• 한국콘텐츠학회논문지
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• 제18권6호
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• pp.38-49
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• 2018

근거기반실무 간호교육은 학습자의 수준에 따라 단계적으로 경험하며 숙련되도록 이끌어야한다. 본 연구는 근거기반실무의 일부를 통합한 간호학과 2학년의 기본간호학 수업을 운영하고 근거기반실무의 기초역량 향상에 대한 효과를 검증하였다. 연구 설계는 비동등성 대조군 전후 유사실험설계이었다. 대상자는 2개 대학교의 간호학과 2학년 재학생 108명이었다. 실험군은 2016년 2학기 15주 수업기간 중 총 8주, 24시간의 근거기반실무를 활용한 기본간호학 수업에 참여하였고 대조군은 일반적 기본간호학 수업에 참여하였다. 자료는 자가보고형의 문제해결 적극성, 근거기반실무 적용의도, 그리고 비판적 사고성향 측정도구로 수집하였다. 수집된 자료는 SPSS/WIN 23.0 program을 이용하여 동질성은 Chi-square 검정과 독립표본 t-검정으로, 가설 검정은 독립표본 t-검정으로 분석하였다. 분석 결과 실험군은 대조군에 비해 문제해결 적극성과 근거기반실무 적용의도에서 유의한 증가를 보였다. 그러나 비판적 사고는 두 군 간에 차이가 없었다. 근거기반실무를 활용한 기본간호학 수업은 저학년 학생의 근거기반실무 기초역량인 문제해결 적극성과 근거기반실무 적용의도의 증가에 효과적이었다. 근거기반실무에 대한 학년별 목표에 적합한 교과과정에 의한 간호학생들의 근거기반실무 역량과 비판적 사고의 향상에 대한 장기적 노력이 더 필요하다.

• 중환자간호학회지
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• 제6권2호
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• pp.12-23
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• 2013

Purpose: This study was conducted to develop a Korean version of evidence-based enteral tube feeding (ETF) guidelines through adaptation of existing ETF guidelines. Methods: The guideline adaptation process was conducted into 24 steps according to a manual for guideline adaptation version 2.0 developed by NECA. Results: The adapted ETF nursing practice guideline was consisted of 9 domains and 20 recommendations, including confirmation of tube placement, risk of aspiration, assessment gastric residual volume, body positioning, treating feeding tube occlusion, administration rate, medication, tube flushes, and interruption of feeding. The results of the grading of recommendations assessment by expert penal showed that 8 recommendations in Grade A, 4 in grade B, and 8 in Grade C were emerged from the process. The range of content validity index scores by expert penal was 0.8-1.0. Conclusion: It is expected that the adapted ETF nursing practice guideline could be helpful for nurses to practice evidence-based ETF for their patients.

• 논리연구
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• 제15권1호
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• pp.107-154
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• 2012

이전 논문(2009)에서 나는 잠자는 미녀 역설에 대한 한 가지 해결책을 제시하였는데, 그에 의하면 미녀가 동전 앞면에 월요일에 부여하는 확률은 1/2보다 낮아야 한다. 이것은 물론 1/3주의에 유리한 결론이다. 그렇지만 내가 1/3주의를 성공적으로 옹호했다고 할지라도, 한 가지 중요한 물음이 남는다: 왜 1/2주의는 틀렸는가? 그들의 주요 논변은 간단하다: 잠자는 미녀는 동전이 어떻게 땅에 떨어지는지에 대한 새로운 증거를 받지 못했기 때문에, 그녀가 그 가능성에 부여하는 확률은 이전과 같아야 한다. 이제 다음 사실에 주목해 보자: 만일 1/3입장이 옳다면 잠자는 미녀 역설은 이른바 오래된 증거 문제의 새로운 예가 될 것이다. 이 논문에서 나는 새롭고 직접적으로 관련된 증거가 없음에도 왜 잠자는 미녀가 그녀의 믿음의 정도를 바꿀 수 있는지 대니얼 가버(1983)가 오래된 증거 문제에 대해 내놓은 해결책을 가지고 설명할 것이다.

• Journal of Information Processing Systems
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• 제15권6호
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• pp.1472-1488
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• 2019

Critical elements in the China's Lunar Exploration reside in that the lunar rover travels over the surrounding undetermined environment and it conducts scientific exploration under the ground control via teleoperation system. Such an interplanetary transportation mission teleoperation system belongs to the ground application system in deep space mission, which performs terrain reconstruction, visual positioning, path planning, and rover motion control by receiving telemetry data. It plays a vital role in the whole lunar exploration operation and its so-called trustworthy evidence must be assessed before and during its implementation. Taking ISO standards and China's national military standards as trustworthy evidence source, the net assessment model and net assessment method of teleoperation system are established in this paper. The multi-dimensional net assessment model covering the life cycle of software is defined by extracting the trustworthy evidences from trustworthy evidence source. The qualitative decisions are converted to quantitative weights through the net assessment method (NAM) combined with fuzzy analytic hierarchy process (FAHP) and entropy weight method (EWM) to determine the weight of the evidence elements in the net assessment model. The paper employs the teleoperation system for interplanetary transportation as a case study. The experimental result drawn shows the validity and rationality of net assessment model and method. In the final part of this paper, the untrustworthy elements of the teleoperation system are discovered and an improvement scheme is established upon the "net result". The work completed in this paper has been applied in the development of the teleoperation system of China's Chang'e-3 (CE-3) "Jade Rabbit-1" and Chang'e-4 (CE-4) "Jade Rabbit-2" rover successfully. Besides, it will be implemented in China's Chang'e-5 (CE-5) mission in 2019. What's more, it will be promoted in the Mars exploration mission in 2020. Therefore it is valuable to the development process improvement of aerospace information system.

• Tuberculosis and Respiratory Diseases
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• 제57권4호
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• pp.377-380
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• 2004

유미흉은 주로 악성종양에 의한 흉관의 폐쇄, 유미뇨는 림프관과 요관과의 누공형성이 주된 원인이다. 저자들은 유미흉의 원인으로 섬유육종에 의한 흉관폐쇄, 유미뇨의 원인으로 요로계와 림프관의 누공형성을 의심하였으나 검사상 증거를 찾을 수 없어 특발성 유미흉 및 특발성 유미뇨로 진단한 1예를 문헌고찰과 함께 보고하는 바이다.

• 중환자간호학회지
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• 제11권2호
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• pp.75-85
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• 2018

Purpose : The purpose of this study was to examine the possible direction of critical care nursing research in the future by analyzing the trends of recent Korean studies. Method : Using a database search, we selected 263 articles on critical care nursing that were published in Korean journals between 2008 and 2017. Then, we conducted an integrative review of the contents of the selected articles and analyzed the English abstracts using the relevant packages and functions of the R program. Results : The number of studies concerning critical care nursing has increased over the 10-year period, and the specific topic of each study has diversified according to the time at which it was conducted. In terms of quality, the majority of the research was published in high-level academic journals. The key words regularly studied over the past decade were: knowledge, delirium, education, restraint, stress, and infection. Studies related to vancomycin-resistant enterococci infection, compliance, and standards have decreased, while studies related to death, communication, and safety have increased. Conclusion : Randomized controlled trials and protocol research for evidence-based critical care need to be conducted, as does research on family involvement. The key word analysis of unstructured text used in this study is a relatively new method; it is suggested that this method be applied to various critical care nursing research and develop it methodologically.

• 융합정보논문지
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• 제11권8호
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• pp.224-231
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• 2021

본 연구의 목적은 비판적 사고 집중교육을 포함한 교과 교육이 간호대학생의 비판적 사고 성향을 향상시키는지를 알아보기 위함이다. 연구대상은 2학년 173명이었고 교육은 2시간씩 3회 총 6시간의 비판적 사고 집중교육과 간호과정과 비판적 사고 강의시간에 지속적인 교육을 시행하였다. 사전·사후 설문은 개강 첫 주와 14주차에 실시하였으며 수집된 자료는 IBM SPSS 21.0으로 분석하였다. 연구결과 교육 전·후 비판적 사고 성향의 평균 평점이 상향되었으며(3.65±0.41→3.83±0.46, t=6.796, p<.001) 하부 항목 중 교육 전 가장 낮은 점수를 보였던 창의성이 가장 많이 상향되었다(3.13±0.78→3.43±0.86, t=5.842, p<.001). 비판적 사고 관련 교육의 효과는 확인되었으나 세부 항목별 관련성에 대한 근거가 부족하며 교육의 질 보장을 위한 반복연구와 교수방법 개발 및 효과 검증을 위한 도구 개발이 필요함을 제언한다.

• Progress in Superconductivity
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• 제3권1호
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• pp.5-12
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• 2001

Our experimental research focuses on manipulating pinning deflects to alter the phase diagram of vortex matter, creating new vortex phases. Vortex matter offers a unique opportunity for creating and studying these novel phase transitions through precise control of thermal, pinning and elastic energies. The vortex melting transition in untwinned YB $a_2$C $u_3$ $O_{7-}$ $\delta$/ crystals is investigated in the presence of disorder induced by particle irradiation. We focus on the low disorder regime, where a glassy state and a lattice state can be realized in the same phase diagram. We follow the evolution of the first order vortex melting transition line into a continuous transition line as disorder is increased by irradiation. The transformation is marked by an upward shift in the lower critical point on the melting line. With columnar deflects induced by heavy ion irradiation, we find a second order Bose glass transition line separating the vortex liquid from a Bose glass below the lower critical point. Furthermore, we find an upper threshold of columnar defect concentration beyond which the lower critical point and the first order melting line disappear together. With point deflect clusters induced by proton irradiation, we find evidence for a continuous thermodynamic transition below the lower critical point..

• Journal of Ginseng Research
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• 제34권3호
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• pp.160-167
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• 2010

Asian ginseng (Panax ginseng) and American ginseng (Panax quinquefolius L.) are the two most recognized ginseng botanicals. It is believed that the ginseng saponins called ginsenosides are the major active constituents in both ginsengs. Although American ginseng is not as extensively studied as Asian ginseng, it is one of the best selling herbs in the US, and has garnered increasing attention from scientists in recent years. In this article, after a brief introduction of the distribution and cultivation of American ginseng, we discuss chemical analysis of saponins from these two ginsengs, i.e., their similarities and differences. Subsequently, we review pharmacological effects of the saponins, including the effects on the cardiovascular system, immune system, and central nervous system as well as the anti-diabetes and anti-cancer effects. These investigations were mainly derived from American ginseng studies. We also discuss evidence suggesting that chemical modifications of ginseng saponins would be a valuable approach to develop novel compounds in drug discovery.

• The Korean Journal of Physiology and Pharmacology
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• 제27권2호
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• pp.131-141
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• 2023

Compelling evidence has demonstrated the critical role of circular RNAs (circRNAs) during lung adenocarcinoma (LUAD) progression. Herein, we explored a novel circRNA, circ_0129047, and detailed its mechanism of action. The expression of circ 0129047, microRNA-665 (miR-665), and protein tyrosine phosphatase receptor type B (PTPRB) in LUAD tissues and cells was determined using reverse transcription quantitative polymerase chain reaction and Western blotting. Cell Counting Kit8 and colony formation assays were conducted to detect LUAD cell proliferation, and western blotting was performed to quantify apoptosis-related proteins (Bcl2 and Bax). Luciferase reporter and RNA immunoprecipitation assays were used to validate the predicted interaction between miR-665 and circ_0129047 or PTPRB. A xenograft assay was used for the in vivo experiments. Circ_0129047 and PTPRB were downregulated in LUAD tissues and cells, whereas miR-665 expression was upregulated. Overexpression of circ_0129047 suppresses LUAD growth in vivo and in vitro. Circ_0129047 is the target of miR-665, and the miR-665 mimic ablated the antiproliferative and pro-apoptotic phenotypes of LUAD cells by circ_0129047 augmentation. MiR-665 targets the 3'UTR of PTPRB and downregulates PTPRB expression. PTPRB overexpression offsets the pro-proliferative potential of miR-665 in LUAD cells. Circ_0129047 sequestered miR-665 and upregulated PTPRB expression, thereby reducing LUAD progression, suggesting a promising approach for preventing LUAD.