copolymer particle, soft-core/hard-shell particle, hard-core/soft-shell particle, gradient type particle, and mixed type particle. The film forming behavior was evaluated using pseudo on-line measurements of the cumulative weight loss, the UV transmittance, and the tensile fracture energy. Each stages of film formation I, II were not sensitive to the morphology of model latexes, but stage-ill was largely dependent on the morphology of model latexes. The chain mobility of polymer which composed the shell component was found to dominantly determine the behavior of film forming stage-III.