• Dementia and Neurocognitive Disorders
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• v.16 no.3
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• pp.72-77
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• 2017

Background and Purpose Although sleep disturbances are common and considered a major burden for patients with Alzheimer's disease (AD), the fundamental mechanisms underlying the development and maintenance of sleep disturbance in AD patients have yet to be elucidated. The aim of this study was to examine the correlation between regional cerebral blood flow (rCBF) and sleep disturbance in AD patients using technetium-99m hexamethylpropylene amine oxime single-photon emission computed tomography (SPECT). Methods A total of 140 AD patients were included in this cross-sectional study. Seventy patients were assigned to the AD with sleep loss (SL) group and the rest were assigned to the AD without SL group. SL was measured using the sleep subscale of the Neuropsychiatric Inventory. A whole-brain voxel-wise analysis of brain SPECT data was conducted to compare the rCBF between the two groups. Results The two groups did not differ in demographic characteristics, severity of dementia, general cognitive function, and neuropsychiatric symptoms, with the exception of sleep disturbances. The SPECT imaging analysis displayed decreased perfusion in the bilateral inferior frontal gyrus, bilateral temporal pole, and right precentral gyrus in the AD patients with SL group compared with the AD patients without SL group. It also revealed increased perfusion in the right precuneus, right occipital pole, and left middle occipital gyrus in the AD with SL group compared with the AD without SL group. Conclusions The AD patients who experienced sleep disturbance had notably decreased perfusion in the frontal and temporal lobes and increased rCBF in the parietal and occipital regions. The findings of this study suggest that functional alterations in these brain areas may be the underlying neural correlates of sleep disturbance in AD patients.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.287-291
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• 2015

본 연구에서는 두 지역의 실제 상수관망에 대해서 부정류해석을 수행하였고 각각의 상수관망에 필요한 부정류피해 최소화방안을 제시하였다. 첫 번째 대상지역은 베트남 호치민으로 148개 절점과 162개의 파이프로 이루어진 소블럭 상수관망이며 두 번째 대상지역은 파주시 광탄면으로 512개 절점과 527개의 파이프로 이루어진 세 개의 소블럭 상수관망이다. 두지역의 상수관망은 지형적면이나 규모면에서 다른 모습을 하고 있기 때문에 부정류해석 시 발생가능한 피해유형이 틀린 것으로 나타났다. 호치민의 경우 배수지의 높이가 낮고 도시 내 표고차가 없어서 관망 내 평균수압이 $1kg/cm^2$을 약간 상회하는 수준으로 수압이 낮고 수압차 역시 작다. 따라서 상수관망에서 일어날 수 있는 소요수량의 변화나 소화전 사용과 같은 작은 변화에도 역류발생이 빈번히 일어나는 것으로 나타났으며 역류발생이 잦은 파이프를 선정할 수 있었다. 상당히 많은 파이프에서 단기간 역류가 발생하는 것을 확인할 수 있었다. 짧은 기간에 발생하는 변화에 대한 단기간 역류는 교차연결(Cross-Connection)의 문제를 야기할 수 있다. 따라서 역류발생이 빈번히 일어나는 파이프 주위에 check valve나 역지밸브등의 설치를 통해 역류로 인한 피해를 최소화할 수 있다. 파주시 광탄면 지역의 소블럭 집합으로써 고저차가 많은 지역이다. 배수지 밸브개폐 시 발생 가능한 수충격에 대한 시뮬레이션과 펌프장정지로 인해 발생할 수 있는 수충격에 발생 시뮬레이션을 수행하였고 관망내에서 자주 발생하는 밸브개폐로 인한 시뮬레이션을 수행하였다. 그 결과 광탄의 경우 수충격 발생위험 지점은 배수지 근처로 나타났고 수격압이 최대 $2.5kg/cm^2$에서 $3.0kg/cm^2$까지 발생 가능한 것으로 나타났고 밸브개폐시간이 1-2초 지연되어도 상당히 큰 수격압을 줄일 수 있는 것으로 나타났다. 수충격압이 크게 발생할 수 있는 지역에 수충격피해 최소화를 위해 surge tank와 같은 장치를 설치해야 한다. 또한 발생가능한 수격압의 크기를 통계적기법을 통해 확률밀도함수로 나타낼 수 있었다. 이 결과는 앞으로 상수관망의 설계나 운영에서 수충격피해 방지 장치 및 설비를 시공할 때 장치의 규모나 용량을 결정할 때 유용한 정보가 될 것으로 판단된다.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.221-221
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• 2017

본 연구에서는 국내는 물론 전 세계적으로 널리 사용되고 있는 SWAT 모형을 대상으로 하천 단면 관련 입력변수가 유량 및 수질 모의에 미치는 영향을 분석하였다. 본 연구에서는 남한강 상류 충주댐 유역을 연구대상지역으로 연구를 진행하였으며, 충주댐 유역 내 소유역 중에서 국립환경과학원에서 국내 하천을 대상으로 구축한 한국형 Reach File(KRF) 내 실측 하천단면 정보가 존재하는 소유역에 대하여 실측 하천단면 정보를 적용하였다. 또한 본 연구를 위해 사용자가 구축한 소유역별 하천단면 정보 입력 자료를 통해 수문 및 수질 모의가 가능하도록 기존 SWAT 모형의 엔진 소스코드를 개선하였다. 유역 최종 유출구와 KRF의 실측 하천단면 정보를 적용한 소유역의 유량과 수질(유사량)에 대해서 실측 하천단면 정보 적용 전과 후의 모의 결과를 비교한 결과 유역 최종 유출구에서는 유량 및 유사량 모두 큰 변화는 나타나지 않았다. 이는 전체 유역 중 실제 하천단면 정보를 적용한 소유역의 비중이 작기 때문으로 판단되었다. 하지만 하천단면 정보를 적용한 소유역에서는 유량 및 유사량 모두 적용 전/후 차이가 나타났다. 특히 저유량 부분에서의 유사량이 큰 변화를 나타냈다. 하지만 본 연구에서 실측 하천단면 정보를 적용한 소유역은 유량 및 수질관측소가 위치하지 않는 미계측 유역으로써 실제 유량 및 수질 모의 정확도 향상 여부에 대한 평가가 불가능하였다. 따라서 향후 유량 또는 수질 관측이 이뤄지고 있는 계측 유역을 대상으로 실제 모형 모의 정확도 향상 여부에 대한 분석이 필요할 것으로 판단된다.

• The Journal of Korean Physical Therapy
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• v.33 no.4
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• pp.179-186
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• 2021

Background: Patients with advanced asthma and chronic obstructive pulmonary disease (COPD) have postural deviations such as thoracic hyperkyphosis, forward shoulder posture (FSP) due to an increase in head and cervical protraction, reduced shoulder range of motion and a corresponding increase in scapula elevation and upward rotation. Unlike congenital vertebral kyphosis that are permanent and rigid deformities with bony and other structural deformations which cause respiratory impairment, these deformities in these patients may be more flexible. Since the thoracic hyperkyphosis has been implicated as having adverse health consequences it is necessary to evaluated the relationship between thoracic kyphosis and cardiopulmonary functions of patients with COPD and asthma. Methods: It was a cross-sectional analytical study. Eighty-four eligible patients with COPD and asthma were recruited from the Respiratory Unit, Department of Medicine, Lagos University Teaching Hospital (LUTH), and basic anthropometric parameters, pulmonary parameters, cardiovascular parameters, thoracic kyphosis (Cobb) angle and presence of respiratory symptoms of participants were assessed. Data was analyzed using SPSS version 20. Results: There was no significant correlation between the thoracic kyphosis and selected pulmonary parameters (Forced Expiratory Volume in one second (FEV1, p=0.36), Forced Vital Capacity (FVC, p=0.95), Peak Expiratory Flow Rate (PEFR, p=0.16), Thoracic expansion (TE, p=0.27)/cardiovascular parameters (Systolic Blood Pressure (SBP, p=0.108), Diastolic Blood Pressure (DBP, p=0.17) and Pulse Rate (PR, p=0.93) as well as the respiratory symptoms (SGRQ scores, p=0.11) in all subjects. Conclusion: There was no relationship between thoracic kyphosis and selected pulmonary/cardiovascular parameters as well as respiratory symptoms in patients with COPD and asthma.

• Journal of Chest Surgery
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• v.54 no.5
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• pp.383-388
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• 2021

Background: Achieving external access to and manual occlusion of the left atrial appendage (LAA) during minimally invasive mitral valve surgery (MIMVS) through a small right thoracotomy is difficult. Occlusion of the LAA using an epicardial closure device seems quite useful compared to other surgical techniques. Methods: Fourteen patients with atrial fibrillation underwent MIMVS with concomitant surgical occlusion of the LAA using double-layered endocardial closure stitches (n=6, endocardial suture group) or the AtriClip Pro closure device (n=8, AtriClip group) at our institution. The primary safety endpoint was any device-related adverse event, and the primary efficacy endpoint was successful complete occlusion of blood flow into the LAA as assessed by transthoracic echocardiography at hospital discharge. The primary efficacy endpoint for stroke reduction was the occurrence of ischemic or hemorrhagic neurologic events. Results: All patients underwent LAA occlusion as scheduled. The cardiopulmonary bypass and aortic cross-clamp times in the endocardial suture group and the AtriClip group were 202±39 and 128±41 minutes, and 213±53 and 136±44 minutes, respectively (p=0.68, p=0.73). No patients in either group experienced any device-related serious adverse events, incomplete LAA occlusion, early postoperative stroke, or neurologic complication. Conclusion: Epicardial LAA occlusion using the AtriClip Pro during MIMVS in patients with mitral valve disease and atrial fibrillation is a simple, safe, and effective adjunctive procedure.

• Journal of The Korean Society of Agricultural Engineers
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• v.61 no.4
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• pp.33-42
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• 2019

In this study, the channel and floodplain widths are indirectly measured for three different watersheds using satellite images to reflect the shape of Korean channels in the Soil and Water Assessment Tool (SWAT) model. For measuring the channel and floodplain widths, multiple satellite images were referred to ensure the widest width of certain points. In the single channel, the widths at the multiple points were measured. Based on the measured data, the regression equations were derived to estimate the channel and floodplain widths according to watershed areas. Applying these developed equations, this study evaluated the effect of the change of channel and floodplain widths on the SWAT simulation by comparing to the measured streamflow data. The developed equations estimated larger channel width and smaller floodplain compared with those calculated in the current SWAT model. As shown in the results, there was no considerable changes in the predicted streamflow using the current and developed equations. However, the flow velocity and channel depth calculated from the developed equations were smaller than those of the current equations. The differences were caused by the effect of different channel geometries used for calculating the hydraulic characteristics. The channel geometries also affected the water quality simulation in channels because the hydraulic characteristics calculated by the channel geometries are directly related to the water quality simulation. Therefore, application of the river cross-sectional regression equation reflecting the domestic stream shape is necessary for accurate water quantity / quality and water ecosystem simulation using hydrological model.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.2
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• pp.1-7
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• 2019

Recently, multimedia streaming service has been activated, and the demand for high-quality multimedia convergence contents services is predicted to increase significantly in the future. The issues of the increasing network load due to the rise of multimedia streaming traffic must be addressed in order to provide QoS guaranteed services. To do this, an efficient network resource management and mobility support technologies are needed through seamless mobility support for heterogeneous networks. Therefore, in this paper, an MIH technology was used to recognize the network situation information in advance and reduce packet loss due to handover delays, and an ACLMIH-FHPMIPv6 is designed that can provide an intelligent interface through introducing a hierarchical mobility management technique in FPMIPv6 integrated network.

• Korean Journal of Optics and Photonics
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• v.32 no.5
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• pp.230-234
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• 2021

Relief of thermal stress has received great attention, to improve the beam quality and stability of high-power laser diodes. In this paper, we investigate a microtrench structure engraved around a laser-diode chip-on-submount (CoS) to relieve the thermal stress on a laser-diode bar (LD-bar), using the SolidWorks® software. First, we systematically analyze the thermal stress on the LD-bar CoS with a metal heat-sink holder, and then derive an optimal design for thermal stress relief according to the change in microtrench depth. The thermal stress of the front part of the LD-bar CoS, which is the main cause of the "smile effect", is reduced to about 1/5 of that without the microtrench structure, while maintaining the thermal resistance.

• Physical Therapy Rehabilitation Science
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• v.10 no.1
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• pp.40-47
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• 2021

Objective: The purpose of this study is to prove the reliability and validity of the Power breath K5 and to compare it with pony FX. Power breathe K5 is one type of device can assess automatically Maximum inspiratory pressure (MIP), Peak inspiratory pressure, Peak inspiratory flow (PIF). Design: Cross-sectional study. Methods: Thirty-five COPD patients participated in the test to investigate for the intra relater reliability and concurrent validity. The tests MIP, Vital capacity (VC), PIF were measured by Powerbreathe K5 and Pony Fx. Data was analyzed by intraclass correlation reliability (ICC) value and a standard error of measurement and Bland-Altman plots for reliability and pearson correlation for validity. Results: Intra rater reliability of the Powerbreathe K5 was very high at MIP (ICC=0.977 95%CI 0.956~0.989, SEM=8.665, MDC=0.295), PIF (ICC=0.966 95%CI 0.933~0.93, SEM=8.665, MDC=0.295), VC (ICC=0.949 95CI 0.902~0.974, SEM=0.042, MDC=0.116). The Powerbreath K5 was significant correlation compared with Pony Fx in assessment for MIP (r=0.971, p<0.05) and vital capacity (r=0.534, p<0.05). Conclusion: In this study, We investigated the clinical usefulness of the Powerbreath K5 in evaulating the MIP, VC and PIF with COPD patients with high reliability and validity.

• Transactions of the Korean hydrogen and new energy society
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• v.24 no.2
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• pp.150-159
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• 2013

To enhance the performance of SEWGS system by holding the WGS catalyst in a SEWGS reactor using bed inserts, effects of insert geometry and shape of WGS catalysts on CO conversion were measured and investigated. Small scale fluidized bed reactor was used as experimental apparatus and WGS catalyst (particle and tablet) and sand were used as bed materials. The parallel wall type and cross type bed inserts were used to hold the WGS catalysts. The CO conversion with steam/CO ratio was determined based on the exit gas analysis. The measured CO conversion using the bed inserts showed high value comparable to physical mixing cases. Moreover, gas flow direction was confirmed by bed pressure drop measurement for each case. Most of input gas flowed through the catalyst side when we charged tablet type catalyst into the bed insert and this can cause low $CO_2$ capture efficiency because the possibility of contact between input gas and $CO_2$ absorbent is low in this case. New bed insert geometry was proposed based on the results from this study to enhance contact between input gas and WGS catalyst and $CO_2$ absorbent.