• The Journal of Korean Physical Therapy
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• 제19권4호
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• pp.1-14
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• 2007

Background: It is generally accepted that skeletal muscle contraction is triggered by nerve impulse and intracellular $Ca^{2+}\;([Ca^{2+}]_i)$ released from intracellular $Ca^{2+}$ stores such as sarcoplasmic reticulum (SR). Specifically, this process, called excitation-contraction (E-C) coupling, takes place at intracellular junctions between the plasma membrane, the transverse (T) tubule L-type $Ca^{2+}$ channel (dihydropyridine-sensitive L-rype $Ca^{2+}$ channel, DHPR, also called tetrads), and the SR $Ca^{2+}$ release channel (ryanodine-sensitive $Ca^{2+}$ release channel, RyR, also called feet) of internal $Ca^{2+}$ stores in skeletal muscle cells. Furthermore, it has been reported that the $Ca^{2+-}$ dependent and -independent contraction determine the expression of skeletal muscle genes, thus providing a mechanism for tightly coupling the extent of muscle contraction to regulation of muscle plasticity-related excitation-transcription (E-T) coupling. Purpose: Expression and activity of plasticity-associated enzymes in gastrocnemius muscle strips have not been well studied, however. Methods: Therefore, in this study the expression and phosphorylation of E-C and E-T coupling-related mediators such as protein kinases, ROS(reactive oxygen species)- and apoptosis-related substances, and others in gastrocnemius muscles from rats was examined. Results: I found that expression and activity of MAPKs (mitogen-activated protein kinases, ERK1/2, p38MAPK, and SAPK/JNK), apoptotic proteins (cleaved caspase-3, cytochrome c, Ref-1, Bad), small GTP-binding proteins (RhoA and Cdc42), actin-binding protein (cofilin), PKC (protein kinase C) and $Ca^{2+}$ channel (transient receptor potential channel 6, TRPC6) was observed in rat gastrocnemius muscle strips. Conclusion: These results suggest that MAPKs, ROS- and apoptosis-related enzymes, cytoskeleton-regulated proteins, and $Ca^{2+}$ channel may in part functionally import in E-C and E-T coupling from rat skeletal muscles.

• 한국기계가공학회지
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• 제12권5호
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• pp.57-66
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• 2013

This study investigates structural and vibration analyses due to the change of bolt Numbers on models 1 and 2 of flange couplings connected with both sides of axis. As maximum equivalent stresses of models 1 and 2 are 122.05 and 102.3 MPa respectively by the basis of bolt, these stresses are within the allowable stress of this model and the safety of bolt design is verified. As maximum equivalent stresses of models 1 and 2 are 196.2 and 196.4 MPa respectively by the basis of body, these stresses are within the allowable stress of this model and the safety of body design is verified. Through natural frequency analysis, maximum displacements of model 1 and 2 are shown at the frequencies of 6565.1 and 6614.9 Hz respectively. Maximum displacements in cases of models 1 and 2 are shown at harmonic frequencies of 7760 and 7840 Hz at real loading conditions. By putting these study results together, the durability of vibration at model 2 with bolt numbers of 8 becomes better than model 1 with bolt numbers of 6. These study results can be effectively utilized with the design on flange coupling by anticipating and investigating prevention and durability against its damage.

• 대한기계학회논문집A
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• 제31권1호
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• pp.77-88
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• 2007

Axiomatic Design has been developed as a general design framework during past two decades and TRIZ has been developed for a design tool over 50 years. Axiomatic design is quite excellent in that design should be decoupled. When a design matrix is established, the characteristics of the design are identified according to the coupling properties. If the design is coupled, a decoupling process should be found. However, axiomatic design does not specifically indicate how to decouple a coupled design. In this research, the coupling manner is classified into six patterns. Each pattern could be solved by an appropriate TRIZ module. A table, which matches the coupling pattern and a TRIZ module, is proposed for effective application of the two design theories. The decoupling ideas are proposed by using TRIZ modules. When the number of decoupled designs is more than one, the engineer should select the final idea. The proposed method is applied to practical cases such as a tape feeder and a beam adjuster of the laser marker.

• 한국기계가공학회지
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• 제16권1호
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• pp.70-76
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• 2017

The pollution problem of fossil energy sources has caused the development of green energy harvesting systems. Piezoelectric energy harvesting technology has been developed under those external environmental factors. A piezoelectric energy harvester can be defined as a device which transforms mechanical vibration or impact energy into electrical energy. Most researches have focused on bender structures. However, these have a limitation on energy efficiency because of the small effective electromechanical coupling factor, around 10%. Therefore, we should look for a new design for energy harvesting. A cymbal energy harvester can be a good candidate for the high-power energy harvester because it uses a high amplification mechanism using endcaps while keeping a higher electromechanical coupling factor. In this research, we focused on energy efficiency improvements of the cymbal energy harvester by changing the polarization direction, because the electromechanical coupling factor of the k33 mode and the k15 mode is larger than that of the k31 mode. Theoretically, we checked the cymbal harvester with radial polarization and it could obtain 6 times larger energy than that with the k31 direction polarization. Furthermore, we verified the theoretical expectation using the finite element method program. Consequently, we could expect a more efficient cymbal harvester with the radial polarization by comparing two polarization directions.

• Bulletin of the Korean Chemical Society
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• 제28권11호
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• pp.2025-2028
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• 2007

Homogeneous zinc tetrahalide complexes, highly active catalysts for the coupling reactions of alkylene oxide and CO2 produce alkylene carbonates, were heterogenized due to their tendency to decompose produced alkylene carbonates during the distillation process. Heterogenization of homogeneous zinc tetrahalide complexes was achieved by polymerizing 1-alkyl-3-vinylimidazolium zinc tetrahalides. These polymerized zinc tetrahalide catalysts displayed similar activities to their corresponding monomeric analogues for the coupling reactions of carbon dioxide with ethylene oxide (EO) or propylene oxide (PO) to produce ethylene carbonate (EC) or propylene carbonate (PC). TGA studies showed that the polymer-supported zinc tetrahalide catalysts are thermally stable up to 320 oC. The catalyst recycle test showed that the supported catalysts could be reused over six times. After removal of the polymer-supported catalyst through a simple filtration, EC was able to be isolated without decomposition.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1993년도 하계학술대회 논문집 B
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• pp.581-583
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• 1993

One of the principal problems encountered in the use of fiber reinforced composites is to establish an active fiber surface to achieve maximum adhesion between resin and fiber surface. In order to improve the interface bonding, the surface of glass fiber should be treated with silane coupling agent in ordinary composite manufacturing processes. However, the price of the coupling agent is very high and in the treating process voids are formed, which decreasees electrical and mechanical strength. We want to develope new process that will overcome the disadvantage of the coupling agent and achieve maximum adhesion at the interface between resin and fiber by active plasma treatment on the glass fiber surface. In this study, we investigate the improvement of contact angle on the glass plate surface as the first step in developing new GFRP.

• Journal of Welding and Joining
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• 제9권3호
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• pp.41-51
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• 1991

The thermomechanical coupling phenomena in the resistance welding process is complicated due to interactions of mechanical, thermal and electrical factors. Although experimental investigations of resistance spot welding have been carried out, but there are a few by computer simulation. so the purpose of this research is to decrease the time and cost much required in experimental investigation by carrying out the analysis of the resistance spot welding process through computer simulation based on the finite element method. The tool used in the computer simulation is the commercial ANSYS program package. A two dimensional axisymetric model is used to simulate the resistance spot welding for two stainless steel sheets of equal thickness and parametric study is carried out for variable welding current, workpieces of unequal thickness and dissimilar materials. The results from the computer simulation are in good agreement with the experimental one. Through these results, such items as stress distribution, temperature profiles, thermal expansion and weld nugget formation are predicted. Reliability and applicability of finite element models have been demonstrated to simulate and to analyze the resistance spot welding process.

• 한국전자거래학회지
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• 제12권2호
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• pp.75-93
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• 2007

최근 서비스지향 아키텍처(SOA, Service-Oriented Architecture)가 IT 인프라의 복잡성 및 유지비용을 최소화하고, 기업의 생산성과 유연성을 극대화 할 수 있는 새로운 IT전략으로 대두되고 있다. SOA는 느슨한 연결(Loosely coupling)을 통해 융통성을 증가시키고, 서비스 공급자, 서비스 요청자, 서비스 저장소라는 세 요소가 유기적으로 연계되어 있는 특징을 갖는다. 이는 SOA를 구현하는데 있어 기존의 개발 방법론의 적용을 어렵게 한다. 본 논문에서는 서비스 공급자와 서비스 요청자의 관점을 반영하여, SOA를 위한 서비스 지향 개발 프로세스를 제안한다. 6개의 단계를 가진 전체 프로세스는 개발 계획 수립 활동을 통해 목적에 따라 프로세스 유형을 선택할 수 있다.

• Membrane and Water Treatment
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• 제3권1호
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• pp.1-23
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• 2012

The coupling of anaerobic biological process and membrane separation could provide excellent suspended solids removal and better biomass retention for wastewater treatment. This coupling improves the biological treatment process while allowing for the recovery of energy through biogas. This review gives a basic description of the anaerobic wastewater treatment process, summarizes the state of the art of anaerobic membrane bioreactors (AnMBRs), and describes the current research trends and needs for the development of AnMBRs. The research interest on AnMBR has grown over the conventional anaerobic processes such as upflow anaerobic sludge blanket (UASB). Studies on AnMBRs have developed different reactor configurations to enhance performances. The AnMBR performances have achieved comparable status to other high rate anaerobic reactors. AnMBR is highly suitable for application with thermophilic anaerobic process to enhance performances. Studies indicate that the applications of AnMBR are not only limited to the high strength industrial wastewater treatment, but also for the municipal wastewater treatment. In recent years, there is a significant progress in the membrane fouling studies, which is a major concern in AnMBR application.

• 소음진동
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• 제11권1호
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• pp.132-140
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• 2001

The vibratory gyroscope can effectively measure the angular velocity as the oscillating and position-sensing mode are exactly tuned. The veering Phenomenon impedes the exact tuning, which is caused by the mode coupling of two modes. In this paper, the gyroscope's structure with two frames is introduced to minimize the veering phenomenon that destabilizes the tuning process of oscillating and position-sensing mode. Experimental results show that the Proposed structure can achieve the mode intersection without veering phenomenon.