• Title/Summary/Keyword: cross resistance

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Investigation of the effects of miniscrew-assisted rapid palatal expansion on airflow in the upper airway of an adult patient with obstructive sleep apnea syndrome using computational fluid-structure interaction analysis

  • Hur, Jae-Sik;Kim, Hyoung-Ho;Choi, Jin-Young;Suh, Sang-Ho;Baek, Seung-Hak
    • The korean journal of orthodontics
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    • v.47 no.6
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    • pp.353-364
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    • 2017
  • Objective: The objective of this study was to investigate the effects of miniscrew-assisted rapid palatal expansion (MARPE) on changes in airflow in the upper airway (UA) of an adult patient with obstructive sleep apnea syndrome (OSAS) using computational fluid-structure interaction analysis. Methods: Three-dimensional UA models fabricated from cone beam computed tomography images obtained before (T0) and after (T1) MARPE in an adult patient with OSAS were used for computational fluid dynamics with fluid-structure interaction analysis. Seven and nine cross-sectional planes (interplane distance of 10 mm) in the nasal cavity (NC) and pharynx, respectively, were set along UA. Changes in the cross-sectional area and changes in airflow velocity and pressure, node displacement, and total resistance at maximum inspiration (MI), rest, and maximum expiration (ME) were investigated at each plane after MARPE. Results: The cross-sectional areas at most planes in NC and the upper half of the pharynx were significantly increased at T1. Moreover, airflow velocity decreased in the anterior NC at MI and ME and in the nasopharynx and oropharynx at MI. The decrease in velocity was greater in NC than in the pharynx. The airflow pressure in the anterior NC and entire pharynx exhibited a decrease at T1. The amount of node displacement in NC and the pharynx was insignificant at both T0 and T1. Absolute values for the total resistance at MI, rest, and ME were lower at T1 than at T0. Conclusions: MARPE improves airflow and decreases resistance in UA; therefore, it may be an effective treatment modality for adult patients with moderate OSAS.

Switch Design of TM Type SIDO DC-DC Buck Converter for Camera Module (카메라 모듈용 TM 방식 SIDO DC-DC 벅 컨버터의 스위치 설계)

  • Choi, Hun;Lee, Dong-Keon;Jeong, Hang-Geun
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.49 no.1
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    • pp.57-63
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    • 2012
  • In this paper, a switch sizing method is proposed in order to prevent the cross-regulation in the TM type SIDO DC-DC buck converter. In TM type SIDO DC-DC buck converter, a DCM operation is required. In the DCM operation, the inductor peak current is larger than that in the CCM. Because of the larger inductor peak current and the added switch resistance, the voltage drop is increased, resulting in possible cross-regulation. To solve this problem, the switch resistance must be considered in sizing the switch. To simplify the calculation of the resistance, the inductor current was replaced by the average load current. Using the proposed method, TM type SIDO DC-DC buck converter for camera module was designed to provide two independent supply voltage(2.8 V and 1.8 V). The designed circuit was fabricated in a standard $0.35{\mu}m$ CMOS process. At a switching frequency of 1 MHz and a load current of 200 mA, a power effciency of 80.7% was achieved.

Marker Assisted Selection of Brown Planthopper Resistance and Development of Multi-Resistance to Insect and Diseases in Rice (Oryza sativa L.) (DNA 마커를 이용한 벼멸구 저항성 선발 및 복합내병충성 벼 계통 육성)

  • Lee, Jong-Hee;Yeo, Un-Sang;Cho, Jun-Hyun;Lee, Ji-Yoon;Song, You-Chun;Shin, Mun-Sik;Kang, Hang-Won;Sohn, Jae-Keun
    • Korean Journal of Breeding Science
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    • v.43 no.5
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    • pp.413-421
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    • 2011
  • The main objective of this study was to develop the multi-resistance lines to insects(brown planthopper; BPH, rice green leafhopper; GRH) and disease(blast; BL, bacterial blight; BB and rice stripe virus disease;RSV) with good grain quality and plant type by combining conventional breeding and marker assisted selection(MAS) and to eliminate the linkage drag effects between Bph1 gene and culm length, we conducted MAS of Bph1 gene in advanced backcross and double cross progenies. 'Nampyeong', 'Junam' and 'Milyang220' were used as the parent in this study. 'Milyang220' was used as the donor of brown planthopper resistance gene Bph1 with tall culm length. Two backcross progenies were developed using two recipients 'Nampyeong' carrying GRH resistance gene Grh3(t) with good grain appearance and 'Junam' harboring bacterial blight resistance gene Xa3 with short culm length. Two $BC_1$ generations were resulted from the backcrossing of the $F_1$ plants with recurrent parents 'Nampyeong' and 'Junam'. The second rounds of backcrossing($BC_2$) were derived from the cross of selected resistant $BC_1F_1$ plants based on heterozygous genotype of RM28493 linked to Bph1 gene. The double crossed population was constructed from the cross of between each heterozygous $BC_2F_1$ plants at RM28493 locus of '$Nampyeong^*3$ / Milyang220' and '$Junam^*3$ / Milyang220'., The homozygous alleles in Bph1 gene were selected using co-dominant DNA marker RM28493 in double crossed population. Eighty-five lines with multi-resistance to BL, BB, RSV, GRH and BPH were selected by bio-assay and MAS in generation of double crossing. The culm length, head rice ratio and yield of the selected multi resistance lines was ranged from 71 to 88 cm, from 51 to 93%, from 449 to 629 kg/10a. respectively. We can select a promising multi resistance line similar with 'Nampyeong' of major agronomic traits such as culm legnth, head rice ratio and yield. It was designated as Milyang265. Finally this study was developed the multi resistant varieties against to insects and diseases with the good grain quality 'Milyang265' by the advanced backcross and double cross combining MAS and it can be used as genetic resources of multi-resistance to insect and diseases in rice breeding programs.

Heat Characteristic Analysis of Stacking Type HTS Current Lead (적층형 고온초전도 전류도입선의 열 특성 해석)

  • 두호익;임성우;홍세은;윤기웅;한병성
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2001.07a
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    • pp.628-631
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    • 2001
  • Current lead is one of the first proposed devices for the application of High Temperature-Superconductor(HTSC). The current lead provides high current for electrical machine using superconductor from room temperature. Its characteristics that is zero resistance and low heat transfer rate under critical temperature lead to research for the replacement of existing current lead with HTSC. In this paper, we investigated the temperature distributions of stacking type and rod type current lead with each cross-section area and length using Nastran program and compared each temperature distribution. It is obtained from this paper that stacking type current lead has flat temperature gradient and than rod type one and more stable operation as current lead is closely related with its cross-section area and length.

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Resistive Humidity Sensor Using Phosphonium Salt-Containing Polyelectrolytes Based on the Mutually Cross-linkable Copolymers

  • Lee, Chil-Won;Gong, Myoung-Seon
    • Macromolecular Research
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    • v.11 no.5
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    • pp.322-327
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    • 2003
  • Two kinds of mutually cross-linkable copolymers were prepared to be used as humidity-sensing materials. The humidity-sensitive thin films consist of cross-linked polyelectrolytes of the following component: 4-vinylbenzyl dimethyl 2-(dimethylphosphino)ethyl phosphonium chloride (1)/ bis(2-methoxyethyl)itaconate (2)= 3/l, 2/l, 1/1 and 1/2 and 4-vinylbenzyl chloride (3)/ vinylbenzyl tributyl phosphonium chloride (4)= 3/l, 2/l, 1/1 and 1/2. The humidity sensor prepared from the reaction of 1/2= 2/l with 3/4= 2/l showed an average resistance of 723,36.2 and 2.42 ㏀ at 30, 60 and 90%RH, respectively. Temperature dependence, frequency dependence, and response time were measured and the reliability test such as water durability and long-term stability were also estimated.

Reliability - Based Decision Analysis for Structures (신뢰성에 기반한 구조물 의사결정 방법)

  • Kim, Lee-Hyeon;Kim, Dong-Geun;Han, Seo-Yeon
    • Proceedings of the KSR Conference
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    • 2011.10a
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    • pp.3208-3213
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    • 2011
  • It has regarded an attempt to design and construct more safe structures as challenges such as fate. In order to operate public facilities safely, It can be taken how to improve the resistance to applied load by increasing the cross-section of structural members or by installing reinforcement. But inevitably such a way is accompanied by an increase of construction cost or maintenance cost. To make a cost-effective construction, Reliability-based decision analysis which can judge the adequacy of investment is suggested using statistical data of the load, resistance and the maintenance cost.

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Assesment of Renewable Energy (신재생 에너지 고찰)

  • Lee, Sang-Heon;Koo, Kyoung-Whan
    • Proceedings of the KIEE Conference
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    • 2011.07a
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    • pp.2071-2072
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    • 2011
  • Withstand voltage characteristics of the nanocomposites, as a material with excellent abrasion resistance and water resistance, low shrinkage upon curing with moisture even in very good adhesion, workability is not lost. In this study, the fusion of nanoparticles and the high functionality epoxy nano-composite material produces the electricity. Degeneration of the unit based on this power structure and breakdown characteristics, efficiency and cross-measurement system as closely related organisms that can be applied to the power plant electrical efficiency of the nano-composite material is designed to develop skills.

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Evalulation of Specific Gravity in Post Member by Drilling Resistance Test

  • Park, Chun-Young;Kim, Se-Jong;Lee, Jun-Jae
    • Journal of the Korean Wood Science and Technology
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    • v.34 no.2
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    • pp.1-9
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    • 2006
  • The structural wooden members of the ancient building are deteriorated by fungi and termite over time. The deteriorate of the members causes the decrease of the specific gravity and the strength of it, so the stability of the building is threatened. Therefore, in this study, the evaluation of the specific gravity, which is correlated with the strength of the wood, was conducted in the post member using Nondestructive Evaluation (NDE) - Drilling Resistance Test (DRT). For the purpose of it, the specific gravity and drilling resistance of small specimens was measured to obtain the correlation between the specific gravity and the drilling resistance. And then, the drilling resistance test of the post members, which were expected to have the deteriorated parts, was performed. Consequently, the correlation between the specific gravity and the drilling resistance was very high ($R^2=0.89$) and the distributions of the specific gravity were evaluated for the each member. Also, the results were verified by the visual inspection of the cross section of it. Especially, the various variations of the wood member such as the deteriorated parts with termite or fungi and the crack could be detected exactly but the knot couldn't because the drill could pass by or could not penetrate the knot.

β-Adrenergic Receptor and Insulin Resistance in the Heart

  • Mangmool, Supachoke;Denkaew, Tananat;Parichatikanond, Warisara;Kurose, Hitoshi
    • Biomolecules & Therapeutics
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    • v.25 no.1
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    • pp.44-56
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    • 2017
  • Insulin resistance is characterized by the reduced ability of insulin to stimulate tissue uptake and disposal of glucose including cardiac muscle. These conditions accelerate the progression of heart failure and increase cardiovascular morbidity and mortality in patients with cardiovascular diseases. It is noteworthy that some conditions of insulin resistance are characterized by up-regulation of the sympathetic nervous system, resulting in enhanced stimulation of ${\beta}$-adrenergic receptor (${\beta}$AR). Overstimulation of ${\beta}$ARs leads to the development of heart failure and is associated with the pathogenesis of insulin resistance in the heart. However, pathological consequences of the cross-talk between the ${\beta}$AR and the insulin sensitivity and the mechanism by which ${\beta}$AR overstimulation promotes insulin resistance remain unclear. This review article examines the hypothesis that ${\beta}$ARs overstimulation leads to induction of insulin resistance in the heart.