• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6169-6179
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• 2015

This study examined the effectiveness of a autonomous regulation improvement smoking cessation program in girls high school students. The study was carried out with a nonequivalent control group pretest-posttest design. The subjects of the present study were 47 girls high school students in G and K city. The subjects were divided into an experimental group (n=23) who participated in the autonomous regulation improvement smoking cessation program, and a control group (n=24) who did not participate. Data were collected from 1 April 2013 through 26 April 2013. Collected data were analyzed using SPSS PC+ 18.0 with the Chi-square test, Fisher' exact test, Mann-Whitney U test, t-test. The experimental group had significantly different in cigarettes smoked per day(p=.044), cotinine in saliva(p=.048), perceived motivation(p=.001) and autonomous regulation(p=.027) in comparison to the control group. The autonomous regulation improvement smoking cessation program, when delivered to girls high school students who smoked, was effective in discouraging the smoking habit, and can be utilized as an effective nursing intervention for girls high school students who smoke.

• Journal of Korean Academy of Nursing
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• v.38 no.2
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• pp.204-216
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• 2008

Purpose: Meta-analysis of this study was to analyze the character of adolescent smoking cessation programs, to calculate the effect size according to variables and to compare the weighted mean effect sizes on adolescent smoking cessation programs in Korea. Methods: Twenty two studies for meta-analysis were selected from dissertations, theses, articles and research papers that had been published from 1995 to 2003. The selected studies had a randomized or nonequivalent control group in a pretest-post test design and had reported statistical value to calculate the effect size. Results: The mean number of sessions was 6.5. The education time per each session varied from 40 to 150 min and the most applied theories were Bandura's social-cognitive theory and the cognitive-behavioral theory. Smoking-knowledge, smoking-attitudes and smoking-amount showed high effects on the first post test after mediating adolescent smoking cessation programs according to the criteria of Cohen. The effect size of urine-cotinine found no homogeneity on the first post test, but it was significantly effective on the second post test. Conclusion: Adolescent smoking cessation programs analyzed in this study were relatively effective in smoking abstinence.

• Journal of Korean Academy of Nursing
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• v.45 no.3
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• pp.347-356
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• 2015

Purpose: In this study, the effectiveness of a motivational interviewing smoking cessation YOU-TURN program for adolescents was examined. The program was based on the self-determination theory. Methods: The study was carried out with a nonequivalent control group pretest-posttest design. Participants in the present study were 136 high school students living in D city. The students were assigned to the experimental group (n=52) who participated in the motivational interviewing smoking cessation YOU-TURN program based on self-determination theory, or to the control group (n=84) who participated in a general smoking cessation program. Data were collected from September 1, 2013 through April 30, 2014. Collected data were analyzed using SPSS PC+ 21.0 with Chi-square test, Fisher's exact test, t-test, Mann-Whitney U test, Repeated Measures ANOVA, and MANOVA-Wilk's Lambda. Results: The experimental group had a significant increase in basic psychological needs, and duration of quitting-smoking in comparison with the control group. The experimental group had a significant decrease in cigarettes smoked per day and cotinine in urine in comparison with the control group. Conclusion: The motivational interviewing YOU-TURN program, when delivered to adolescents who smoked, was effective in discouraging smoking, and can be utilized as an effective nursing intervention for adolescents who smoke.

• Journal of Korean Academy of Nursing
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• v.47 no.2
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• pp.164-177
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• 2017

Purpose: This study was done to develop a strength based I-change smoking cessation program for middle school boys and identified its effects. Methods: The study design was a nonequivalent control group pre-post test design. The participants were 97 middle school students from D city, who were in school from April 6 to September 25, 2015. The experimental group participated in the strength based I-change smoking cessation program, while the comparative group participated in a general smoking cessation program. The control group did not participate in any program. Data analyses involved $x^2$-test, Fishers' exact test, Bonferroni test, and Repeated measures ANOVA, with the IBM SPSS for Windows (version 20.0) program. Results: Compared to the comparison and control groups, the experimental group showed significant improvement in knowledge, attitude, self-efficacy, behavior change. Also cotinine in urine and modeling of social influence in the experimental group significantly decreased after the strength based I-change smoking cessation program. Conclusion: These findings indicate that the strength based I-change smoking cessation program is an effective intervention for middle school boys who smoke. The findings suggest that such programs can be used at public health centers or through school health education to decrease smoking in adolescents.

• Korean Journal of Health Education and Promotion
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• v.24 no.4
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• pp.115-130
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• 2007

Purpose: The Purpose of this study was to investigate the effects of the '5&6 smoking cessation program - six classes in five weeks' on the high school students' perception and smoking behavior. Methods: The data collection was done from November to December, 2006. This study was designed using nonequivalent control group pretest - posttest. Experimental group had 24 students, control group had 41 students. The '5&6 smoking cessation program' was applied to the experimental group for two hours per session during five weeks. Data analysis was done using descriptive statistics, X2-test, Fisher's exact test, Independent-samples t-test, Paired t-test, Cronbach's coefficient alpha. Results: The experimental group showed significant increase on smoking self-efficacy, stage of smoking cessation behavior change and significant decrease on daily smoking amount, dependancy of nicotine, urine cotinine level than control group. But the experimental group was not significantly changed at self-awareness, Pros. for smoking and Cons. for smoking. Conclusion: In conclusion, the results of this study showed that the 5&6 smoking cessation program, which focuses on self-awareness, is effective in adolescent's smoking cessation behaviors.

• Preventive Nutrition and Food Science
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• v.8 no.3
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• pp.289-293
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• 2003

Antioxidant activity and nicotine degradation activity (NDA) of 21 medicinal herbs were determined by using a 1,1-diphenol-2-picrylhydrazyl (DPPH) method and a PLC/PRF5 human liver cell line method, respectively, to develop an anti-smoking aid. The highest and lowest antioxidant activities represented by $IC_{50}$/ value were 30 $\mu$g/mL of Eugenia caryophyllus and 3,270 $\mu$g/mL of Panax ginseng C. A. Meyer, respectively. Antioxidant activity of Eugenia caryophyllus was equal to 38.0$\pm$1.2 mg VCEAC(vitamin C equivalent antioxidant capacity)/ g herb. The highest and lowest NDA values were 1.81 of Astrgalus membranaceus Bunge and 1.01 of Raphani seed and Lespedeza tomentosa Sieb, respectively. Eleven medicinal herbs with high antioxidant activity and/or NDA were selected to make an herbal tea. The herbal tea had high antioxidant activity (50 $\mu$g/mL $IC_{50}$/ and 22.4$\pm$1.4 mgVCEAC/g) and NDA (1.243). The medicinal herb tea could help smokers quitting smoking by degrading and exhausting nicotine accumulated in body and removing reactive oxygen species.

• Journal of Environmental Health Sciences
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• v.39 no.6
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• pp.483-491
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• 2013

Objectives: Electronic cigarettes are battery powered devices that convert a nicotine-containing liquid into an inhalable vapor. The device aerosolizes nicotine so that it is readily entrained into the respiratory tract, from where it enters the bloodstream. Information on the safety of E-cigarettes is required. Methods: Seventeen articles on studies analyzing toxic substances in the liquid and gas phases of electronic cigarettes were reviewed. Results: Tobacco-specific nitrosamines, bis(2-ethylhexyl) phthalate, formaldehyde and acetaldehyde, known to be carcinogenic agents in humans or animals, were detected in the liquid and gas phases. In addition, diethyl phthalate, acetone, ethanol, cresol, xylene, propylene, styrene, triethylene glycol, tetraethylene glycol, pentaethylene glycol cis-3-hexen-1-ol, methyl cinnamate and undecane were identified in the liquid and gas phases of E-cigarettes. Propylene glycol, glycerin, 1-methoxy-2-propanol, 1-hydroxy-2- propanone, acetic acid, 1-menthone, 2,3-butanediol, menthol, carvone, maple lactone, benzyl alcohol, 2-methyl-2-pentanoic acid, ethyl mantel, ethyl cinnamate, myosamine, benzoic acid, 2,3-bipyridine, cotinine, hexadecanoic acid, and 1'1-oxybis-2-propanol were detected in the vapors of E-cigarettes. Conclusion: The hazardous compounds identified in the liquid and gas phases of E-cigarettes should be controlled for the lowest concentrations in the raw materials and production procedures.

• Korean Journal of Health Education and Promotion
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• v.29 no.3
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• pp.1-14
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• 2012

Objectives: The purpose of this study was to determine if smoking cessation programs (SCPs) are effective for adults through a systematic review of the results of such programs in large randomized controlled trials (RCTs). Methods: The PICO (Patient, Intervention, Comparator, Outcome) strategy was established, 1,160 literature from domestic and foreign electronic databases was reviewed, and 22 references were selected based on the inclusion and exclusion criteria. The quality of each reference was evaluated using the Scottish Intercollegiate Guidelines Network tool, and meta-analysis was carried out. Results: The SCPs were significantly effective for adult smokers. Smoking cessation counseling, education, and smoking cessation medications such as nicotine patch were more effective than the other interventions. However, the results showed short-term effects (within six months), and differences were observed among the SCPs. For the outcome measures for SCPs, the abstinence rate of seven days was mainly used, but differences were identified between the CO level and the cotinine-verified abstinence rate of smoking cessation. Conclusions: For a smoking cessation program for adult smokers, the strength of the evidence of the program's effectiveness in RCTs that provide the identified intervention strategies should be considered.

• Research in Community and Public Health Nursing
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• v.16 no.4
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• pp.478-487
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• 2005

Purpose: This study was to examine the achievement rate of smoking cessation, to identify obstacles to smoking cessation, and to find means to achieve the goal of smoking cessation in college smokers. Method: This study was conducted from April 26th to September 13th 2004 and used a one-shot design. The subjects selected by convenient sampling were 29 college smokers who smoked over one cigarette a day, had a positive level of urine cotinine, participated in smoking cessation education 3 times. Thereafter, individual interaction was processed between the researcher and the subject using an interaction instrument. Data were analyzed based on frequencies.,percentages and means using SPSS/Win 10.0. Results: The achievement rate of smoking cessation was 20.7% (6 students). The biggest obstacles smoking cessation were smoking stimuli (29 students) and lack of control (25 students). Among detailed obstacles, the biggest one was smoking at regular times, which was followed by withdrawal symptoms, smoking on drinking, and company with other smokers. The most effective means of smoking cessation mentioned by the subjects were in order of avoiding drinking situations, taking deep breaths, and exercising. Conclusion: The results of this study, using King's theory, showed that individual interaction is effective in achieving smoking cessation. Therefore, it is suggested to make further study and broaden smoking cessation education for college smokers.

• Archives of Pharmacal Research
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• v.16 no.2
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• pp.89-93
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• 1993

Incubation of $S(-)-^3H$-nicotine with rabbit lung microsomes in the presence of dioxygen and NADPH results in the formation of metabolities that bind covalently to microsomal macro-molecules. The addition of cytochrome P-450 monooxygenase inhibitors, $\alpha$-methylbenzyl ami-nobenzotriazole and aroclor 1260, inhibited both (S)-nicotine metabolism and covalent binding. The relative rates of oxidation of nicotine $\Delta^{1',5'}$ iminium ion to continine indicates that lung $100,000\times{g}$ supematant catalyzed this oxidation approximately 18 times slower than that of liver system based on mg of protein, and increased covalent interactions. Since than that of liver system based on mg of protein, nd increased covalent interactions. Since the activity of lung iminium oxidase appears much lowr than the liver, it is tempting to speculate that localized concentrations of nicotine $\Delta^{1',5'}$ iminium ion in the lung will survive for a longer period of time. These results support that cytochrome P-450 catalyzed oxidation of nicotine leads to the formation of reactive nad electrophilic intemediates capable of chemical interactions with biomacromolecules.