• Journal of IKEEE
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• v.11 no.3
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• pp.108-116
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• 2007

This paper proposed an analyzable parameter and its analytic method to provide more accurate information than currently employed 4 channels system which uses pulse wave velocity (PWV) information of the volume pulse wave measured from 4 arterial channels for the characterization of arterial vessel. In order to verify the volume pulse waves on 4 sites were simultaneously acquired subjects aged from 12 to 81 years old. and the proposed parameters were extracted from time (UT) was then compared with blood pressure. Then, the regression analyses were done relationships among the proposed parameter and others, such as aging, pulse transit time pressure (BP). The followings are the results of linear regression analysis of the proposed parameter for total 50 normal subjects. We selected any two subjects (58 years and 27 years) and measured PPG (photoplethysmogram) and BP of before and after exercise. The coefficient of correlations between BP and UT observed was -0.928 for 50 years subject, and -0.922 for 20 years subject. For total 50 normal subjects, in case of correlation between the pulse transit time and BP, the result showed -0.170 on left side and -0.233 on right side, and the coefficient value of correlation between the pulse transit time and UT was -0.607 on left side and -0.510 on right side. UI is strongly correlated with the pulse transit time than BP. Hence, we believe that the proposed parameter is related with the index of arterial stiffness.

• Journal of Magnetics
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• v.9 no.2
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• pp.52-59
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• 2004

As deposited and annealed MTJs with the structure of $Ta(5 nm)/Cu(10 nm)/Ta(5 nm)/Ni_{80}Fe_{20}(2 nm)/Cu(5 nm)/ Ir_{25}Mn_{75}(10 nm)/Co_{70}Fe_{30}(2.5 nm)/Al-O/Co_{70}Fe_{30}(2.5nm)/Ni_{80}Fe_{20}(t)/Ta(5nm)/Ni_{80}Fe_{20}(t)/Ta(5 nm)$, where t=10, 30, 60 and 100 nm were characterized by XRD and magnetic hysteresis loops measurements. The XRD measurements were done in grazing incidence $(GID scan-2{\theta})$ and ${\theta}-2{\theta}$ geometry, by rocking curve $(scan-{\omega})$ and pole figures in order to establish correlation between texture and crystallites size and magnetic parameters of exchange biased and interlayer coupling. The variations of shifting and coercivity field of free and pinned layers after annealing in $300^{\circ}C$ correlate with the improvement of ［111］ texture and grains size of $Ni_{80}Fe_{20}$ and $Ir_{25}Mn_{75}$ respectively. The exchange biased and the coercivity fields of the pinned layer linearly increased with increasing grain size of $Ir_{25}Mn_{75}$, The reciprocal proportionality between interlayer coupling and coercivity fields of the free layer and grain size of $Ni_{80}Fe_{20}$ was found. The enhancement of interlayer coupling between pinned and free layers, after annealing treatment, indicates on the correlated in-phase roughness of dipolar interacting interfaces due to increase of crystallites size of $Ni_{80}Fe_{20}$.

• Journal of the Korean Society of Clothing and Textiles
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• v.36 no.9
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• pp.928-939
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• 2012

This study evaluates wear comforts of water-vapor-permeable (WVP) garments through a measurement of various parameters such as skin and rectal temperatures, microclimate between skin and clothing, sweat rate, and subjective sensations (thermal, wet and comfort sensations) to correlate the physiological responses of the human body with its comfort feeling. Wear comfort during a specific exercise on a treadmill in a climatic chamber (temperature T = $20{\pm}0.5^{\circ}C$ and relative humidity H = $50{\pm}10%$) were studied using eight men wearing seven sportswear outfits (a long sleeve shirts and a long pants) made with seven different WVP fabrics. A comfort sensation was found to be highly correlated with skin T (p<.001), microclimate (T and H) between skin and clothing (p<.001) and sweat rate (p<.05). A regression model correlating comfort sensations and physiological responses obtained from wearer trials could be established: Y = 14.167 - 0.362 ${\times}$ X1 + 0.424 ${\times}$ X2 - 0.238 ${\times}$ X3 - 0.561 ${\times}$ X4 + 0.253 ${\times}$ X5 + 0.214 ${\times}$ X6 - 0.393 ${\times}$ X7 + 0.023 ${\times}$ X8 - 0.043 ${\times}$ X9. (Y = comfort sensation, X1 = forehead skin T, X2 = forearm skin T, X3 = hand skin T, X4 = thigh skin T, X5 = T of chest microclimate, X6 = T of thigh microclimate, X7 = chest sweat rate, X8 = H of back microclimate, X9 = H of thigh microclimate. The regression model obtained in this work can be used by manufacturers to objectively estimate the comfort sensation of sportswear before it is introduced to the consumer market. This study provides salient information to sportswear manufacturers and sportswear consumers.

• Korean Journal of Veterinary Research
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• v.55 no.4
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• pp.247-252
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• 2015

Exercise is one of the most common stressors in horses. Although various physiological parameters such as cortisol respond to exercise, there is no reliable parameter for the measurement of exercise-induced stress in sport horses. This study was performed to discover a new biomarker with high sensitivity for exercise-induced stress. The expression of fos mRNA was increased more than 10-fold in horse blood samples collected after an hour of exercise, as compared with before the exercise. The plasma cortisol levels were also increased after the exercise, but only by about two-fold. The fos mRNA levels were well-correlated with plasma cortisol concentrations. These findings suggest that fos mRNA expression in blood may be useful for the measurement of exercise-induced stress in horses.

• Journal of the Korean earth science society
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• v.22 no.1
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• pp.20-29
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• 2001

P wave traveltime delays has been measured and a preliminary tomouaphic inversion has been performed using the data collected from the network deployed by Korea National University of Education in the southcentral part Korea. The maximum variation in relative traveltime residuals is almost 0.7 seconds. A large azimuthal variation in traveltime residuals is observed at the stations in the northwestern part of the study area. This might indicate the existence of lateral velocity heterogeneity beneath the study area. Although, the inverted tomographic image seems to be correlated with the tectonic boundary between Kyunggi Massif and Okcheon Belt, the confidence level is presently low. We should place on the importance of this study for finding preferable inversion parameters and predicting probable result. Better tomographic image of the study area can be obtained in the near future when the data are accumulated.

• Proceedings of the KIEE Conference
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• 2008.07a
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• pp.1230-1231
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• 2008

The effect of content of $Al_2O_3+Y_2O_3$ sintering additives on the densification behavior, mechanical and electrical properties of the pressureless-sintered $SiC-ZrB_2$ electroconductive ceramic composites was investigated. The $SiC-ZrB_2$ electroconductive ceramic composites were pressureless-sintered for 2 hours at 1,700[$^{\circ}C$] temperatures with an addition of $Al_2O_3+Y_2O_3$(6:4 mixture of $Al_2O_3$ and $Y_2O_3$) as a sintering aid in the range of 8${\sim}$20[wt%]. Phase analysis of $SiC-ZrB_2$ composites by XRD revealed mostly of ${\alpha}$-SiC(6H), $ZrB_2$ and In Situ YAG($Al_5Y_3O_{12}$). The relative density, flexural strength, Young's modulus and vicker's hardness showed the highest value of 89.01[%], 81.58[Mpa], 31.437[GPa] and 1.34[GPa] for $SiC-ZrB_2$ composites added with 16[wt%] $Al_2O_3+Y_2O_3$ additives at room temperature respectively. Abnormal grain growth takes place during phase transformation from ${\beta}$-SiC into ${\alpha}$-SiC was correlated with In Situ YAG phase by reaction between $Al_2O_3$ and $Y_2O_3$ additive during sintering. Compositional design and optimization of processing parameters are key factors for controlling and improving the properties of SiC-based electroconductive ceramic composites. In this paper, it is convinced that ${\beta}$-SiC based electroconductive ceramic composites for heaters or ignitors can be manufactured by pressureless sintering.

• Geomechanics and Engineering
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• v.12 no.3
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• pp.441-464
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• 2017

The determination of the mixture parameters of stabilization has become a great concern in geotechnical applications. This paper presents an effort about the application of artificial intelligence (AI) techniques including radial basis neural network (RBNN), multi-layer perceptrons (MLP), generalized regression neural network (GRNN) and adaptive neuro-fuzzy inference system (ANFIS) in order to predict the unconfined compressive strength (UCS) of silty soil stabilized with bottom ash (BA), jute fiber (JF) and steel fiber (SF) under different freeze-thaw cycles (FTC). The dosages of the stabilizers and number of freeze-thaw cycles were employed as input (predictor) variables and the UCS values as output variable. For understanding the dominant parameter of the predictor variables on the UCS of stabilized soil, a sensitivity analysis has also been performed. The performance measures of root mean square error (RMSE), mean absolute error (MAE) and determination coefficient ($R^2$) were used for the evaluations of the prediction accuracy and applicability of the employed models. The results indicate that the predictions due to all AI techniques employed are significantly correlated with the measured UCS ($p{\leq}0.05$). They also perform better predictions than nonlinear regression (NLR) in terms of the performance measures. It is found from the model performances that RBNN approach within AI techniques yields the highest satisfactory results (RMSE = 55.4 kPa, MAE = 45.1 kPa, and $R^2=0.988$). The sensitivity analysis demonstrates that the JF inclusion within the input predictors is the most effective parameter on the UCS responses, followed by FTC.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.8
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• pp.3741-3745
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• 2014

Background: Emerging evidence implicates the platelet-derived growth factor-D (PDGF-D) in many types of human solid tumors. We investigated whether PDGF-D plays an important role in endometrial cancer (EC) in relation to clinicopathologic phenotype, angiogenesis, and patient prognosis. Materials and Methods: We analyzed PDGF-D protein expression by Western blotting in twenty-seven human endometrial cancer tissues, and matched normal endometrial controls collected at the third Affiliated hospital of Sun Yat-sen University during 2012-2013 (n=27). Immunohistochemical staining was performed using a human PDGF-D antibody on the endometrial cancer patients collected in the same facility during January 2001 and October 2013 (n=152). Patients were followed from the time of primary surgery in 2001-2013 until death or last follow-up. We correlated the PDGF-D expression levels with clinicopathologic parameters and prognosis in human endometrial cancer patients. Results: Compared with matched normal endometrial cases, PDGF-D was up-regulated in endometrial cancer. Expression of PDGF-D protein, found in 78% of the cases, was associated with nonendometrioid histologic type (p=0.028), FIGO stage III/IV (p=0.039), >50% solid tumor growth (p=0.048), pelvic LN metastasis (p=0.035) and ER and PR negativity (p=0.04 and 0.002). PDGF-D expression was also significantly associated with expression of VEGF-A (p=0.021). In multivariate analysis, PDGF-D expression proved to be an independent prognostic factor in addition to histologic grade and FIGO stage. Patients with high expression levels of PDGF-D had a significantly poorer overall survival rate compared with patients with no expression. Conclusions: PDGF-D expression is frequently up-regulated in endometrial cancer, and is associated with aggressive features and poor prognosis.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.5651-5655
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• 2013

Objective: Major histocompatibility complex class I chain-related A (MICA) is a stress-inducible glycoprotein that can be shed as a soluble protein. This study was conducted to determine the expression of MICA in renal cell carcinoma (RCC) and examine the clinical relevance of soluble MICA (sMICA) in this disease. Methods: Immunohistochemistry and real-time PCR analyses were performed to assess the expression of MICA in 48 pairs of RCC and adjacent normal renal tissues. Serum levels of sMICA were measured in 48 RCC patients, 12 patients with benign renal tumors, and 20 healthy individuals. The correlations between sMICA levels and clinicopathological parameters were analyzed and the diagnostic performance of sMICA in RCC was evaluated. Results: RCCs exhibited elevated expression of MICA compared to adjacent normal tissues. Serum concentrations of sMICA were significantly greater in RCC patients ($348.5{\pm}32.5pg/ml$) than those with benign disease ($289.3{\pm}30.4pg/ml$) and healthy controls ($168.4{\pm}43.2pg/ml$) and significantly correlated with advanced tumor stage, lymph node metastasis, distant metastasis, vascular invasion, and higher histological grade. Using a cut-off point of 250 pg/ml, sMICA demonstrated a specificity and sensitivity of 63.2% and 75.6%, respectively, in distinguishing between RCC and benign renal tumors. Conclusion: MICA expression is upregulated in RCC and increased serum sMICA levels predict aggressive tumor behavior. However, the applicability of sMICA alone is limited in distinguishing RCC from benign renal tumors.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.41 no.10
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• pp.923-929
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• 2017

Generally, the sound emitted from a vehicle powered by an electric motor is lower than that of internal combustion engine vehicles. Therefore, pedestrians often cannot detect approaching electric vehicles. Therefore, a certain additional warning sound is required for these types of automobiles. In this study, to develop an audible warning sound, nine warning sounds are designed based on signal processing and chord theory. The background noise measured on the road is also added to these synthetic sounds. The detectability of these warning sounds is evaluated by subjective tests. The sound metric is correlated to detectability and is investigated through psychoacoustic theory and subjective evaluation. It is determined that known psychoacoustic parameters such as loudness, sharpness, and roughness have a low correlation with detectability. However, it is found that the interval of harmonic sound correlates well with detectability.