• 한국자기공명학회논문지
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• 제15권2호
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• pp.115-127
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• 2011

A newly developed cost-effective approach to prepare $^{15}N/^{13}C$-labeled protein for NMR studies is presented. This method has been successfully applied to isotopically labeling of PTK6 SH2 domain and MTH 1880 protein. The production method generates cell density using a growing media containing $^{15}NH_4Cl$, $^{12}C_6$-D-glucose. Following a doubling time period for unlabeled metabolite exhaustion and then addition $^{13}C_6$-D-glucose into a M9 growing media, the cells are induced. Our results demonstrate that in order to get full incorporation of $^{13}C$, the isotopes are not totally required during the initial growth phase before induction. The addition of small amounts of $^{13}C_6$-D-glucose to the induction phase is sufficient to obtain more than 95% incorporation of isotopes into the protein. Our optimized protocol is two-thirds less costly than the classical method using $^{13}C$ isotope during the entire growth phase.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 제37회 하계학술대회 논문집 A
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• pp.420-421
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• 2006

The cost-effective reduction of greenhouse gas(GHG) emission to avert the most severe impacts of climate change remains one of the widely accepted priorities for global action. In order to facilitate cost-effective abatement strategies, the Kyoto Protocol introduced three mechanisms, or flexible instruments, the Emissions Trading(ET), the Joint Implementation(JI) and the Clean Development Mechanism(CDM). The CDM enables Annex I countries to the Kyoto Protocol to partially meet cost-effectively their emission reduction commitments by undertaking GHG mitigation Projects in developing countries, which do not have any GHG abatement obligations and where the emission reductions are cheaper. One of the major barriers hampering the wide spread implementation of CDM is the high transaction costs associated with the initial identification of promising CDM projects. This paper presents development of a pre-validation program of CDM. The developed program may provide a useful aid to potential investors and project developers as a supportive pre-evaluation tool, and may become an effective tool for the promotion of renewable energy and fuel switching projects.

• Asian Pacific Journal of Cancer Prevention
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• 제14권2호
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• pp.853-857
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• 2013

Objectives: Breast cancer is a leading cause of morbidity and mortality in women worldwide. Breast screening in normal and/or asymptomatic women is essential to reduce the burden of breast malignancies. Our study aimed to identify possible risk- and/or co-factors associated with breast screening in North Indian women. Methods: A public health research survey was conducted among 100 women of North Indian ethnicity during clinic visits in a 6-month timeline (April-October 2012). Demographic and clinical data, including mammography screening, were recorded in the questionnaire-based proforma after conducting a 10 minute interview. Written informed consent was taken from all the participants. Results: The mean age of the participants was $32.2{\pm}9.9$ years. Out of 100 women, 6% had family history of breast disease. Breast-related complaints/malignancy, including galactorrhoea, mastitis, axillary lump, fibrocystic disease, fibroadenosis and adenocarcinoma were observed in 41% participants; age stratification revealed that 82.9% of this group (n=41) were <30 years, while 9.7% and 7.3% were >30 years and 30 years of age, respectively. 32% participants underwent mammography screening and 8% had breast ultrasound imaging. Age stratification in the mammography screening group demonstrated that 24 women were <40 years, while 7 women were >40 years. Conclusions: Our pilot study identified possible co-factors affecting breast screening in North Indian women. These findings may be beneficial in early detection of breast abnormalities, including malignancies in women susceptible to breast cancer, and thus aid in future design of cost-effective screening strategies to reduce the increasing burden of breast carcinoma in women worldwide.

• 센서학회지
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• 제23권2호
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• pp.82-86
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• 2014

This paper reports the development of a platform for tracking and analysis of animal locomotion. The platform is composed of a commercial webcam, a metal stand for the webcam, and a plastic bathtub as a cage. Using it, researchers can track and analyze an animal's movement within the plastic bathtub's dimensions of $100cm{\times}100cm{\times}55cm$ in a cost-effective manner. After recording the locomotion of an animal with $1920{\times}1080$ resolution at a rate of 30 frames per second, finding the position of the animal in each frame and analyzing the ambulation pattern were executed with custom software. To evaluate the performance of the platform, movements of imprinting control region mice and transgenic mice were recorded and analyzed. The analysis successfully compared velocity, moving pattern, and total moving distance for the two mouse groups. In addition, the developed platform can be used not only in simple motion analysis but also in various experimental conditions, such as a water maze, by easy customization of the platform. Such a simple and cost-effective platform yields a powerful tool for animal ambulatory analysis.

• International Journal of Air-Conditioning and Refrigeration
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• 제17권1호
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• pp.15-24
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• 2009

The energy usage and the economical feasibility of the typical two story office building in the three urban locations of South Korea are evaluated as the eight orientations. The smallest energy consume is shown at the true south. The ranges of the low energy consume are $-3l5^{\circ}{\sim}0^{\circ}\;and\;-135^{\circ}{\sim}-180^{\circ}$. There are obvious advantages of passive solar designs such as using a fully glazed facade at the true south in the building. The General Low voltage plan is the effective way for the office building when does not required the high voltage electricity. The energy cost of KEPCO is compared to that of XCEL ENERGY. The portion of the customer charge of XCEL ENERGY is about 10% but it is about 50% of the total tariff of KEPCO. The effective way to save the energy cost is by reducing the operating energy of XCEL ENERGY plane but the most effective way is reduce the contracting energy of KEPCO plane.

• 한국정보통신학회논문지
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• 제16권5호
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• pp.1029-1034
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• 2012

본 논문에서는 US-PCS(US-personal communications services)를 위해 사용이 가능한 저가격 고성능 FBAR (film bulk acoustic resonator) 듀플렉서(duplexer) 모듈(module)을 제시하였다. FBAR 소자는 일반적인 실리콘(Si) 기반의 공정보다 가격경쟁력이 우수한 유리(glass) 웨이퍼 기반의 패키지를 개발하여 적용하였다. FBAR 듀플렉서 모듈의 전송단(Tx)과 수신단(Rx)에서 얻어진 최대 삽입손실 특성은 각각 1.9 dB와 2.4 dB이다. 전송단 및 수신단 FBAR 소자와 본딩(bonding)된 유리 기반의 웨이퍼 및 PCB 기판과 몰딩(molding) 물질을 모두 포함하는 FBAR 듀플렉서 모듈의 전체 두께는 1.2 mm이다.

• Membrane and Water Treatment
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• 제10권4호
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• pp.259-264
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• 2019

Cost effective clay adsorptive microfiltration membranes were synthesized to remove Cr (III) from high polluted water. Raw and calcined bentonite were mixed in order to decrease the shrinkage and also increase the porosity; then, 20 wt% of carbonate was added and the samples, named B (without carbonate) and B-Ca20 (with 20 wt% calcium carbonate) were uniaxially pressed and after sufficient drying, fired at $1100^{\circ}C$ for 3 hours. Then, physical and mechanical properties of the samples, their phase analyses and microstructure and also their ability for Cr(III) removal from high polluted water (including 1000 ppm Cr (III) ions) were studied. Results showed that the addition of calcium carbonate lead the porosity to increase to 33.5% while contrary to organic pore formers like starch, due to the formation of wollastonite, the mechanical strength not only didn't collapse but also improved to 36.77 MPa. Besides, sample B-Ca20, due to the presence of wollastonite and anorthite, could remove 99.97% of Cr (III) ions. Hence, a very economic and cost effective combination of membrane filtration and adsorption technology was achieved for water treatment which made microfiltration membranes act even better than nanofiltration ones without using any adsorptive nano particles.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2010년도 춘계학술대회 논문집
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• pp.2303-2308
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• 2010

We studied the cost-volume supply characteristic of public transportation systems focused on Bi-modal Tram in the main cities to analyze the applicability and status for the new transit system Bi-modal Tram as public transportation system. The operation cost considering the characteristic of vehicle, facilities, operation and average cost for respective public transportation system and the time cost considering the travel and transfer time are defined to the social cost, and the cost-volume supply curve is based on this social cost. The cost-volume supply characteristic between public transportation modes in the city is determined on the basis of cost-volume supply curve. Through the comparison between cost-volume supply characteristic of main transportation systems, it is analyzed about the relation between public transportation systems in the city and the characteristic for proper service provision. The application of Bi-modal Tram in the city is concluded that it is effective to reduce the social cost on the existing public transportation system.

• 전력전자학회:학술대회논문집
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• 전력전자학회 2000년도 전력전자학술대회 논문집
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• pp.456-459
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• 2000

Due to cost-effective and compact system design IPM-based inverters are now being seen as an attractive alternative to conventional discrete-based inverters technique for low power ac drives in particular such as washing machines refrigerators and air-conditioners. Fairchild-IPM newly developed in order to provide the advantages of the lowest cost and better performance is discussed and its specification is given.

• 한국건축시공학회지
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• 제12권6호
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• pp.624-635
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• 2012

Construction projects, including housing, are carried out over long periods of time. According to changes to the construction period, the cost of input materials and wages also changes. Therefore appropriate management is important in order to minimize cost risks caused by fluctuations in prices. In Korea, housing units are usually sold in lots prior to construction completion. Therefore, careful management of input elements such as materials and equipment that are sensitive to price fluctuations is very important. This study deals with how the price fluctuation of materials, labor, and equipment influences the change of housing cost and seeks a way for cost management through identifying key resources sensitive to price fluctuation. As a result, a change to the housing cost index multiplies depending on cost changes of materials and labor together. Labor costs are a major factor on the housing cost index. In addition, certain types of materials and labor input to housing construction greatly influence price fluctuations. Thus, it is found that managing those main cost factors is the key for effective cost management.