• Journal of Ginseng Research
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• v.37 no.1
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• pp.64-73
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• 2013

Korean red ginseng water extract (KG-WE) has known beneficial effects on the cardiovascular system via inducting nitric oxide (NO) production in endothelium. Endothelial arginase inhibits the activity of endothelial nitric oxide synthase (eNOS) by substrate depletion, thereby reducing NO bioavailability and contributing to vascular diseases including hypertension, aging, and atherosclerosis. In the present study, we demonstrate that KG-WE inhibits arginase activity and negatively regulates NO production and reactive oxygen species generation in endothelium. This is associated with increased dimerization of eNOS without affecting the protein expression levels of either arginase or eNOS. In a vascular tension assay, when aortas isolated from wild type mice were incubated with KG-WE, NO-dependent enhanced vasorelaxation was observed. Furthermore, KG-WE administered via by drinking water to atherogenic model mice being fed high cholesterol diet improved impaired vascular function. Taken together, these results suggest that KG-WE may exert vasoprotective effects through augmentation of NO signaling by inhibiting arginase. Therefore, KG-WE may be useful in the treatment of vascular diseases derived from endothelial dysfunction, such as atherosclerosis.

• Journal of the Korean Wood Science and Technology
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• v.39 no.2
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• pp.117-124
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• 2011

The possibility of using the properties of an ultrasonic wave as a means for monitoring the moisture content of a board during drying was investigated. The ultrasonic wave signals are influenced by moisture content and other factors such as temperature, moisture gradient and coupling area. The effect of temperature was examined by measuring the transit times, amplitudes and velocities of ultrasonic waves transmitted through air, a metal bar and a board at various temperatures. The effect of a moisture gradient was studied using a model specimen composing five wood pieces of various moisture contents. The velocity and amplitude of the ultrasonic waves transmitted through air increase with temperature, while those through a metal bar and a board decrease. It was confirmed that the temperature effect is partially attributed to the change of transducer's properties. The effect of a moisture gradient on the velocity of an ultrasonic wave varies with the average moisture content of a board. As the dimension of the end face of a board increases the velocity of an ultrasonic wave increases and low frequency components more dominates than high frequency components. The transit times of ultrasonic waves transmitted through a board during kiln drying reflect the temperature steps in the drying schedule and the transducer temperatures.

• Steel and Composite Structures
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• v.13 no.1
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• pp.71-89
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• 2012

The paper investigates beam lateral buckling stability according to linear and non-linear models. Closed form solutions for single-symmetric cross sections are first derived according to a non-linear model considering flexural-torsional coupling and pre-buckling deformation effects. The closed form solutions are compared to a beam finite element developed in large torsion. Effects of pre-buckling deflection and gradient moment on beam stability are not well known in the literature. The strength of singly symmetric I-beams under gradient moments is particularly investigated. Beams with T and I cross-sections are considered in the study. It is concluded that pre-buckling deflections effects are important for I-section with large flanges and analytical solutions are possible. For beams with T-sections, lateral buckling resistance depends not only on pre-buckling deflection but also on cross section shape, load distribution and buckling modes. Effects of pre-buckling deflections are important only when the largest flange is under compressive stresses and positive gradient moments. For negative gradient moments, all available solutions fail and overestimate the beam strength. Numerical solutions are more powerful. Other load cases are investigated as the stability of continuous beams. Under arbitrary loads, all available solutions fail, and recourse to finite element simulation is more efficient.

• Bulletin of the Korean Chemical Society
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• v.35 no.11
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• pp.3244-3248
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• 2014

Two ethylenediamine cobalt(II) oxalate complexes Co(ox)(en), 1 and $Co(ox)(en){\cdot}2H_2O$, 2 have been hydrothermally synthesized and characterized by single crystal X-ray diffraction, IR spectrum, TG analysis, and magnetic measurements. In 1, Co atoms are coordinated by two bis-bidentate oxalate ions in transconfiguration to form Co(ox) chains, which are further bridged by ethylenediamine molecules to produce 2D grid layers, Co(ox)(en). In 2, Co atoms are coordinated by bridging oxalate ions in cis-configuration to form Co(ox) chains, and the additional chelation of ethylenediamine to Co atoms completes 1D zigzag chain, Co(en)(ox). Two lattice water molecules stabilize the chains through hydrogen bonding. Magnetic susceptibility measurements indicate that both complexes exhibit weak antiferromagnetic coupling between cobalt(II) ions with the susceptibility maxima at 23 K for 1 and 20 K for 2, respectively. In 1 and 2, the oxalate ligands afford a much shorter and more effective pathway for the magnetic interaction between cobalt ions compared to the ethylenediamine ligands, so the magnetic behaviors of both complexes could be well described with 1D infinite magnetic chain model.

• The Transactions of the Korean Institute of Power Electronics
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• v.6 no.4
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• pp.317-324
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• 2001

This paper proposes a SSSC based on 3-level half-bridge inverters. The dynamic characteristic of the proposed SSSC was analyzed by EMTP simulation and a scaled hardware model, assuming that the SSSC is inserted in the transmission line of the one-machine-infinite-but power system. The proposed SSC has six 3-level half-bridge inverters per phase, which operates in PWM mode. The proposed SSSC generates a quasi-sinusoidal output voltage by 90 degree phase shift to the line current. The proposed SSSC does not require the coupling transformer for voltage injection, and has a flexibility in operation voltage by increasing the number of series connection.

• Journal of the Korean Institute of Intelligent Systems
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• v.14 no.6
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• pp.693-698
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• 2004

In this paper, an iterative learning control method is applied to suppress a vibration of a 2-mass system which has a flexible coupling between a load and a motor. More specifically, conditions for the load speed without vibration are derived based on the steady-state condition. And the desired motor position trajectory is synthesized based on the relation between the load and motor speed. Finally, a PD-type iterative learning control law is applied for the desired motor position trajectory. Since the learning law applied for the desired trajectory guarantees the perfect tracking performance, the resulting load speed shows no vibration even when there exist model uncertainties. A modification to the learning law is also Presented to suppress undesired effects of an initial position error, The simulation results show the effectiveness of the proposed learning method.

• 한국전산유체공학회:학술대회논문집
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• 1995.10a
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• pp.160-168
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• 1995

This paper describes computational efforts on the various energy and environmental problems using Patankar's SIMPLE method. The specific problems included in this study are : pollutant and flammable material dispersions in open and confined areas, aerator-induced flow in a lake for DO(dissolved oxygen) concentration, primary clarifier for water and waste water treatment, hood ventilation in workplace, cyclone and LNG combustors and Dow chlorination reactor. A control-volume based finite-difference method is employed together with the power-law scheme. The pressure-velocity coupling is resolved by the use of the revised version of SIMPLE, says SIMPLER and SIMPLEC. The Reynolds stresses are closed using the standard or the RNG $k-{\varepsilon}$ models. Turbulent reaction is modeled using two fast chemistry methods such as eddy breakup and conserved scalar models. Further, a nonequilibrium model is developed for the application of the chlorination process in the Dow reactor. Other important empirical models and physical insights appeared in this study are presented and discussed in a brief note. The computational method developed in this study is considered, in general, as a viable tool for the design and determination of the optimal condition of various engineering system of interest.

• 한국전산유체공학회:학술대회논문집
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• 2008.03a
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• pp.186-196
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• 2008

The dependence of the rheological properties of blood on shape, aggregation, and deformability of red blood cells (RBCs) has been investigated using hybrid systems by coupling fluid with solid models. We present a simple approach for simulating blood as a multi-component fluid, in which RBCs are modeled as droplets of acquired biconcave shape. We used lattice Boltzmann method (LBM) due to its excellent numerical stability as a simulation tool. The model enables us to control the droplet static shape by imposing non-isotropic surface tension force on the interface between the two components. The use of the proposed non-isotropic surface tension method is justified by the Norris hypothesis. This hypothesis states that the shape of the RBC is due to a non-uniform interfacial surface tension force acting on the RBC periphery. This force is caused by the unbalanced distribution of the lipid molecules on the surface of the RBC. We also used the same concept to investigate the dynamic shape change of the RBC while flowing through the microvasculature, and to explore the physics of the Fahraeus, and the Fahraeus-Lindqvist effects.

• Journal of computational fluids engineering
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• v.2 no.1
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• pp.93-108
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• 1997

This paper describes several computational results on the various energy and environmental problems using Patankar's SIMPLE method. The specific problems included in this study are : pollutant and flammable material dispersions in open and confined areas, buoyancy-driven flow in a lake, primary clarifier for water and waste water treatment, hood ventilation in workplace. cyclone combustor and Dow chlorination reactor. A control-volume based finite-difference method is employed together with the power-law scheme. The pressure-velocity coupling is resolved by the use of the revised version of SIMPLE, says SIMPLER and SIMPLEC. The Reynolds stresses are closed using the standard or RNG κ-ε models. A nonequilibrium turbulent reaction model is developed for the application of the chlorination process in the Dow thermal reactor. Other important empirical models and physical insights appeared in this study are presented and discussed in a brief note. The computational method developed in this study is considered, in general, as a viable tool for the design and determination of the optimal operating condition of various environmental engineering system of interest.

• 한국전산유체공학회:학술대회논문집
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• 2008.10a
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• pp.186-196
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• 2008

The dependence of the rheological properties of blood on shape, aggregation, and deformability of red blood cells (RBCs) has been investigated using hybrid systems by coupling fluid with solid models. We present a simple approach for simulating blood as a multi-component fluid, in which RBCs are modeled as droplets of acquired biconcave shape. We used lattice Boltzmann method (LBM) due to its excellent numerical stability as a simulation tool. The model enables us to control the droplet static shape by imposing non-isotropic surface tension force on the interface between the two components. The use of the proposed non-isotropic surface tension method is justified by the Norris hypothesis. This hypothesis states that the shape of the RBC is due to a non-uniform interfacial surface tension force acting on the RBC periphery. This force is caused by the unbalanced distribution of the lipid molecules on the surface of the RBC. We also used the same concept to investigate the dynamic shape change of the RBC while flowing through the microvasculature, and to explore the physics of the Fahraeus, and the Fahraeus-Lindqvist effects.