• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2000년도 가을 학술발표회 논문집
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• pp.705-712
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• 2000

The fluid generally flows through fractures in crystalline rocks where most of underground storage facilities are constructed because of their low hydraulic conductivities. The fractured rock is better to be conceptualized with a discrete fracture concept, rather continuum approach. In the aspect of fluid flow in underground, the simultaneous flow of groundwater and gas should be considered in the cases of generation and leakage of gas in nuclear waste disposal facilities, air sparging process and soil vapor extraction for eliminating contaminants in soil or rock pore, and pneumatic fracturing for the improvement of permeability of rock mass. For the purpose of appropriate analysis of groundwater-gas flow, this study presents an unsteady-state multi-phase FEM fracture network simulator. Numerical simulation has been also conducted to investigate the hydraulic head distribution and air tightness around Ulsan LPG storage cavern. The recorded hydraulic head at the observation well Y was -5 to -10 m. From the results obtained by the developed model, it shows that the discrete fracture model yielded hydraulic head of -10 m, whereas great discrepancy with the field data was observed in the case of equivalent continuum modeling. The air tightness of individual fractures around cavern was examined according to two different operating pressures and as a result, only several numbers of fractures neighboring the cavern did not satisfy the criteria of air tightness at 882 kPa of cavern pressure. In the meantime, when operating pressure is 710.5 kPa, the most areas did not satisfy air tightness criteria. Finally, in the case of gas leaking from cavern to the surrounding rocks, the resulted hydraulic head and flowing pattern was changed and, therefore, gas was leaked out from the cavern ceiling and groundwater was flowed into the cavern through the walls.

• 대한한의학회지
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• 제40권3호
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• pp.139-176
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• 2019

Objectives: This study aims to review the herbal medicines containing substances banned by World Anti-Doping Agency(WADA), and to consider criteria for the using of herbal medicines. Methods: Using foreign(Pubmed, Cochrane, Embase, Google Scholar, WANFANG, CiNii) and domestic databases (NDSL, OASIS, RISS), we analyzed the content and pharmacokinetics of the prohibited substances in herbal medicines. Results: Herbal medicines containing the prohibited substances proposed in Korea, China, and Japan are Ephedrae Herba, Cannabis Semen, Strychni Semen, Strychni Ignatii Semen, Pinelliae Tuber, Rhizoma Pinelliae, Chelidonii Herba, Papaveris Fructus Deseminatus, Liriopis Tuber, Rehmanniae Radix Recens, Cistanchis Herba, Ponciri Fructus Immaturus, Aurantii Fructus Immaturus, Moschus, Testudinis Plastrum, Otariae Testis et Penis, and Hominis Placenta. Of these, when using Ephedrae Herba, Cannabis Semen, Strychni Semen, Moschus, Strychni Ignatii Semen, and Otariae Testis et Penis, caution is needed in relation to the doping test. Other herbal medicines are considered safe for the doping test. In addition, by analyzing data related to higenamine added to the WADA's prohibited list of doping since 2017, we don't recommend using Nelumbinis Plumula. And in the case of the other herbal medicines containing higenamine, it is considered that care should be taken in doping test depending on the amount of usage. Conclusions: As a result of analyzing the herbal medicines which are in prohibited list about doping, we were able to know the criteria and precautions to use when prescribing the herbal medicines. Further research will be needed about common used herbal medicines and the amount of detection depending on extraction and boiling method.

• 대한약침학회지
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• 제26권1호
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• pp.38-43
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• 2023

Objectives: Psychiatric symptoms in epilepsy are very common, and the most common symptoms are depression, insomnia, and anxiety. These symptoms not only lower the quality of life of epilepsy patients, but also elevate the risk of epileptic seizures. There are no specific criteria for the available antiepileptic drugs to ameliorate these symptoms in patients with epilepsy, and there is a lack of evidence to support the efficacy and safety of existing drugs. The Shugan Jieyu capsule (SJC) is a traditional herbal medicine composed of Acanthopanax senticosus and Hypericum perforatum and is reported to be effective in relieving psychiatric symptoms. The purpose of this study was to assess the efficacy of SJC as a treatment for psychiatric symptoms in epilepsy patients. Methods: Electronic databases will be investigated for publications in English, Korean, Japanese, and Chinese. The participants of the study are epilepsy patients with psychiatric symptoms diagnosed using any validated criteria. All types of controls will be compared-placebo, conventional treatments, and no treatment-to groups treated with SJC or modified SJC. We will measure the degree of improvement in psychiatric symptoms and check epileptic symptoms, such as the frequency of seizures. The study selection and data extraction will be performed by two independent reviewers, who will also assess methodological quality using the risk-of-bias tool by Cochrane. We will use Review Manager software (RevMan) to carry out all statistical analyses. Results: This systematic review and meta-analysis will be performed in accordance with the PRISMA-P statement. Conclusion: This systematic review is the first study to assess the efficacy and safety of SJC for the treatment of psychiatric symptoms in epilepsy. We expect that this study will provide clinically applicable evidence for patients with epilepsy when selecting drug treatments.

• 한국CDE학회논문집
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• 제10권6호
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• pp.444-454
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• 2005

Recently, the requirements of multi-resolution models of a solid model, which represent an object at multiple levels of feature detail, are increasing for engineering tasks such as analysis, network-based collaborative design, and virtual prototyping and manufacturing. The research on this area has focused on several topics: topological frameworks for representing multi-resolution solid models, criteria for the level of detail (LOD), and generation of valid models after rearrangement of features. As a solution to the feature rearrangement problem, the new concept of the effective zone of a feature is introduced in the former part of the paper. In this paper, we propose a feature-based non-manifold modeling system to provide multi-resolution models of a feature-based solid or non-manifold model on the basis of the effective feature zones. To facilitate the implementation, we introduce the class of the multi-resolution feature whose attributes contain all necessary information to build a multi-resolution solid model and extract LOD models from it. In addition, two methods are introduced to accelerate the extraction of LOD models from the multi-resolution modeling database: the one is using an NMT model, known as a merged set, to represent multi-resolution models, and the other is storing differences between adjacent LOD models to accelerate the transition to the other LOD. We also suggest the volume of the feature, regardless of feature type, as a criterion for the LOD. This criterion can be used in a wide range of applications, since there is no distinction between additive and subtractive features unlike the previous method.

• 한국환경복원기술학회지
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• 제27권1호
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• pp.17-29
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• 2024

This study was conducted to select the restoration priority of forest damage sites in Gangwon Province. We first identified the status of damaged areas. We then selected restoration evaluation indicators through a literature review. We then set weights for these indicators through expert surveys. We next acquired data that can represent these indicators and spatially mapped them. Finally, we prioritized the restoration target sites by taking the weights. The results of the study showed that disaster sensitivity and ecologicality are important criteria for selecting the restoration priority of damage sites. The analysis showed that damage sites in Doam, Jeongseon, Samcheok and Inje are in urgent need of restoration. The results of this study are significant in that they selected the restoration priority of damage sites in Gangwon Province based on the restoration priority evaluation criteria selected based on expert surveys. However, the priority restoration areas derived from the results of this study are not actually implementing restoration projects at present. Therefore, it is judged that it would be efficient in various aspects to establish the restoration priority area based on scientific analysis techniques and carry out the project for efficient implementation of the restoration project. In this study, it can be pointed out that the priority of restoration of damage sites was derived based on data from the past due to the limitation of data acquisition. However, the fact that the priority restoration area inferred based on past data has been restored over time has improved the reliability of the study by verifying the usefulness of the priority extraction technique. In the future, if the priority of damage sites is extracted by extracting the restoration target area boundary through the latest data based on the methodology applied in this study, it is considered that it will be available as a result that can be applied to the field.

• 대한의용생체공학회:의공학회지
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• 제32권2호
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• pp.134-143
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• 2011

The selection of meaningful clinical tests and its reference values from a high-dimensional clinical data with imbalanced class distribution, one class is represented by a large number of examples while the other is represented by only a few, is an important issue for differential diagnosis between similar diseases, but difficult. For this purpose, this study introduces methods based on the concepts of both discernibility matrix and function in rough set theory (RST) with two discretization approaches, equal width and frequency discretization. Here these discretization approaches are used to define the reference values for clinical tests, and the discernibility matrix and function are used to extract a subset of significant clinical tests from the translated nominal attribute values. To show its applicability in the differential diagnosis problem, we have applied it to extract the significant clinical tests and its reference values between normal (N = 351) and abnormal group (N = 101) with either cholecystitis or cholelithiasis disease. In addition, we investigated not only the selected significant clinical tests and the variations of its reference values, but also the average predictive accuracies on four evaluation criteria, i.e., accuracy, sensitivity, specificity, and geometric mean, during l0-fold cross validation. From the experimental results, we confirmed that two discretization approaches based rough set approximation methods with relative frequency give better results than those with absolute frequency, in the evaluation criteria (i.e., average geometric mean). Thus it shows that the prediction model using relative frequency can be used effectively in classification and prediction problems of the clinical data with imbalanced class distribution.

• 대한통합의학회지
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• 제12권3호
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• pp.237-247
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• 2024

Purpose : This study aimed to systematically review the effectiveness of nursing interventions for patients receiving extracorporeal membrane oxygenation (ECMO). As the use of ECMO increases in critical care settings, it is important to understand how nursing interventions affect patient outcomes, survival, and complication rates. Methods : This systematic review followed the preferred reporting items for systematic reviews and meta-analysis guidelines. A literature search was performed using terms related to ECMO and nursing interventions in several international electronic databases including CINAHL, Embase, MEDLINE, and Web of Science. Studies were screened and selected according to predefined eligibility criteria, focusing on those that evaluated the impact of nursing interventions on adult. Data extraction and risk-of-bias assessment were independently performed by two researchers. Results : A total of 647 studies were identified, and seven met the inclusion criteria for qualitative analysis. The included studies demonstrated that high-quality nursing care significantly improves clinical outcomes and reduces complications in patients receiving ECMO. Effective nursing interventions included prone positioning combined with ECMO for patients with acute respiratory distress syndrome, meticulous infection control, comprehensive and continuous nursing protocols, skilled nursing, and multidisciplinary management. These interventions have been shown to improve oxygenation, reduce complications, such as bleeding, manage blood pressure, and enhance overall clinical outcomes. Conclusion : High-quality nursing interventions are critical to improve survival and reduce complications in patients receiving ECMO. Implementing a multidisciplinary approach and comprehensive nursing protocols, including infection control and psychological support, is essential for the effective management of these patients. The findings of this study provide a foundation for the development of practical guidelines and educational programs to improve the quality of care for patients undergoing ECMO, ultimately enhancing the effectiveness of ECMO treatment and patient outcomes.

• Journal of Periodontal and Implant Science
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• 제53권1호
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• pp.2-19
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• 2023

Purpose: Surgical techniques in orthodontics have received widespread attention in recent years. Meanwhile, biomaterials with high molecular content have been introduced, such as platelet concentrates (PCs), which may accelerate orthodontic tooth movement (OTM) and reduce periodontal damage. The present systematic review aimed to answer the following PICO question: "In patients in whom orthodontic surgical techniques are performed (P), what is the effectiveness of using PCs over the surgical site (I) when compared to not placing PCs (C) to achieve faster tooth movement (O)?" Methods: A search was performed in 6 databases. The criteria employed were those described in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses declaration. The present review included studies with a control group that provided information about the influence of PCs on the rate of OTM. Results: The electronic search identified 10 studies that met the established criteria. Conclusions: The included studies were very diverse, making it difficult to draw convincing conclusions. However, a tendency was observed for OTM to be accelerated when PCs were used as an adjuvant for canine distalization after premolar extraction when distalization was started in the same session. Likewise, studies seem to indicate an association between PC injection and the amount of canine retraction. However, it is not possible to affirm that the use of PCs in corticotomy shortens the overall treatment time, as this question has not been studied adequately.

• 한국산학기술학회논문지
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• 제13권1호
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• pp.370-381
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• 2012

다기준 의사결정 연구는 평가기준이 상이한 다수의 선호도로부터 최선의 대안을 찾는 방법으로 실시간 재난 탐지, 센서를 이용한 서식 모니터링 등의 응용환경에서 활용되어 왔다. 최근 유효시간 데이터 스트림 응용환경에서 각 객체들이 개개의 유효시간을 가지므로, 기존의 슬라이딩 윈도우보다 다기준 의사결정 방법, 즉 스카이라인 질의 수행에 더 많은 연산이 필요한다. 본 연구에서는 유효시간 데이터 스트림에서 스카이라인 질의를 수행하는 TI-Sky 알고리즘을 제시한다. 실시간 환경에서 새로운 객체가 생성되고 소멸되기까지 유효한 객체들을 관리하고 스카이라인 질의를 수행하기 위해 파티션단위의 시간 지배관계를 제시한다. 객체의 생성과 유효시간, 지배관계에 따라 시간지배관계를 갱신하며 다양한 방법으로 사멸객체를 제거하여 수행성능을 향상 시켰다. 실험을 통해 TI-Sky가 다양한 데이터 상에서 기존 연구보다 뛰어난 성능으로 스카이라인 질의를 수행하는 것을 증명하였다.

• 디지털융복합연구
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• 제16권7호
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• pp.249-257
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• 2018

본 논문은 신기술이 융합된 도로안전시설물에 대한 평가기준 탐색 및 평가를 위한 가상현실 시뮬레이션 환경 구축을 목적으로 하였다. 가상현실 시뮬레이션을 위해서는 높은 현실감과 정확한 행동 데이터 추출이 필요하다. 이를 위해 Unreal Engine을 활용하여 주변 환경을 외부환경과 차량환경으로 나눠 제작하였다. 외부환경은 주변 환경, 날씨, 시간대, 타 차량으로 나눠 제작하였으며 차량환경은 승용차와 화물차를 요인으로 제작하였다. 이후, 발광 도로표지병에 대한 샘플 시뮬레이션 제작 및 사전실험을 진행하여, 도로표지병이 5m 간격이 10m 간격보다 더 차선유도를 잘한다는 결과를 나타냈다. 이는 차후 새로운 기술이 접목된 새로운 도로안전시설물에 대한 평가기준에 대한 탐색을 위한 시뮬레이션 작성에서도 활용 가능하다는 것을 확인할 수 있었다. 향후, 다른 도로시설물에 대한 모델링 및 샘플 컴포넌트를 추가하여 다양한 환경에 대한 시뮬레이션이 가능하도록 할 수 있을 것이다.