• 제목/요약/키워드: cross protection.

검색결과 395건 처리시간 0.038초

Correlation Between food Processing-Associated Stress Tolerance and Antimicrobial Resistance in Food Pathogens

  • Woode, Benjamin Kojo;Daliri, Frank;Daliri, Eric Banan-Mwine
    • 한국식품위생안전성학회지
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    • 제35권2호
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    • pp.103-108
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    • 2020
  • 최근 최소한으로 가공된 안전한 식품에 대한 소비자의 수요가 기하급수적으로 증가하고 있다. 이러한 이유로 많은 식품가공 업체에서는 식품안전을 강화하고 유통기한을 연장하기 위한 최소한의 가공공정 중 허들기술(hurdle technology)을 적용하고 있다. 한편, 연구에 따르면 식품에 함유된 병원균을 비활성화하기 위한 공정 및 방법들은 식중독세균들의 스트레스 적응 메커니즘을 촉발시켜 심지어 후속 치료로 부터 교차 보호를 준다. 또한, 항생제와 제초제 사용과 같은 일상적인 농장 관행은 항생제 내성을 가진 병원균의 생성을 초래할 수 있다. 이러한 항생제 내성 박테리아는 식품 처리과정과 관련된 스트레스에 내성을 가질 수 있고 가공 식품에서 생존할 수 있는 가능성을 높일 수 있다. 이 리뷰에서는 식품가공과 관련된 스트레스와 항생제 내성의 상관관계에 대해 논의한다. 또한, 항균성 화합물 및 기타 식품 처리 관련 스트레스에 대한 교차 보호 수단으로서 시그마 인자(sigma factors), SOS 반응 경로(SOS response pathways) 및 유출 펌프(efflux pumps)의 사용과 같은 분자유전학적 기작에 대해서도 논의한다.

Changes in Cell Membrane Fatty Acid Composition of Streptococcus thermophilus in Response to Gradually Increasing Heat Temperature

  • Min, Bonggyu;Kim, Kkotnim;Li, Vladimir;Cho, Seoae;Kim, Heebal
    • Journal of Microbiology and Biotechnology
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    • 제30권5호
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    • pp.739-748
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    • 2020
  • In this study, a method of heat adaptation was implemented in an attempt to increase the upper thermal threshold of two Streptococcus thermophilus found in South Korea and identified the alterations in membrane fatty acid composition to adaptive response to heat. In order to develop heat tolerant lactic acid bacteria, heat treatment was continuously applied to bacteria by increasing temperature from 60℃ until the point that no surviving cell was detected. Our results indicated significant increase in heat tolerance of heat-adapted strains compared to the wild type (WT) strains. In particular, the survival ratio of basically low heat-tolerant strain increased even more. In addition, the strains with improved heat tolerance acquired cross protection, which improved their survival ratio in acid, bile salts and osmotic conditions. A relation between heat tolerance and membrane fatty acid composition was identified. As a result of heat adaptation, the ratio of unsaturated to saturated fatty acids (UFA/SFA) and C18:1 relative concentration were decreased. C6:0 in only heat-adapted strains and C22:0 in only the naturally high heat tolerant strain were detected. These results support the hypothesis, that the consequent increase of SFA ratio is a cellular response to environmental stresses such as high temperatures, and it is able to protect the cells from acid, bile salts and osmotic conditions via cross protection. This study demonstrated that the increase in heat tolerance can be utilized as a mean to improve bacterial tolerance against various environmental stresses.

Reevaluation of Photon Activation Yields of 11C, 13N, and 15O for the Estimation of Activity in Gas and Water Induced by the Operation of Electron Accelerators for Medical Use

  • Masumoto, Kazuyoshi;Matsumura, Hiroshi;Kosako, Kazuaki;Bessho, Kotaro;Toyoda, Akihiro
    • Journal of Radiation Protection and Research
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    • 제41권3호
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    • pp.286-290
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    • 2016
  • Background: Activation of air and water in the electron linear accelerator for medical use has not been considered severely. By the new Japanese regulation for protection of radiation hazard, it became indispensable to evaluate of activation of air and water in the accelerator room. The measurement of induced activity in air and water components in the electron energy region of 10 to 20 MeV is very difficult, because this energy region is close to the threshold energy region of photonuclear reactions. Then, we measured the photonuclear reaction yields of $^{13}N$, $^{15}O$, and $^{11}C$ by using the electron linear accelerator. Obtained data were compared with the data calculated by the Monte Carlo method. Materials and Methods: An activation experiment was performed at the Research Center for Electron Photon Science, Tohoku University. Highly purified $SiO_2$, $Si_3N_4$, and carbon disks were irradiated for 10 minutes by bremsstrahlung converted by a tungsten plate. Induced activity from C, N, and O was obtained. Monte Carlo calculation was performed using MCNP5 and AERY (DCHAIN-SP) to simulate the experimental condition. Cross section data were adopted the KAERI dataset. Results and Discussion: In our experiment in hospital, calculated values were not agreed with experimental values. It might be three possible reasons as the cause of this deference, such as irradiation energy, calculation procedure and cross section data. Obtained data of this work, calculated and experimental values were good agreement with each other within one order. In this work, we used KAERI dataset of photonuclear reaction instead of JENDL. Therefore, it was found that the photonuclear cross section data of light elements are most important for yield calculation in these reactions. Conclusion: Further improvement for calculation using a new dataset JENDL/PD-2015 and considering electron energy spreading will be needed.

Perceptions of Residents in Relation to Smartphone Applications to Promote Understanding of Radiation Exposure after the Fukushima Accident: A Cross-Sectional Study within and outside Fukushima Prefecture

  • Kuroda, Yujiro;Goto, Jun;Yoshida, Hiroko;Takahashi, Takeshi
    • Journal of Radiation Protection and Research
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    • 제47권2호
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    • pp.67-76
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    • 2022
  • Background: We conducted a cross-sectional study of residents within and outside Fukushima Prefecture to clarify their perceptions of the need for smartphone applications (apps) for explaining exposure doses. The results will lead to more effective methods for identifying target groups for future app development by researchers and municipalities, which will promote residents' understanding of radiological situations. Materials and Methods: In November 2019, 400 people in Fukushima Prefecture and 400 people outside were surveyed via a web-based questionnaire. In addition to basic characteristics, survey items included concerns about radiation levels and intention to use a smartphone app to keep track of exposure. The analysis was conducted by stratifying responses in each region and then cross-tabulating responses to concerns about radiation levels and intention to use an app by demographic variables. The intention to use an app was analyzed by binomial logistic regression analysis. Text-mining analyses were conducted in KH Coder software. Results and Discussion: Outside Fukushima Prefecture, concerns about the medical exposure of women to radiation exceeded 30%. Within the prefecture, the medical exposure of women, purchasing food products, and consumption of own-grown food were the main concerns. Within the prefecture, having children under the age of 18, the experience of measurement, and having experience of evacuation were significantly related to the intention to use an app. Conclusion: Regional and individual differences were evident. Since respondents differ, it is necessary to develop and promote app use in accordance with their needs and with phases of reconstruction. We expect that a suitable app will not only collect data but also connect local service providers and residents, while protecting personal information.

GDPR이 디지털 경제에 미치는 영향: 문헌 자료에 근거하여 (The Effects of GDPR on the Digital Economy: Evidence from the Literature)

  • 아랴말라 프라사드;다니엘 페레즈
    • 정보화정책
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    • 제27권3호
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    • pp.3-18
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    • 2020
  • 전세계적으로 디지털 전환이 확산됨에 따라 유럽연합(EU)은 회원국 간의 포괄적인 데이터 보호 프레임워크를 구축하기 위해 GDPR(General Data Protection Regulation)을 시행하였다. GDPR의 헌법적 뿌리를 고려할 때, EU의 규제 접근법은 다른 데이터 보호 규정들과는 차이가 있다. GDPR은 데이터 보호에 대한 개인의 권리를 강화하였다. 하지만 개인의 데이터를 수집하고 처리하는 기업에 대한 몇 가지 의무 또한 도입하였다. 본 연구에서는 정책적 관점에서 프라이버시, 특히 GDPR에 관한 기존의 문헌을 고찰하였으며, 이를 통해 데이터 규제가 경쟁, 혁신, 마케팅 활동 및 국경을 초월한 데이터 흐름에 미치는 영향을 개략적으로 리뷰 하였다. 그리고 본 연구는 프라이버시와 GDPR이 시장에 미치는 영향 사이의 절충안을 강조한다.

The Personal Data Protection Mechanism in the European Union

  • Syroid, Tetiana L.;Kaganovska, Tetiana Y.;Shamraieva, Valentyna M.;Perederiі, Оlexander S.;Titov, Ievgen B.;Varunts, Larysa D.
    • International Journal of Computer Science & Network Security
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    • 제21권5호
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    • pp.113-120
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    • 2021
  • The adoption of the General Data Protection Regulation (EU) 2016/679 transformed approaches and concepts to the implementation of the personal data protection mechanism in the European Union. Within the EU, almost all countries have adapted a new protection mechanism, which requires a study of the specifics of its use. The article intends to assess the legal provisions of the current mechanism of personal data protection in the EU. The author studied the mechanism of personal data protection under the General Data Protection Regulation (EU) 2016/679 (GDPR) based on the concept of contextual integrity and analysis of EU legislation on personal data protection. The scientific publications for 2016-2020 were reviewed for the formation of ideas of a new personal data protection mechanism in the EU, informative and transparent analysis of legal provisions. The article notes that the personal data privacy and protection is increasing, there is an ongoing unification of the legal status of personal data protection and the formation of a digital market for dissemination, exchange, control, and supervision of data. Cross-border cooperation is part of the personal data protection mechanism. The author proved that the GDPR has changed approach to personal data protection: the emphasis is now shifting to the formation of a digital market, where the EU's role in ensuring regulation is crucial. The article identifies the emergence of a new protectionist legal system and strengthening of legal provisions regarding privacy. This legal system needs unification and harmonization in accordance with national legislation, is territorially fragmented and differentiated within the EU.

통신서비스의 국경간 공급 규제정책 연구 - 한국, 미국, 일본을 중심으로 - (A Study on Cross-Border Supply Regulation Policy of Telecommunications Service - Focused on Korea, USA, Japan -)

  • 강신원;배홍균
    • 국제지역연구
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    • 제13권1호
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    • pp.445-464
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    • 2009
  • 현재 세계 여러 나라는 GATS의 통신에 관한 예외규정에 입각하여 기간통신서비스의 국경간 공급을 반경쟁행위 통제, 국내 소비자 보호, 조세부과, 국가안보 등을 이유로 규제하고 있다. 우리나라의 경우 통신서비스의 국경간 공급을 WTO 및 국내법의 규정을 통하여 부분적으로 규제를 시행하고 있으나, WTO 및 FTA 협상시 국경간 공급에 대한 규제완화를 요구받고 있다. 그러므로 규제에 대하여 실효성 파악하고 이에 대한 대응이 절실히 요구되고 있다. 따라서 본고에서는 주요국의 통신서비스의 국경간 공급 정책을 살펴보았다. 또한 주요국의 실제 규제 사례를 살펴봄으로써 우리나라의 국경간 공급 규제정책에 대한 시사점을 모색해 보았다.

지상변압기의 단락보호장치 특성연구 (Characteristics of Short-Circuit Protector in Pad-Mounted Transformer)

  • 김광화;이우영;선종호;김동명;김상준
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1995년도 하계학술대회 논문집 C
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    • pp.1350-1352
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    • 1995
  • This paper discribed the characteristic of I-t cross-over-point between current limited-fuse and explusion fuse(Bay-O-Net Fuse) and fuse protection in pad-mounted transformer that was generated internal faults and the short circuit of secondary side(load side). In the I-t cross-over-point, current limited fuse was melted when transient recovery voltage was raised rapidly.

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The Effects of Institutions on the Labour Market Outcomes: Cross-country Analysis

  • KIM, YONG-SEONG;KIM, TAE BONG
    • KDI Journal of Economic Policy
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    • 제39권4호
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    • pp.69-94
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    • 2017
  • This paper re-examines the impacts an institutional arrangement may have on labour market outcomes such as the employment and unemployment rates. Based on the results from a generalized econometric model, the generosity of unemployment insurance benefits, organized labour and active labour market policy have effects on a labour market in line with previous findings. However, taxes on labour and the degree of employment protection are found to affect neither the employment rate nor the unemployment rate. Thus, some findings in this paper validate earlier findings, whereas others do not.