• 제목/요약/키워드: coupled response

검색결과 996건 처리시간 0.024초

경극과 가부키의 공연공간과 연출양식의 비교 연구 (A Comparative Study on the Performance Stage and Performing Style between Peking Opera and Kabuki.)

  • 오경희
    • 비교문화연구
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    • 제31권
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    • pp.35-64
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    • 2013
  • This thesis seeks to compare China's Jing-ju and Japan's Kabuki for their common aspects and differences and examine how they are performed on the stage. Jing-ju is often called as Beijing Opera to refer to a musical play completed during the mid-Ching era and developed around Beijing. Jing-ju is composite arts of music, dance and play which are remarkable in its strict patterns in move along with luxurious costume and heavy make-up. Kabuki which was developed during the Edo-period, is expressional arts also structured with music, dance and play coupled with extravagant costume as well as even more strictly controlled move and emphasis on the beauty of form. The two plays seem very similar to each other in their time setting to gain popularity or features of play. It may look obvious that Jing-ju which had developed earlier than Kabuki, affected the latter's formation. However, general social practices or cultural trends in China and Japan at the time of their development also influenced literature and arts thus affecting play contents and performance expressions. Although the two plays have similar stage structure, they developed in different ways with detailed differences and actors' performance on the stage, way of using a stage and other ways of directing play are largely distinctive from each other. If a play's primary goal is to gain recognition of audience and draw their positive response, the relationship between play and stage becomes essential. With this understanding, this thesis aims to identify where such similarities and differences between the two plays are from by comparing historical background, stage structural development and directing manner development at a basic level.

모튼이펙트 해석을 위한 동역학-구조-유체-열전달 시간과도응답 연성해석 시차적분법에서 시상수 효과 분석 (Analysis of Integration Factor Effect in Dynamic-Structure-Fluid-Heat Coupled Time Transient Staggered Integration Scheme for Morton Effect Analysis)

  • 서준호;정승화
    • Tribology and Lubricants
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    • 제35권1호
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    • pp.77-86
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    • 2019
  • The present study focuses on the effect of staggered integration factor (SIF) on Morton effect simulation results. The Morton effect is a synchronous rotordynamic instability problem caused by the temperature differential across the journal in fluid film bearings. Convection and conduction of heat in the thin film displaces the hot spot, which is the hottest circumferential position in the thin film, from -20 to 40 degrees ahead of the high spot, where the minimum film clearance is experienced. The temperature differential across the journal causes a bending moment and the corresponding thermal bow in the rotating frame acts like a distributed synchronous excitation in the fixed frame. This thermal bow may cause increased vibrations and continued growth of the synchronous orbit into a limit cycle. The SIF is developed assuming that the response of the rotor-lubricant-bearing dynamic system is much quicker than that of the bearing-journal thermal system, and it is defined as the ratio between the simulation time of the thermal system and the rotor-spinning period. The use of the SIF is unavoidable for efficient computing. The value of the SIF is chosen empirically by the software users as a value between 100 and 400. However, the effect of the SIF on Morton effect simulation results has not been investigated. This research produces simulation results with different values of SIF.

Suppression of Foxo3-Gatm by miR-132-3p Accelerates Cyst Formation by Up-Regulating ROS in Autosomal Dominant Polycystic Kidney Disease

  • Choi, Seonju;Kim, Do Yeon;Ahn, Yejin;Lee, Eun Ji;Park, Jong Hoon
    • Biomolecules & Therapeutics
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    • 제29권3호
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    • pp.311-320
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    • 2021
  • Accumulation of reactive oxygen species (ROS) is associated with the development of various diseases. However, the molecular mechanisms underlying oxidative stress that lead to such diseases like autosomal dominant polycystic kidney disease (ADPKD) remain unclear. Here, we observed that oxidative stress markers were increased in Pkd1f/f:HoxB7-Cre mice. Forkhead transcription factors of the O class (FOXOs) are known key regulators of the oxidative stress response, which have been observed with the expression of FoxO3a in an ADPKD mouse model in the present study. An integrated analysis of two datasets for differentially expressed miRNA, such as miRNA sequencing analysis of Pkd1 conditional knockout mice and microarray analysis of samples from ADPKD patients, showed that miR-132-3p was a key regulator of FOXO3a in ADPKD. miR-132-3p was significantly upregulated in ADPKD which directly targeted FOXO3 in both mouse and human cell lines. Interestingly, the mitochondrial gene Gatm was downregulated in ADPKD which led to a decreased inhibition of Foxo3. Overexpression of miR-132-3p coupled with knockdown of Foxo3 and Gatm increased ROS and accelerated cyst formation in 3D culture. This study reveals a novel mechanism involving miR-132-3p, Foxo3, and Gatm that is associated with the oxidative stress that occurs during cystogenesis in ADPKD.

기록관리 관점에서 본 코로나 19 관련 개인정보 이슈와 대응방안 (COVID-19 Related Personal Information Issues and Countermeasures from the Perspective of Record Management)

  • 정지혜;나정호;장지혜;오효정
    • 정보관리학회지
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    • 제37권4호
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    • pp.81-107
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    • 2020
  • 최근 우리나라를 비롯해 전 세계가 '코로나19'라는 초유의 사태를 맞이한 이때, 감염병 확산을 막기 위해 적극적으로 정보를 '공개'하는 관점과 이러한 사회적 조치가 개인의 기본권 침해와 맞물리게 되면서 개인정보를 '보호'해야 하는 관점이 상충되고 있다. 이에 본 연구에서는 감염병 위기에 따른 국가의 대응 상황을 파악하기 위해 감염병 대응 표준매뉴얼을 바탕으로 위기경보 단계별 생산되는 공공기록물을 살펴보았으며, 특히 개인정보가 포함된 기록물의 유형과 공개 현황을 분석하였다. 이를 통해 위기경계단계에 따라 공공기관 차원에서 수집되는 개인정보 뿐 아니라 민간에서 수집, 관리해야 할 개인정보 범위가 결정됨을 파악하였으며, 이에 대한 일반인의 인식을 파악하기 위해 뉴스미디어에 보도된 개인정보 관련 주요 이슈를 분석하였다. 이를 통해 도출된 개인정보를 포함한 기록 관리의 주요 쟁점과 문제점에 대해 고찰하고 이에 대한 개선점을 수집 및 관리, 폐기의 기록의 생애주기 관점에서 제안하였다.

Potential of watermelon (Citrullus lanatus) to maintain oxidative stability of rooster semen for artificial insemination

  • Jimoh, Olatunji Abubakar;Akinola, Micheal Olawale;Oyeyemi, Bolaji Fatai;Oyeyemi, Wahab Adekunle;Ayodele, Simeon Olugbenga;Omoniyi, Idowu Samuel;Okin-Aminu, Hafsat Ololade
    • Journal of Animal Science and Technology
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    • 제63권1호
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    • pp.46-57
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    • 2021
  • Fruits with antioxidant enrichment can be an economically affordable supplement for mitigating oxidative damage prone spermatozoa membrane pathologies. Computer-assisted sperm analyzer and oxidative status were utilized to evaluate the impact of watermelon (Citrullus lanatus) fortification of dextrose saline as diluent for rooster semen and fertility response of hens inseminated. Watermelon juice and dextrose saline were used to formulate diluent of 7 treatments consisting of unextended semen (positive control), 10%, 20%, 30%, 40%, 50% and only dextrose saline (negative control) designated as Treatments 1-7. Pooled semen was obtained from fertile roosters and equilibrated with diluents at ratio 1:2 in the various treatments and were evaluated using computer software coupled microscope and seminal oxidative status assay. 168 laying hens randomly divided into 7 treatment of 8 replicates and 3 hen per replicate. Hen were everted, and semen (2 × 108 Spermatozoa) deposited intra-vagina and eggs collected over 8 weeks to assess fertility and hatchability of eggs laid. The result obtained revealed that watermelon-dextrose saline rooster semen diluent enhanced progressive motility, sperm kinetics and lowered non-progressive motility in T2-T6 compared to T7 over the 3 hours of evaluation. Watermelon addition to rooster semen diluent enhance the antioxidant capacity of rooster semen and lowered lipid peroxide generation. The percentage fertility was highest in T3 (81.01%) and T4 (81.24%) with lowest value obtained in T7 (73.46%). The hatchability of eggs set of hens inseminated with undiluted semen (71.46%) was lower than values for hens inseminated with watermelon inclusive extended semen (75.71%-80.39%). The optimal inclusion of 30%-40% watermelon in dextrose saline diluent enhance rooster semen kinetics, seminal oxidative stability and egg fertility.

Specialized Proresolving Mediators for Therapeutic Interventions Targeting Metabolic and Inflammatory Disorders

  • Han, Yong-Hyun;Lee, Kyeongjin;Saha, Abhirup;Han, Juhyeong;Choi, Haena;Noh, Minsoo;Lee, Yun-Hee;Lee, Mi-Ock
    • Biomolecules & Therapeutics
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    • 제29권5호
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    • pp.455-464
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    • 2021
  • Uncontrolled inflammation is considered the pathophysiological basis of many prevalent metabolic disorders, such as nonalcoholic fatty liver disease, diabetes, obesity, and neurodegenerative diseases. The inflammatory response is a self-limiting process that produces a superfamily of chemical mediators, called specialized proresolving mediators (SPMs). SPMs include the ω-3-derived family of molecules, such as resolvins, protectins, and maresins, as well as arachidonic acid-derived (ω-6) lipoxins that stimulate and promote resolution of inflammation, clearance of microbes, and alleviation of pain and promote tissue regeneration via novel mechanisms. SPMs function by binding and activating G protein-coupled receptors, such as FPR2/ALX, GPR32, and ERV1, and nuclear orphan receptors, such as RORα. Recently, several studies reported that SPMs have the potential to attenuate lipid metabolism disorders. However, the understanding of pharmacological aspects of SPMs, including tissue-specific biosynthesis, and specific SPM receptors and signaling pathways, is currently limited. Here, we summarize recent advances in the role of SPMs in resolution of inflammatory diseases with metabolic disorders, such as nonalcoholic fatty liver disease and obesity, obtained from preclinical animal studies. In addition, the known SPM receptors and their intracellular signaling are reviewed as targets of resolution of inflammation, and the currently available information on the therapeutic effects of major SPMs for metabolic disorders is summarized.

Power control of CiADS core with the intensity of the proton beam

  • Yin, Kai;Ma, Wenjing;Cui, Wenjuan;He, Zhiyong;Li, Xinxin;Dang, Shiwu;Yang, Feng;Guo, Yuhui;Duan, Limin;Li, Meng;Hou, Yikai
    • Nuclear Engineering and Technology
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    • 제54권4호
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    • pp.1253-1260
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    • 2022
  • This paper reports the control method for the core power of the China initiative Accelerator Driven System (CiADS) facility. In the CiADS facility, an intense external neutron source provided by a proton accelerator coupled to a spallation target is used to drive a sub-critical reactor. Without any control rod inside the sub-critical reactor, the core power is controlled by adjusting the proton beam intensity. In order to continuously change the beam intensity, an adjustable aperture is considered to be used at the Low Energy Beam Transport (LEBT) line of the accelerator. The aperture size is adjusted based on the Proportional Integral Derivative (PID) controllers, by comparing either the setting beam intensity or the setting core power with the measured value. To evaluate the proposed control method, a CiADS core model is built based on the point reactor kinetics model with six delayed neutron groups. The simulations based on the CiADS core model have indicated that the core power can be controlled stably by adjusting the aperture size. The response time in the adjustment of the core power depends mainly on the adjustment time of the beam intensity.

Elicitation of Innate Immunity by a Bacterial Volatile 2-Nonanone at Levels below Detection Limit in Tomato Rhizosphere

  • Riu, Myoungjoo;Kim, Man Su;Choi, Soo-Keun;Oh, Sang-Keun;Ryu, Choong-Min
    • Molecules and Cells
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    • 제45권7호
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    • pp.502-511
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    • 2022
  • Bacterial volatile compounds (BVCs) exert beneficial effects on plant protection both directly and indirectly. Although BVCs have been detected in vitro, their detection in situ remains challenging. The purpose of this study was to investigate the possibility of BVCs detection under in situ condition and estimate the potentials of in situ BVC to plants at below detection limit. We developed a method for detecting BVCs released by the soil bacteria Bacillus velezensis strain GB03 and Streptomyces griseus strain S4-7 in situ using solid-phase microextraction coupled with gas chromatography-mass spectrometry (SPME-GC-MS). Additionally, we evaluated the BVC detection limit in the rhizosphere and induction of systemic immune response in tomato plants grown in the greenhouse. Two signature BVCs, 2-nonanone and caryolan-1-ol, of GB03 and S4-7 respectively were successfully detected using the soil-vial system. However, these BVCs could not be detected in the rhizosphere pretreated with strains GB03 and S4-7. The detection limit of 2-nonanone in the tomato rhizosphere was 1 µM. Unexpectedly, drench application of 2-nonanone at 10 nM concentration, which is below its detection limit, protected tomato seedlings against Pseudomonas syringae pv. tomato. Our finding highlights that BVCs, including 2-nonanone, released by a soil bacterium are functional even when present at a concentration below the detection limit of SPME-GC-MS.

Flexural response of steel beams strengthened by fibre-reinforced plastic plate and fire retardant coating at elevated temperatures

  • Ahmed, Alim Al Ayub;Kharnoob, Majid M.;Akhmadeev, Ravil;Sevbitov, Andrei;Jalil, Abduladheem Turki;Kadhim, Mustafa M.;Hansh, Zahra J.;Mustafa, Yasser Fakri;Akhmadullina, Irina
    • Structural Engineering and Mechanics
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    • 제83권4호
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    • pp.551-561
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    • 2022
  • In this paper, the effect of fire conditions according to ISO 834 standard on the behavior of carbon fibre-reinforced plastic (CFRP) reinforced steel beams coated with gypsum-based mortar has been investigated numerically. To study the efficiency of these beams, 3D coupled temperature-displacement finite element analyzes have been conducted. Mechanical and thermal characteristics of three different parts of composite beams, i.e., steel, CFRP plate, and fireproof coating, were considered as a function of temperature. The interaction between steel and CFRP plate has been simulated employing the adhesion model. The effect of temperature, CFRP plate reinforcement, and the fireproof coating thickness on the deformation of the beams have been analyzed. The results showed that within the first 120 min of fire exposure, increasing the thickness of the fireproof coating from 1 mm to 10 mm reduced the maximum temperature of the outer surface of the steel beam from 380℃ to 270℃. This increase in the thickness of the fireproof layer decreased the rate of growth in the temperature of the steel beam by approximately 30%. Besides excellent thermal resistance and gypsum-based mortar, the studied fireproof coating method could provide better fire resistance for steel structures and thus can be applied to building materials.

Design and Analysis of a Novel Methanol SOFC Combined System for Marine Applications Toward Future Green Shipping Goals

  • Duong Phan Anh;Ryu Bo Rim;Hokeun Kang
    • 한국항해항만학회지
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    • 제47권2호
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    • pp.106-119
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    • 2023
  • Due to global decarbonization movement and tightening of maritime emissions restrictions, the shipping industry is going to switch to alternative fuels. Among candidates of alternative fuel, methanol is promising for decreasing SOx and CO2 emissions, resulting in minimum climate change and meeting the goal of green shipping. In this study, a novel combined system of direct methanol solid oxide fuel cells (SOFC), proton exchange membrane fuel cells (PEMFC), gas turbine (GT), and organic Rankine cycle (ORC) targeted for marine vessels was proposed. The SOFC is the main power generator of the system, whereas the GT and PEMFC could recover waste heat from the SOFC to generate useful power and increase waste heat utilizing efficiency of the system. Thermodynamics model of the combined system and each component were established and analyzed. Energy and exergy efficiencies of subsystems and the entire system were estimated with participation of the first and second laws of thermodynamics. The energy and exergy efficiencies of the overall multigeneration system were estimated to be 76.2% and 30.3%, respectively. The combination of GT and PEMFC increased the energy efficiency by 18.91% compared to the SOFC stand-alone system. By changing the methanol distribution ratio from 0.05 to 0.4, energy and exergy efficiencies decreased by 15.49% and 5.41%, respectively. During the starting up and maneuvering period of vessels, a quick response from the power supply system and propulsion plant is necessary. Utilization of PEMFC coupled with SOFC has remarkable meaning and benefits.