• Title/Summary/Keyword: correlated parameters

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Statistical Modeling of Joint Distribution Functions for Reliability Analysis (신뢰성 해석을 위한 결합분포함수의 통계모델링)

  • Noh, Yoojeong;Lee, Sangjin
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.5
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    • pp.2603-2609
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    • 2014
  • Reliability analysis of mechanical systems requires statistical modeling of input random variables such as distribution function types and statistical parameters that affect the performance of the mechanical systems. Some random variables are correlated, but considered as independent variables or wrong assumptions on input random variables have been used. In this paper, joint distributions were modeled using copulas and Bayesian method from limited number of data. To verify the proposed method, statistical simulation tests were carried out for various number of samples and correlation coefficients. As a result, the Bayesian method selected the most probable copula types among candidate copulas even though the candidate copula shapes are similar for low correlations or the number of data is limited. The most probable copulas also yielded similar reliabilities with the true reliability obtained from a true copula, so that it can be concluded that the Bayesian method provides accurate statistical modeling for the reliability analysis.

Effects of Rice Bran and Wheat Bran on Intestinal Physiology and Small-bowel Morphology in Rats

  • Park, Young-Sun;Jang, Jae-Hee;Bae, Bok-Sun;Seo, Jung-Sook
    • Nutritional Sciences
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    • v.3 no.1
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    • pp.3-10
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    • 2000
  • The present study was aimed at investigating the nutritional and physiological significance of rice bran as a source of dietary fiber as compared to pectin and wheat bran. The parameters for comparison included hypertrophy and morphology of intestines, stool weights and villus marker enzyme activity. For 6 weeks, 10 Sprague Dawley male rats were given one of six experimental diets: 1% cellulose control (CC), 5% pectin (P5), 5% rice bran(RB5), 10% rice bran(RB10), 5% wheat bran (WB5) or 10% wheat bran (WB10) based on the level of dietary fiber. Among experimental groups, food efficiency ratio and body weight gain was comparable. RB10 increased cecal and colonic tissue weights and content weights of cecum and colon as much as P5 did. Stool weight was positiviely correlated with colonic tissue weight (r=0.727, P<0.001), with colonic content weight(r=0.647, P<0.001). Small intestine length increased most in the P5 group, followed by the RB10 group. The scanning electron micrograph of jejunal villi from rice bran groups showed a leaf-shaped, smooth and regular pattern, whereas that of CC group produced a rather long shape. The wheat bran groups showed an irregular leafshaped pattern, and the pectin group typically produced leaf-shaped villi with surface damage. The activities of villus marker enzymes (maltase and sucrase) were higher in the bran-fed rats than in the control or pectin-fed rats. The results indicate than not only dietary fiber amounts but also fiber sources are closely related to the physiology and morphology of the large and small intestines in rats. Rice bran exerted effects on fecal output and trophic effects on the intestines similar to those of pectin.

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Incidence of Chronic Shunt-dependent Hydrocephalus after Surgical or Endovascular Treatment of Ruptured Intracranial Aneurysm (동맥류 결찰술 시행군과 GDC색전술 시행군에서 지주막하 출혈 후 만성 션트-의존성 수두증의 발생빈도)

  • Kwon, Young-Yi;Cho, Maeng Ki;Park, Bong-Jin;Sung, Jung-Nam;Kim, Young-Joon
    • Journal of Korean Neurosurgical Society
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    • v.30 no.sup1
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    • pp.68-72
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    • 2001
  • Objective : The goal of this study was to document the influence of the treatment modality(surgery versus endovascular treatment) on the development of chronic shunt-dependent hydrocephalus in a series of 296 patients treated after aneurysmal subarachnoid hemorrhage(SAH). Methods : The following parameters were retrospectively analyzed for association with chronic shunt-dependent hydrocephalus : 1) Age and Sex, 2) Hunt and Hess grade, 3) Fisher computed tomographic grade, 4) aneurysm location, and 5) treatment modality(surgery versus endovascular treatment). Results : Thirty-six of 251 patients(14.3%) who survived the SAH and its neurological and/or medical sequelae underwent definitive shunting for treatment of chronic hydrocephalus. The rate of shunt dependency was positively correlated with a higher age, a higher Hunt and Hess grade, a higher Fisher computed tomographic grade, and aneurysms arising at the anterior communicating artery(p<0.05). Conclusion : The results of the present study indicate that the treatment modality used does not affect the risk of the later development of chronic shunt-dependent hydrocephalus(surgery, 16.2% [25 of 154] ; endovascular treatment, 11.3% [11 of 97] ; p=0.45).

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Comparison of Root Images between Post-Myelographic Computed Tomography and Magnetic Resonance Imaging in Patients with Lumbar Radiculopathy

  • Park, Chun-Kun;Lee, Hong-Jae;Ryu, Kyeong-Sik
    • Journal of Korean Neurosurgical Society
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    • v.60 no.5
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    • pp.540-549
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    • 2017
  • Objective : To evaluate the diagnostic value of computed tomography-myelography (CTM) compared to that of magnetic resonance imaging (MRI) in patients with lumbar radiculopathy. Methods : The study included 91 patients presenting with radicular leg pain caused by herniated nucleus pulposus or lateral recess stenosis in the lumbar spine. The degree of nerve root compression on MRI and CTM was classified into four grades. The results of each imaging modality as assessed by two different observers were compared. Visual analog scale score for pain and electromyography result were the clinical parameters used to evaluate the relationships between clinical features and nerve root compression grades on both MRI and CTM. These relationships were quantified by calculating the receiver-operating characteristic curves, and the degree of relationship was compared between MRI and CTM. Results : McNemar's test revealed that the two diagnostic modalities did not show diagnostic concurrence (p<0.0001). Electromyography results did not correlate with grades on either MRI or CTM. The visual analog pain scale score results were correlated better with changes of the grades on CTM than those on MRI (p=0.0007). Conclusion : The present study demonstrates that CTM could better define the pathology of degenerative lumbar spine diseases with radiculopathy than MRI. CTM can be considered as a useful confirmative diagnostic tool when the exact cause of radicular pain in a patient with lumbar radiculopathy cannot be identified by using MRI. However, the invasiveness and potential complications of CTM are still considered to be pending questions to settle.

The Study of the Subjective Symptoms according to Frontal Lobe Damage and Change in Neurocognitive Function in Traumatic Head Injury Patients (두부외상 환자에서 전두엽 손상과 신경인지기능 변화에 따른 주관적인 증상 연구)

  • Kim, Jun-Won;Han, Doug-Hyun;Kee, Baik-Seok;Park, Doo-Byung
    • Anxiety and mood
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    • v.8 no.1
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    • pp.31-40
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    • 2012
  • Objective : The purpose of this study was to analyze the correlation between symptom severity and neurocognitive factors in traumatic head injury patients. In addition, the effect of frontal lobe damage on these parameters was examined. Methods : We selected 18 patients who had brain damage for the moderate to severe traumatic brain injury (MSTBI) group, and 17 patients who met the diagnostic criteria for post-traumatic stress disorder (PTSD) without the finding of brain damage for the comparison group. For the evaluation of neurocognitive function, K-WAIS, Rey-Kim Memory Test, K-FENT, WCST, and MMPI-2 were used. Results : The results of the comparison (using the malingering scale) revealed that the values of PDS and PK, which express the severity of symptoms, and the values of the validity scale F, F (B), and F (P) were significantly higher in the overly-expressed group. F (B) in overly-expressed group and PK, Pt, and Sc in the properly-expressed group had significant correlation with the severity of symptoms. F (B), S, and Stroop error inhibition in PTSD, and PK, Pt, Sc, and MQ in MSTBI had significant correlation with the severity of symptoms. The results of the comparison based on the finding of frontal lobe damage revealed that PDS, EIQ, and MQ ware significantly higher in the group without brain damage. Conclusions : It was revealed that each neurocognitive factor was correlated with the severity of symptoms. There was a decrease in complaints or symptoms reported by the frontal lobe injury group, and this is believed to be due to degenerative change in the personality and emotional functioning of these patients following frontal lobe damage.

Dynamics and Instability of a Polymeric Paint in Roll Coating Process for Automotive Pre-coating Application (자동차 선도장을 위한 롤코팅 공정에서 고분자 도료의 동적 거동 및 불안정성)

  • Kim, Jin-Ho;Lee, In-Jun;Noh, Seung-Man;Kang, Choong-Yeol;Nam, Joon-Hyun;Jung, Hyun-Wook;Park, Jong-Myung
    • Polymer(Korea)
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    • v.35 no.6
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    • pp.574-579
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    • 2011
  • 3-Roll coating process as a key application technology for manufacturing automotive pre-painted metal-sheets has been studied. The 3-Roll coating system for this study consists of pick-up roll for picking up and distributing coating liquid from the reservoir, metering roll to properly meter coating liquid in metering gap regime, and applicator roll for directly transferring liquid into metal-sheet surface. Flow dynamics and operable coating windows of a polymeric paint (primer) with shear-thinning rheological property have been correlated with processing parameters such as speed ratio and metering gap between pick-up and metering rolls. In the uniform coating regime, dry coating thickness increased with increasing metering gap or decreasing speed ratio. Ribbing and cascade instabilities were observed in low speed and high speed ratio conditions, respectively. It is revealed that lower speed ratio makes severity and wavelength of the ribbing increase, aggravating flow instability in coating systems.

Bone Mineral Density and Osteoporotic Vertebral Fractures in Traditional, Unassisted, Free-Diving Women (Haenyeos)

  • Seo, Jun-Yeong;Ha, Kee-Yong;Kim, Young-Hoon;Kim, Seong-Chan;Yoon, Eun-Ji;Park, Hyung-Youl
    • Journal of Korean Medical Science
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    • v.33 no.48
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    • pp.316.1-316.10
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    • 2018
  • Background: Water pressure and muscle contraction may influence bone mineral density (BMD) in a positive way. However, divers experience weightlessness, which has a negative effect on BMD. The present study investigated BMD difference in normal controls and woman free-divers with vertebral fracture and with no fracture. Methods: Between January 2010 and December 2014, traditional woman divers (known as Haenyeo in Korean), and non-diving women were investigated. The study population was divided into osteoporotic vertebral fracture and non-fracture groups. The BMD of the lumbar spine and femoral neck was measured. The radiological parameters for global spinal sagittal balance were measured. Results: Thirty free-diving women and thirty-three non-diving women were enrolled in this study. The mean age of the divers was $72.1{\pm}4.7$ years and that of the controls was $72.7{\pm}4.0$ years (P = 0.61). There was no statistical difference in BMD between the divers and controls. In divers, cervical lordosis and pelvic tilt were significantly increased in the fracture subgroup compared to the non-fracture subgroup (P = 0.028 and P = 0.008, respectively). Sagittal vertical axis was statistically significantly correlated with cervical lordosis (Spearman's rho R = 0.41, P = 0.03), and pelvic tilt (Spearman's rho R = 0.46, P = 0.01) in divers. Conclusion: BMD did not differ significantly between divers and controls during their postmenopausal period. When osteoporotic spinal fractures develop, compensation mechanisms, such as increased cervical lordosis and pelvic tilt, was more evident in traditional woman divers. This may be due to the superior back muscle strength and spinal mobility of this group of women.

Cutaneous Patches to Monitor Myoelectric Activity of the Gastrointestinal Tract in Postoperative Pediatric Patients

  • Taylor, Jordan S.;Ruijter, Vivian de;Brewster, Ryan;Navalgund, Anand;Axelrod, Lindsay;Axelrod, Steve;Dunn, James C.Y.;Wall, James K.
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.22 no.6
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    • pp.518-526
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    • 2019
  • Purpose: Limited means exist to assess gastrointestinal activity in pediatric patients postoperatively. Recently, myoelectric gastrointestinal activity recorded by cutaneous patches has been shown in adult patients to be predictive of clinical return of gastrointestinal function postoperatively. The aim of this case series is to demonstrate the feasibility of this system in pediatric patients and to correlate myoelectric signals with return of bowel function clinically. Methods: Pediatric patients undergoing abdominal surgery were recruited to have wireless patches placed on the abdomen within two hours postoperatively. Myoelectric data were transmitted wirelessly to a mobile device with a user-interface and forwarded to a cloud server where processing algorithms identified episodes of motor activity, quantified their parameters and nominally assigned them to specific gastrointestinal organs based on their frequencies. Results: Three patients (ages 5 months, 4 year, 16 year) were recruited for this study. Multiple patches were placed on the older subjects, while the youngest had a single patch due to space limitations. Rhythmic signals of the stomach, small intestine, and colon could be identified in all three subjects. Patients showed gradual increase in myoelectric intestinal and colonic activity leading up to the first recorded bowel movement. Conclusion: Measuring myoelectric intestinal activity continuously using a wireless patch system is feasible in a wide age range of pediatric patients. The increase in activity over time correlated well with the patients' return of bowel function. More studies are planned to determine if this technology can predict return of bowel function or differentiate between physiologic ileus and pathologic conditions.

A Comparison of Mental Health of School Age Children between Urban and Rural Area and a Correlation Analysis of Subjective Mental Health Indicators and Heart Rate Variability (도시와 산촌 학령기아동의 정신건강 비교 및 주관적 정신건강 지표와 심박변이도(HRV)의 상관관계 분석)

  • Bang, Kyung Sook;Lee, In Sook;Kim, Sung Jae;Yoon, Jae Hee;Lee, Juna
    • Journal of the Korean Society of School Health
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    • v.30 no.3
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    • pp.266-273
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    • 2017
  • Purpose: This study was performed to compare the mental health of school age children residing in urban and rural areas and to analyze the correlations between the subjective mental health indicators such as depression and attention deficit-hyperactivity behavior and heart rate variability (HRV) indicators. Methods: For this study, a convenience sample of one hundred and three children was recruited. Depression and attention deficit-hyperactivity behavior were measured using self-reported questionnaires and HRV indicators were measured using an electronic instrument. Results: Among the HRV parameters of the rural children, their normalized LF and the LF / HF were significantly lower than those of the urban children. The RMSSD and the normalized HF were statistically significantly higher. The level of depression showed a significant positive correlation with the normalized LF and LF/HF, but showed a negative correlation with the normalized HF. Also, the level of attention deficit-hyperactivity behavior was significantly correlated with the normalized LF, LF/HF, and the normalized HF. Conclusion: Based on the findings, we expect that HRV indicators can be applied to predict the level of depression and attention deficit-hyperactivity behavior in elementary school children.

Behavioral and cardiac responses in mature horses exposed to a novel object

  • Lee, Kyung Eun;Kim, Joon Gyu;Lee, Hang;Kim, Byung Sun
    • Journal of Animal Science and Technology
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    • v.63 no.3
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    • pp.651-661
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    • 2021
  • This study aimed to investigate whether breed, sex, and age affected temperament differently (more or less neophobic) in mature horses during a novel object test. The study included Jeju crossbred (n = 12, age = 9.42 ± 4.57 y), Thoroughbred (n = 15, age = 10.73 ± 3.09 y), and Warmblood horses (n = 12, age = 13.08 ± 3.55 y) with the females (n = 22, age = 11.36 ± 4.24 y) and geldings (n = 17, age = 10.65 ± 3.66 y). Jeju crossbreds (Jeju horse × Thoroughbred) are valuable considering their popular usage in Korea, but limited studies have explored temperament of Jeju crossbred horses. A trained experimenter touched the left side of the neck with a white plastic bag (novel object). The test ended when the horse stopped escape response and heart rate (HR) dropped to baseline. Behavioral score and escape duration were measured as behavioral variables. Multiple variables related to HR and heart rate variability (HRV) were measured to reflect emotional state. These included basal HR (BHR), maximum HR (MHR), delay to reach maximum heart rate (Time to MHR), standard deviation of beat-to-beat intervals (SDNN), root mean square of successive differences (RMSSD), and ratio of low to high frequency components of a continuous series of heartbeats (LF/HF). Statistics revealed that Thoroughbreds had significantly higher behavioral scores, and lower RMSSD than Jeju crossbreds (p < 0.05), suggesting greater excitement and fear to the novel object in Thoroughbreds. None of the behavioral or cardiac parameters exhibited sex differences (p < 0.05). Age was negatively correlated with SDNN and RMSSD (p < 0.05), indicating that older horses felt more anxiety to the novelty than younger horses. Thoroughbreds and females had distinct correlations between behavioral and HRV variables in comparison with other groups (p < 0.05), implying that escape duration might be a good indicator of stress, especially in these two groups. These results are expected to improve equine welfare, safety and utility, by providing insights into the temperament of particular horse groups, to better match reactivity levels with specific functions.