• Title/Summary/Keyword: cumulative effect

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Effect of Dietary Inclusion of Yacon, Ginger and Blueberry on Growth, Feed Utilization, Serum Chemistry and Challenge Test against Streptococcus iniae of Juvenile Rockfish Sebastes schlegeli (배합사료내 야콘, 생강 및 블루베리 첨가에 따른 조피볼락 (Sebastes schlegeli) 치어의 성장, 혈액성상 및 Streptococcus iniae 감염에 미치는 영향)

  • Lee, Ki Wook;Kim, Hee Sung;Cho, Sung Hwoan;Park, Chan-Il;Ha, Min-Su
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.6
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    • pp.823-829
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    • 2016
  • Yacon (YC), ginger (GG) and blueberry (BB) were added to the diet of juvenile rockfish Sebastes schlegeli to investigate the effects of these substances on growth, feed utilization and resistance to Streptococcus iniae compared to feed additive ethoxyquin. A total of 480 fish were distributed in 12 tanks and four experimental diets [control (Con), with 0.01% ethoxyquin, and 1% YC, GG and BB diets] were provided in triplicate. After an 8-week feeding trial, 20 fish from each tank were infected with Streptococcus iniae. Fish fed the BB diet had higher weight gain than fish fed the GG and Con diets. Feed efficiency of fish fed the GG and YC diets was higher than that of fish fed the BB and Con diets. The protein efficiency ratio of fish fed the GG diet was higher than that of fish fed any other diet. The cumulative mortality 54 h after infection of fish fed the Con diet was higher than that of fish fed any other diet. These results indicate that YC, GG, and BB are effective dietary additive, not only improving growth performance and feed utilization but also lowering the mortality of juvenile rockfish exposed to S. iniae.

Statistical analysis of economic activity state of workers with industrial injuries using a competing risk model (경쟁위험분석을 이용한 산재 근로자의 원직장복귀에 대한 연구)

  • Doh, Gippeum;Kim, Sooyeon;Kim, Yang-Jin
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.6
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    • pp.1271-1281
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    • 2015
  • Competing risk analysis is widely applied to analyze a failure time with more than two causes. This paper discusses the application of a competing risk model to a economic activity state of workers with occupational injuries. In particular, main interest is to estimate the distribution of restarting time two kinds of economic activities, (i) returning to original working place and (ii) finding a new job. In this paper, we applied a cumulative incidence function to evaluate their patterns under several individual factors and working place's factor. Furthermore, a subdistributional regression model is applied to estimate the effect of these factors on the returning time. According to result, worker with higher education, younger age and longer working period had a higher chance to return an original working place while one with more severe injuries and skilled laborer had longer returning time to an original working place.

A study on the application of optical fiber sensors to smart composite structures (지능형 복합재 구조물에 대한 광섬유센서의 적용에 관한 연구)

  • Jang, Tae-Seong;Kim, Ho;Lee, Jung-Ju
    • Journal of Sensor Science and Technology
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    • v.5 no.6
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    • pp.15-24
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    • 1996
  • In this study, as a part of the basic study for the application of optical fiber sensors to smart composite structures, the integrity of optical fiber sensors embedded within the composite structures was examined and then the laser signal transmitted through optical fiber sensors during the deformation of host structures was investigated. Firstly, it was found that bending test could be substituted for tensile test by comparing cumulative failure distribution based on weakest link theory and introducing the correction factor. Weibull parameters were obtained through the experiments and the correction factor was found to be applied to cumulative failure distribution derived from bending test. The integrity of embedded optical fiber sensors due to the thermal effect was evaluated by the comparison of the mean tensile strengths of cured and uncured optical fibers. Secondly, relationships between stress-strain curve obtained in tensile test of composite laminate and the intensity of laser signal transmitted through embedded optical fibers were examined and the possibility of the effective damage detection using optical fiber sensors was studied.

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An Analysis of the Spatial Range of Environmental Impact Assessment(EIA) - Focusing on Landscape Ecological Aspects - (환경영향평가대상의 공간적 평가범위 설정에 관한 연구 - 경관생태학적 측면에서 -)

  • Oh, Kyushik;Kim, Hee-Ju;Lee, Dong-Kun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.12 no.3
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    • pp.130-141
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    • 2009
  • The spatial range of EIA is mainly related to landscape ecological factors such as topography, geology, animals, and plants. Problems were detected involved land, soil, noise, oscillation, the atmosphere, animals, and plants in the natural-environment. First of all, the current EIA lacks explicit spatial ranges and sections in terms of scientific exactitude and objectivity for assessment. Secondly, there are overlapping influence-area problems resulting in cumulative impacts of unit developments that accumulate. Finally, some developments have no regard for ecological and conservational value in relation to determining which effect ecological stability, and which should be regarded as Regional Ecological Resources. Therefore, this study suggests that EIA should be improved in the following manner. First, the standard classification of landscape unit for analysis should be established 10 regulate each spatial range on a wide-landscape scale. Secondly, the impacts resulting from the interaction of overlapping influence-area developments between individual development should be assessed. Third, Minimization of the of the environmental effects is needed by applying the cumulative effects to the influence-area where developments occur in the same time or in a sequence. Fourth, individual characteristics of landscape elements such as roads, rivers, and green networks need to be considered separately in the analysis. Finally, regional ecological habitats should be included in the analysis in order to achieve stable ecosystems.

An Application of Various Drought Indices for Major Drought Analysis in Korea (우리나라의 주요가뭄해석을 위한 각종 가뭄지수의 적용)

  • Lee, Jae-Joon;Lee, Chang-Hoon
    • Journal of the Korean Society of Hazard Mitigation
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    • v.5 no.4 s.19
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    • pp.59-69
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    • 2005
  • Drought is difficult to detect and monitor, but it is easy to interpret through the drought index. The Palmer Drought Severity Index(PDSI), which is most commonly used as one of drought indices, have been widely used, however, the index have limitation as operational tools and triggers for policy responses. Recently, a new index, the Standardized Precipitation Index(SPI), was developed to improve drought detection and monitoring capabilities. The SPI has an improvement over previous indices md has several characteristics including its simplicity and temporal flexibility that allow its application for water resources on all timescales. Keetch-Byram Dought Index(KBDI) was defined as a number representing the net effect of evapotranspiration and precipitation in producing cumulative moisture deficiency in deep duff or upper soil layer. The purpose of this study is to analyze drought in Korea by using PDSI, SPI and KBDI. The result of this study suggests standard drought index by comparing of estimated drought indices. The data are obtained from Korea Meteorological Administration 56 stations over 30 years in each of the 8 sub-basins covering the whole nation. It is found that the PDSI had the advantage to detect the stage of drought resulting from cumulative shortage of rainfall, while SPI and KBDI had the advantage to detect the stage of drought resulting from short-term shortage of rainfall.

Mesothelioma in Sweden: Dose-Response Analysis for Exposure to 29 Potential Occupational Carcinogenic Agents

  • Plato, Nils;Martinsen, Jan I.;Kjaerheim, Kristina;Kyyronen, Pentti;Sparen, Par;Weiderpass, Elisabete
    • Safety and Health at Work
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    • v.9 no.3
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    • pp.290-295
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    • 2018
  • Background: There is little information on the dose-response relationship between exposure to occupational carcinogenic agents and mesothelioma. This study aimed to investigate this association as well as the existence of agents other than asbestos that might cause mesothelioma. Methods: The Swedish component of the Nordic Occupational Cancer (NOCCA) study consists of 6.78 million individuals with detailed information on occupation. Mesothelioma diagnoses recorded in 1961-2009 were identified through linkage to the Swedish Cancer Registry. We determined cumulative exposure, time of first exposure, and maximum exposure intensity by linking data on occupation to the Swedish NOCCA job-exposure matrix, which includes 29 carcinogenic agents and corresponding exposure for 283 occupations. To assess the risk of mesothelioma, we used conditional logistic regression models to estimate hazard ratios and 95% confidence intervals. Results: 2,757 mesothelioma cases were identified in males, including 1,416 who were exposed to asbestos. Univariate analyses showed not only a significant excess risk for maximum exposure intensity, with a hazard ratio of 4.81 at exposure levels 1.25-2.0 fb/ml but also a clear dose-response effect for cumulative exposure with a 30-, 40-, and 50-year latency time. No convincing excess risk was revealed for any of the other carcinogenic agents included in the Swedish NOCCA job-exposure matrix. Conclusion: When considering asbestos exposure, past exposure, even for short periods, might be enough to cause mesothelioma of the pleura later in life.

Effects of various concentrations of garlic powder and garlic extract in the diets on growth, serum chemistry and immune response of juvenile olive flounder Paralichthys olivaceus

  • Cho, Sung-Hwoan;Lee, Sang-Min;Kwon, Mun-Gyeong
    • Journal of fish pathology
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    • v.23 no.3
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    • pp.409-420
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    • 2010
  • Effects of various concentrations of garlic powder and garlic extract in the diets on growth, serum chemistry and immune response of olive flounder were determined. Thirty-five juvenile fish averaging 5.1 g were randomly distributed into 21 of 180 L flow-through tanks. Seven experimental diets with various concentrations of garlic powder (GP) and garlic extract (GE) were prepared in triplicate: GP-0 without garlic supplementation, GP-0.5, GP-1, GP-2, GP-3 and GP-5 diets containing garlic powder at the concentrations of 0.5, 1, 2, 3 and 5%, respectively at the expense of wheat flour and finally, GE-0.4 diet containing 0.4% garlic extract were prepared. At the end of the 8-week feeding trial, serum chemistry of fish was measured. In addition, twenty fish from each tank were artificially infected with E. tarda for the following 96 h to monitor cumulative mortality. Weight gain of fish fed GP-0 diet was higher than that of fish fed GP-1, GP-2, GP-3 and GP-5 diets. No difference in serum criteria (total protein, glucose, glutamate oxaloacetate transaminase, cholesterol and triglyceride levels) of olive flounder was found among the experimental diets except for glutamate pyruvate transaminase. Lysozyme activity of fish fed GP-0, GP-1, GP-3 and GE-0.4 diets was higher than that of fish fed GP-5 diet. The highest cumulative mortality was 93.3% in fish fed GP-0 diet at 96 h after E. tarda infection, followed by GP-3, GP-1, GP-5, GP-2, GP-0.5 and GE-0.4 diets. In considering these results, dietary inclusion of garlic powder and garlic extract has no distinctive positive effect on improvement in growth, serum chemistry and immune response of olive flounder in this experimental conditions, therefore, its application should be carefully considered.

Mechanical properties and failure mechanisms of sandstone with pyrite concretions under uniaxial compression

  • Chen, Shao J.;Ren, Meng Z.;Wang, Feng;Yin, Da W.;Chen, Deng H.
    • Geomechanics and Engineering
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    • v.22 no.5
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    • pp.385-396
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    • 2020
  • A uniaxial compression test was performed to analyse the mechanical properties and macroscale and mesoscale failure mechanisms of sandstone with pyrite concretions. The effect of the pyrite concretions on the evolution of macroscale cracks in the sandstone was further investigated through numerical simulations with Particle Flow Code in 2D (PFC2D). The results revealed that pyrite concretions substantially influence the mechanical properties and macroscale and mesoscale failure characteristics of sandstone. During the initial loading stage, significant stress concentrations occurred around the edges of the pyrite concretion accompanied by the preferential generation of cracks. Meanwhile, the events and cumulative energy counts of the acoustic emission (AE) signal increased rapidly because of friction sliding between the concretion and sandstone matrix. As the axial stress increased, the degree of the stress concentration remained relatively unchanged around the edges of the concretions. The cracks continued growing rapidly around the edges of the concretions and gradually expanded toward the centre of the sample. During this stage, the AE events and cumulative energy counts increased quite slowly. As the axial stress approached the peak strength of the sandstone, the cracks that developed around the edges of the concretion started to merge with cracks that propagated at the top-left and bottom-right corners of the sample. This crack evolution ultimately resulted in the shear failure of the sandstone sample around the edges of the pyrite concretions.

Flow regime analysis method by using discharge Gini coefficient (유량 지니계수를 이용한 유황분석방안)

  • Park, Tae Sun
    • Journal of Korea Water Resources Association
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    • v.54 no.12
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    • pp.1223-1232
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    • 2021
  • In this study, a new analysis method by using a "Discharge Gini Coefficient" is presented to determine the degree of inequality in daily discharge throughout the year. The Discharge Gini Coefficient can be calculated using the area relationship with the cumulative percentage of the daily mode discharge in the ascending order according to the cumulative percentage of the date of occurrence of the daily discharge throughout the year. The Discharge Gini Coefficient is presented as a value between 0 and 1, and the degree of inequality can be divided into 5 levels. The Discharge Gini Coefficient can be used to estimate the discharge stability of the downstream point relative to the upstream point. In addition, it is possible to quantify the influence of each reference discharge on the total inequality. The applicability of the Discharge Gini Coefficient was reviewed using long-term daily discharge data at eight points upstream and downstream of the four major rivers in Korea. The Discharge Gini Coefficient can also be used to analyze the discharge control effect in the downstream by the upstream dam.

Short-term Effect of Ambient Air Pollution on Emergency Department Visits for Diabetic Coma in Seoul, Korea

  • Kim, Hyunmee;Kim, Woojin;Choi, Jee Eun;Kim, Changsoo;Sohn, Jungwoo
    • Journal of Preventive Medicine and Public Health
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    • v.51 no.6
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    • pp.265-274
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    • 2018
  • Objectives: A positive association between air pollution and both the incidence and prevalence of diabetes mellitus (DM) has been reported in some epidemiologic and animal studies, but little research has evaluated the relationship between air pollution and diabetic coma. Diabetic coma is an acute complication of DM caused by diabetic ketoacidosis or hyperosmolar hyperglycemic state, which is characterized by extreme hyperglycemia accompanied by coma. We conducted a time-series study with a generalized additive model using a distributed-lag non-linear model to assess the association between ambient air pollution (particulate matter less than $10{\mu}m$ in aerodynamic diameter, nitrogen dioxide [$NO_2$], sulfur dioxide, carbon monoxide, and ozone) and emergency department (ED) visits for DM with coma in Seoul, Korea from 2005 to 2009. Methods: The ED data and medical records from the 3 years previous to each diabetic coma event were obtained from the Health Insurance Review and Assessment Service to examine the relationship with air pollutants. Results: Overall, the adjusted relative risks (RRs) for an interquartile range (IQR) increment of $NO_2$ was statistically significant at lag 1 (RR, 1.125; 95% confidence interval [CI], 1.039 to 1.219) in a single-lag model and both lag 0-1 (RR, 1.120; 95% CI, 1.028 to 1.219) and lag 0-3 (RR, 1.092; 95% CI, 1.005 to 1.186) in a cumulative-lag model. In a subgroup analysis, significant positive RRs were found for females for per-IQR increments of $NO_2$ at cumulative lag 0-3 (RR, 1.149; 95% CI, 1.022 to 1.291). Conclusions: The results of our study suggest that ambient air pollution, specifically $NO_2$, is associated with ED visits for diabetic coma.